論文

査読有り
2010年1月

PC3 is involved in the shift from proliferation to differentiation and maturation in spiral ganglion neurons

NEUROREPORT
  • Momoko Hayashida
  • ,
  • Ryosei Minoda
  • ,
  • Yohei Shinmyo
  • ,
  • Kunimasa Ohta
  • ,
  • Hideaki Tanaka
  • ,
  • Eiji Yumoto

21
2
開始ページ
90
終了ページ
93
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1097/WNR.0b013e328332c4d7
出版者・発行元
LIPPINCOTT WILLIAMS & WILKINS

PC3 is a member of the BTG/Tob family of antiproliferative genes. Here, we report the results of an analysis of PC3 protein expression in spiral ganglion neurons of the rat cochlea at embryonic days 16 (E16) and 20 (E20), and postnatal days 4 (P4) and 7 (P7). PC3 expression was observed in the cytoplasm of ganglion neurons at Ell 6 and E20, and this protein had translocated to the nucleus by P4. The expression of Ki-67, a nuclear antigen expressed by dividing cells, was detected in ganglion neurons at E16 and E20, but not at P4 or P7. These results suggest that PC3 is involved in the shift from proliferation to differentiation and maturation in the ganglion neurons of the rat cochlea. NeuroReport 21:90-93 (C) 2010 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.

Web of Science ® 被引用回数 : 1

リンク情報
DOI
https://doi.org/10.1097/WNR.0b013e328332c4d7
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/19997037
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000273928600003&DestApp=WOS_CPL

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