論文

査読有り 国際誌
2019年11月

How did a duplicated gene copy evolve into a restorer-of-fertility gene in a plant? The case of Oma1.

Royal Society open science
  • Takumi Arakawa
  • ,
  • Hajime Sugaya
  • ,
  • Takaya Katsuyama
  • ,
  • Yujiro Honma
  • ,
  • Katsunori Matsui
  • ,
  • Hiroaki Matsuhira
  • ,
  • Yosuke Kuroda
  • ,
  • Kazuyoshi Kitazaki
  • ,
  • Tomohiko Kubo

6
11
開始ページ
190853
終了ページ
190853
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1098/rsos.190853

Restorer-of-fertility (Rf) is a suppressor of cytoplasmic male sterility (CMS), a mitochondrion-encoded trait that has been reported in many plant species. The occurrence of CMS is considered to be independent in each lineage; hence, the question of how Rf evolved was raised. Sugar beet Rf resembles Oma1, a gene for quality control of the mitochondrial inner membrane. Oma1 homologues comprise a small gene family in the sugar beet genome, unlike Arabidopsis and other eukaryotes. The sugar beet sequence that best matched Arabidopsis atOma1 was named bvOma1; sugar beet Rf (RF1-Oma1) was another member. During anther development, atOma1 mRNA was detected from the tetrad to the microspore stages, whereas bvOma1 mRNA was detected at the microspore stage and RF1-Oma1 mRNA was detected during the meiosis and tetrad stages. A transgenic study revealed that, whereas RF1-Oma1 can bind to a CMS-specific protein and alter the higher-order structure of the CMS-specific protein complex, neither bvOma1 nor atOma1 show such activity. We favour the hypothesis that an ancestral Oma1 gene duplicated to form a small gene family, and that one of the copies evolved and acquired a novel expression pattern and protein function as an Rf, i.e. RF1-Oma1 evolved via neofunctionalization.

リンク情報
DOI
https://doi.org/10.1098/rsos.190853
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31827833
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894571

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