松澤洋 (Hiroshi Matsuzawa) - マイポータル - researchmap

基本情報

所属: 旧所属青森大学薬学部薬学科薬学部教授,工学部長

学位: 農学博士(東京大学)
農学修士(東京大学)

J-GLOBAL ID: 200901098262094470
researchmap会員ID: 1000012987

研究キーワード

2

研究分野

1

ライフサイエンス / 応用生物化学 /

経歴

6

1994年 - 1999年

東京大学教授
1994年 - 1999年

東京大学
1985年 - 1994年

東京大学助教授
1985年 - 1994年

東京大学
1969年 - 1985年

東京大学助手
1969年 - 1985年

The University of Tokyo, Research Assistant

学歴

4

委員歴

3

受賞

2

1999年

日本農芸化学会功績賞
1989年

チバ・ガイギー科学振興財団

MISC

77

An engineered disulfide bond between residues 69 and 238 in extended-spectrum beta-lactamase Toho-1 reduces its activity toward third-generation cephalosporins

A Shimizu-Ibuka, H Matsuzawa, H Sakai

BIOCHEMISTRY 43(50) 15737-15745 2004年12月
Crystal structure of a family 54 alpha-L-arabinofuranosidase reveals a novel carbohydrate-binding module that can bind arabinose

A Miyanaga, T Koseki, H Matsuzawa, T Wakagi, H Shoun, S Fushinobu

JOURNAL OF BIOLOGICAL CHEMISTRY 279(43) 44907-44914 2004年10月
Crystal structure of a family 54 alpha-L-arabinofuranosidase reveals a novel carbohydrate-binding module that can bind arabinose

A Miyanaga, T Koseki, H Matsuzawa, T Wakagi, H Shoun, S Fushinobu

JOURNAL OF BIOLOGICAL CHEMISTRY 279(43) 44907-44914 2004年10月
Expression, purification, crystallization and preliminary X-ray analysis of alpha-L-arabinofuranosidase B from Aspergillus kawachii

A Miyanaga, T Koseki, H Matsuzawa, T Wakagi, H Shoun, S Fushinobu

ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY 60 1286-1288 2004年7月
タンパク質工学の基礎

東京化学同人 2004年
Crystal structure of extended-spectrum beta-lactamase Toho-1: Insights into the molecular mechanism for catalytic reaction and substrate specificity expansion

AS Ibuka, Y Ishii, M Galleni, M Ishiguro, K Yamaguchi, JM Frere, H Matsuzawa, H Sakai

BIOCHEMISTRY 42(36) 10634-10643 2003年9月
Crystal structure of extended-spectrum beta-lactamase Toho-1: Insights into the molecular mechanism for catalytic reaction and substrate specificity expansion

AS Ibuka, Y Ishii, M Galleni, M Ishiguro, K Yamaguchi, JM Frere, H Matsuzawa, H Sakai

BIOCHEMISTRY 42(36) 10634-10643 2003年9月
Crystal structures of 4-alpha-glucanotransferase from Thermococcus litoralis and its complex with an inhibitor

H Imamura, S Fushinobu, M Yamamoto, T Kumasaka, BS Jeon, T Wakagi, H Matsuzawa

JOURNAL OF BIOLOGICAL CHEMISTRY 278(21) 19378-19386 2003年5月
Crystal structures of 4-alpha-glucanotransferase from Thermococcus litoralis and its complex with an inhibitor

H Imamura, S Fushinobu, M Yamamoto, T Kumasaka, BS Jeon, T Wakagi, H Matsuzawa

JOURNAL OF BIOLOGICAL CHEMISTRY 278(21) 19378-19386 2003年5月
Role of two α-L-arabinofuranosidases in arabinoxylan degradation and characteristics of the encoding genes from shochu koji molds, Aspergillus Kawachii and Aspergillus awamori

Journal of Bioscience and Bioengineering 96(3), 232-241 2003年
Acyl-intermediate structures of the extended-spectrum class A beta-lactamase, Toho-1, in complex with cefotaxime, cephalothin, and benzylpenicillin

T Shimamura, A Ibuka, S Fushinobu, T Wakagi, M Ishiguro, Y Ishii, H Matsuzawa

JOURNAL OF BIOLOGICAL CHEMISTRY 277(48) 46601-46608 2002年11月
Acyl-intermediate structures of the extended-spectrum class A beta-lactamase, Toho-1, in complex with cefotaxime, cephalothin, and benzylpenicillin

T Shimamura, A Ibuka, S Fushinobu, T Wakagi, M Ishiguro, Y Ishii, H Matsuzawa

JOURNAL OF BIOLOGICAL CHEMISTRY 277(48) 46601-46608 2002年11月
Trimeric crystal structure of the glycoside hydrolase family 42 beta-galactosidase from Thermus thermophilus A4 and the structure of its complex with galactose

M Hidaka, S Fushinobu, N Ohtsu, H Motoshima, H Matsuzawa, H Shoun, T Wakagi

JOURNAL OF MOLECULAR BIOLOGY 322(1) 79-91 2002年9月
Crystal structure of non-allosteric L-lactate dehydrogenase from Lactobacillus pentosus at 2.3 Å resolution: Specific interactions at subunit interfaces

Hiroyuki Uchikoba, Shinya Fushinobu, Takayoshi Wakagi, Michiko Konno, Hayao Taguchi, Hiroshi Matsuzawa

Proteins: Structure, Function and Genetics 46(2) 206-214 2002年2月1日
Crystal structure of non-allosteric L-lactate dehydrogenase from Lactobacillus pentosus at 2.3 Å resolution: Specific interactions at subunit interfaces

Hiroyuki Uchikoba, Shinya Fushinobu, Takayoshi Wakagi, Michiko Konno, Hayao Taguchi, Hiroshi Matsuzawa

Proteins: Structure, Function and Genetics 46(2) 206-214 2002年2月1日
Trimeric Crystal Structre of the Glycoside Hydrolase Family 42 beta-Galactosidase from Thermus thermophilus A4 and the Structure of its Complex with Galactose

Jouranal of Molecular Biology 322, 79-91 2002年
Sodium-23 and Lanthanum-139 Nuclear Magnetic Resonance Studies of Cation Binding to Aqualysin I, a Thermostable Serine Protease.

Bioscience, Biotechnology, and Biochemistry 66(6), 1281-1286 2002年
Zinc-Coodination of Aspartic Acid-76 in Suifolobus Ferredoxin is not Required for Thermal Stability of the Molecule.

Journal of Inorganic Biochemistry 89, 69-73 2002年
An Absolute Requirement of Fructose 1,6-Bisphosphate for the Lactobacillus Casei L-lactate Dehydrogenase Activity Induced by a Single Amino Acid Substitution.

Protein Engineering 15(1), 35-41 2002年
An Absolute Requirement of Fructose 1,6-Bisphosphate for the Lactobacillus Casei L-lactate Dehydrogenase Activity Induced by a Single Amino Acid Substitution.

Protein Engineering 15(1), 35-41 2002年

もっとみる

書籍等出版物

5

Handbook of Proteolytic Enzymes

Elsevier Academic Press 2004年
Intramolecular Chaperones and Protein Folding(jointly worked)

R. G. Landes Company 1995年
Stabilization of Proteases by an Engineered Disulfide Bond

Kodansha, "Molecular Aspects of Enzyme Catalysis" 1994年
Analyses of enzyme functions by gene engineering

1993年
Penicillin-binding proteins

1993年

所属学協会

5

共同研究・競争的資金等の研究課題

2