Kazuo Kitamura

Profile Information

Affiliation: 教授, 大学院総合研究部医学域, 山梨大学

Degree: Ph.D.(1998, Osaka University)

J-GLOBAL ID: 200901033013556575
researchmap Member ID: 5000089322

External link: https://scholar.google.com/citations?user=eZwXMaoAAAAJ&hl=en

Research Interests

Research Areas

Education

- 1998

Department of Biophysical Engineering, Graduate School of Engineering Science, Osaka University
- 1993

Department of Biophysical Engineering, Faculty of Engineering Science, Osaka University

Research History

2014 - Present

Graduate Faculty of Interdisciplinary Research Faculty of Education, Education (Childhood developmental education), University of Yamanashi
2010 - 2014

准教授, 東京大学医学系研究科
2007 - 2010

助教, 東京大学医学系研究科
2005 - 2007

助手, 大阪大学医学系研究科
2003 - 2005

研究員, ウルフソン生物医学研究所, ユニバーシティ・カレッジ・ロンドン
1998 - 2003

研究員, 一分子過程プロジェクト, 科学技術振興事業団

Awards

Apr, 2010

科学技術分野の文部科学大臣表彰若手科学者賞, 文部科学省

喜多村和郎
Mar, 2001

井上研究奨励賞, （財）井上科学振興財団

喜多村和郎

Papers

Optogenetic stimulation of neurons in the anterior cingulate cortex induces changes in intravesical bladder pressure and the micturition reflex.

Takanori Mochizuki, Satoshi Manita, Hiroshi Shimura, Satoru Kira, Norifumi Sawada, Haruhiko Bito, Kenji Sakimura, George J Augustine, Takahiko Mitsui, Masayuki Takeda …

Scientific reports, 14(1) 6367-6367, Mar 16, 2024
Dynamic organization of cerebellar climbing fiber response and synchrony in multiple functional components reduces dimensions for reinforcement learning

Huu Hoang, Shinichiro Tsutsumi, Masanori Matsuzaki, Masanobu Kano, Mitsuo Kawato, Kazuo Kitamura, Keisuke Toyama

eLife, 12 e86340, Sep 15, 2023 Peer-reviewedCorresponding author
Cerebellar climbing fibers multiplex movement and reward signals during a voluntary movement task in mice

Koji Ikezoe, Naoki Hidaka, Satoshi Manita, Masayoshi Murakami, Shinichiro Tsutsumi, Yoshikazu Isomura, Masanobu Kano, Kazuo Kitamura

Communications Biology, 6 924, Sep 9, 2023 Peer-reviewedLast authorCorresponding author
Negative reward-prediction errors of climbing fiber inputs for cerebellar reinforcement learning algorithm

Huu Hoang, Shinichiro Tsutsumi, Masanori Matsuzaki, Masanobu Kano, Keisuke Toyama, Kazuo Kitamura, Mitsuo Kawato

biorxiv, Mar 13, 2023 Corresponding author
A multicolor suite for deciphering population coding in calcium and cAMPin vivo

Tatsushi Yokoyama, Satoshi Manita, Hiroyuki Uwamori, Mio Tajiri, Itaru Imayoshi, Sho Yagishita, Masanori Murayama, Kazuo Kitamura, Masayuki Sakamoto

biorxiv, Jan 8, 2023
In Vivo Wide-Field and Two-Photon Calcium Imaging from a Mouse using a Large Cranial Window.

Satoshi Manita, Eiji Shigetomi, Haruhiko Bito, Schuichi Koizumi, Kazuo Kitamura

Journal of visualized experiments : JoVE, (186), Aug 4, 2022 Peer-reviewedLast authorCorresponding author
A Novel Device of Reaching, Grasping, and Retrieving Task for Head-Fixed Mice

Satoshi Manita, Koji Ikezoe, Kazuo Kitamura

Frontiers in Neural Circuits, 16, May 12, 2022 Peer-reviewedLast authorCorresponding author
A Flp-dependent G-CaMP9a transgenic mouse for neuronal imaging in vivo

Masayuki Sakamoto, Masatoshi Inoue, Atsuya Takeuchi, Shigetaka Kobari, Tatsushi Yokoyama, Shin-ichiro Horigane, Sayaka Takemoto-Kimura, Manabu Abe, Kenji Sakimura, Masanobu Kano …

Cell Reports Methods, 100168-100168, Feb, 2022 Peer-reviewed
A database and deep learning toolbox for noise-optimized, generalized spike inference from calcium imaging

Peter Rupprecht, Stefano Carta, Adrian Hoffmann, Mayumi Echizen, Antonin Blot, Alex C. Kwan, Yang Dan, Sonja B. Hofer, Kazuo Kitamura, Fritjof Helmchen …

Nature Neuroscience, 24(9) 1324-1337, Sep, 2021 Peer-reviewed
Improved hyperacuity estimation of spike timing from calcium imaging

Huu Hoang, Masa-aki Sato, Shigeru Shinomoto, Shinichiro Tsutsumi, Miki Hashizume, Tomoe Ishikawa, Masanobu Kano, Yuji Ikegaya, Kazuo Kitamura, Mitsuo Kawato …

Scientific Reports, 10(1) 17844-17844, Dec, 2020 Peer-reviewed
Activation of the reward system ameliorates passive cutaneous anaphylactic reaction in mice

Shotaro Nakajima, Satoshi Manita, Guannan Yu, Kayoko Ishimaru, Koji Kono, Kazuo Kitamura, Atsuhito Nakao

Allergy, Jun 29, 2020 Peer-reviewed
Modular organization of cerebellar climbing fiber inputs during goal-directed behavior

Shinichiro Tsutsumi, Naoki Hidaka, Yoshikazu Isomura, Masanori Matsuzaki, Kenji Sakimura, Masanobu Kano, Kazuo Kitamura

eLife, 8 e47021, Oct 9, 2019 Peer-reviewedLast authorCorresponding author
Rational Engineering of XCaMPs, a Multicolor GECI Suite for In Vivo Imaging of Complex Brain Circuit Dynamics.

Masatoshi Inoue, Atsuya Takeuchi, Satoshi Manita, Shin-Ichiro Horigane, Masayuki Sakamoto, Ryosuke Kawakami, Kazushi Yamaguchi, Kouhei Otomo, Hiroyuki Yokoyama, Ryang Kim …

Cell, 177(5) 1346-1360, May 16, 2019 Peer-reviewed
mGluR1 in cerebellar Purkinje cells is essential for the formation but not expression of associative eyeblink memory.

Harumi Nakao, Yasushi Kishimoto, Kouichi Hashimoto, Kazuo Kitamura, Miwako Yamasaki, Kazuki Nakao, Masahiko Watanabe, Masanobu Kano, Yutaka Kirino, Atsu Aiba

Scientific reports, 9(1) 7353-7353, May 14, 2019 Peer-reviewed
Patchwork-Type Spontaneous Activity in Neonatal Barrel Cortex Layer 4 Transmitted via Thalamocortical Projections

Hidenobu Mizuno, Koji Ikezoe, Shingo Nakazawa, Takuya Sato, Kazuo Kitamura, Takuji Iwasato

Cell Reports, 22(1) 123-135, Jan 2, 2018 Peer-reviewed
Maturation of Cerebellar Purkinje Cell Population Activity during Postnatal Refinement of Climbing Fiber Network

Jean-Marc Good, Michael Mahoney, Taisuke Miyazaki, Kenji F. Tanaka, Kenji Sakimura, Masahiko Watanabe, Kazuo Kitamura, Masanobu Kano

CELL REPORTS, 21(8) 2066-2073, Nov, 2017 Peer-reviewed
Serotonin rebalances cortical tuning and behavior linked to autism symptoms in 15q11-13 CNV mice

Nobuhiro Nakai, Masatoshi Nagano, Fumihito Saitow, Yasuhito Watanabe, Yoshinobu Kawamura, Akiko Kawamoto, Kota Tamada, Hiroshi Mizuma, Hirotaka Onoe, Yasuyoshi Watanabe …

SCIENCE ADVANCES, 3(6) e1603001, Jun, 2017 Peer-reviewed
Dendritic Spikes in Sensory Perception

Satoshi Manita, Hiroyoshi Miyakawa, Kazuo Kitamura, Masanori Murayama

FRONTIERS IN CELLULAR NEUROSCIENCE, 11 29, Feb, 2017 Peer-reviewed
Rational design of a high-affinity, fast, red calcium indicator R-CaMP2

Masatoshi Inoue, Atsuya Takeuchi, Shin-ichiro Horigane, Masamichi Ohkura, Keiko Gengyo-Ando, Hajime Fujii, Satoshi Kamijo, Sayaka Takemoto-Kimura, Masanobu Kano, Junichi Nakai …

NATURE METHODS, 12(1) 64-70, Jan, 2015 Peer-reviewedCorresponding author
Structure-Function Relationships between Aldolase C/Zebrin II Expression and Complex Spike Synchrony in the Cerebellum

Shinichiro Tsutsumi, Maya Yamazaki, Taisuke Miyazaki, Masahiko Watanabe, Kenji Sakimura, Masanobu Kano, Kazuo Kitamura

JOURNAL OF NEUROSCIENCE, 35(2) 843-852, Jan, 2015 Peer-reviewedLast authorCorresponding author

Misc.

Cerebellar climbing fibers convey behavioral information of multiplex modalities and form functional modules

Koji Ikezoe, Naoki Hidaka, Satoshi Manita, Masayoshi Murakami, Shinichiro Tsutsumi, Yoshikazu Isomura, Masanobu Kano, Kazuo Kitamura

bioRxiv, (preprint), Aug 25, 2022
Rational design of a high-affinity, fast, red calcium indicator R-CaMP2 (vol 12, pg 64, 2015)

Masatoshi Inoue, Atsuya Takeuchi, Shin-ichiro Horigane, Masamichi Ohkura, Keiko Gengyo-Ando, Hajime Fujii, Satoshi Kamijo, Sayaka Takemoto-Kimura, Masanobu Kano, Junichi Nakai …

NATURE METHODS, 12(9) 893-893, Sep, 2015
Rational design of a high-affinity, fast, red calcium indicator R-CaMP2

Masatoshi Inoue, Atsuya Takeuchi, Shin-ichiro Horigane, Masamichi Ohkura, Keiko Gengyo-Ando, Hajime Fujii, Satoshi Kamijo, Sayaka Takemoto-Kimura, Masanobu Kano, Junichi Nakai …

JOURNAL OF PHARMACOLOGICAL SCIENCES, 128(3) S92-S92, Jul, 2015
in vivo イメージング

喜多村和郎

脳神経科学イラストレイテッド, Mar, 2013 Invited
Relationship between the synchrony of climbing fiber activities and the aldolase C compartments in mouse cerebellar cortex

Shinichiro Tsutsumi, Mayumi Tada, Kenji Sakimura, Kazuo Kitamura, Masanobu Kano

JOURNAL OF PHYSIOLOGICAL SCIENCES, 63 S128-S128, 2013
Climbing fiber network refinement and desynchronization of Purkinje cell population activity during postnatal cerebellar development

Jean-Marc Good, Kazuo Kitamura, Kenji Sakimura, Masanobu Kano

JOURNAL OF PHYSIOLOGICAL SCIENCES, 63 S242-S242, 2013
The relationship between local structure of orientation map and orientation selectivity of neurons in monkey V1 examined by 2-photon calcium imaging techniques

2012(11) 1-6, Jun 21, 2012
The relationship between local structure of orientation map and orientation selectivity of neurons in monkey V1 examined by 2-photon calcium imaging techniques

IKEZOE Koji, MORI Yoshiya, KITAMURA Kazuo, TAMURA Hiroshi, FUJITA Ichiro

IEICE technical report. Neurocomputing, 112(108) 59-64, Jun 21, 2012
Two-photon targeted patch-clamp recordings in vivo

kazuo kitamura

Patch Clamp Techniques, Apr, 2012 Invited
in vivo two-photon imaging of dendritic activity of cerebellar Purkinje cell

Kazuo Kitamura, Kouichi Hashimoto, Masanobu Kano

Seitai no Kagaku, 63(1) 26-33, Feb, 2012 Invited
マウス一次視覚野の受容野構造地図の可視化:2光子カルシウムイメージングを用いた逆相関法

森理也, 池添貢司, 古高潤一, 喜多村和郎, 田村弘, 藤田一郎

日本生理学雑誌, 73(6) 179-179, Jun 1, 2011
In vivo イメージングパッチクランプ法

喜多村和郎

最新パッチクランプ実験技術法（岡田泰伸編）, May, 2011 Invited
Enhanced synchrony of climbing fiber-induced Ca2+ signaling in cerebellar Purkinje cells in GluD2 (GluR delta 2) knockout mouse

Miki Hashizume, Kazuo Kitamura, Kenji Sakimura, Masanobu Kano

NEUROSCIENCE RESEARCH, 71 E247-E247, 2011
Postsynaptic P/Q type voltage-dependent Ca2+ channel is involved in refinement of cerebellar climbing fiber to Purkinje cell synapses in early postnatal development

Kouichi Hashimoto, Mika Tsujita, Taisuke Miyazaki, Kazuo Kitamura, Maya Yamazaki, Shin Hee-sup, Masahiko Watanabe, Kenji Sakimura, Masanobu Kano

NEUROSCIENCE RESEARCH, 71 E322-E322, 2011
P2-u14 In vivo two-photon uncaging of glutamate revealing the structure-function relationships of dendritic spines in the neocortex of adult mice

Jun Noguchi, Akira Nagaoka, Satoshi Watanabe, Graham C. R. Ellis-Davies, Kazuo Kitamura, Masanobu Kano, Masanori Matsuzaki, Haruo Kasai

NEUROSCIENCE RESEARCH, 71 E206-E206, 2011
Desynchronization of cerebellar Purkinje cell population activity during postnatal development

Jean-Marc Good, Kazuo Kitamura, Masanobu Kano

NEUROSCIENCE RESEARCH, 71 E60-E60, 2011
小脳回路発達と可塑性の最前線登上線維の発達過程におけるP/Q型電位依存性カルシウムチャネルの役割(Cellebellar circuitry: Cutting-edge of development and plasticity P/Q type voltage dependent Ca2+ channel is crucial for early postnatal development of climbing fiber to Purkinje cell synapse)

橋本浩一, 辻田実加, 喜多村和郎, 宮崎太輔, 山崎真弥, Shin Hee-Sup, 渡辺雅彦, 崎村建司, 狩野方伸

神経化学, 49(2-3) 461-461, Aug, 2010
Two-photon imaging of population activity from cerebellar Purkinje cells in GluD2(GluR delta 2) knockout mouse

Miki Hashizume, Kazuo Kitamura, Kenji Sakimura, Masanobu Kano

NEUROSCIENCE RESEARCH, 68 E64-E64, 2010
P/Q type voltage-dependent Ca2+ channel is required for refinement of climbing fiber to Purkinje cell synapse in early postnatal development

Kouichi Hashimoto, Mika Tsujita, Taisuke Miyazaki, Maya Yamazaki, Kazuo Kitamura, Hee-sup Shin, Masahiko Watanabe, Kenji Sakimura, Masanobu Kano

JOURNAL OF PHYSIOLOGICAL SCIENCES, 60 S83-S83, 2010
2光子イメージングを用いた個体脳単一ニューロンからの選択的記録法．

喜多村和郎

脳21, 12(3) 70-76, Jul, 2009 Invited

Professional Memberships

Research Projects

行動変容を創発する脳ダイナミクスの解読と操作が拓く多元生物学

科学研究費助成事業, 学術変革領域研究(A), 日本学術振興会, Jun, 2022 - Mar, 2027

松崎政紀, 尾藤晴彦, 田中康裕, 春野雅彦, 喜多村和郎, 中江健, 井上謙一
行動変容の表出を規定する運動回路動態の解明

科学研究費助成事業学術変革領域研究(A), 学術変革領域研究(A), 日本学術振興会, Jun, 2022 - Mar, 2027

喜多村和郎
小脳機能ゾーンの生理学的意義の解明

科学研究費助成事業基盤研究(A), 基盤研究(A), 日本学術振興会, Apr, 2022 - Mar, 2026

喜多村和郎
ニューロン-グリア相互作用からなる超神経場の直接可視化による脳情報の解読

科学研究費助成事業, 挑戦的研究(萌芽), 日本学術振興会, Jun, 2023 - Mar, 2025
Brain information dynamics underlying multi-area interconnectivity and parallel processing

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2017 - Mar, 2022
Optical Measurement and Control of Multiareal Brain Information Dynamics in Cognition and Movement

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2017 - Mar, 2022

KITAMURA Kazuo
Modular organization of cerebellar cortex during voluntary movements

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

KITAMURA Kazuo
運動適応における大脳小脳連関の回路シフト解明と操作

科学研究費助成事業新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2017 - Mar, 2018

喜多村和郎
精神病態脳における大規模2光子解析法の開発

科学研究費助成事業新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2015 - Mar, 2017

喜多村和郎
運動制御・運動記憶における大脳ー小脳動的連関の解明とその操作

科学研究費助成事業新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2015 - Mar, 2017

喜多村和郎
Representation of motor learning and motor timing in the cerebellum

Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2017

KITAMURA Kazuo
Population coding of individual synaptic inputs

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2013 - 2015

KITAMURA Kazuo
Optical mapping of cerbrocerebellar communication loop

Grants-in-Aid for Scientific Research, Grant-in-Aid for Challenging Exploratory Research, Japan Society for the Promotion of Science, 2013 - 2014

KITAMURA Kazuo
運動制御における小脳小規模回路の機能

科学研究費補助金(新学術領域研究(研究領域提案型)), 新学術領域研究(研究領域提案型), 文部科学省, 2013 - 2014

喜多村和郎
生体内で単一シナプス活動を可視化する技術の開発と最適化

科学研究費補助金(新学術領域研究(研究領域提案型)), 新学術領域研究(研究領域提案型), 文部科学省, 2013 - 2014

喜多村和郎
小脳皮質小規模回路の作動原理とその生理的意義

科学研究費補助金(新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型)), 新学術領域研究(研究領域提案型), 新学術領域研究(研究領域提案型), 文部科学省, 2011 - 2012

喜多村和郎
Activities of cerebellar neurons in behaving mice

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (A), Japan Society for the Promotion of Science, 2010 - 2012

KITAMURA Kazuo
Spatial-temporal structure of synaptic inputs-large-scale spine imaging study-

Grants-in-Aid for Scientific Research, Grant-in-Aid for Research Activity Start-up, Japan Society for the Promotion of Science, 2011 - 2011

TAKAHASHI Naoya, KITAMURA Kazuo, MATSUO Naoki, KANO Masanobu, MATSUKI Norio, IKEGAYA Yuji
In vivo imaging of sensory synaptic inputs in neocortex

Grants-in-Aid for Scientific Research(挑戦的萌芽研究), 挑戦的萌芽研究, Ministry of Education, Culture, Sports, Science and Technology, 2010 - 2011

Kazuo KITAMURA
個体内単一ニューロン選択的遺伝子改変による機能解析法の開発

科学研究費補助金(萌芽研究, 挑戦的萌芽研究), 萌芽研究, 挑戦的萌芽研究, 文部科学省, 2008 - 2009

喜多村和郎

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Education

Research History

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Papers

Misc.

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