Department of Biological Science, Graduate School of Science
Job title
Assistant Professor
Degree
PhD
Research funding number
00376534
Profile
To clarify both molecular/neural basis and brain information processing underlying social interactions in vertebrates, we have focused on Medaka fish and established novel behavior systems to assess social interactions (schooling behavior, individual recognition, group-escape and group-learning). Using these systems we are planning to identify internal factors (genes, neural networks, and brain regions) essential for vertebrate social interactions using transgenic medaka systems. On the other hand, to estimate brain information processing underlying social interactions, we developed a mathematical modeling, which could explain actual fish movement. Our eventual purpose is to identify the internal factors, which can correspond to “modules and/or parameters” in the algorithms using a combined mathematical modeling and molecular biological approach.
Furthermore I have investigated the molecular/neural basis underlying invertebrate social behavior (honeybee) and searched the conserved neural mechanism between the vertebrate and invertebrate.
Hori S, Takeuchi H†, Arikawa K, Kinoshita M, Ichikawa N, Sasaki M, Kubo T †Corresponding
Journal of Comparative Physiology. A, Neuroethology, Sensory, Neural, and Behavioral Physiology 192 691-700 Jul 2006 [Refereed]
Differential expression of HR38 in the mushroom bodies of the honeybee brain depends on the caste and division of labor.
Yamazaki Y*, Shirai K*, Paul RK, Fujiyuki T, Wakamoto A, Takeuchi H, and Kubo T.
FEBS Lett. 580 2667-2670 2006 [Refereed]
Division of labor in the honey bee (Apis mellifera): The role of tyramine beta-hydroxylase
Lehman HK, Schulz DJ, Barron AB, Wraight L, Hardison C, Whitney S, Takeuchi H, Paul RK, and Robinson GE
J. Exp.Biol. 209 2774-2784 2006 [Refereed]
Prevalence and phylogeny of Kakugo virus, a novel insect picorna-like virus that infects the honeybee (Apis mellifera L.), under various colony conditions.
Fujiyuki T, Ohka S, Takeuchi H, Ono M, Nomoto A, and Kubo T.
J. Virol. 80 11528-11538 2006 [Refereed]
Carbohydrate metabolism genes and pathways in insects: insights from the honey bee genome.
Kunieda T*, Fujiyuki T*, Kucharski R*, Foret S*, Ament SA*, Toth AL*, Ohashi K, Takeuchi H, Kamikouchi A, Kage E, Morioka M, Beye M, Kubo T, Robinson GE, and Maleszka R.
Insect Mol. Biol. 15 563-576 2006 [Refereed]
Insights into social insects from the genome of the honey bee Apis mellifera.
Takeuchi H, Yasuda A, Yasuda-Kamatani Y, Sawata M, Matsuo Y, Kato A, Tsujimoto A, Nakajima T, Kubo T
Cell and Tissue Research 316 281-293 May 2004 [Refereed]
Novel insect picorna-like virus identified in the brains of aggressive worker honeybees.
Fujiyuki T, Takeuchi H, Ono M, Ohka S, Sasaki T, Nomoto A, Kubo T
Journal of Virology 78 1093-1100 Feb 2004 [Refereed]
(Selected as the cover)
Identification and characterization of Mlr1, 2: two mouse homologues of Mblk-1, a transcription factor from the honeybee brain.
Kunieda T, Park JM, Takeuchi H, and Kubo T.
FEBS lett. 525 61-65 2003 [Refereed]
Identification of a tachykinin-related neuropeptide from the honeybee brain using direct MALDI-TOF MS and its gene expression in worker, queen, and drone heads.
Takeuchi H*, Yasuda A*, Yasuda-Kamatani Y*, Kubo T, and Nakajima T.
Insect Mol. Biol. 12 291-298 2003 [Refereed]
Identification of genes expressed preferentially in the honeybee mushroom bodies by combination of differential display and cDNA microarray.
Takeuchi H, Fujiyuki T, Shirai K, Matsuo Y, Kamikouchi A, Fujinawa Y, Kato A, Tsujimoto A, Kubo T
Biochemical and Biophysical Research Communications 291 23-28 Feb 2002 [Refereed]
Identification and punctate nuclear localization of a novel noncoding RNA, Ks-1, from the honeybee brain.
Sawata M, Yoshino D, Takeuchi H, Kamikouchi A, Ohashi K, and Kubo T.
RNA 8 772-785 2002 [Refereed]
Identification of a novel gene, Mblk-1, that encodes a putative transcription factor expressed preferentially in the large-type Kenyon cells of the honey bee brain.
Takeuchi H, Kage E, Sawata M, Kamikouchi A, Ohashi K, Ohara M, Fujiyuki T, Kunieda T, Sekimizu K, Natori S, and Kubo T.
Insect Mol. Biol. 10 487-494 2001 [Refereed]
Concentrated expression of Ca2+/ calmodulin-dependent protein kinase II and protein kinase C in the mushroom bodies of the brain of the honeybee Apis mellifera L.
Kamikouchi A, Takeuchi H, Sawata M, Natori S, and Kubo T.
J. Comp. Neurol. 417 501-510 2000 [Refereed]
Soldier caste-specific gene expression in the mandibular glands of Hodotermopsis japonica (Isoptera: termopsidae).
Miura T, Kamikouchi A, Sawata M, Takeuchi H, Natori S, Kubo T, and Matsumoto T.
Proc. Natl. Acad. Sci. USA 96 13874-13879 1999 [Refereed]
Preferential expression of the gene for a putative inositol 1,4,5-trisphosphate receptor homologue in the mushroom bodies of the brain of the worker honeybee Apis mellifera L.
Kamikouchi A, Takeuchi H, Sawata M, Ohashi K, Natori S, and Kubo T.
biol.s.u-tokyo.ac.jp
