Akira Sasaki

J-GLOBAL         Last updated: Oct 24, 2016 at 17:23
 
Avatar
Name
Akira Sasaki
Affiliation
Graduate University for Advanced Studies (Sokendai)
Section
Department of Evolutionary Studies of Biosystems
Job title
Professor
Degree
Ph D

Profile

Akira Sasaki joined the Department of Evolutionary Studies of Biosystems at SOKENDAI in July 2007 as a Professor of Mathematical Biology.

Dr. Sasaki received his Ph.D. from Kyushu University in 1989. He became Assistant Professor of mathematical biology at Kyushu University in 1989. From 1996 to June 2007, he has been Associate Professor of mathematical biology at Kyushu University. He has been a visiting research fellow at North Carolina State University, USA (1993-1994), the University of Utrecht, the Netherlands (1997), University College London Silwood Park, UK (1998, 1999), Oxford University, UK (1998, 1999), Institute for Advanced Study, Princeton, USA (2001-2002), and Harvard University, USA (2003). Since September 2005, he has been a research associate of the Evolution and Ecology Program at International Institute for Applied Systems Analysis (IIASA), Laxenburg, Austria. From October 2007 to March 2011, he has been a JST PRESTO researcher.

He is working on the stochastic theory of population genetics, host-parasite coevolution, species packing theory, spatially explicit models of ecology and epidemiology, intrahost dynamics of pathogen and immune system, bet-hedging in changing environment, evolution of cooperation, evolution of mutability in fitness landscapes, restriction avoidance and the evolution of word frequency in phage genome, spatial mosaic formation in Müllerian mimicry system, epidemiology and evolution of virulence in small worlds networks, and on other problems in theoretical population biology.

Published Papers

 
Spotting Epidemic Keystones by R0 Sensitivity Analysis: High-Risk Stations in the Tokyo Metropolitan Area
K. Yashima, A. Sasaki
PLosS ONE   11 e0162406   2016   [Refereed]
Evolutionary branching under multi-dimensional evolutionary constraints
H. Ito, A. Sasaki
J. Theor. Biol.   407 409-428   2016   [Refereed]
Beyond pairs: Definition and interpretation of third-order structure in spatial point patterns
C. Kaito, U. Dieckmann, A. Sasaki, F. Takasu
J. Theor. Biol.   372 22-38   2016   [Refereed]
Masato Yamamichi, Takehito Yoshida, Akira Sasaki
Ecology   95 2303-2315   Aug 2014   [Refereed]
Kenta Yashima, Akira Sasaki
PLoS ONE   9(6) e98518   2014   [Refereed]
Emmanuel A. Mpolya, Kenta Yashima, Hisashi Ohtsuki, Akira Sasaki
Journal of Theoretical Biology   343 120-126   Feb 2014   [Refereed]
Olof Leimar, Akira Sasaki, Michael Doebeli, Ulf Dieckmann
Journal of Theoretical Biology   339 3-13   Dec 2013   [Refereed]
Ryosuke Omori, Akira Sasaki
Journal of Theoretical Biology   329 32-38   Jul 2013   [Refereed]
Masato Yamamichi, Akira Sasaki
Evolution   67 2011-2023   Mar 2013   [Refereed]
Akira Sasaki, Yoshihiro Haraguchi, Hiromu Yoshida
Frontiers in Microbiology   3 Article number: 178   May 2012   [Refereed]
Masaki Fukuyo, Akira Sasaki, Ichizo Kobayashi
Scientific Reports   2 Article number: 238   Jan 2012   [Refereed]
Naoyuki Iseki, Akira Sasaki, Hirokazu Toju
Journal of Theoretical Biology   285(1) 1-9   Sep 2011   [Refereed]
Masato Yamamichi, Takehito Yoshida, Akira Sasaki
American Naturalist   178(3) 287-304   Jul 2011   [Refereed]
Sayaki U. Suzuki, Akira Sasaki
Journal of Theoretical Biology   276(1) 117-125   May 2011   [Refereed]
Jun Nakabayashi, Akira Sasaki
Journal of Theoretical Biology   269(1) 318-329   Jan 2011   [Refereed]
Akira Sasaki and Ulf Dieckmann
Journal of Mathematical Biology   63 601-635   2011   [Refereed]
Ryosuke Omori, Ben Adams, Akira Sasaki
Journal of Theoretical Biology   262 48-57   Jan 2010   [Refereed]
Jun Nakabayashi, Akira Sasaki
Journal of Theoretical Biology   261 156-164   Nov 2009   [Refereed]
Ben Adams, Akira Sasaki
Theoretical Population Biology   76(3) 157-167   Nov 2009   [Refereed]
Koji Yahara, Masaki Fukuyo, Akira Sasaki, Ichizo Kobayashi
Proceedings of the National Academy of Sciences of the United States of America   106(44) 18861-18866   Nov 2009   [Refereed]
Jun Nakabayashi, Akira Sasaki
Journal of Theoretical Biology   259 389-403   Jul 2009   [Refereed]
Ben Adams, Akira Sasaki
Mathematical Biosciences   210 680-699   Dec 2007   [Refereed]
Koji Yahara, Ryota Horie, Ichizo Kobayashi, Akira Sasaki
Genetics   176(1) 513-526   Mar 2007   [Refereed]
The role of trade-off shapes in the evolution of parasites in spatial host populations: An approximate analytical approach.
Kamo, M., Sasaki, A., and Boots, M.
Journal of Theoretical Biology   244 588-596   Feb 2007   [Refereed]
The wave speed of intergradation zone in two-species lattice Mullerian mimicry model.
Kawaguchi, I., and Sasaki, A.
Journal of Theoretical Biology   243 594-603   Dec 2006   [Refereed]
A mathematical model for apoptosome assembly: The optimal cytochrome c/Apaf-1 ratio.
Nakabayashi, J., and Sasaki, A.
Journal of Theoretical Biology   242 280-287   Sep 2006   [Refereed]
Andreasen, V., and Sasaki, A.
Theoretical Population Biology   70(2) 164-173   Sep 2006   [Refereed]
The greater than twofold cost of integration for retroviruses.
Krakauer, D.C., and Sasaki, A.
Proceedings of the Royal Society B   273 1159-1163   May 2006   [Refereed]
Epidemiology and disease-control under gene-for-gene plant-pathogen interaction.
Ohtsuki, A., and Sasaki, A.
Journal of Theoretical Biology   238 780-794   Feb 2006   [Refereed]
Optimal phosphorylation step number of intracellular signal-transduction pathway.
Nakabayashi, J., and Sasaki, A.
Journal of Theoretical Biology   233 413-421   Apr 2005   [Refereed]
Kamo, M., and Sasaki, A.
Ecology Letters   8(4) 378-385   2005   [Refereed]
Evolutionary game dynamics in finite populations.
Taylor, C., Fudenberg, D., Sasaki, A., and Nowak, M.A.
Bulletin of Mathematical Biology   66 1621-1644   Nov 2004   [Refereed]
Apparent competition and recovery from infection.
Wodarz, D., and Sasaki, A.
Journal of Theoretical Biology   227 403-412   Apr 2004   [Refereed]
Evolution of hierarchical cytoplasmic inheritance in plasmodial slime mould, Physarum polycephalum.
Iwanaga, A., and Sasaki, A.
Evolution   58 710-722   Apr 2004   [Refereed]
Nowak, M.A., Sasaki, A., Taylor, C., and Fudenberg, D.
Nature   428(6983) 646-650   Apr 2004   [Refereed]
Boots, M., Hudson, P.J., and Sasaki, A.
Science   303(5659) 842-844   Feb 2004   [Refereed]
Combining zooprophylaxis and insecticide spraying: a malaria-control strategy limiting the development of insecticide resistance in vector mosquitoes.
Kawaguchi, I., Sasaki, A., and Mogi, M.
Proceedings of the Royal Society of London B   271 301-309   Feb 2004   [Refereed]
Mutation landscapes.
Sasaki, A., and Nowak, M.A.
Journal of Theoretical Biology   224 241-247   Sep 2003   [Refereed]
Can transitive inference evolve in animals playing hawk-dove game?
Nakamaru, M., and Sasaki, A.
Journal of Theoretical Biology   222 461-470   2003   [Refereed]
Why are dengue virus serotypes so distantly related? -- Enhancement and limiting serotype similarity between strains.
Kawaguchi, I., Sasaki, A., and Boots, M.
Proceedings of the Royal Society of London B   270 2241-2247   Nov 2003   [Refereed]
Boots, M., and Sasaki, A.
Ecology Letters   6(3) 176-182   2003   [Refereed]
Spatial mosaic and interfacial dynamics in Mullerian mimicry system.
Sasaki, A., Kawaguchi, I., and Yoshimori, A.
Theoretical Population Biology   61 49-71   Feb 2002   [Refereed]
Clone mixtures and a pacemaker: new facets of Red-Queen theory and ecology.
Sasaki, A., Hamilton, W.D., and Ubeda, F.
Proceedings of the Royal Society of London B   269 761-772   2002   [Refereed]
Noisy clues to the origin of life.
Krakauer, D.C., and Sasaki, A.
Proceedings of the Royal Society of London B   269 2423-2428   Dec 2002   [Refereed]
The effect of cross-immunity and seasonal forcing in a multi-strain epidemic model.
Kamo, M., and Sasaki, A.
Physica D-Nonlinear Phenomena   165 228-241   2002   [Refereed]
Modeling host-parasite coevolution: A nested approach based on mechanistic models.
Gilchrist, M., and Sasaki, A.
Journal of Theoretical Biology   218 289-308   2002   [Refereed]
Parasite-driven extinction in spatially explicit host-parasite systems.
Boots, M., and Sasaki, A.
American Naturalist   159 706-713   Jun 2002   [Refereed]
Variable timing of reproduction in unpredictable environments: adaptation of flood plain plants.
Satake, A., Sasaki, A., and Iwasa, Y.
Theoretical Population Biology   60 1-15   2001   [Refereed]
Antigenic drift of viruses within a host: A finite site model with demographic stochasticity.
Sasaki, A., and Haraguchi, Y.
Journal of Molecular Evolution   51 245-255   2000   [Refereed]
Host-parasite coevolution in multilocus gene-for-gene system.
Sasaki, A.
Proceedings of the Royal Society of London B   267 2183-2188   2000   [Refereed]
Evolution of parasite virulence and transmission rate in a spatially structured population.
Haraguchi, Y., and Sasaki, A.
Journal of Theoretical Biology   203 85-96   2000   [Refereed]
Boots, M., and Sasaki, A.
Ecology Letters   3(3) 181-185   2000   [Refereed]
A model for the coevolution of resistance and virulence in coupled host-parasitoid interactions.
Sasaki, A., and Godfray, H.C.J.
Proceedings of the Royal Society of London B   266 455-463   1999   [Refereed]
Density dependence and unpredictable selection in a heterogeneous environment: Compromise and polymorphism in the ESS reaction norm.
Sasaki, A., and de Jong, G.
Evolution   53 1329-1342   1999   [Refereed]
`Small worlds' and the evolution of virulence: infection occurs locally and at a distance.
Boots, M., and Sasaki, A.
Proceedings of the Royal Society of London B   266 1933-1938   Oct 1999   [Refereed]
Speed of invasion in lattice population models: pair-edge approximation.
Ellner, S.P., Sasaki, A., Haraguchi, Y., and Matsuda, H.
Journal of Mathematical Biology   36 469-484   1998   [Refereed]
Quantitative genetic variance maintained by fluctuating selection with overlapping generations: Variance components and covariances.
Sasaki, A., and Ellner, S.
Evolution   51 682-696   1997   [Refereed]
Clumped distribution by neighborhood competition.
Sasaki, A.
Journal of Theoretical Biology   186 415-430   1997   [Refereed]
Haraguchi, Y., and Sasaki, A.
Philosophical Transactions of the Royal Society of London B   352(1349) 11-20   1997   [Refereed]
Host-parasite arms race in mutation modifications: Indefinite escalation despite a heavy load?
Haraguchi, Y., and Sasaki, A.
Journal of Theoretical Biology   183 121-137   1996   [Refereed]
Patterns of genetic polymorphism maintained by fluctuating selection with overlapping generations.
Ellner, S., and Sasaki, A.
Theoretical Population Biology   50 31-65   1996   [Refereed]
The evolutionarily stable phenotype distribution in a random environment.
Sasaki, A., and Ellner, S.
Evolution   49 337-350   1995   [Refereed]
Pathogen invasion and host extinction in lattice structured populations.
Sato, K., Matsuda, H., and Sasaki, A.
Journal of Mathematical Biology   32 251-268   1994   [Refereed]
Evolution of antigen drift/switching - continuously evading pathogens.
Sasaki, A.
Journal of Theoretical Biology   168 291-308   1994   [Refereed]
Matsuda, H., Ogita, N., Sasaki, A., and Sato, K.
Progress of Theoretical Physics   88(6) 1035-1049   1992   [Refereed]
Optimal growth schedule of pathogens within a host: Switching between lytic and latent cycles.
Sasaki, A., and Iwasa, Y.
Theoretical Population Biology   39 201-239   1991   [Refereed]
Evolutionarily stable mutation rate in a periodically fluctuating environment.
Ishii, K., Matsuda, H., Iwasa, Y., and Sasaki, A.
Genetics   121 163-174   1989   [Refereed]
Evolution of the number of sexes
Iwasa, Y., and Sasaki, A.
Evolution   41 49-65   1987   [Refereed]
Optimal recombination rate in fluctuating environments
Sasaki, A., and Iwasa, Y.
Genetics   115 337-388   1987   [Refereed]
Factors affecting the number of children in five developed countries: A statistical analysis with an evolutionary perspective
Akira Sasaki
   [Refereed]

Books etc

 
The implications of spatial structure within populations to the evolution of parasites, in: Feng, Z., et al., Eds.), Disease evolution: Models, concepts, and data analyses, pp. 3-22.
Boots, M., Kamo, M., and Sasaki, A.
American Mathematical Society   2006   
Coevolution in gene-for-gene systems, in: Diekmann, U., et al., Eds.), Adaptive Dynamics of Infectious Diseases: In pursuit of virulence management, pp. 233-247.
Akira Sasaki
Cambridge University Press,   2002   
What can evolutionary biology contribute to understanding virulence?, in: Stearns, S., (Ed.), Evolution in Health and Disease, pp. 205-215.
Read, A.F., Aaby, P., Antia, R., Ebert, D., Ewald, P.W., Gupta, S., Holmes, E.C., Sasaki, A., Shields, D., Taddei, F., and Moxon, E.R.
Oxford University Press   1999   
The evolution of host and pathogen genes under epidemiological interaction. In Takahata, N., (Ed.), Population Pareo-Genetics. Proceeding of The Seventeenth Taniguchi International Symposium on Biophysics, pp. 247-263.
Akira Sasaki
Japan Scientific Society Press   1992   
A lattice model for population biology, Mathematical topics in population biology, morphogenesis and neurosciences (Lecture Notes in Biomathematics, 71)
Matsuda, H., Tamachi, N., Ogita, N., and Sasaki, A.
Springer   1987   
Evolution of the number of sexe. In Mathematical topics in population biology, morphogenesis and neurosciences (Lecture Notes in Biomathematics, 71), pp. 144-153.
Yoh Iwasa and Akira Sasaki
Springer   1987   

Conference Activities & Talks

 
The coevolution of human antiviral protein APOBEC3G and HIV protein Vif: A theoretical study [Invited]
Akira Sasaki
Symposium “Mathematical modeling for emerging infectious diseases.” Joint Meeting of The 5th China-Japan-Korea Colloquium on Mathematical Biology and The Japanese Society for Mathematical Biology, August 26 - 29, 2015, Doshisha University, Kyoto, Japan   27 Aug 2015   
Discrete Species Packing and Evolved Neutrality in a Continuous Niche Space [Invited]
Akira Sasaki
Gordon Research Conference, Speciation 2015. Ventura, California, USA. March 15-20, 2015   15 Mar 2015   
Projecting evolutionary trajectory of influenza A virus: Multidimensional scaling and individual based antigenic drift model [Invited]
Akira Sasaki
ICMMA 2014 'Crowd Dynamics', January 12, 2015, Meiji University, Tokyo   12 Jan 2015   
Akira Sasaki
Symposium "Dynamic interplay between viruses and their hosts", Pacifico Yokohama, Yokohama, November 8-9, 2014   9 Nov 2014   
Akira Sasaki
JSMB/SMB 2014 Osaka. Minisymposium: "Understanding mimicry -- evolutionary and developmental dynamics of signal sharing, Osaka, July 29-August 1, 2014   31 Jul 2014   
Akira Sasaki
JSMB/SMB 2014 Osaka. Minisymposium: "Dynamics of experimental evolution -- arms race and self-organization", Osaka, July 28-August 1, 2014.   29 Jul 2014   
Akira Sasaki
The 11th Conference of European Society for Mathematical and Theoretical Biology (ESMTB 2014), Gothenburg, Sweden, June 15-19, 2014   16 Jun 2014   
Akira Sasaki
Workshop "Spatial evolutionary epidemiology,” Organisers: Sébastien Lion and Sylvain Gandon Centre d’Écologie Évolutive et Fonctionnelle (CNRS UMR 5175), Montpellier, France, June 3-7, 2014   5 Jun 2014   
Projecting evolutionary trajectory of influenza A virus: Multidimensional scaling and individual based antigenic drift model
Akira Sasaki
Tsukuba Global Science Week 2013: International Life Science Workshop -- Systems Biology   3 Oct 2013   
Akira Sasaki
8th European Conference on Mathematical Biology (ECMTB 2011), June 28-July 2, 2011, Krakow, Poland   Jun 2011   
Akira Sasaki
Mathematica Biosciences Institute Workshop 5: Coevolution and the Ecological Structure of Plant-insect Communities, April 4-7, 2011, Ohio State University, Columbus, USA   Apr 2011   
Akira Sasaki
Winter school on eco-evolutionary modeling of speciation, Abisko Science Station, Sweden March 7-11, 2011 (Lectures)   Mar 2011   An ESF Research Networking Program, Frontiers of Speciation Research
Akira Sasaki
Mathematical Models and Experimental Microbial Systems Workshop, Coevolution: Models and microbial model system, 2010 April 14-15, Liverpool, UK.   Apr 2010   
Emergence probability of new flu escape variants: Be aware of early stage mutants and of spring outbreak [Invited]
Akira Sasaki
BICS Conference Multiply Structured Populations in Biology, University of Bath, Bath, UK, July 1, 2009   Jul 2009