SADO Takashi

J-GLOBAL         Last updated: May 18, 2016 at 02:46
 
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Name
SADO Takashi
Affiliation
Kindai University
Section
Faculty of Agriculture Department of Advanced Bioscience
Job title
Associate Professor
Degree
Ph. D.

Research Areas

 
 

Academic & Professional Experience

 
May 2009
   
 
Associate professor, Medical Institute of Bioregulation, Kyushu Univ.
 
1999
   
 
- National Institute of Genetics, Assist. Professor
 
2000
   
 
- Graduate University for Advanced studies, Assist.
 
 
   
 
Professor
 

Education

 
 
   
 
Hokkaido University
 

Published Papers

 
A new Xist allele driven by a constitutively active promoter is dominated by Xist locus environment and exhibits the parent-of-origin effects.
†Amakawa, Y., †Sakata, Y., Hoki, Y., Arata, S., Shioda, S., Fukagawa, T., Sasaki, H., and *Sado, T.
Development   142 4299-4308   Dec 2015   [Refereed]
An Xist Activating Antisense RNA Required for X-chromosome Inactivation.
Sarkar, M., Gayen, S., Kumar, S., Maclary, E., Buttigieg, E., Hinten, M., Kumari, A., Harris, C., Sado, T., and *Kalantry, S.
Nature comm.   6 8564-ST008028   Oct 2015   [Refereed]
Shinagawa T, Takagi T, Tsukamoto D, Tomaru C, Huynh LM, Sivaraman P, Kumarevel T, Inoue K, Nakato R, Katou Y, Sado T, Takahashi S, Ogura A, Shirahige K, Ishii S
Cell stem cell   14 217-227   Feb 2014   [Refereed]
Kagawa N, Hori T, Hoki Y, Hosoya O, Tsutsui K, Saga Y, Sado T, Fukagawa T
Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology      Jan 2014   [Refereed]
X chromosome reactivation dynamics reveal stages of reprogramming to pluripotency
Pasque, V., Tchieu, J., Karnik, R., Uyeda, M., Sadhu Dimashkie, A., Case, D., Papp, B., Bonora, G., Patel, S., Ho, R., Schmidt, R., McKee, R., Sado, T., Tada, T., Meissner, A., and *Plath, K.
Cell   159 1681-1697   Dec 2014   [Refereed]
Sado T, Sakaguchi T
Reproduction (Cambridge, England)   146 R131-9   Oct 2013   [Refereed]
Nozawa RS, Nagao K, Igami KT, Shibata S, Shirai N, Nozaki N, Sado T, Kimura H, Obuse C
Nature structural & molecular biology   20 566-573   May 2013   [Refereed]
Yamamoto Y, Watanabe T, Hoki Y, Shirane K, Li Y, Ichiiyanagi K, Kuramochi-Miyagawa S, Toyoda A, Fujiyama A, Oginuma M, Suzuki H, Sado T, Nakano T, Sasaki H
Genome research   23 292-299   Feb 2013   [Refereed]
Sado T, Brockdorff N
Philosophical transactions of the Royal Society of London. Series B, Biological sciences   368 20110325   Jan 2013   [Refereed]
Hoki Y, Ikeda R, Mise N, Sakata Y, Ohhata T, Sasaki H, Abe K, Sado T
Development (Cambridge, England)   138 2649-2659   Jul 2011   [Refereed]
Watanabe T, Tomizawa S, Mitsuya K, Totoki Y, Yamamoto Y, Kuramochi-Miyagawa S, Iida N, Hoki Y, Murphy PJ, Toyoda A, Gotoh K, Hiura H, Arima T, Fujiyama A, Sado T, Shibata T, Nakano T, Lin H, Ichiyanagi K, Soloway PD, Sasaki H
Science (New York, N.Y.)   332 848-852   May 2011   [Refereed]
Watanabe T, Chuma S, Yamamoto Y, Kuramochi-Miyagawa S, Totoki Y, Toyoda A, Hoki Y, Fujiyama A, Shibata T, Sado T, Noce T, Nakano T, Nakatsuji N, Lin H, Sasaki H
Developmental cell   20 364-375   Mar 2011   [Refereed]
Inoue K, Kohda T, Sugimoto M, Sado T, Ogonuki N, Matoba S, Shiura H, Ikeda R, Mochida K, Fujii T, Sawai K, Otte AP, Tian XC, Yang X, Ishino F, Abe K, Ogura A
Science (New York, N.Y.)   330 496-499   Oct 2010   [Refereed]
Sex-reversed somatic cell cloning in the mouse.
Inoue K, Ogonuki N, Mekada K, Yoshiki A, Sado T, Ogura A
The Journal of reproduction and development   55 566-569   Oct 2009   [Refereed]
Chiba H, Hirasawa R, Kaneda M, Amakawa Y, Li E, Sado T, Sasaki H
Genesis (New York, N.Y. : 2000)   46 spc one   Dec 2008   [Refereed]
Nesterova TB, Popova BC, Cobb BS, Norton S, Senner CE, Tang YA, Spruce T, Rodriguez TA, Sado T, Merkenschlager M, Brockdorff N
Epigenetics & chromatin   1 2   Oct 2008   [Refereed]
Ohhata T, Hoki Y, Sasaki H, Sado T
Development (Cambridge, England)   135 227-235   Jan 2008   [Refereed]
Sado T, Hoki Y, Sasaki H
Development (Cambridge, England)   133 4925-4931   Dec 2006   [Refereed]
Ohhata T, Hoki Y, Sasaki H, Sado T
Cytogenetic and genome research   113 345-349   2006   [Refereed]
Sado T, Hoki Y, Sasaki H
Developmental cell   9 159-165   Jul 2005   [Refereed]
Sado T, Ferguson-Smith AC
Human molecular genetics   14 Spec No 1 R59-64   Apr 2005   [Refereed]
Large-scale identification and mapping of nuclear matrix-attachment regions in the distal imprinted domain of mouse chromosome 7.
Purbowasito W, Suda C, Yokomine T, Zubair M, Sado T, Tsutsui K, Sasaki H
DNA research : an international journal for rapid publication of reports on genes and genomes   11 391-407   Dec 2004   [Refereed]
Ohhata T, Tachibana M, Tada M, Tada T, Sasaki H, Shinkai Y, Sado T
Genesis (New York, N.Y. : 2000)   40 151-156   Nov 2004   [Refereed]
Kaneda M, Okano M, Hata K, Sado T, Tsujimoto N, Li E, Sasaki H
Nature   429 900-903   Jun 2004   [Refereed]
Sado T, Okano M, Li E, Sasaki H
Development (Cambridge, England)   131 975-982   Mar 2004   [Refereed]
Kaneda M, Sado T, Hata K, Okano M, Tsujimoto N, Li E, Sasaki H
Cold Spring Harbor symposia on quantitative biology   69 125-129   2004   [Refereed]
Shirohzu H, Kubota T, Kumazawa A, Sado T, Chijiwa T, Inagaki K, Suetake I, Tajima S, Wakui K, Miki Y, Hayashi M, Fukushima Y, Sasaki H
American journal of medical genetics   112 31-37   Sep 2002   [Refereed]
Sado T, Li E, Sasaki H
Cytogenetic and genome research   99 115-118   2002   [Refereed]
Takebayashi S, Nakao M, Fujita N, Sado T, Tanaka M, Taguchi H, Okumura K
Biochemical and biophysical research communications   288 921-926   Nov 2001   [Refereed]
Regulation of imprinted X-chromosome inactivation in mice by Tsix.
Sado T, Wang Z, Sasaki H, Li E
Development (Cambridge, England)   128 1275-1286   Apr 2001   [Refereed]
Relationship between DNA methylation, histone H4 acetylation and gene expression in the mouse imprinted Igf2-H19 domain.
Grandjean V, O'Neill L, Sado T, Turner B, Ferguson-Smith A
FEBS letters   488 165-169   Jan 2001   [Refereed]
Sado T, Fenner MH, Tan SS, Tam P, Shioda T, Li E
Developmental biology   225 294-303   Sep 2000   [Refereed]
Effect of CpG methylation on expression of the mouse imprinted gene Mest.
Nishita Y, Sado T, Yoshida I, Takagi N
Gene   226 199-209   Jan 1999   [Refereed]
Schuster-Gossler K, Bilinski P, Sado T, Ferguson-Smith A, Gossler A
Developmental dynamics : an official publication of the American Association of Anatomists   212 214-228   Jun 1998   [Refereed]
Epigenotype switching of imprintable loci in embryonic germ cells.
Tada T, Tada M, Hilton K, Barton SC, Sado T, Takagi N, Surani MA
Development genes and evolution   207 551-561   Feb 1998   [Refereed]
Nishita Y, Yoshida I, Sado T, Takagi N
Genomics   36 539-542   Sep 1996   [Refereed]
Sado T, Tada T, Takagi N
Developmental dynamics : an official publication of the American Association of Anatomists   205 421-434   Apr 1996   [Refereed]

Research Grants & Projects

 
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(新学術領域研究(研究領域提案型))
Project Year: 2009 - 2013    Investigator(s): Takashi SADO
In this mission, we attempted to figure out the regulatory mechanisms of Xist RNA machinery, which has been known for many years to play a pivotal role in X chromosome inactivation in female mammals. Especially, we focused on the potential role of...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(B))
Project Year: 2008 - 2010    Investigator(s): Takashi SADO
X chromosome inactivation (X-inactivation) in female mammals is triggered by differential upregulation of the Xist gene on one of the two X chromosomes and subsequent coating of the X in cis with its noncoding transcripts. Although targeted mutati...
Molecular Mechanisms of X-inactivation
Project Year: 1999