塩坂貞夫 (Sadao Shiosaka) - マイポータル

基本情報

学位: 医学博士(大阪大学)
M.Sc.

J-GLOBAL ID: 200901046448918015
researchmap会員ID: 1000165738

研究キーワード

研究分野

ライフサイエンス / 神経科学一般 /

学歴

委員歴

論文

Functional brain fluorescence plurimetry in rat by implantable concatenated CMOS imaging system

Takuma Kobayashi, Hiroyuki Masuda, Chikara Kitsumoto, Makito Haruta, Mayumi Motoyama, Yasumi Ohta, Toshihiko Noda, Kiyotaka Sasagawa, Takashi Tokuda, Sadao Shiosaka …

BIOSENSORS & BIOELECTRONICS 53 31-36 2014年3月査読有り
Does extracellular proteolysis control mammalian cognition?

Hideki Tamura, Yasuyuki Ishikawa, Sadao Shiosaka

Reviews in the Neurosciences 24(4) 365-374 2013年8月査読有り
Impaired synaptic clustering of postsynaptic density proteins and altered signal transmission in hippocampal neurons, and disrupted learning behavior in PDZ1 and PDZ2 ligand binding-deficient PSD-95 knockin mice

Hitoshi Nagura, Yasuyuki Ishikawa, Katsunori Kobayashi, Keizo Takao, Tomo Tanaka, Kouki Nishikawa, Hideki Tamura, Sadao Shiosaka, Hidenori Suzuki, Tsuyoshi Miyakawa …

MOLECULAR BRAIN 5 43 2012年12月査読有り
Novel implantable imaging system for enabling simultaneous multiplanar and multipoint analysis for fluorescence potentiometry in the visual cortex

Takuma Kobayashi, Mayumi Motoyama, Hiroyuki Masuda, Yasumi Ohta, Makito Haruta, Toshihiko Noda, Kiyotaka Sasagawa, Takashi Tokuda, Hideki Tamura, Yasuyuki Ishikawa …

BIOSENSORS & BIOELECTRONICS 38(1) 321-330 2012年10月査読有り
Processing of Neuregulin-1 by Neuropsin Regulates GABAergic Neuron to Control Neural Plasticity of the Mouse Hippocampus

Hideki Tamura, Miho Kawata, Seiya Hamaguchi, Yasuyuki Ishikawa, Sadao Shiosaka

JOURNAL OF NEUROSCIENCE 32(37) 12657-12672 2012年9月査読有り
NGF-p75 and neuropsin/KLK8 pathways stimulate each other to cause hyperkeratosis and acanthosis in inflamed skin

Kenta Shingaki, Manabu Taniguchi, Shigeyuki Kanazawa, Shinsuke Matsuzaki, Tameyasu Maeda, Shingo Miyata, Tateki Kubo, Kosuke Torii, Sadao Shiosaka, Masaya Tohyama

JOURNAL OF DERMATOLOGICAL SCIENCE 67(1) 71-73 2012年7月査読有り
CMOS image sensor integrated with micro-LED and multielectrode arrays for the patterned photostimulation and multichannel recording of neuronal tissue

Arata Nakajima, Hiroshi Kimura, Yosmongkol Sawadsaringkarn, Yasuyo Maezawa, Takuma Kobayashi, Toshihiko Noda, Kiyotaka Sasagawa, Takashi Tokuda, Yasuyuki Ishikawa, Sadao Shiosaka …

OPTICS EXPRESS 20(6) 6097-6108 2012年3月査読有り
Neuropsin-A possible modulator of synaptic plasticity

Sadao Shiosaka, Yasuyuki Ishikawa

JOURNAL OF CHEMICAL NEUROANATOMY 42(1) 24-29 2011年9月査読有り
Diversity of neuropsin (KLK8)-dependent synaptic associativity in the hippocampal pyramidal neuron

Yasuyuki Ishikawa, Hideki Tamura, Sadao Shiosaka

JOURNAL OF PHYSIOLOGY-LONDON 589(14) 3559-3573 2011年7月査読有り
Neuropsin cleaves EphB2 in the amygdala to control anxiety

Benjamin K. Attwood, Julie-Myrtille Bourgognon, Satyam Patel, Mariusz Mucha, Emanuele Schiavon, Anna E. Skrzypiec, Kenneth W. Young, Sadao Shiosaka, Michal Korostynski, Marcin Piechota …

NATURE 473(7347) 372-U553 2011年5月査読有り
Olig2-expressing progenitor cells preferentially differentiate into oligodendrocytes in cuprizone-induced demyelinated lesions

Mohammad Shyful Islam, Kouko Tatsumi, Hiroaki Okuda, Sadao Shiosaka, Akio Wanaka

NEUROCHEMISTRY INTERNATIONAL 54(3-4) 192-198 2009年3月査読有り
A multimodal sensing device for fluorescence imaging and electrical potential measurement of neural activities in a mouse deep brain.

Ohta J, Tagawa A, Minami H, Noda T, Sasagawa K, Tokuda T, Hatanaka Y, Ishikawa Y, Tamura H, Shiosaka S

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 2009 5887-5890 2009年査読有り
Genetic Variations of Human Neuropsin Gene and Psychiatric Disorders: Polymorphism Screening and Possible Association with Bipolar Disorder and Cognitive Functions

Aiko Izumi, Yoshimi Iijima, Hiroko Noguchi, Tadahiro Numakawa, Takeya Okada, Hiroaki Hori, Tadafumi Kato, Masahiko Tatsumi, Asako Kosuga, Kunitoshi Kamijima …

NEUROPSYCHOPHARMACOLOGY 33(13) 3237-3245 2008年12月査読有り
One-chip sensing device (biomedical photonic LSI) enabled to assess hippocampal steep and gradual up-regulated proteolytic activities

Hideki Tamura, David C. Ng, Takashi Tokuda, Honda Noaki, Takuma Nakagawa, Taro Mizuno, Yumiko Hatanaka, Yasuyuki Ishikawa, Jun Ohta, Sadao Shiosaka

JOURNAL OF NEUROSCIENCE METHODS 173(1) 114-120 2008年8月査読有り
Acute stress increases neuropsin mRNA expression in the mouse hippocampus through the glucocorticoid pathway

Akiko Harada, Sadao Shiosaka, Yasuyuki Ishikawa, Shoji Komai

NEUROSCIENCE LETTERS 436(2) 273-277 2008年5月査読有り
Neuropsin (KLK8)-dependent and -independent synaptic tagging in the Schaffer-collateral pathway of mouse hippocampus

Yasuyuki Ishikawa, Yoichiro Horii, Hideki Tamura, Sadao Shiosaka

JOURNAL OF NEUROSCIENCE 28(4) 843-849 2008年1月査読有り
Autophagy is activated for cell survival after endoplasmic reticulum stress

Maiko Ogata, Shin-ichiro Hino, Atsushi Saito, Keisuke Morikawa, Shinichi Kondo, Soshi Kanemoto, Tomohiko Murakami, Manabu Taniguchi, Ichiro Tanii, Kazuya Yoshinaga …

MOLECULAR AND CELLULAR BIOLOGY 26(24) 9220-9231 2006年12月査読有り
Real time in vivo imaging and measurement of serine protease activity in the mouse hippocampus using a dedicated complementary metal-oxide semiconductor imaging device

David C. Ng, Hideki Tamura, Takashi Tokuda, Akio Yamamoto, Masamichi Matsuo, Masahiro Nunoshita, Yasuyuki Ishikawa, Sadao Shiosaka, Jun Ohta

JOURNAL OF NEUROSCIENCE METHODS 156(1-2) 23-30 2006年9月査読有り
Neuropsin is essential for early processes of memory acquisition and Schaffer collateral long-term potentiation in adult mouse hippocampus in vivo

H Tamura, Y Ishikawa, N Hino, M Maeda, S Yoshida, S Kaku, S Shiosaka

JOURNAL OF PHYSIOLOGY-LONDON 570(3) 541-551 2006年2月査読有り
A new neural imaging approach using a CMOS imaging device.

Ng DC, Tokuda T, Nakagawa T, Tamura H, Nunoshita M, Ishikawa Y, Shiosaka S, Ohta J

Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual Conference 1 1061-1064 2006年査読有り

もっとみる

MISC

Genetic Variations of Human Neuropsin Gene and Psychiatric Disorders: Polymorphism Screening and Possible Association with Bipolar Disorder and Cognitive Functions

Aiko Izumi, Yoshimi Iijima, Hiroko Noguchi, Tadahiro Numakawa, Takeya Okada, Hiroaki Hori, Tadafumi Kato, Masahiko Tatsumi, Asako Kosuga, Kunitoshi Kamijima …

NEUROPSYCHOPHARMACOLOGY 33(13) 3237-3245 2008年12月
One-chip sensing device (biomedical photonic LSI) enabled to assess hippocampal steep and gradual up-regulated proteolytic activities

Hideki Tamura, David C. Ng, Takashi Tokuda, Honda Noaki, Takuma Nakagawa, Taro Mizuno, Yumiko Hatanaka, Yasuyuki Ishikawa, Jun Ohta, Sadao Shiosaka

JOURNAL OF NEUROSCIENCE METHODS 173(1) 114-120 2008年8月
Increased anxiety-like behavior in neuropsin (kallikrein-related peptidase 8) gene-deficient mice

Yoichiro Horii, Tsuyoshi Miyakawa, Nobuyuki Yamasaki, Sadao Shiosaka

BEHAVIORAL NEUROSCIENCE 122(3) 498-504 2008年6月
Neuropsin (KLK8)-dependent and -independent synaptic tagging in the Schaffer-collateral pathway of mouse hippocampus

Yasuyuki Ishikawa, Yoichiro Horii, Hideki Tamura, Sadao Shiosaka

JOURNAL OF NEUROSCIENCE 28(4) 843-849 2008年1月
Neuropsin is essential for early processes of memory acquisition and Schaffer collateral long-term potentiation in adult mouse hippocampus in vivo

H Tamura, Y Ishikawa, N Hino, M Maeda, S Yoshida, S Kaku, S Shiosaka

JOURNAL OF PHYSIOLOGY-LONDON 570(3) 541-551 2006年2月
Hippocampal CA1 synaptic plasticity as a gamma transfer function

Tamura, H. Ikegaya, Y. Shiosaka, S

Neuroscience 138(4) 1049-1053 2006年
Role of neuropsin in formation and maturation of Schaffer-collateral L1cam-immunoreactive synaptic boutons

Nakamura, Y. Tamura, H. Horinouchi, K. Shiosaka, S

J Cell Sci 119(7) 1341-1349 2006年
Distribution of L1cam mRNA in the adult mouse brain: In situ hybridization and northern blot analyses

K Horinouchi, Y Nakamura, H Yamanaka, T Watabe, S Shiosaka

JOURNAL OF COMPARATIVE NEUROLOGY 482(4) 386-404 2005年2月
Serine proteases regulating synaptic plasticity

Sadao Shiosaka

Anat Sci Int （日本解剖学会） 79 137 2004年
Serine proteases regulating synaptic plasticity

Anat Sci Int （日本解剖学会） 79, 137 2004年
NMDA-dependent proteolysis of presynaptic adhesion molecule L1 in the hippocampus by neuropsin

K Matsumoto-Miyai, A Ninomiya, H Yamasaki, H Tamura, Y Nakamura, S Shiosaka

JOURNAL OF NEUROSCIENCE 23(21) 7727-7736 2003年8月
Distribution and densitometry mapping of LI-CAM immunoreactivity in the adult mouse brain - Light microscopic observation

Hana Munakata, Yukiko Nakamura, Kazumasa Matsumoto-Miyai, Kouichi Itoh, Hironobu Yamasaki, Sadao Shiosaka

BMC Neuroscience 4 2003年4月16日
Characterization of recombinant and brain neuropsin, a plasticity-related serine protease.

SHIMIZU C, YOSHIDA S, SHIBATA M, KATO K, SHIOSAKA T, MIDORIKAWA R, KAMACHI T, KAWABE A, SHIOSAKA S

J Biol Chem, 273(18) 11189-11196 1998年
Expression and activity-dependent changes of a novel limbic-serine protease gene in the hippocampus

Chen ZL, Yoshida S, Kato K, Momota Y, Suzuki J, Tanaka T, Ito J, Nishino H, Aimoto S, Kiyama H …

J Neurosci 15(7) 5088 1995年

書籍等出版物

動くシナプスと神経ネットワーク

金芳堂 2003年

所属学協会

共同研究・競争的資金等の研究課題

自由行動動物脳研究のためのメディカルフォトニックLSI

ＪＳＴ戦略的創造研究推進制度（研究チーム型）（戦略的基礎研究推進事業：ＣＲＥＳＴ）
短期記憶から長期記憶への変換過程

ライフサイエンス基礎科学研究
細胞接着分子－ニューロプロテアーゼ
記憶・学習
Memory and learning
Brain Protease

塩坂貞夫

基本情報

研究キーワード

研究分野

学歴

委員歴

論文

MISC

書籍等出版物

所属学協会

共同研究・競争的資金等の研究課題

産業財産権

メニュー