Kasahara Yuka

Profile Information

Degree: 博士(Oct, 2019)

J-GLOBAL ID: 201801010702764495
researchmap Member ID: 7000024305

External link: http://www-user.yokohama-cu.ac.jp/~pharmac/index.html

Research Interests

Research Areas

Research History

Apr, 2021 - Present

Faculty of Medical Sciences, Kyushu University
Apr, 2020 - Mar, 2021

assistant professor, Graduate School of Medicine, Graduate, Yokohama City University
Sep, 2018 - Mar, 2020

Graduate School of Medicine, Graduate, Yokohama City University
Apr, 2017 - Aug, 2018

特別研究員 (DC2), 日本学術振興会

Education

Apr, 2015 - Aug, 2018

薬学系研究科, 東京大学大学院
Apr, 2009 - Mar, 2015

薬学部薬学科, 慶応義塾大学

Awards

Aug, 2017

ポスター発表賞, 生体機能と創薬シンポジウム2017
May, 2016

Platinum award, 第2回 Young Glia Meeting

Papers

Seizure-induced hilar ectopic granule cells in the adult dentate gyrus.

Yuka Kasahara, Hideyuki Nakashima, Kinichi Nakashima

Frontiers in neuroscience, 17 1150283-1150283, 2023
L-DOPA-Induced Neurogenesis in the Hippocampus Is Mediated through GPR143, a Distinct Mechanism of Dopamine.

Yuka Kasahara, Daiki Masukawa, Kenta Kobayashi, Miwako Yamasaki, Masahiko Watanabe, Yoshio Goshima

Stem cells (Dayton, Ohio), 40(2) 215-226, Jan 19, 2022
Genetic associations of single nucleotide polymorphisms in the l-DOPA receptor (GPR143) gene with severity of nicotine dependence in Japanese individuals, and attenuation of nicotine reinforcement in Gpr143 gene-deficient mice.

Daiki Masukawa, Daisuke Nishizawa, Kaori Kanai, Satoshi Kitamura, Yuka Kasahara, Tatsuo Hashimoto, Ryo Takahagi, Junko Hasegawa, Kyoko Nakayama, Naomi Sato …

Journal of pharmacological sciences, 144(2) 89-93, Oct, 2020 Peer-reviewed
Distribution of mRNA for GPR143, a receptor of 3,4-L-dihydroxyphenylalanine, and of immunoreactivities for nicotinic acetylcholine receptors in the nigrostriatal and mesolimbic regions.

Yuka Kasahara, Daiki Masukawa, Yoshie Nakamura, Koshi Murata, Tatsuo Hashimoto, Kohtaro Takizawa, Motokazu Koga, Fumio Nakamura, Yugo Fukazawa, Kengo Funakoshi …

Neuroscience research, 170 370-375, Sep 5, 2020 Peer-reviewed
The Pharmacological Assessment of GABAA Receptor Activation in Experimental Febrile Seizures in Mice

Yuka Kasahara, Hideyoshi Igata, Takuya Sasaki, Yuji Ikegaya, Ryuta Koyama

eNeuro, 6(1), May 4, 2019 Peer-reviewedLead author
l-DOPA and Its Receptor GPR143: Implications for Pathogenesis and Therapy in Parkinson's Disease.

Yoshio Goshima, Daiki Masukawa, Yuka Kasahara, Tatsuo Hashimoto, Aderemi Caleb Aladeokin

Frontiers in pharmacology, 10 1119-1119, 2019 Peer-reviewed
Neonatal Seizure models to study epileptogenesis

Yuka Kasahara, Yuji Ikegaya, Ryuta Koyama

Frontiers in Pharmacology, 9 385, Apr 18, 2018 Peer-reviewed
[Mouse model of febrile seizures].

Kasahara Y, Ikegaya Y, Koyama R

Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 150(5) 240-245, 2017 Peer-reviewed
Depth and time-dependent heterogeneity of microglia in mouse hippocampal slice cultures

Yuka Kasahara, Ryuta Koyama, Yuji Ikegaya

NEUROSCIENCE RESEARCH, 111 64-69, Oct, 2016 Peer-reviewed

Presentations

痙攣発作誘導後に生じる海馬の病理的変化におけるGPR143の関与

柴田龍之介, 笠原由佳, 五嶋良郎

第93回日本薬理学会年会, Mar, 2020
熱性けいれんフェノタイプに対するGABAA受容体賦活薬の影響

笠原由佳

生体機能と創薬シンポジウム2019, Aug 30, 2019
The effects of GABAA receptor modulators on experimental febrile seizures

笠原由佳, 井形秀吉, 佐々木拓哉, 池谷裕二, 小山隆太

第92回日本薬理学会年会, Mar, 2019
Microglia regulate the development of dentate neural circuits

笠原由佳, 上田英輝, 池谷裕二, 小山隆太

第18回東京大学生命科学シンポジウム, Jun 9, 2018
熱性けいれんフェノタイプに対するGABA受容体作用薬の影響

笠原由佳, 井形秀吉, 佐々木拓哉, 小山隆太, 池谷裕二

第138回日本薬理学会関東部会, Mar 10, 2018
Microglia trim dentate synapses during development.

Kasahara Y, Ueda H, Koyama R, Ikegaya Y

Society for Neuroscience 2017, Nov, 2017
Neonatal GABA signalings modulate seizure phenotypes.

Kasahara Y, Igata H, Sasaki T, Ikegaya Y, Koyama R

第9回光操作研究会, Nov, 2017
歯状回の神経回路形成におけるマイクログリアの関与

笠原由佳, 上田英輝, 小山隆太, 池谷裕二

次世代を担う創薬・医療薬理シンポジウム2017, Aug 26, 2017
マイクログリアによる歯状回神経回路の精密化

笠原由佳, 上田英輝, 小山隆太, 池谷裕二

生体機能と創薬シンポジウム2017, Aug 25, 2017
Hyperthermia activates microglia to engulf inhibitory synapses in early-life seizures

Koyama R, Kasahara Y, Shibata K, Ujita S, Sugino S, Tanaka KF, Shibasaki K, Ikegaya Y

Society for Neuroscience 2016, Nov, 2016
培養スライス標本深度に依存したマイクログリア構造および活性化状態の変化

笠原由佳, 小山隆太, 池谷裕二

第39回日本神経科学大会, Jul, 2016
Fever activates microglia to engulf inhibitory synapses and lower the seizure threshold

Koyama R, Kasahara Y, Shibata R, Ujita S, Sugino S, Tanaka J, Shibasaki K, Ikegaya Y

The 18th Annual Meeting of Infantile Seizure Society, Jun, 2016
Neural circuit formation of mossy fiber during development period

Kasahara Y, Ueda H, Ikegaya Y, Koyama R

第2回 Young Glia Meeting, May, 2016

Professional Memberships

2017 - Present

Society for Neuroscience
2016 - Present

日本薬理学会
2014 - Present

日本神経化学学会
2014 - Present

日本薬学会
2014 - Present

日本神経科学学会

Research Projects

熱性けいれんに伴う神経回路変性における神経細胞ーミクログリア連関分子機構の解明

科学研究費助成事業若手研究, 若手研究, 日本学術振興会, Apr, 2021 - Mar, 2024

笠原由佳
Involvement of GPR143 in the regulation of dopamine D2 receptor signaling

Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2021

KASAHARA Yuka

Profile Information

Research Interests

Research Areas

Research History

Education

Awards

Papers

Presentations

Professional Memberships

Research Projects

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