大植隆司 (Ryuji Ohue) - マイポータル

基本情報

所属: 京都大学

学位: 博士（農学）(京都大学)

J-GLOBAL ID: 201901000129536182
researchmap会員ID: B000377561

研究分野

ライフサイエンス / 分子生物学 /

論文

Differential effects of sodium-glucose cotransporter 2 inhibitor and low-carbohydrate diet on body composition and metabolic profile in obese diabetic db/db mice

Toru Kusakabe, Shigefumi Yokota, Mika Shimizu, Takayuki Inoue, Masashi Tanaka, Ryuji Ohue-Kitano, Kazuya Muranaka, Hajime Yamakage, Hiromichi Wada, Koji Hasegawa, Noriko Satoh-Asahara

BMJ Open Diabetes Research & Care 8(1) e001303-e001303 2020年9月査読有り
Maternal gut microbiota in pregnancy influences offspring metabolic phenotype in mice

Ikuo Kimura, Junki Miyamoto, Ryuji Ohue-Kitano, Keita Watanabe, Takahiro Yamada, Masayoshi Onuki, Ryo Aoki, Yosuke Isobe, Daiji Kashihara, Daisuke Inoue, Akihiko Inaba, Yuta Takamura, Satsuki Taira, Shunsuke Kumaki, Masaki Watanabe, Masato Ito, Fumiyuki Nakagawa, Junichiro Irie, Hiroki Kakuta, Masakazu Shinohara, Ken Iwatsuki, Gozoh Tsujimoto, Hiroaki Ohno, Makoto Arita, Hiroshi Itoh, Koji Hase

Science 367(6481) eaaw8429-eaaw8429 2020年2月28日査読有り
Free Fatty Acid Receptors in Health and Disease.

Ikuo Kimura, Atsuhiko Ichimura, Ryuji Ohue-Kitano, Miki Igarashi

Physiological reviews 100(1) 171-210 2020年1月1日査読有り
Dietary short-chain fatty acid intake improves the hepatic metabolic condition via FFAR3

Hidenori Shimizu, Yuki Masujima, Chihiro Ushiroda, Rina Mizushima, Satsuki Taira, Ryuji Ohue-Kitano, Ikuo Kimura

Scientific Reports 9(1) 16574 2019年12月査読有り
Ketone body receptor GPR43 regulates lipid metabolism under ketogenic conditions

Junki Miyamoto, Ryuji Ohue-Kitano, Hiromi Mukouyama, Akari Nishida, Keita Watanabe, Miki Igarashi, Junichiro Irie, Gozoh Tsujimoto, Noriko Satoh-Asahara, Hiroshi Itoh, Ikuo Kimura

Proceedings of the National Academy of Sciences 116(47) 23813-23821 2019年11月19日査読有り筆頭著者
Regulation of host energy metabolism by gut microbiota-derived short-chain fatty acids

Hidenori Shimizu, Ryuji Ohue-Kitano, Ikuo Kimura

Glycative Stress Research 6(3) 181-191 2019年9月査読有り
3-(4-Hydroxy-3-methoxyphenyl)propionic Acid Produced from 4-Hydroxy-3-methoxycinnamic Acid by Gut Microbiota Improves Host Metabolic Condition in Diet-Induced Obese Mice

Ryuji Ohue-Kitano, Satsuki Taira, Keita Watanabe, Yuki Masujima, Toru Kuboshima, Junki Miyamoto, Yosuke Nishitani, Hideaki Kawakami, Hiroshige Kuwahara, Ikuo Kimura

Nutrients 11(5) 1036-1036 2019年5月9日査読有り筆頭著者責任著者
Serum soluble TREM2 is a potential novel biomarker of cognitive impairment in Japanese non-obese patients with diabetes

M. Tanaka, H. Yamakage, S. Masuda, T. Inoue, R. Ohue-Kitano, R. Araki, Y. Matoba, M. Saito, T. Nagaoka, K. Yonezawa, T. Tanaka, M. Suzuki, M. Sawamura, M. Nishimura, S. Odori, H. Wada, K. Kotani, T. Kusakabe, A. Shimatsu, K. Hasegawa, N. Satoh-Asahara

Diabetes & Metabolism 45(1) 86-89 2019年1月査読有り
Role of serum myostatin in the association between hyperinsulinemia and muscle atrophy in Japanese obese patients

Masashi Tanaka, Shinya Masuda, Hajime Yamakage, Takayuki Inoue, Ryuji Ohue-Kitano, Shigefumi Yokota, Toru Kusakabe, Hiromichi Wada, Kiyoshi Sanada, Kojiro Ishii, Koji Hasegawa, Akira Shimatsu, Noriko Satoh-Asahara

Diabetes Research and Clinical Practice 142 195-202 2018年8月査読有り
Chemokine (C-X-C motif) ligand 1 is a myokine induced by palmitate and is required for myogenesis in mouse satellite cells

S. Masuda, M. Tanaka, T. Inoue, R. Ohue-Kitano, H. Yamakage, K. Muranaka, T. Kusakabe, A. Shimatsu, K. Hasegawa, N. Satoh-Asahara

Acta Physiologica 222(3) e12975-e12975 2018年3月査読有り
α‐Linolenic acid‐derived metabolites from gut lactic acid bacteria induce differentiation of anti‐inflammatory M2 macrophages through G protein‐coupled receptor 40

Ryuji Ohue‐Kitano, Yumiko Yasuoka, Tsuyoshi Goto, Nahoko Kitamura, Si‐Bum Park, Shigenobu Kishino, Ikuo Kimura, Mayu Kasubuchi, Haruya Takahashi, Yongjia Li, Yu‐Sheng Yeh, Huei‐Fen Jheng, Mari Iwase, Masashi Tanaka, Shinya Masuda, Takayuki Inoue, Hajime Yamakage, Toru Kusakabe, Fumito Tani, Akira Shimatsu, Nobuyuki Takahashi, Jun Ogawa, Noriko Satoh‐Asahara, Teruo Kawada

The FASEB Journal 32(1) 304-318 2018年1月査読有り筆頭著者
10‐oxo‐12(Z)‐octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, enhances energy metabolism by activation of TRPV1

Minji Kim, Tomoya Furuzono, Kanae Yamakuni, Yongjia Li, Young‐Il Kim, Haruya Takahashi, Ryuji Ohue‐Kitano, Huei‐Fen Jheng, Nobuyuki Takahashi, Yuriko Kano, Rina Yu, Shigenobu Kishino, Jun Ogawa, Kunitoshi Uchida, Jun Yamazaki, Makoto Tominaga, Teruo Kawada, Tsuyoshi Goto

The FASEB Journal 31(11) 5036-5048 2017年11月査読有り
Prediction of functional profiles of gut microbiota from 16S rRNA metagenomic data provides a more robust evaluation of gut dysbiosis occurring in Japanese type 2 diabetic patients

Inoue Ryo, Ohue-Kitano Ryuji, Tsukahara Takamitsu, Tanaka Masashi, Masuda Shinya, Inoue Takayuki, Yamakage Hajime, Kusakabe Toru, Hasegawa Koji, Shimatsu Akira, Satoh-Asahara Noriko

ＪｏｕｒｎａｌｏｆＣｌｉｎｉｃａｌＢｉｏｃｈｅｍｉｓｔｒｙａｎｄＮｕｔｒｉｔｉｏｎ 61(3) 217-221 2017年11月査読有り筆頭著者
Synthesized enone fatty acids resembling metabolites from gut microbiota suppress macrophage-mediated inflammation in adipocytes

Ha-Eun Yang, Yongjia Li, Akira Nishimura, Huei-Fen Jheng, Ana Yuliana, Ryuji Kitano-Ohue, Wataru Nomura, Nobuyuki Takahashi, Chu-Sook Kim, Rina Yu, Nahoko Kitamura, Si-Bum Park, Shigenobu Kishino, Jun Ogawa, Teruo Kawada, Tsuyoshi Goto

Molecular Nutrition & Food Research 61(10) 1700064-1700064 2017年10月査読有り
Omega-3 polyunsaturated fatty acids suppress the inflammatory responses of lipopolysaccharide-stimulated mouse microglia by activating SIRT1 pathways

Takayuki Inoue, Masashi Tanaka, Shinya Masuda, Ryuji Ohue-Kitano, Hajime Yamakage, Kazuya Muranaka, Hiromichi Wada, Toru Kusakabe, Akira Shimatsu, Koji Hasegawa, Noriko Satoh-Asahara

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids 1862(5) 552-560 2017年5月査読有り
A Novel TREM2-Mediated Link between Diabetes and Cognitive Impairment: Recent Findings and Future Perspectives

Masashi Tanaka, Hajime Yamakage, Takayuki Inoue, Shinya Masuda, Ryuji Ohue-Kitano, Toru Kusakabe, Noriko Satoh-Asahara

Journal of Alzheimer’s Disease & Parkinsonism 7(5) 2017年査読有り
10-oxo-12(Z)-octadecenoic acid, a linoleic acid metabolite produced by gut lactic acid bacteria, potently activates PPARγ and stimulates adipogenesis

Tsuyoshi Goto, Young-Il Kim, Tomoya Furuzono, Nobuyuki Takahashi, Kanae Yamakuni, Ha-Eun Yang, Yongjia Li, Ryuji Ohue, Wataru Nomura, Tatsuya Sugawara, Rina Yu, Nahoko Kitamura, Si-Bum Park, Shigenobu Kishino, Jun Ogawa, Teruo Kawada

Biochemical and Biophysical Research Communications 459(4) 597-603 2015年4月査読有り
Changes in lamina propria dendritic cells on the oral administration of exogenous protein antigens during weaning

Ryuji Ohue, Masahiro Nakamoto, Naofumi Kitabatake, Fumito Tani

Cytotechnology 64(3) 221-230 2012年5月査読有り筆頭著者
Bacterial Heat Shock Protein 60, GroEL, Can Induce the Conversion of Naïve T Cells into a CD4+ CD25+ Foxp3-Expressing Phenotype

Ryuji Ohue, Kei Hashimoto, Masahiro Nakamoto, Yuichi Furukawa, Tetsuya Masuda, Naofumi Kitabatake, Fumito Tani

Journal of Innate Immunity 3(6) 605-613 2011年査読有り筆頭著者
Effects of CpG- oligodeoxynucleotides on dendritic cell development

R. Ohue, F. Tani, N. Kitabatake

Nucleic Acids Symposium Series 52(1) 647-648 2008年9月1日査読有り筆頭著者

MISC

ケトン体受容体による生体機能制御

大植隆司, 西田朱里, 木村郁夫

医学のあゆみ 276(12) 1098-1103 2021年筆頭著者
腸内細菌と肥満症

大植隆司, 加藤裕教, 木村郁夫

実験医学（増刊号） 39(5) 188-194 2021年筆頭著者
低炭水化物食における分子栄養メカニズム

西田朱里, 宮本潤基, 大植隆司, 木村郁夫

Pharma Medica 38(9) 79-83 2020年
腸内細菌代謝物と生体機能—循環器・代謝疾患の治療への応用—

清水秀憲, 大植隆司, 木村郁夫

CARDIAC PRACTICE 29(4) 23-27 2019年
肥満症・2型糖尿病とプロバイオティクス

大植隆司, 平さつき, 木村郁夫

臨床と研究 95(9) 51-56 2018年筆頭著者
食物繊維由来腸内細菌代謝物、短鎖脂肪酸と宿主代謝制御

平さつき, 渡辺啓太, 大植隆司, 木村郁夫

ルミナコイド研究 22(2) 53-62 2018年
腸内細菌と食事療法

浅原哲子, 北野隆司

月刊糖尿病 9(5) 43-56 2017年
肥満症における腸内細菌とエクオールの関与

浅原哲子, 北野隆司

内分泌・糖尿病・代謝内科 45(1) 14-21 2017年

書籍等出版物

腸内微生物叢最前線

大植隆司, 清水秀憲, 木村郁夫 (担当:共著)

2021年
食品機能性脂質の基礎と応用

大植隆司, 平さつき, 木村郁夫 (担当:共著)

2018年