Teppei Ikeya

Profile Information

Affiliation: associate professor (Ph.D.), Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University

J-GLOBAL ID: 201201083805762795
researchmap Member ID: B000219593

External link: http://kaken.nii.ac.jp/ja/r/30457840

Research Interests

NMR, 蛋白質立体構造解析，CYANA, NMRデータ自動解析，信号処理，分子シミュレーション

Research Areas

Research History

Oct, 2021 - Present

Associate Professor (Doctor), Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University
Apr, 2020 - Sep, 2020

Assistant Professor, Department of Chemistry, Graduate school of Science, Tokyo Metropolitan University
Apr, 2010 - Mar, 2020

Graduate School of Science and Engineering, Tokyo Metropolitan University
Apr, 2008 - Mar, 2010

Postdoctoral fellow, Institute of Biophysical Chemistry, Goethe-University Frankfurt
Apr, 2007 - Mar, 2008

Postdoctoral fellow, Department of Chemistry, Graduate School of Science, Tokyo Metropolitan University
May, 2005 - Mar, 2007

National Institute of Advanced Industrial Science and Technology
Jan, 2004 - Apr, 2005

Postdoctoral fellow, Computational Biology Research Center, National Institute of Advanced Industrial Science and Technology
Apr, 2003 - Dec, 2003

Postdoctoral fellow, Graduate School of Agricultural and Life Sciences, The University of Tokyo

Committee Memberships

Apr, 2022 - Present

評議委員, 日本核磁気共鳴学会
Apr, 2017 - Nov, 2017

Organizing committee for the 56th Annual Meeting of the NMR Society of Japan, The Nuclear Magnetic Resonance Society of Japan
Apr, 2014 - Mar, 2015

選挙管理委員会, 日本核磁気共鳴学会

Papers

Interactions of the N- and C-terminal SH3 Domains of Dro-sophila Drk with the proline-rich peptides from Sos and Dos

Sayeesh P.M, Iguchi, M, Suemoto, Y, Inoue, J, Inomata, K, Ikeya, T, Ito, Y

24 14135-14145, Sep, 2023 Peer-reviewedCorresponding author
Structural and biochemical insights into heterotetramer formation of oncogenic K-Ras4BG12V and Rgl2, a RalA/B activator

Life Science Alliance, Sep, 2023 Peer-reviewed
Structural and Functional Analyses of the Acidic and Basic Amino Acid Repeat Sequence (DDRK) in Pif 80 from Pinctada fucata on the Aragonite Crystal Surface Using NMR

Kei Futagawa, Taichi Morioka, Kazuo Furihata, Hiroyuki Watanabe, Yutaka Ito, Teppei Ikeya, Akiko Hokura, Koji Nagata, Michio Suzuki

Crystal Growth & Design, 23(7) 5264-5278, Jun 23, 2023 Peer-reviewed
Insight into the C-terminal SH3 domain mediated binding of Drosophila Drk to Sos and Dos.

Pooppadi Maxin Sayeesh, Teppei Ikeya, Haruka Sugasawa, Riki Watanabe, Masaki Mishima, Kohsuke Inomata, Yutaka Ito

Biochemical and biophysical research communications, 625 87-93, Oct 15, 2022 Peer-reviewed
Molecular mechanism of glycolytic flux control intrinsic to human phosphoglycerate kinase

Hiromasa Yagi, Takuma Kasai, Elisa Rioual, Teppei Ikeya, Takanori Kigawa

Proceedings of the National Academy of Sciences, 118(50), Dec 10, 2021 Peer-reviewed
Targeting chromosome trisomy for chromosome editing

Takuya Abe, Yuya Suzuki, Teppei Ikeya, Kouji Hirota

Scientific Reports, 11(1), Sep 10, 2021 Peer-reviewed
Multi-state structure determination and dynamics analysis reveals a new ubiquitin-recognition mechanism in yeast ubiquitin C-terminal hydrolase

Mayu Okada, Yutaka Tateishi, Eri Nojiri, Tsutomu Mikawa, Sundaresan Rajesh, Hiroki Ogasa, Takumi Ueda, Hiromasa Yagi, Toshiyuki Kohno, Takanori Kigawa …

Apr 22, 2021 Last authorCorresponding author
Paramagnetic relaxation enhancement‐assisted structural characterization of a partially disordered conformation of ubiquitin

Takuro Wakamoto, Teppei Ikeya, Soichiro Kitazawa, Nicola J. Baxter, Mike P. Williamson, Ryo Kitahara

Protein Science, 28(11) 1993-2003, Oct 18, 2019 Peer-reviewed
Protein Structure Determination in Living Cells

Teppei Ikeya, Peter Güntert, Yutaka Ito

International Journal of Molecular Sciences, 20(10) 2442-2442, May 17, 2019 Peer-reviewedLead authorCorresponding author
High-Resolution Protein 3D Structure Determination in Living Eukaryotic Cells

Takashi Tanaka, Teppei Ikeya, Hajime Kamoshida, Yusuke Suemoto, Masaki Mishima, Masahiro Shirakawa, Peter Guentert, Yutaka Ito

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 58(22) 7284-7288, May, 2019 Peer-reviewedLead authorCorresponding author
Solution NMR views of dynamical ordering of biomacromolecules

Teppei Ikeya, David Ban, Donghan Lee, Yutaka Ito, Koichi Kato, Christian Griesinger

Biochimica et Biophysica Acta (BBA) - General Subjects, 1862(2) 287-306, Feb, 2018 Peer-reviewedLead authorCorresponding author
Protein NMR Structure Refinement Based on Bayesian Inference for Dynamical Ordering of Biomacromolecules

Teppei IKEYA, Yutaka ITO

Journal of Computer Chemistry, Japan, 17(1) 65-75, 2018 Peer-reviewedLead authorCorresponding author
Advances in NMR data acquisition and processing for protein structure determination

Teppei Ikeya, Yutaka Ito

Experimental Approaches of NMR Spectroscopy: Methodology and Application to Life Science and Materials Science, 63-90, Nov 23, 2017 Peer-reviewed
Improved in-cell structure determination of proteins at near-physiological concentration

Teppei Ikeya, Tomomi Hanashima, Saori Hosoya, Manato Shimazaki, Shiro Ikeda, Masaki Mishima, Peter Güntert, Yutaka Ito

Scientific Reports, 6, Dec 2, 2016 Peer-reviewed
A specific single-stranded DNA induces a distinct conformational change in the nucleoid-associated protein HU.

Yuya Nishida, Teppei Ikeya, Tsutomu Mikawa, Jin Inoue, Yutaka Ito, Yasunori Shintani, Ryoji Masui, Seiki Kuramitsu, Seiji Takashima

Biochemistry and biophysics reports, 8 318-324, Dec, 2016 Peer-reviewed
A new carbamidemethyl-linked lanthanoid chelating tag for PCS NMR spectroscopy of proteins in living HeLa cells

Yuya Hikone, Go Hirai, Masaki Mishima, Kohsuke Inomata, Teppei Ikeya, Souichiro Arai, Masahiro Shirakawa, Mikiko Sodeoka, Yutaka Ito

JOURNAL OF BIOMOLECULAR NMR, 66(2) 99-110, Oct, 2016 Peer-reviewed
Protein NMR Structure Refinement based on Bayesian Inference

Teppei Ikeya, Shiro Ikeda, Takanori Kigawa, Yutaka Ito, Peter Güntert

Journal of Physics: Conference Series, 699(1) 012005-012005, Apr, 2016 Peer-reviewedLead authorCorresponding author
Application of Sparse Modeling to Biological NMR

Kasai, T, Ikeya, T, Kigawa, T

The Journal of the Institute of Electronics, Information and Communication Engineers, 99(5) 439-443, 2016 Peer-reviewed
Evaluation of the reliability of the maximum entropy method for reconstructing 3D and 4D NOESY-type NMR spectra of proteins

Yoshiki Shigemitsu, Teppei Ikeya, Akihiro Yamamoto, Yuusuke Tsuchie, Masaki Mishima, Brian O. Smith, Peter Guentert, Yutaka Ito

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 457(2) 200-205, Feb, 2015 Peer-reviewed
Automated resonance assignment of the 21kDa stereo-array isotope labeled thioldisulfide oxidoreductase DsbA.

Elena Schmidt, Teppei Ikeya, Mitsuhiro Takeda, Frank Löhr, Lena Buchner, Yutaka Ito, Masatsune Kainosho, Peter Güntert

Journal of magnetic resonance (San Diego, Calif. : 1997), 249 88-93, Dec, 2014

Misc.

NMR studies of a Drosophila multi-domain adaptor protein Drk

渡邉吏輝, SAYEESH Pooppadi Maxin, 末元雄介, 木川隆則, 三島正規, 猪股晃介, 池谷鉄兵, 伊藤隆

Abstracts. Annual Meeting of the NMR Society of Japan, 59th, 2020
Structural analysis of a multi-domain protein Grb2 using PRE and PCS restraints

田端真彩子, 池谷鉄兵, 美川務, 川端庸平, 安藤考史, 館野桂太, 三島正規, 伊藤隆

Abstracts. Annual Meeting of the NMR Society of Japan, 59th, 2020
in situ構造生物学による真核細胞内蛋白質の動態解明 In-cell NMRで真核細胞内蛋白質の立体構造、フォールディング安定性、ダイナミクスを解析する

伊藤隆, 田中孝, 鴨志田一, 三島正規, 池谷鉄兵, Guentert Peter

生命科学系学会合同年次大会, 2017年度 [3PW05-5], Dec, 2017
ヒト培養細胞を用いた異種核多次元in-cell NMR測定

鴨志田一, 井上仁, 猪股晃介, 池谷鉄兵, 三島正規, 伊藤隆

日本生化学会大会・日本分子生物学会年会合同大会講演要旨集, 88回・38回 [2P0384]-[2P0384], Dec, 2015
NMRデータ解析法の改良による効率的な細胞内蛋白質構造決定

池谷鉄兵, 池谷鉄兵, 花島知美, 細谷沙織, 嶋崎真那人, 池田思朗, 三島正規, 三島正規, GUENTERT Peter, GUENTERT Peter …

Abstracts. Annual Meeting of the NMR Society of Japan, 54th, 2015
Sf9細胞のin-cell NMRによる蛋白質の立体構造解析の試み

田中孝, 田中孝, 池谷鉄兵, 池谷鉄兵, 濱津順平, 三島正規, 三島正規, GUENTERT Peter, GUENTERT Peter, GUENTERT Peter …

Abstracts. Annual Meeting of the NMR Society of Japan, 54th, 2015
3P080 A refinement method for NMR protein structure determination based on Bayesian inference(01E. Protein: Measurement & Analysis,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

Ikeya Teppei, Ito Yutaka, Peter Guentert

Seibutsu Butsuri, 54(1) S262, 2014
1SDP-04 Dynamics of intrinsically disordered proteins in living cells(1SDP Protein Dynamics and Function in Cells elucidated by in-cell NMR and High Performance Computing,Symposium,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

Ikeya Teppei, Inoue Jin, Ito Yutaka

Seibutsu Butsuri, 54(1) S123, 2014
1P080 Effect of basis selection in reconstructing NMR spectra using compressed sensing(01E. Protein : Measurement & Analysis,Poster,The 52nd Annual Meeting of the Biophysical Society of Japan(BSJ2014))

Sumikoshi Kazuya, Ikeya Teppei, Ito Yutaka, Shimizu Kentaro

Seibutsu Butsuri, 54(1) S154, 2014
NMR蛋白質立体構造決定のための新規構造最適化法の開発

嶋崎真那人, 池谷鉄兵, 三島正規, 伊藤隆, GUENTERT Peter, GUENTERT Peter

Abstracts. Annual Meeting of the NMR Society of Japan, 52nd, 2013
3P010 Development of a new refinement method for NMR protein structure determination(01A. Protein: Structure,Poster)

Shimazaki Manato, Ikeya Teppei, Mishima Masaki, Ito Yutaka, Guentert Peter

Seibutsu Butsuri, 53(1) S213, 2013
2P078 Reconstruction of NMR spectra using compressed sensing(01E. Protein: Measurement & Analysis,Poster)

Sumikoshi Kazuya, Ikeya Teppei, Ito Yutaka, Shimizu Kentaro

Seibutsu Butsuri, 53(1) S171, 2013

Professional Memberships

Apr, 2012 - Present

電気情報通信学会
Apr, 2003 - Present

日本核磁気共鳴学会
Apr, 2002 - Present

日本生物物理学会

Research Projects

Ensemble structure determination using multiple measurement data in solution state

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2021 - Mar, 2024
Development of siginal processing and proten structure determination methods for low qulaity NMR data

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

IKEYA Teppei
Enabling NMR studies of sparsely labelled large proteins by automated assignment

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2017 - Mar, 2020

Guentert Peter
生細胞内の秩序と蛋白質構造安定性の解明に向けた基盤技術

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2016 - Mar, 2018

池谷鉄兵
Development of NMR data analysis methods for proten three-dimensional structure

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

IKEYA TEPPEI, ITO Yutaka, GUENTERT Peter
Initiative for faster and more precise NMR data measurement and analysis with sparse modeling

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research on Innovative Areas (Research in a proposed research area), Japan Society for the Promotion of Science, Jun, 2013 - Mar, 2018

Kigawa Takanori, Kasai Takuma
生細胞内の秩序構造が誘起する蛋白質立体構造の安定性

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2014 - Mar, 2016

池谷鉄兵
Optimization of automated NMR data analysis for in-cell NMR structure determination

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2016

Peter Guentert, Ikeya Teppei, Ito Yutaka
New NMR data analysis and signal processing methods for in-cell NMR

Grants-in-Aid for Scientific Research, Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2012 - Mar, 2015

IKEYA Teppei, ITO Yutaka, GUENTERT Peter
天然変性蛋白質の細胞内解析に向けたペプチド分子のｉｎ‐ＣｅｌｌＮＭＲ計測

科学研究費助成事業, 新学術領域研究(研究領域提案型), 日本学術振興会, Apr, 2012 - Mar, 2014

池谷鉄兵
Towards generalized structure determination of in-cell NMR using the fully automated structure analysis

Grants-in-Aid for Scientific Research, Grant-in-Aid for Research Activity Start-up, Japan Society for the Promotion of Science, 2010 - 2011

IKEYA Teppei

Profile Information

Research Interests

Research Areas

Research History

Committee Memberships

Papers

Misc.

Professional Memberships

Research Projects

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