礒川昌子 (Isokawa Masako) - マイポータル

基本情報

所属: 大阪大学基礎理学プロジェクト研究センター招へい研究員

学位: 学術博士(大阪大学)
Ph.D.(Institute of Animal Behaviour-Rutgers)

J-GLOBAL ID: 201901007207729850
researchmap会員ID: B000366631

1984-2000 Research Neurologist, Brain Research Institute, University of California Los Angeles
2000-2001 Associate Research Scientist, Department of Neurological Surgery, Columbia University College of Physicians & Surgeons, New York, NY
2001-2005 Assistant Professor, Department of Physiology, University of Maryland, Baltimore
2005-2014 Associate Professor, Department of Biological Sciences, University of Texas at Brownsville
2014-2018 Professor, Department of Health and Biomedical Sciences, University of Texas Rio Grande Valley
2019-2022 大阪大学大学院理学研究科付属基礎理学プロジェクト研究センター

2022-present 大阪大学大学院理学研究科付属フォアフロントリサーチセンター

研究キーワード

研究分野

経歴

2022年4月 - 現在

大阪大学大学院理学研究科フォアフロントリサーチセンター, 招聘研究員
2019年7月 - 現在

大阪大学, 基礎理学プロジェクト研究センター, 招へい研究員
2014年 - 2018年

University of Texas Rio Grande Valley, Dept. Health & Biomedical Sciences, Professor
2005年 - 2014年

University of Texas Brownsville, Dept. Biomedical Sciences, Associate Professor
2001年 - 2005年

University of Maryland Baltimore, Dept. Physiology, Assistant Professor
2000年 - 2001年

Columbia Uiversity, College of Physicians & Surgeons, Associate Research Scientist
1993年 - 2000年

University of California Los Angeles, Brain Research Institute, Principal Investigator for R29 "Excitability of degenerating neurons in epilepsy"
1988年 - 1993年

University of California Los Angeles, Brain Research Institute, Principal Investigator for PO1 "In Vitro Physiology" (Program Director: P. Crandal)

学歴

委員歴

2013年9月 - 2017年4月

National Science Foundation, Panel of Graduate Research Fellowship Program
2014年2月 - 2014年11月

National Institute of Health, Special Emphasis Panel DZA1
2006年5月 - 2013年4月

Alzheimer's Association, Research Review Committee (Field)

受賞

2013年2月

Academic Research Enhancement (AREA) Award, Cannabinoid Mobilization in Neurons, National Institute of Drug Abuse

Masako Isokawa
2008年2月

Academic Research Enhancement (AREA) Award, Cannabinoid Mobilization in Neurons, National Institute of Health

Masako Isokawa
2007年8月

Borderplex Council Award, Neural mechanisms underlying obesity, University of Texas System

Masako Isokawa
1993年8月

First Independent Research Support and Transition (FIRST) Awards, Excitability of Degenerating Neurons in Epilepsy, National Institute of Health

Masako Isokawa

論文

Large-Scale Multi-Omic Approaches and Atlas-Based Profiling for Cellular, Molecular, and Functional Specificity, Heterogeneity, and Diversity in the Endocannabinoid System

Jun Aoki, Masako Isokawa

Cells 12(5) 814-814 2023年3月6日招待有り
Space and Time Coherent Mapping for Subcellular Resolution of Imaging Mass Spectrometry

Jun Aoki, Masako Isokawa, Michisato Toyoda

Cells 11(21) 3382-3382 2022年10月26日査読有り招待有り
Imaging Endocannabinoids and Bioactive Lipid Messengers in Basic Research and Biomedical Application

Jun Aoki, Masako Isokawa

Cells 11(11) 1756-1756 2022年5月26日査読有り招待有り
Ghrelin-O-acyltransferase acylates ghrelin in the hippocampus

Isokawa Masako

Vitamins and Hormones 118 2021年査読有り筆頭著者責任著者
Endogenous ghrelin-O-acyltransferase (GOAT) acylates local ghrelin in the hippocampus

Murtuza MI, Isokawa M

J. Neurochemistry 144 58-67 2018年査読有り
Ghrelin phosphorylates GluN2B Subunit of the NMDA receptor by activating GHSR1a and Fyn in the Rat Hippocampus

Berrout L, Isokawa M

Brain Research 1678 20-26 2018年査読有り
Caffeine-Induced Suppression of GABAergic Inhibition and Calcium-Independent Metaplasticity

Masako Isokawa

NEURAL PLASTICITY Article ID 1239629 2016年査読有り
Ghrelin receptor activity amplifies hippocampal N-methyl-D-aspartate receptor-mediated postsynaptic currents and increases phosphorylation of the GluN1 subunit at Ser896 and Ser897

Brandon G. Muniz, Masako Isokawa

EUROPEAN JOURNAL OF NEUROSCIENCE 42(12) 3045-3053 2015年12月査読有り
Ghrelin promotes reorganization of dendritic spines in cultured rat hippocampal slices

Liza Berrout, Masako Isokawa

NEUROSCIENCE LETTERS 516(2) 280-284 2012年5月査読有り
Cellular Signal Mechanisms of Reward-Related Plasticity in the Hippocampus

Masako Isokawa

NEURAL PLASTICITY Article ID 945373 2012年査読有り
Ghrelin-induced activation of cAMP signal transduction and its negative regulation by endocannabinoids in the hippocampus

Jacquelynn N. Cuellar, Masako Isokawa

NEUROPHARMACOLOGY 60(6) 842-851 2011年5月査読有り
Homeostatic and stimulus-induced coupling of the L-type Ca2+ channel to the ryanodine receptor in the hippocampal neuron in slices

Jonathan Berrout, Masako Isokawa

CELL CALCIUM 46(1) 30-38 2009年7月査読有り
Time-dependent induction of CREB phosphorylation in the hippocampus by the endogenous cannabinoid

Masako Isokawa

NEUROSCIENCE LETTERS 457(1) 53-57 2009年6月査読有り
Metabolic demand stimulates CREB signaling in the limbic cortex: Implication for the induction of hippocampal synaptic plasticity by intrinsic stimulus for survival.

Estrada NM, Isokawa M

Front. Syst. Neurosci doi:10.3389/neuro.06.005.2009 2009年査読有り
Ryanodine receptor regulates endogenous cannabinoid mobilization in the hippocampus

M Isokawa, BE Alger

JOURNAL OF NEUROPHYSIOLOGY 95(5) 3001-3011 2006年5月査読有り
Retrograde endocannabinoid regulation of GABAergic inhibition in the rat dentate gyrus granule cell

M Isokawa, BE Alger

JOURNAL OF PHYSIOLOGY-LONDON 567(3) 1001-1010 2005年9月査読有り
N-methyl-D-aspartic acid-induced and Ca-dependent neuronal swelling and its retardation by brain-derived neurotrophic factor in the epileptic hippocampus

M Isokawa

NEUROSCIENCE 131(4) 801-812 2005年査読有り
NMDA-induced and Ca-dependent neuronal swelling and its retardation with BDNF in the epileptic hippocampus.

Isokawa, M

Neuroscience 131 108-112 2005年査読有り
Electrophysiological and morphological properties of dentate glia in the rat hippocampus.

Isokawa M, McKhann GM

J. Neurobiology 65 125-134 2005年査読有り
Activation of muscarinic acetylcholine receptors enhances the release of endogenous cannabinoids in the hippocampus

J Kim, M Isokawa, C Ledent, BE Alger

JOURNAL OF NEUROSCIENCE 22(23) 10182-10191 2002年12月査読有り

もっとみる

MISC

Activation of the Ghrelin Receptor Mediates NMDA Receptor Phosphorylation at the NR1 Subunit in the Rat Hippocampus

Brandon Muniz, Masako Isokawa

FASEB JOURNAL 29 2015年4月
Effect of ghrelin on the regulation of dendritic spines in the rat hippocampus

Jacquelynn Nicole Cuellar, Liza Berrout, Masako Isokawa

FASEB JOURNAL 25 2011年4月
Expression of phosphorylated CREB in the fasted rat hippocampus

Nelly M. Estrada, Masako Isokawa

FASEB JOURNAL 23 2009年4月
Ryanodine receptor regulates endogenous cannabinoid mobilization in the hippocampus (vol 95, pg 3001, 2006)

M. Isokawa, B. E. Alger

JOURNAL OF NEUROPHYSIOLOGY 96(2) 965-965 2006年8月
Endocannabinoids and the regulation of synaptic inhibition

BE Alger, M Isokawa, J Kim

JOURNAL OF NEUROCHEMISTRY 85 29-29 2003年5月
Developmental changes in NMDA-induced intrinsic optical signals in the hippocampal dentate gyrus of children with medically-intractable seizures.

M Isokawa, GW Mathern

EPILEPSIA 40 25-25 1999年
Preservation of dendrites with the presence of reorganized mossy fiber collaterals in hippocampal dentate granule cells in patients with temporal lobe epilepsy (vol 744, pg 339, 1997)

M Isokawa

BRAIN RESEARCH 758(1-2) 263-263 1997年5月
PREICTAL AND POSTICTAL NEURONAL DISCHARGE PATTERNS IN COMPLEX PARTIAL EPILEPSY PATIENTS

CL WILSON, M ISOKAWAAKESSON, TL BABB, J ENGEL

EPILEPSIA 27(5) 637-637 1986年9月
LACK OF FUNCTIONAL EVIDENCE FOR A HUMAN HIPPOCAMPAL COMMISSURE

CL WILSON, M ISOKAWAAKESSON, ML WANG, TL BABB, J ENGEL

ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY 61(3) S54-S55 1985年

書籍等出版物

Vitamines and Hormons: Hormons in the Hippocampus

Masako Isokawa (担当:共著, 範囲:GOAT acrylates ghrelin in the hippocampus)

Elsevier 2021年
Synaptic plasticity” (ISBN 978-953-51-5036-7).

T Heinbockel, Isokawa M (担当:分担執筆, 範囲:The Ghrelin Receptor Regulates Dendritic Spines and the NMDA Receptor-mediated Synaptic Transmission in the Hippocampus)

InTech 2017年
Physiology of hippocampal neurons in humans and lower mammals.

Isokawa-Akesson, M, Wilson, C.L, Babb, T.L (担当:分担執筆, 範囲:In: J. Engel, Jr., Ojemann, G.A., Luders H.O., and Williamson, P.D. (Eds.), "Fundamental Mechanisms of Human Brain Function)

Raven Press, New York 1987年
A comparative view of local and interhemispheric limbic pathways in humans: an evoked potential analysis

Wilson, C.L, Isokawa-Akesson, M, Babb.T.L (担当:分担執筆, 範囲:In: J. Engel, Jr.,Ojemann, G.A., Luders, H.O., and Williamson, P.D.(Eds.), "Fundamental Mechanisms of Human Brain Function: Surgical Treatment of Epilepsy as an Investigative Resource)

Raven Press, New York 1987年

担当経験のある科目(授業)

所属学協会

共同研究・競争的資金等の研究課題

Cannabinoid mobilization in neurons II

National Institute of Health (NIH NIDA) R15 2013年2月 - 2017年4月

Masako Isokawa
Caffeine-induced modulation of GABAergic transmission

National Institute of Health (NIH NIGMS) SC1 2003年9月 - 2014年8月

Masako Isokawa
Cannabinoid mobilization in neurons

National Institute of Health (NIH NIDA) R15 2008年2月 - 2013年1月

Masako Isokawa
Creation of Hispnic Research Center - Learning and Addiction

National Institute of Health (NIH NIGMS) P20 2006年3月 - 2008年2月

J McCormic, M. Isokawa
Developping Medical Research Infrastructure-Hippocampal slice culture model of addiction

National Institute of Health (NIH NIGMS) P20 2006年7月 - 2007年10月

JG Martin, M. Isokawa
Endocannabinoids and the GABAergic control of plasticity

National Institute of Health (NIH NIDA) R01 2001年9月 - 2006年6月

B.E. Alger, M. Isokawa
Endocannabinoid: A self-defense mechanism for stroke

University of Maryland Cigarette Smoking Recessitation Funds 2004年7月 - 2005年6月

Masako Isokawa
Modulation of endocannabinoid release by intracellular calcium

University of Maryland Bressler Research Fund 2002年7月 - 2003年6月

Masako Isokawa
Excitability of degenerating neurons in epilepsy

National Institute of Health (NIH NINDA) R29 1993年8月 - 2000年7月

Masako Isokawa
Clinical Reserch Program-In Vitro Pathophysiology

National Institute of Health (NIH NINDA) PO1 1995年6月 - 2000年5月

J Engel, Jr, M. Isokawa
Clinical Reserch Program - In Vito Pathophysiology

National Institute of Health (NIH NINDA) PO1 1990年4月 - 1995年3月

J. Engel Jr, M. Isokawa