Toshio Kaneda

Profile Information

Affiliation: Hoshi University

Degree: (BLANK)(Osaka University)
(BLANK)(Hokkaido University)

J-GLOBAL ID: 200901084571530802
researchmap Member ID: 1000368744

Research Interests

Research Areas

Research History

Oct, 2014 - Present

准教授

Papers

Ceramicines U-Z from Chisocheton ceramicus and structure-antimalarial activity relationship study.

Alfarius Eko Nugroho, Tomoyuki Komuro, Takuya Kawaguchi, Yusuke Shindo, Chin Piow Wong, Yusuke Hirasawa, Toshio Kaneda, Takahiro Tougan, Toshihiro Horii, A Hamid A Hadi …

Journal of natural medicines, Sep 10, 2023 Peer-reviewed
Isovincathicine from Catharanthus roseus induces apoptosis in A549 cells

Mizuki Hiroki, Aishanjiang Abulikemu, Chihiro Totsuka, Yusuke Hirasawa, Toshio Kaneda, Hiroshi Morita

Journal of Natural Medicines, Sep 5, 2023 Peer-reviewed
Antimalarial ceramicines Q-T from Chisocheton ceramicus

Alfarius Eko Nugroho, Chin Piow Wong, Yusuke Hirasawa, Toshio Kaneda, Takahiro Tougan, Toshihiro Horii, A. Hamid A. Hadi, Hiroshi Morita

Journal of Natural Medicines, 77(3) 596-603, Jun, 2023 Peer-reviewed
Calofolic Acid-A from Calophyllum scriblitifolium Bark Has Vasorelaxant Activity via Indirect PKA Activation Caused by PI-3 Kinase Inhibition in Rat Vascular Smooth Muscle Cells.

Toshio Kaneda, Farida Ifadotunnikmah, Alfarius Eko Nugroho, Sae Koshikawa, Sasaki Tadahiro, Yusuke Hirasawa, Hiroshi Morita

Journal of natural products, 85(9) 2192-2198, Sep 23, 2022 Peer-reviewedLead author
Caloforines A-G, coumarins from the bark of Calophyllum scriblitifolium.

Ai Ogasawara, Ryo Noguchi, Takuya Shigi, Alfarius Eko Nugroho, Yusuke Hirasawa, Toshio Kaneda, Takahiro Tougan, Toshihiro Horii, A Hamid A Hadi, Hiroshi Morita

Journal of natural medicines, 76(3) 645-653, Mar 22, 2022 Peer-reviewed
A Novel Trimeric Triterpene From Chisocheton ceramicusMiq.

Alfarius Eko Nugroho, Marika Okabe, Yusuke Hirasawa, Chin Piow Wong, Toshio Kaneda, Takahiro Tougan, Toshihiro Horii, Hiroshi Morita

Natural Product Communications, 16(11) 1934578X2110532-1934578X2110532, Nov, 2021 Peer-reviewed
Cliniatines A-C, new Amaryllidaceae alkaloids from Clivia miniata, inhibiting Acetylcholinesterase.

Yusuke Hirasawa, Tomoko Tanaka, Shiro Hirasawa, Chin Piow Wong, Nahoko Uchiyama, Toshio Kaneda, Yukihiro Goda, Hiroshi Morita

Journal of natural medicines, Sep 22, 2021 Peer-reviewed
Walsogynes H-O from Walsura chrysogyne.

Alfarius Eko Nugroho, Saori Nakajima, Chin Piow Wong, Yusuke Hirasawa, Toshio Kaneda, Osamu Shirota, Takahiro Tougan, Toshihiro Horii, A Hamid A Hadi, Hiroshi Morita

Journal of natural medicines, 76(1) 94-101, Aug 5, 2021 Peer-reviewed
Two new bisindole alkaloids from Tabernaemontana macrocarpa Jack.

Puteri Amelia, Alfarius Eko Nugroho, Yusuke Hirasawa, Toshio Kaneda, Takahiro Tougan, Toshihiro Horii, Hiroshi Morita

Journal of natural medicines, 75(3) 633-642, Jun, 2021 Peer-reviewed
Bisindole alkaloids from Voacanga grandifolia leaves.

Alfarius Eko Nugroho, Yurika Ono, Eunji Jin, Yusuke Hirasawa, Toshio Kaneda, Abdul Rahman, Idha Kusumawati, Takahiro Tougan, Toshihiro Horii, Noor Cholies Zaini …

Journal of natural medicines, 75(2) 408-414, Mar, 2021 Peer-reviewed
Triterpenoids from Walsura trichostemon.

Alfarius Eko Nugroho, Yusuke Hirasawa, Toshio Kaneda, Osamu Shirota, Michiyo Matsuno, Hajime Mizukami, Hiroshi Morita

Journal of natural medicines, 75(2) 415-422, Mar, 2021 Peer-reviewed
Cytotoxic Activity and Molecular Docking of Indole Alkaloid Voacangine, Bis-indole Alkaloids Vobtusine, and Vobtusine Lactone from the Indonesian Plant: Voacanga foetida (Blume) Rolfe

Adriani Susanty, Dachriyanus, Yanwirasti, Fatma Sri Wahyuni, Puteri Amelia, Frengki, Ihsan Ikhtiarudin, Yusuke Hirasawa, Toshio Kaneda, Hiroshi Morita

INDONESIAN JOURNAL OF PHARMACY, 32(4) 442-453, 2021 Peer-reviewed
Correction to: Cycloartane triterpenoid (23R, 24E)-23-acetoxymangiferonic acid inhibited proliferation and migration in B16-F10 melanoma via MITF downregulation caused by inhibition of both β-catenin and c-Raf-MEK1-ERK signaling axis.

Toshio Kaneda, Misaki Matsumoto, Yayoi Sotozono, Satoshi Fukami, Alfarius Eko Nugroho, Yusuke Hirasawa, Hadi A Hamid A, Hiroshi Morita

Journal of natural medicines, 74(3) 612-612, Jun, 2020 Peer-reviewed
Anti-tumor Effects of Cyclolinopeptide on Giant-cell Tumor of the Bone.

Yuta Taniguchi, Norio Yamamoto, Katsuhiro Hayashi, Akihiko Takeuchi, Shinji Miwa, Kentaro Igarashi, Takashi Higuchi, Kensaku Abe, Hirotaka Yonezawa, Yoshihiro Araki …

Anticancer research, 39(11) 6145-6153, Nov, 2019 Peer-reviewed
Two new sarpagine-type indole alkaloids and antimalarial activity of 16-demethoxycarbonylvoacamine from Tabernaemontana macrocarpa Jack.

Puteri Amelia, Alfarius Eko Nugroho, Yusuke Hirasawa, Toshio Kaneda, Takahiro Tougan, Toshihiro Horii, Hiroshi Morita

Journal of natural medicines, 73(4) 820-825, Sep, 2019 Peer-reviewed
Cyclolinopeptide F, a cyclic peptide from flaxseed inhibited RANKL-induced osteoclastogenesis via downergulation of RANK expression.

Toshio Kaneda, Yuki Nakajima, Sae Koshikawa, Alfarius Eko Nugroho, Hiroshi Morita

Journal of natural medicines, 73(3) 504-512, Jun, 2019 Peer-reviewed
Correction to: Ceramicines M-P from Chisocheton ceramicus: isolation and structure-activity relationship study.

Alfarius Eko Nugroho, Akiyo Hashimoto, Chin-Piow Wong, Hiromasa Yokoe, Masayoshi Tsubuki, Toshio Kaneda, A Hamid A Hadi, Hiroshi Morita

Journal of natural medicines, 73(3) 682-682, Jun, 2019 Peer-reviewed
New vasorelaxant indole alkaloids, taberniacins A and B, from Tabernaemontana divaricata.

Hirasawa Y, Dai X, Deguchi J, Hatano S, Sasaki T, Ohtsuka R, Nugroho AE, Kaneda T, Morita H

Journal of natural medicines, 73(3) 627-632, Jun, 2019 Peer-reviewed
Oxomollugin誘導体の抗炎症作用

中嶋祐輝, 坪井尚秀, 香取久美子, NUGROHO Alfarius Eko, 平澤祐介, 川崎洋子, 合田幸広, 金田利夫, 森田博史

日本生薬学会年会講演要旨集, 66th, 2019
Cycloartane triterpenoid (23R, 24E)-23-acetoxymangiferonic acid inhibited proliferation and migration in B16-F10 melanoma via MITF downregulation caused by inhibition of both β-catenin and c-Raf-MEK1-ERK signaling axis.

Kaneda T, Matsumoto M, Sotozono Y, Fukami S, Nugroho AE, Hirasawa Y, Hamid A HA, Morita H

Journal of natural medicines, 73(1) 47-58, Jan, 2019 Peer-reviewed

Misc.

192

ニチニチソウから単離された二量体アルカロイドisovincathicineの細胞増殖阻害作用

廣木美月, ABULIKEMU Aishanjiang, 戸塚千尋, 平澤祐介, 金田利夫, 森田博史

日本生薬学会年会講演要旨集, 68th, 2022
Chisocheton ceramicusより単離されたceramicine Bの酸化ストレス応答

出嶋堪哉, WONG Chin Piow, NUGROHO Alfarius Eko, 小泉瑤華, 金田利夫, 平澤祐介, 森田博史

日本生薬学会年会講演要旨集, 68th, 2022
OxomolluginのNF-κBシグナル阻害作用に関する検討

WAILI Maigunuer, 中嶋祐輝, 坪井尚秀, 香取久美子, NUGROHO Alfarius Eko, 平澤祐介, 高橋万紀, 川崎洋子, 合田幸広, 金田利夫 …

日本生薬学会年会講演要旨集, 67th, 2021
キョウチクトウ科Voacanga grandifoliaの成分研究

陳垠志, 小野百合香, NUGROHO Alfarius Eko, 平澤祐介, 金田利夫, ZAINI Noor Cholies, 森田博史

日本生薬学会年会講演要旨集, 66th, 2019
レンプクソウ科Sambucus sieboldianaに含まれる免疫賦活物質について

沈欣栄, 唐怡鳴, 平澤祐介, 金田利夫, 森田博史

植物化学シンポジウム, 56th (CD-ROM), 2019
骨巨細胞腫に対するcyclolinopeptideの抗腫瘍効果の検討

谷口裕太, 山本憲男, 林克洋, 武内章彦, 三輪真嗣, 五十嵐健太郎, 米澤宏隆, 亀井淳三, 金田利夫, 森田博史 …

日本整形外科学会雑誌, 93(8), 2019
キョウチクトウ科Leuconotis eugenifoliusより単離した新規アルカロイドの構造

唐怡鳴, NUGROHO Alfarius Eko, WONG Chin Piow, 平澤祐介, 金田利夫, HADI A. Hamid A., 森田博史

日本生薬学会年会講演要旨集, 66th, 2019
センダン科Chukrasia velutinaの成分探索

丹下雅貴, 日下部寿美, NUGROHO Alfarius Eko, 平澤祐介, 金田利夫, 森田博史, 松野倫代, 幾井康仁, 水上元

日本生薬学会年会講演要旨集, 65th, 2018
キョウチクトウ科Leuconotis eugenifoliusより単離した新規アルカロイドの構造と活性

唐怡鳴, 張ぶん佳, NUGROHO Alfarius Eko, WONG Chin Piow, 平澤祐介, 金田利夫, 森田博史

日本生薬学会年会講演要旨集, 65th, 2018
センダン科Chisocheton ceramicusの成分研究

NUGROHO Alfarius Eko, 吉川夏生, 岡部真理佳, 小室智之, WONG Chin Piow, 平澤祐介, 金田利夫, HADI A. Hamid A., 森田博史

日本生薬学会年会講演要旨集, 65th, 2018
ゴボウシより単離した新規リグナンの構造

平澤祐介, 清水雅祐美, 内山奈穂子, NUGROHO Alfarius Eko, 金田利夫, 袴塚高志, 森田博史

日本生薬学会年会講演要旨集, 65th, 2018
Calophyllum scriblitifoliumより単離したCalofolic acid Aの血管平滑筋弛緩作用について

深見聡, 金田利夫, IFADOTUNNIKMAH Farida, 佐々木忠裕, NUGROHO Alfarius Eko, HADI A. Hamid A., 森田博史

日本生薬学会年会講演要旨集, 65th, 2018
骨巨細胞腫に対するアマ由来環状ペプチドの抗腫瘍効果

谷口裕太, 山本憲男, 林克洋, 武内章彦, 樋口貴史, 阿部健作, 相羽久輝, 荒木麗博, 亀井淳三, 金田利夫 …

日本整形外科学会雑誌, 91(8), 2017
キョウチクトウ科Leuconotis griffithiiより単離した新規アルカロイドの構造と活性

唐怡鳴, 張ぶん佳, NUGROHO Alfarius Eko, WONG Chin Piow, 平澤祐介, 金田利夫, HADI A.Hamid A., 森田博史

日本生薬学会年会講演要旨集, 64th, 2017
ビャクブ科Croomia heterosepalaの成分研究

金子樹, NUGROHO Alfarius Eko, 金田利夫, 代田修, 森田博史

日本生薬学会年会講演要旨集, 64th, 2017
テリハボク科Calophyllum scriblitifoliumの成分研究

小笠原愛, NUGROHO Alfarius Eko, 野口亮, 佐々木忠裕, WONG Chin Piow, 平澤祐介, 金田利夫, HADI A.Hamid A., 森田博史

日本生薬学会年会講演要旨集, 64th, 2017
センダン科Chisocheton ceramicusの成分研究

吉川夏生, 岡部真理佳, NUGROHO Alfarius Eko, 小室智之, WONG Chin Piow, 平澤祐介, 金田利夫, HADI A.Hamid A., 森田博史

日本生薬学会年会講演要旨集, 64th, 2017
9-MethoxyellipticineのC/EBP β発現抑制機序に関する研究

野口真紀子, WONG Chin Piow, 橘川侑季, 関詩織, 金田利夫, 森田博史

日本生薬学会年会講演要旨集, 64th, 2017
Oxomolluginの抗炎症作用のメカニズムの解明

坪井尚秀, 香取久美子, NUGROHO Alfarius Eko, WONG Chin Piow, 平澤祐介, 川崎洋子, 合田幸広, 金田利夫, 森田博史

日本生薬学会年会講演要旨集, 64th, 2017
エゾユズリハ由来Daphnezomine Bの破骨細胞形成抑制作用

越川彩瑛, 佐々木燿, 吉川ゆうみ, NUGROHO Alfarius Eko, 金田利夫, 森田博史

日本生薬学会年会講演要旨集, 64th, 2017

Books and Other Publications

パートナー天然物化学改訂第2版〜第4版

金田利夫

南江堂

Teaching Experience

Sep, 2017 - Present

bioorganic chemistry (Hoshi University)
Apr, 2010 - Present

薬になる天然資源 (星薬科大学)

Professional Memberships

Research Projects

A study of searching for immunostimulating natural products

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

Kaneda Toshio
Research for natural products including alkaloids that inhibit TRP channels

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2013 - 2015

Kaneda Toshio, MORITA Hiroshi
The elucidation of the role of lipid in bone resorption of inflammatory bone diseases; in particular, the exploration of the role of LOX-1 as an oxidized LDL receptor

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, 2013 - 2015

HAKEDA Yoshiyuki, SATO Takuya, OKAYASU Mari, OGASAWARA Toru, SAWAMURA Tatsuya, ITO Junta, HAYASHIDA Chiyomi, KANEDA Toshio
DEPENDENCY OF OSTEOCLAST DIFFERENTIATION ON EXOGENOUS CHOLESTEROL AND ROLE OF CAVEOLIN-1 IN OSTEOCLASTOGENESIS

Grants-in-Aid for Scientific Research(基盤研究(C)), 基盤研究(C), Ministry of Education, Culture, Sports, Science and Technology, 2009 - 2011

Yoshiyuki HAKEDA, 増原正明, Takuya SATO, Toshio KANEDA, Masaaki MASUHARA
白血病発症におけるE3ユビキチン・リガーゼの機能解析とその臨床応用

科学研究費助成事業基盤研究(C), 基盤研究(C), 日本学術振興会, 2005 - 2006

武藤章弘, 吉田正, 金田利夫, 木崎昌弘
Study on the immunological mechanism of anti-TSH receptor antibody production by using transgenic mice

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, 2003 - 2005

YOSHIDA Tadashi, MUTO Akihiro, KANEDA Toshio
Elucidation of role of beta ig-3 derived from osteoclasts in bone resorption and formation

Grants-in-Aid for Scientific Research(基盤研究(C)), 基盤研究(C), Ministry of Education, Culture, Sports, Science and Technology, 2003 - 2004

Yoshiyuki HAKEDA, Toshio KANEDA, Takuya SATO, Masaaki MASUHARA

Profile Information

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Papers

Misc.

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