Daigo Wakana

Profile Information

Affiliation: Hoshi University

Degree: 薬学博士(星薬科大学大学院)

J-GLOBAL ID: 200901096464552214
researchmap Member ID: 5000092087

Research Areas

Research History

2014

Hoshi University, Hoshi University

Papers

Ergot alkaloids in sclerotia collected in Japan: synthetic profiles and induction of apoptosis by Clavine-type compounds

Yuji Doi, Daigo Wakana, Satoshi Kitaoka, Fumiaki Sato, Eiji Tanaka, Hisashi Takeda, Tomoo Hosoe

Journal of Natural Medicines, Jan 12, 2023
Secalonic Acid and Benzoic Acid Analogues Exhibiting Cyto toxicity against Cancer Cells Isolated from Claviceps yanagawaensis

Yuji Doi, Daigo Wakana, Satoshi Kitaoka, Hisashi Takeda, orcid, Eiji Tanaka, Tomoo Hosoe

Advances in Microbiology, 12(12) 649-670, Dec, 2022 Peer-reviewed
Production of Ergot Alkaloids by the Japanese Isolate Claviceps purpurea var. agropyri on Rice Medium

Yuji Doi, Daigo Wakana, Hisashi Takeda, Eiji Tanaka, Tomoo Hosoe

Advances in Microbiology, 12(4) 254-269, Apr, 2022 Peer-reviewed
Effect of Crude Drug Extracts on Trypacidin Production in &lt;i&gt;Aspergillus fumigatus&lt;/i&gt;

Daigo Wakana, Nobuhiro Inoue, Hisashi Takeda, Tomoo Hosoe

Advances in Microbiology, 12(09) 541-554, 2022
Elucidation of degradation behavior of tricyclic antidepressant amoxapine in artificial gastric juice

Koichi Saito, Nami Hagiwara, Miho Sakamoto, Daigo Wakana, Rie Ito, Tomoo Hosoe

Chemical and Pharmaceutical Bulletin, 68(9) 848-854, Sep 1, 2020
Characterization of Burkholderia sp. strain CJ1, a newly isolated berberine-degrading bacterium from rhizosphere of Coptis japonica

Hinaka Yoshida, Hisashi Takeda, Daigo Wakana, Tomoo Hosoe

Bioscience, Biotechnology, and Biochemistry, 84(6) 1299-1302, Jun 2, 2020
Identification of a multi-component berberine 11-hydroxylase from Burkholderia sp. strain CJ1.

Hinaka Yoshida, Hisashi Takeda, Daigo Wakana, Fumihiko Sato, Tomoo Hosoe

Bioscience, biotechnology, and biochemistry, 84(6) 1274-1284, Jun, 2020
Identifying the compounds that can distinguish between Saposhnikovia root and its substitute, Peucedanum ledebourielloides root, using LC-HR/MS metabolomics

Taichi Yoshitomi, Daigo Wakana, Nahoko Uchiyama, Takashi Tsujimoto, Noriaki Kawano, Tsuguo Yokokura, Yutaka Yamamoto, Hiroyuki Fuchino, Takashi Hakamatsuka, Katsuko Komatsu …

Journal of Natural Medicines, 74(3) 550-560, Jun 1, 2020 Peer-reviewed
Shimalactone Biosynthesis Involves Spontaneous Double Bicyclo‐Ring Formation with 8π‐6π Electrocyclization

Isao Fujii, Makoto Hashimoto, Kaori Konishi, Akiko Unezawa, Haruka Sakuraba, Kenta Suzuki, Harue Tsushima, Miho Iwasaki, Satsuki Yoshida, Akane Kudo …

Angewandte Chemie, 132(22) 8542-8548, May 25, 2020
Shimalactone Biosynthesis Involves Spontaneous Double Bicyclo-Ring Formation with 8π-6π Electrocyclization

Isao Fujii, Makoto Hashimoto, Kaori Konishi, Akiko Unezawa, Haruka Sakuraba, Kenta Suzuki, Harue Tsushima, Miho Iwasaki, Satsuki Yoshida, Akane Kudo …

Angewandte Chemie - International Edition, 59(22) 8464-8470, May 25, 2020
¹H NMR-based metabolomic analysis coupled with reversed-phase solid-phase extraction for sample preparation of Saposhnikovia roots and related crude drugs

Taichi Yoshitomi, Daigo Wakana, Nahoko Uchiyama, Takashi Tsujimoto, Noriaki Kawano, Tsuguo Yokokura, Yutaka Yamamoto, Hiroyuki Fuchino, Takashi Hakamatsuka, Katsuko Komatsu …

Journal of Natural Medicines, 74(1) 65-75, Jan 1, 2020 Peer-reviewed
Antifungal Activity of Compounds Isolated from Bamboo Vermicompost against Rhizoctonia solani AG1-IB

Xiaodong You, Daigo Wakana, Kazuki Ishikawa, Tomoo Hosoe, Motoaki Tojo

Advances in Microbiology, 9(12) 957-970, Dec, 2019 Peer-reviewed
Antimicrobial agent isolated from Coptidis rhizome extract incubated with Rhodococcus sp. strain BD7100

Kazuki Ishikawa, Kazunori Takahashi, Syun Hosoi, Hisashi Takeda, Hinaka Yoshida, Daigo Wakana, Masayoshi Tsubuki, Fumihiko Sato, Motoaki Tojo, Tomoo Hosoe

Journal of Antibiotics, 72(2) 71-78, Feb 1, 2019 Peer-reviewed
Effect of Shakuyaku-kanzo-to and other crude drug components of Kampo medicines on sterigmatocystin production by Emericella nidulans

Nobuhiro Inoue, Daigo Wakana, Hisashi Takeda, Takashi Yaguchi, Tomoo Hosoe

JSM Mycotoxins, 68(1) 19-25, 2018
Production of an emericellin and its analogues as fungal biological responses for Shimbu-to extract

Nobuhiro Inoue, Daigo Wakana, Hisashi Takeda, Takashi Yaguchi, Tomoo Hosoe

Journal of Natural Medicines, 72(1) 357-363, Jan 1, 2018
Four cyclodipeptides, asnovolenins A-B and asnovozines A-B, from aspergillus novofumigatus

Kazuki Ishikawa, Daigo Wakana, Takeshi Itabashi, Hisashi Takeda, Takashi Yaguchi, Ken ichi Kawai, Tomoo Hosoe

Heterocycles, 96(6) 1053-1065, 2018 Peer-reviewed
Common origin of methylenedioxy ring degradation and demethylation in bacteria

Hisashi Takeda, Kazuki Ishikawa, Hinaka Yoshida, Daisuke Kasai, Daigo Wakana, Masao Fukuda, Fumihiko Sato, Tomoo Hosoe

Scientific Reports, 7(1) 7422, Dec 1, 2017 Peer-reviewed
Construction of Prediction Models for the Transient Receptor Potential Vanilloid Subtype 1 (TRPV1)-Stimulating Activity of Ginger and Processed Ginger Based on LC-HRMS Data and PLS Regression Analyses

Taichi Yoshitomi, Naohiro Oshima, Yuto Goto, Shunsuke Nakamori, Daigo Wakana, Naoko Anjiki, Koji Sugimura, Noriaki Kawano, Hiroyuki Fuchino, Osamu Iida …

Journal of Agricultural and Food Chemistry, 65(17) 3581-3588, May 3, 2017 Peer-reviewed
New two pebrolide derivatives, 14-deacetoxy-1-deoxypebrolide and 7'-hydroxyasperphenamate isolated from penicillium Sp. IFM62525

Syuhei Arai, Daigo Wakana, Takeshi Itabashi, Hisashi Takeda, Takashi Yaguchi, Galba Maria De Campos Takaki, Tomoo Hosoe

Heterocycles, 94(2) 326-333, 2017
Asnovolins A-G, Spiromeroterpenoids Isolated from the Fungus Aspergillus novofumigatus, and Suppression of Fibronectin Expression by Asnovolin e

Kazuki Ishikawa, Fumiaki Sato, Takeshi Itabashi, Hiroshi Wachi, Hisashi Takeda, Daigo Wakana, Takashi Yaguchi, Ken Ichi Kawai, Tomoo Hosoe

Journal of Natural Products, 79(9) 2167-2174, Sep 23, 2016 Peer-reviewed

Misc.

4年制薬学教育における「学外体験学習(長期インターンシップ)」による社会人基礎力養成の試み

細江智夫, 山本弘, 酒井寛泰, 五十嵐信智, 今理紗子, 加藤良規, 岩崎雄介, 武田尚, 若菜大悟, 吉澤小百合[渡邉] …

日本薬学会年会要旨集, 141年会 28P01-283, Mar, 2021
4年制薬学教育における「学外体験学習(長期インターンシップ)」による社会人基礎力養成の試み

細江智夫, 山本弘, 酒井寛泰, 五十嵐信智, 今理紗子, 加藤良規, 岩崎雄介, 武田尚, 若菜大悟, 吉澤(渡邉) 小百合 …

日本薬学会年会要旨集, 141年会 28P01-283, Mar, 2021
Study of large scale culture of reclassifying Claviceps spp. collected in Japan

Doi Y., Wakana D., Takeda H., Tanaka E., Hosoe T.

Abstracts of Papers Presented at the Meeting of the Mycological Society of Japan, 64 29, 2020
皮膚に対するチンピ抽出物の新規機能の探索

裴宸晨, 金子未歩, 川崎藍, 田中李歩, 高山直也, 若菜大吾, 細江智夫, 今理紗子, 五十嵐信智, 酒井寛泰 …

日本薬学会年会要旨集, 139年会(3) 105-105, Mar, 2019
¹H-NMRメタボロームによるサンシシの品質多様性評価

後藤佑斗, 辻本恭, 吉冨太一, 若菜大悟, 内山奈穂子, 白畑辰弥, 袴塚高志, 丸山卓郎, 小林義典

日本薬学会年会要旨集(CD-ROM), 139th, 2019
Berberine資化性菌Burkholderia sp.CJ1株におけるberberine11位水酸化酵素遺伝子群の特定

吉田陽菜花, 石川和樹, 武田尚, 若菜大悟, 笠井大輔, 福田雅夫, 佐藤文彦, 細江智夫

日本薬学会年会要旨集(CD-ROM), 139th, 2019
Sphingobium sp.BD3100株のベルベリン脱メチレン化酵素遺伝子の転写誘導

武田尚, 宮内啓介, 若菜大悟, 細江智夫

環境バイオテクノロジー学会大会プログラム講演要旨集, 2018 55, Jun 25, 2018
逆相系固相抽出による試料調製を利用したボウフウ類生薬の¹H‐NMRメタボローム解析と特徴成分の同定

吉冨太一, 若菜大悟, 内山奈穂子, 河野徳昭, 横倉胤夫, 山本豊, 渕野裕之, 小松かつ子, 川原信夫, 丸山卓郎

日本薬学会年会要旨集(CD-ROM), 138th ROMBUNNO.27PA‐am209, 2018
¹H‐NMRメタボローム解析を用いたショウキョウ,カンキョウの品質の多様性評価について

吉冨太一, 内山奈穂子, 白畑辰弥, 若菜大悟, 安食菜穂子, 杉村康司, 渕野裕之, 袴塚高志, 飯田修, 川原信夫 …

日本薬学会年会要旨集(CD-ROM), 137th ROMBUNNO.26PA‐am055, 2017
Sphingobium sp.BD3100株のベルベリン脱メチレン化酵素の誘導性

武田尚, 若菜大悟, 宮内啓介, 細江智夫

日本微生物生態学会大会(Web), 2017 ROMBUNNO.P‐147 (WEB ONLY), 2017
ショウキョウ及びカンキョウのTRPV1賦活活性予測モデル式の構築と構造活性相関について

吉冨太一, 後藤佑斗, 袴塚高志, 丸山卓郎, 大嶋直浩, 中森俊輔, 小林義典, 安食菜穂子, 杉村康司, 渕野裕之 …

日本食品化学学会総会・学術大会講演要旨集, 22nd 84, Jun 2, 2016
LC-HRMSデータによるショウキョウ及びカンキョウのTRPV1賦活活性予測モデル式について

吉冨太一, 後藤佑斗, 袴塚高志, 丸山卓郎, 大嶋直浩, 中森俊輔, 小林義典, 安食菜穂子, 杉村康司, 淵野裕之 …

日本薬学会年会要旨集, 136年会(2) 205-205, Mar, 2016
メタボロミクスを用いたショウガ品種の分類と含有化学成分の観点から見た特徴の調査

若菜大悟

日本食品化学研究振興財団研究成果報告書, (21) 109-112, Nov 30, 2015
Aspergillus novofumigatusの第二次代謝産物の立体化学に関する考察

石川和樹, 若菜大悟, 武田尚, 矢口貴志, 細江智夫

日本菌学会大会講演要旨集, 59th 42, Apr 27, 2015
漢方薬がAspergillus nidulansの第二次代謝産物に与える影響

井上信宏, 若菜大悟, 武田尚, 矢口貴志, 細江智夫

日本菌学会大会講演要旨集, 59th 103, Apr 27, 2015
berberine資化性菌のberberine分解酵素の誘導性と基質特異性

山崎美葵, 石川和樹, 武田尚, 若菜大悟, 佐藤文彦, 細江智夫

日本薬学会年会要旨集(CD-ROM), 135th ROMBUNNO.27PB-PM222, 2015
Sida属植物の組織形態学的研究(6)

榊真由, 山路誠一, 伏谷眞二, 若菜大悟, 丸山卓郎, 鎌倉浩之, 合田幸広, 杉村康司, 飯田修, 李昭瑩

日本薬学会年会要旨集(CD-ROM), 135th ROMBUNNO.27PB-AM150S, 2015
Berberine資化性菌のberberrubine分解能に関する研究

吉田陽菜花, 石川和樹, 武田尚, 若菜大悟, 佐藤文彦, 細江智夫

日本薬学会年会要旨集(CD-ROM), 135th ROMBUNNO.27PB-PM215, 2015
Berberine資化性菌によるオウレン由来アルカロイドの分解挙動について

石川和樹, 武田尚, 若菜大悟, 佐藤文彦, 細江智夫

日本薬学会年会要旨集(CD-ROM), 135th ROMBUNNO.27PB-PM219, 2015
漢方薬がAspergillus nidulansの二次代謝産物に与える影響

井上信宏, 若菜大悟, 武田尚, 矢口貴志, 細江智夫

日本薬学会年会要旨集(CD-ROM), 135th ROMBUNNO.27PB-PM247S, 2015

Research Projects

Production of diversity extract library for creation of new biological resources

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2019

Wakana Daigo
An attempt to produce functional molecular as fungal biological responses for Kampo medicine and the other crude drug components

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Hosoe Tomoo, INOUE Nobuhiro, KISHIDA Satoshi
Investigation of rice component inducing the production of malbrancheoside A from Malbranchea filamentosa

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2014 - Mar, 2017

WAKANA Daigo

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