橋本敬一郎 (Keiichiro Hashimoto) - マイポータル

基本情報

所属: 藤田医科大学総合医科学研究所医高分子学研究部門教授

学位: 薬学博士(東京大学)

研究者番号: 70192268
J-GLOBAL ID: 201101083825543243
researchmap会員ID: B000001158

外部リンク: http://www.fujita-hu.ac.jp/ICMS/index.html

専門分野：免疫遺伝学、免疫生物学

研究キーワード

研究分野

経歴

2000年 - 現在

藤田保健衛生大学総合医科学研究所, 教授

論文

MR1 discovery

Keiichiro Hashimoto

IMMUNOGENETICS 68(8) 491-498 2016年8月査読有り
Identification of a gene for an ancient cytokine, interleukin 15-like, in mammals; interleukins 2 and 15 co-evolved with this third family member, all sharing binding motifs for IL-15Rα

Dijkstra JM, Takizawa F, Fischer U, Friedrich M, Soto-Lampe V, Lefèvre C, Lenk M, Karger A, Matsui T, Hashimoto K

Immunogenetics 66(2) 93-103 2014年2月査読有り
Cell surface expression of MR1B, a splice variant of the MHC class I-related molecule MR1, revealed with antibodies

Hisateru Yamaguchi, Kentaro Tsukamoto, Keiichiro Hashimoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 443(2) 422-427 2014年1月査読有り
Comprehensive analysis of MHC class II genes in teleost fish genomes reveals dispensability of the peptide-loading DM system in a large part of vertebrates

Johannes M. Dijkstra, Unni Grimholt, Jong Leong, Ben F. Koop, Keiichiro Hashimoto

BMC Evolutionary Biology 13(1) 260 2013年11月26日査読有り
Exceptionally high conservation of the MHC class I-related gene, MR1, among mammals

Kentaro Tsukamoto, Janine E. Deakin, Jennifer A. Marshall Graves, Keiichiro Hashimoto

Immunogenetics 65(2) 115-124 2013年2月査読有り
Constitutive high expression of interleukin-4/13A and GATA-3 in gill and skin of salmonid fishes suggests that these tissues form Th2-skewed immune environments

Fumio Takizawa, Erling Olaf Koppang, Maki Ohtani, Teruyuki Nakanishi, Keiichiro Hashimoto, Uwe Fischer, Johannes Martinus Dijkstra

MOLECULAR IMMUNOLOGY 48(12-13) 1360-1368 2011年7月査読有り
A molecule in teleost fish, related with human MHC-encoded G6F, has a cytoplasmic tail with ITAM and marks the surface of thrombocytes and in some fishes also of erythrocytes

Ken Ohashi, Fumio Takizawa, Norihiro Tokumaru, Chihaya Nakayasu, Hideaki Toda, Uwe Fischer, Tadaaki Moritomo, Keiichiro Hashimoto, Teruyuki Nakanishi, Johannes Martinus Dijkstra

IMMUNOGENETICS 62(8) 543-559 2010年8月査読有り
Zinc-dependent binding between peptides derived from rainbow trout CD8 alpha and LCK

Nobuhiro Hayashi, Masami Takeuchi, Teruyuki Nakanishi, Keiichiro Hashimoto, Johannes Martinus Dijkstra

FISH & SHELLFISH IMMUNOLOGY 28(1) 72-76 2010年1月査読有り
Comprehensive clarification of two paralogous interleukin 4/13 loci in teleost fish

Maki Ohtani, Nobuhiro Hayashi, Keiichiro Hashimoto, Teruyuki Nakanishi, Johannes Martinus Dijkstra

IMMUNOGENETICS 60(7) 383-397 2008年7月査読有り
A third broad lineage of major histocompatibility complex (MHC) class I in teleost fish; MHC class II linkage and processed genes.

Johannes Martinus Dijkstra, Takayuki Katagiri, Kazuyoshi Hosomichi, Kazuyo Yanagiya, Hidetoshi Inoko, Mitsuru Ototake, Takashi Aoki, Keiichiro Hashimoto, Takashi Shiina

Immunogenetics 59(4) 305-21 2007年4月査読有り
Molecular cloning of C4 gene and identification of the class III complement region in the shark MHC.

Terado T, Okamura K, Ohta Y, Shin DH, Smith SL, Hashimoto K, Takemoto T, Nonaka MI, Kimura H, Flajnik MF …

Journal of immunology (Baltimore, Md. : 1950) 171(5) 2461-2466 2003年9月1日査読有り
Classical MHC class I genes composed of highly divergent sequence lineages share a single locus in rainbow trout (Oncorhynchus mykiss).

Aoyagi K, Dijkstra JM, Xia C, Denda I, Ototake M, Hashimoto K, Nakanishi T

Journal of immunology (Baltimore, Md. : 1950) 168(1) 260-273 2002年1月1日査読有り
Association of MR1 protein, an MHC class I-related molecule, with beta(2)-microglobulin

H Yamaguchi, K Hashimoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 290(2) 722-729 2002年1月査読有り
Primitive synteny of vertebrate major histocompatibility complex class I and class II genes

Y Ohta, K Okamura, EC McKinney, S Bartl, K Hashimoto, MF Flajnik

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA 97(9) 4712-4717 2000年4月査読有り
Conservation and diversification of MHC class I and its related molecules in vertebrates

K Hashimoto, K Okamura, H Yamaguchi, M Ototake, T Nakanishi, Y Kurosawa

IMMUNOLOGICAL REVIEWS 167 81-100 1999年2月査読有り
Expanded genomic organization of conserved mammalian MHC class I-related genes, human MR1 and its murine ortholog

H Yamaguchi, Y Kurosawa, K Hashimoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 250(3) 558-564 1998年9月査読有り
The most primitive vertebrates with jaws possess highly polymorphic MHC class I genes comparable to those of humans

K Okamura, M Ototake, T Nakanishi, Y Kurosawa, K Hashimoto

IMMUNITY 7(6) 777-790 1997年12月査読有り
A highly conserved major histocompatibility complex class I-related gene in mammals

H Yamaguchi, M Hirai, Y Kurosawa, K Hashimoto

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 238(3) 697-702 1997年9月査読有り
Identification of a mouse homolog for the human hereditary haemochromatosis candidate gene

K Hashimoto, M Hirai, Y Kurosawa

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 230(1) 35-39 1997年1月査読有り
A gene outside the human MHC related to classical HLA class I genes.

Hashimoto K, Hirai M, Kurosawa Y

Science (New York, N.Y.) 269(5224) 693-695 1995年8月4日査読有り

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