Ken Tanaka

Profile Information

Affiliation: Professor, School of Materials and Chemical Technology, Tokyo Institute of Technology

Degree: Doctor (Agriculture)(The University of Tokyo)

Researcher number: 40359683
J-GLOBAL ID: 200901007799166448
researchmap Member ID: 5000041228

Research Interests

Research Areas

Research History

Education

Committee Memberships

Awards

2009

Thieme Journal Award 2010
2009

Thieme Journal Award 2010
2006

Solvias Ligand Contest 2006: First Prize
2006

Solvias Ligand Contest 2006: First Prize
2003

Banyu Pharmaceutical Company Award in Synthetic Organic Chemistry, Japan
2003

有機合成化学協会研究企画賞
2001

Synthetic Organic Chemistry Award, Japan
2001

有機合成化学協会賞（技術的）

Papers

323

Rh-Catalyzed Enantioselective Hydroalkenylative Cyclization of 1,6-Enynes Constructing All-Carbon Quaternary Stereocenters

Shunsuke Emi, Shintaro Hamada, Yuko Kishida, Yu Sato, Futo Morita, Yuki Nagashima, Hidehiro Uekusa, Ken Tanaka

ACS Catalysis, 4951-4957, Mar 18, 2024
Visible-Light-Induced trans-Hydroboration of Diaryl Alkynes Utilizing Excited State of Borate Complexes

Takahiro Komaki, Yu Sato, Masanobu Uchiyama, Ken Tanaka, Yuki Nagashima

Organic Letters, Mar 11, 2024
電気陽性な典型元素の励起状態を利用する光反応の開発

Yuki Nagashima, Masanobu Uchiyama, Ken Tanaka

Journal of Synthetic Organic Chemistry, Japan, 81(10) 930-940, Oct 1, 2023
Computational Mechanistic Study on Intramolecular Triple Cyclization of 1-Biphenylethynyl-2-phenylethynylbenzenes Giving Spiro Fluorene-Phenylenevinylenes by Dual Catalysis

Yuki Nagashima, Seiya Ouchi, Tomonori Inoue, Ken Tanaka

Bulletin of the Chemical Society of Japan, 96(7) 717-723, Jul 15, 2023
Enantioselective Synthesis of Axially Chiral Figure-Eight Spirocycloparaphenylenes via Rh-Catalyzed Intermolecular [2 + 2 + 2] Cycloaddition

Li-Hsiang Wang, Juntaro Nogami, Yuki Nagashima, Ken Tanaka

Organic Letters, May 23, 2023
Catalytic stereoselective synthesis of doubly, triply and quadruply twisted aromatic belts

Juntaro Nogami, Daisuke Hashizume, Yuki Nagashima, Kazunori Miyamoto, Masanobu Uchiyama, Ken Tanaka

Nature Synthesis, May 22, 2023
Shape‐ and Size‐Tunable Synthesis of Covalent Organic Cages through Rh‐Catalyzed Regioselective [2+2+2] Cycloaddition

Yu Sato, Masato Abekura, Tomohiro Oriki, Yuki Nagashima, Hidehiro Uekusa, Ken Tanaka

Angewandte Chemie International Edition, Apr 11, 2023
Design, synthesis and visible-light-induced non-radical reactions of dual-functional Rh catalysts

Seiya Ouchi, Tomonori Inoue, Juntaro Nogami, Yuki Nagashima, Ken Tanaka

Nature Synthesis, 2, Mar 30, 2023
An Electron-Deficient CpE Iridium(III) Catalyst: Synthesis, Characterization, and Application to Ether-Directed C-H Amidation.

Eiki Tomita, Masahiro Kojima, Yuki Nagashima, Ken Tanaka, Haruki Sugiyama, Yasutomo Segawa, Atsushi Furukawa, Katsumi Maenaka, Satoshi Maeda, Tatsuhiko Yoshino …

Angewandte Chemie (International ed. in English), 62(21) e202301259, Mar 14, 2023
Rhodium‐Catalyzed Chemo‐, Regio‐, Diastereo‐, and Enantioselective Intermolecular [2+2+2] Cycloaddition of Three Unsymmetric 2π Components

Ryota Shimotsukue, Kohei Fujii, Yu Sato, Yuki Nagashima, Ken Tanaka

Angewandte Chemie International Edition, Mar 6, 2023
Dearomative triple elementalization of quinolines driven by visible light

Shiho Ishigaki, Yuki Nagashima, Daiki Yukimori, Jin Tanaka, Takashi Matsumoto, Kazunori Miyamoto, Masanobu Uchiyama, Ken Tanaka

Nature Communications, 14(1), Feb 6, 2023
Room Temperature Fluoranthene Synthesis through Cationic Rh(I)/H₈-BINAP-Catalyzed [2 + 2 + 2] Cycloaddition: Unexpected Acceleration due to Noncovalent Interactions

Ryota Abe, Yuki Nagashima, Jin Tanaka, Ken Tanaka

ACS Catalysis, 13(3) 1604-1613, Jan 12, 2023
Stereoselective synthesis of [2.2]triphenylenophanes via intramolecular double [2 + 2 + 2] cycloadditions

Yuya Kawai, Juntaro Nogami, Yuki Nagashima, Ken Tanaka

Chemical Science, 2023
Catalyst-Controlled Inter- and Intramolecular Cascade [4 + 2] Annulations via Benzopyrylium Intermediates

Takumi Koshikawa, Juntaro Nogami, Yuki Nagashima, Ken Tanaka

ACS Catalysis, 12(22) 14330-14336, Nov 18, 2022
Native Amide‐Directed C(sp3)–H Amidation Enabled by Electron‐Deficient Rh(III) Catalyst and Electron‐Deficient 2‐Pyridone Ligand

Takumi Wakikawa, Daichi Sekine, Yuta Murata, Youka Bunno, Masahiro Kojima, Yuki Nagashima, Ken Tanaka, Tatsuhiko Yoshino, Shigeki Matsunaga

Angewandte Chemie International Edition, Oct 28, 2022 Peer-reviewed
Photocatalytic Generations of Secondary and Tertiary Silyl Radicals from Silylboranes Using an Alkoxide Cocatalyst

Ryo Arai, Yuki Nagashima, Takumi Koshikawa, Ken Tanaka

The Journal of Organic Chemistry, Oct 10, 2022
Regiodivergent Synthesis and π‐Stacking‐Induced Chiral Self‐Recognition of Hexabenzocoronene‐Based [6]Helicenes

Futo Morita, Juntaro Nogami, Antônio Junio Araujo Dias, Suzuka Kinoshita, Yuki Nagashima, Ken Tanaka

European Journal of Organic Chemistry, 2022(27), Jul 21, 2022
Stereoselective cyclohexadienylamine synthesis through rhodium-catalysed [2+2+2] cyclotrimerization

Kohei Fujii, Yuki Nagashima, Takumi Shimokawa, Junichiro Kanazawa, Haruki Sugiyama, Koji Masutomi, Hidehiro Uekusa, Masanobu Uchiyama, Ken Tanaka

Nature Synthesis, Mar 28, 2022
Enantioselective Synthesis of Axially Chiral Styrene‐Carboxylic Esters by Rhodium‐Catalyzed Chelation‐Controlled [2+2+2] Cycloaddition

Daisuke Yokose, Yuki Nagashima, Suzuka Kinoshita, Juntaro Nogami, Ken Tanaka

Angewandte Chemie International Edition, Mar 16, 2022
Rhodium‐Catalyzed Intermolecular Cycloaromatization Route to Cycloparaphenylenes that Exhibit Aggregation‐Induced Emission

Li-Hsiang Wang, Yuki Nagashima, Masato Abekura, Hidehiro Uekusa, Gen-ichi Konishi, Ken Tanaka

Chemistry – A European Journal, Feb 23, 2022

Misc.

185

Inside Cover: Rhodium(III)-Catalyzed Tandem [2+2+2] Annulation–Lactamization of Anilides with Two Alkynoates via Cleavage of Two Adjacent C−H or C−H/C−O bonds (Chem. Asian J. 16/2016)

Miho Fukui, Yu Shibata, Yuki Hoshino, Haruki Sugiyama, Kota Teraoka, Hidehiro Uekusa, Keiichi Noguchi, Ken Tanaka

Chemistry - An Asian Journal, 11(16) 2219, Aug 19, 2016
Transition-Metal-Catalyzed Cyclization of Alkynals via Oxametallacycle Intermediates

Ken Tanaka, Yuki Tajima

EUROPEAN JOURNAL OF ORGANIC CHEMISTRY, (20) 3715-3725, Jul, 2012
Cationic rhodium(I) complex-catalyzed sigma- and pi-bond activation cascade: Isomerization of allyl propargyl ethers to allenic aldehydes and dienals

Ken Tanaka, Eri Okazaki, Yu Shibata

PURE AND APPLIED CHEMISTRY, 82(7) 1453-1460, Jul, 2010
Cationic rhodium(I) complex-catalyzed sigma- and pi-bond activation cascade: Isomerization of allyl propargyl ethers to allenic aldehydes and dienals

Ken Tanaka, Eri Okazaki, Yu Shibata

PURE AND APPLIED CHEMISTRY, 82(7) 1453-1460, Jul, 2010
Rhodium-Catalyzed Complete Regioselective Intermolecular Cross-Cyclotrimerization of Aryl Ethynyl Ethers and Nitriles or Isocyanates at Room Temperature

Yoshiyuki Komine, Ken Tanaka

ORGANIC LETTERS, 12(6) 1312-1315, Mar, 2010
Asymmetric Synthesis and Photophysical Properties of Benzopyrano- or Naphthopyrano-Fused Helical Phosphafluorenes

Naahiro Fukawa, Takuya Osaka, Keiichi Noguchi, Ken Tanaka

ORGANIC LETTERS, 12(6) 1324-1327, Mar, 2010
Rhodium-Catalyzed Complete Regioselective Intermolecular Cross-Cyclotrimerization of Aryl Ethynyl Ethers and Nitriles or Isocyanates at Room Temperature

Yoshiyuki Komine, Ken Tanaka

ORGANIC LETTERS, 12(6) 1312-1315, Mar, 2010
Asymmetric Synthesis and Photophysical Properties of Benzopyrano- or Naphthopyrano-Fused Helical Phosphafluorenes

Naahiro Fukawa, Takuya Osaka, Keiichi Noguchi, Ken Tanaka

ORGANIC LETTERS, 12(6) 1324-1327, Mar, 2010
Rhodium-catalyzed convenient synthesis of functionalized tetrahydronaphthalenes

Ken Tanaka, Yayoi Sawada, Yusuke Aida, Maliny Thammathevo, Rie Tanaka, Hiromi Sagae, Yousuke Otake

TETRAHEDRON, 66(8) 1563-1569, Feb, 2010
Rhodium-Catalyzed Asymmetric Reductive Cyclization of Heteroatom-Linked 5-Alkynals with Heteroatom-Substituted Acetaldehydes

Rie Tanaka, Keiichi Noguchi, Ken Tanaka

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(4) 1238-+, Feb, 2010
Rhodium-catalyzed convenient synthesis of functionalized tetrahydronaphthalenes

Ken Tanaka, Yayoi Sawada, Yusuke Aida, Maliny Thammathevo, Rie Tanaka, Hiromi Sagae, Yousuke Otake

TETRAHEDRON, 66(8) 1563-1569, Feb, 2010
Rhodium-Catalyzed Asymmetric Reductive Cyclization of Heteroatom-Linked 5-Alkynals with Heteroatom-Substituted Acetaldehydes

Rie Tanaka, Keiichi Noguchi, Ken Tanaka

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 132(4) 1238-+, Feb, 2010
A New Route to Tricyclic 2-Pyridone Frameworks via Formation of Bicyclic N-Alkenyl Alkynylamides Followed by Gold-catalyzed Cycloisomerization

Hidetomo Imase, Ken Tanaka

CHEMISTRY LETTERS, 38(12) 1152-1153, Dec, 2009
A New Route to Tricyclic 2-Pyridone Frameworks via Formation of Bicyclic N-Alkenyl Alkynylamides Followed by Gold-catalyzed Cycloisomerization

Hidetomo Imase, Ken Tanaka

CHEMISTRY LETTERS, 38(12) 1152-1153, Dec, 2009
Synthesis of substituted 6-imino-2-piperidinones by Rh-catalyzed [4+2] annulation of 4-alkynals with carbodiimides

Ken Tanaka, Marina Mimura, Daiki Hojo

TETRAHEDRON, 65(44) 9008-9014, Oct, 2009
Synthesis of substituted 6-imino-2-piperidinones by Rh-catalyzed [4+2] annulation of 4-alkynals with carbodiimides

Ken Tanaka, Marina Mimura, Daiki Hojo

TETRAHEDRON, 65(44) 9008-9014, Oct, 2009
Rhodium-catalyzed highly enantioselective direct intermolecular hydroacylation of 1,1-disubstituted alkenes with unfunctionalized aldehydes

Yu Shibata, Ken Tanaka

Journal of the American Chemical Society, 131(35) 12552-12553, Sep 9, 2009
Rhodium-Catalyzed Highly Enantioselective Direct Intermolecular Hydroacylation of 1,1-Disubstituted Alkenes with Unfunctionalized Aldehydes

Yu Shibata, Ken Tanaka

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131(35) 12552-+, Sep, 2009
Cationic Rhodium(I)-dppf Complex-Catalyzed Olefin Isomerization/Propargyl Claisen Rearrangement/Carbonyl Migration Cascade

Ken Tanaka, Eri Okazaki, Yu Shibata

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131(31) 10822-+, Aug, 2009
Cationic Rhodium(I)-dppf Complex-Catalyzed Olefin Isomerization/Propargyl Claisen Rearrangement/Carbonyl Migration Cascade

Ken Tanaka, Eri Okazaki, Yu Shibata

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 131(31) 10822-+, Aug, 2009

Books and Other Publications

C-H Bond Formation Through Isomerization: Comprehensive Organometallic Chemistry, 3rd ed. (Mingos, D. M. P.; Crabtree, R. H.; Ojima, I. Eds.)

Elsevier (Oxford), 2007
C-H Bond Formation Through Isomerization: Comprehensive Organometallic Chemistry, 3rd ed. (Mingos, D. M. P.; Crabtree, R. H.; Ojima, I. Eds.)

Elsevier (Oxford), 2007
有機化合物の合成 V／酸化反応：ジメチルスルホキシド（DMSO）による酸化、実験化学講座第5版

丸善（東京）, 2004
有機化合物の合成 V／酸化反応：ジメチルスルホキシド（DMSO）による酸化、実験化学講座第5版

丸善（東京）, 2004

Presentations

344

カチオン性遷移金属錯体の特性を活かした触媒反応の開発

関西学院大学, 2009
企業とアカデミアの有機合成

大阪大学, 2009
不斉芳香環構築を鍵とするキラル芳香族化合物の触媒的不斉合成

東京大学, 2009
カチオン性ロジウム錯体触媒を用いたヘテロ原子架橋5?アルキナールの不斉２量化反応

日本化学会第89春期年会, 2009
カチオン性遷移金属錯体触媒を用いたπ及びσ結合の連続活性化を経由する光学活性ラクトン誘導体の合成

日本化学会第89春期年会, 2009
カチオン性ロジウム錯体触媒を用いたα,ω?ジインのカルボキシル化による高選択的環化反応

日本化学会第89春期年会, 2009
カチオン性ロジウム錯体触媒を用いた脱カルボキシル化を伴う[2 + 2 + 2]付加環化反応によるフェノール誘導体の合成

日本化学会第89春期年会, 2009
カチオン性ロジウム錯体触媒を用いた[2 + 2 + 2]付加環化反応による軸不斉ビアリールカルボン酸エステルの合成

日本化学会第89春期年会, 2009
カチオン性ロジウム錯体触媒を用いた連続[2 + 2 + 2]付加環化反応によるC2対称軸不斉ビアリールジホスフィン配位子の合成

日本化学会第89春期年会, 2009
カチオン性ロジウム錯体触媒を用いたσ及びπ結合の連続活性化を経由するアリルプロパルギルエーテルの異性化反応

日本化学会第89春期年会, 2009
カチオン性ロジウム錯体触媒を用いた1?ピロリジンカルボニル基を配向性官能基とするsp2C?H結合のアルケニル化反応

日本化学会第89春期年会, 2009
カチオン性ロジウム錯体触媒を用いた連続[2 + 2 + 2]付加環化反応による光学活性[9]ヘリセン誘導体の合成

日本化学会第89春期年会, 2009
カチオン性ロジウム錯体触媒を用いた[2 + 2 + 2]付加環化反応によるアザジベンゾフラン誘導体の合成

日本化学会第89春期年会, 2009
カチオン性ロジウム錯体触媒を用いた[2 + 2 + 2]付加環化反応による軸不斉アリールケトンの合成

日本化学会第89春期年会, 2009
アミド架橋1,5?エンインのエナンチオ選択的環化異性化反応による軸不斉4?アリール?2?ピリドン誘導体の合成

日本化学会第89春期年会, 2009
Enantioselective Synthesis of Chiral Ligands by Rhodium-Catalyzed [2 + 2 + 2] Cycloadditions

The Third Nobel Chiral Chemistries Japan (NCCJ 2009), 2009
触媒反応を利用した精密有機合成

帝人ファーマ, 2009
[2+2+2]付加環化反応を利用した新規有機発光材料の創製

JST新技術説明会, 2009
Enantioselective Lactonization of 2-Alkynylbenzaldehydes with Cyclic Dicarbonyl Compounds Catalyzed by Cationic Ag(I) and Rh(I) Complexes

15th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis（OMCOS15, Glasgow）, 2009
Highly Enantioselective Construction of Aryl-Carbonyl Axial Chirality by Rhodium-Catalyzed [2 + 2 + 2] Cycloaddition

15th IUPAC International Symposium on Organometallic Chemistry Directed Towards Organic Synthesis（OMCOS15, Glasgow）, 2009

Professional Memberships

Works

新規光学活性配位子の創製と評価

Oct, 2008 - Sep, 2010 Artistic work
新規光学活性配位子の創製と評価

Oct, 2007 - Sep, 2008 Artistic work
不斉[2+2+2]付加環化反応による新規軸不斉ビアリールホスフィン配位子の創製

Nov, 2006 - Mar, 2007 Artistic work
アルキナールの分子内ヒドロアシル化反応を経由する多官能ヘテロ環化合物の新規合成法

Aug, 2004 - Aug, 2006 Artistic work
アルキナールの分子内ヒドロアシル化反応を経由する多官能ヘテロ環化合物の新規合成法

2004 - 2006
アルキナールの分子内ヒドロアシル化反応を経由する多官能ヘテロ環化合物の新規合成法

Artistic work

Research Projects

芳香環構築による鞍型π共役分子の触媒的合成と基礎科学の開拓

科学研究費助成事業, 挑戦的研究(萌芽), 日本学術振興会, Jul, 2021 - Mar, 2023

田中健
Catalytic Asymmetric Synthesis of Belt- and Mobius-Shaped Cyclic pi-Conjugated Molecules

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (A), Japan Society for the Promotion of Science, Apr, 2019 - Mar, 2023
Helical pi-Figuration

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jul, 2014 - Mar, 2019

Tanaka Ken, Shibata Yu, Kimura Yuuki, Yamada Takayuki, Aida Yukimasa, Nishigaki Shuuhei, Terasawa Junichi, Hayase Nirihiko, Honjo Yusaku, Kinoshita Suzuka, Koshikawa Takumi, Suzuki Shunsuke, Yoshimura Ryo, Takahashi Hiroto, Tanaka Jin, Nogami Juntaro, Hanada Kyoichi, Kawasaki Kazuma, Kudo Eiji, Yamano Ryota, Satoh Masakazu, Tohriyama Shino, Heya Arisa, Bana Takafumi, Nakamura Yu, Yoshizaki Soichi, Fukui Miho, Tanaka Maya, Sakashita Kazuki, Kanno Hiroshi, Kashima Kenichi, Obata Ryosuke, Hara Junko, Yoshida Tomoka, Hara Jun, Namba Tomoya
Creation of Functionalized Cyclic Pi-Conjugated Molecules by Catalytic Aromatic Ring Construction

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Tanaka Ken
Creation of Transition-metal Complexes with Anionic Aromatic Ligands Bearing Heavy Atoms in the Skeletons

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Saito Masaichi, TANAKA Ken, NAGASE Shigeru
不活性結合活性化を鍵とする不斉触媒反応の開発

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2013 - Mar, 2015

田中健
不活性結合活性化を鍵とする不斉触媒反応の開発

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2011 - Mar, 2013

田中健
Rodium-catalyzed synthesis of organosulphur compounds

2003 - 2013
Rodium-catalyzed d-bond activation reactions

2003 - 2013
Rhodium-Catalyzed Cycloaddition Reactions

2003 - 2013
ロジウム錯体触媒を用いた有機硫黄化合物合成反応

2003 - 2013
ロジウム錯体触媒を用いたσ結合活性化反応

2003 - 2013
ロジウム錯体触媒を用いた付加環化反応

2003 - 2013
Development of Innovative Molecular Transformations Via Cationic Rhodacycles as Active Species

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (S), Japan Society for the Promotion of Science, 2008 - 2012

TANAKA Ken
可逆的配位座制御を基盤とする高効率ヒドロアシル化反応の開発

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2008 - 2009

田中健
触媒的付加環化反応による多層型シクロファン合成法の開発

科学研究費助成事業, 萌芽研究, 日本学術振興会, 2007 - 2008

田中健
不斉[2+2+2]付加環化反応による革新的軸不斉配位子合成法の開発

科学研究費助成事業, 基盤研究(B), 日本学術振興会, 2007 - 2008

田中健
可逆的配位座制御を基盤とする高効率ヒドロアシル化反応の開発

科学研究費助成事業, 特定領域研究, 日本学術振興会, 2007 - 2007

田中健
ロジウム錯体触媒を用いた光学活性メタ及びパラシクロファンの新規合成法開発

科学研究費助成事業, 若手研究(B), 日本学術振興会, 2004 - 2005

田中健
Synthesis and physical properties of new organic pi-conjugated compounds

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Misc.

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