Makoto Kawatani

Last updated: Oct 11, 2018 at 08:42

Name	Makoto Kawatani
E-mail	mkawataniriken.jp

Research Interests

Bone disease(3) , Cancer(362) , Bioactive compound(16) , Chemical biology(135)

Research Areas

Biomolecular science / Biomolecular chemistry /
Biomolecular science / Chemical biology /

Academic & Professional Experience

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Apr 2012

Today

Senior Research Scientist, Chemical Biology Research Group, RIKEN Center for Sustainable Resource Science (CSRS)

Apr 2009

Mar 2012

Scientist, Antibiotics Laboratory, RIKEN ASI

Apr 2007

Mar 2009

Postdoctoral Researcher, Antibiotics Laboratory, RIKEN DRI

Apr 2004

Mar 2007

Special Postdoctoral Researcher, Antibiotics Laboratory, RIKEN DRI

Apr 2003

Mar 2004

Postdoctral Researcher, Antibiotics Laboratory, RIKEN DRI

Education

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Apr 2000

Mar 2003

School of Fundamental Science and Technology, Faculty of Science and Technology, Keio University

Apr 1998

Mar 2000

Department of Biomedical Engineering, Graduate School of Science and Technology, Keio University

Mar 1998

Department of Applied Chemistry, Faculty of Science and Technology, Keio University

Awards & Honors

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2012

The Young Investigator Awards of the Japanese Cancer Association, The Japanese Cancer Association

2009

RIKEN Research Incentive Award, RIKEN

2009

The Excellent Paper Award Published in Bioscience, Biotechnology, & Biochemistry, The Japan Society for Bioscience, Biotechnology, and Agrochemistry

2009

The Young Investigator Award of the Japanese Association for Molecular Target Therapy of Cancer, The Japanese Association for Molecular Target Therapy of Cancer

2007

The Excellent Paper Award Published in Bioscience, Biotechnology, & Biochemistry, The Japan Society for Bioscience, Biotechnology, and Agrochemistry

Published Papers

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Bioenergetic and proteomic profiling to screen small molecule inhibitors that target cancer metabolisms.

Futamura Y, Muroi M, Aono H, Kawatani M, Hayashida M, Sekine T, Nogawa T, Osada H

Biochimica et biophysica acta. Proteins and proteomics Jun 2018 [Refereed]

Identification and structure-activity relationship of purine derivatives as novel MTH1 inhibitors.

Kumar A, Kawamura T, Kawatani M, Osada H, Zhang KYJ

Chemical biology & drug design 89(6) 862-869 Jun 2017 [Refereed]

Actin-binding protein coronin 1A controls osteoclastic bone resorption by regulating lysosomal secretion of cathepsin K.

Ohmae S, Noma N, Toyomoto M, Shinohara M, Takeiri M, Fuji H, Takemoto K, Iwaisako K, Fujita T, Takeda N, Kawatani M, Aoyama M, Hagiwara M, Ishihama Y, Asagiri M

Scientific reports 7 41710 Mar 2017 [Refereed]

Structure‐activity relationships of terpendole E and its natural derivatives.

Nagumo Y., Motoyama T., Hayashi T., Hirota H., Aono H., Kawatani M., Osada H., and Usui T.

Chemistry Select 2 1533-1536 2017 [Refereed]

Proteomic profiling reveals that collismycin A is an iron chelator.

Kawatani M, Muroi M, Wada A, Inoue G, Futamura Y, Aono H, Shimizu K, Shimizu T, Igarashi Y, Takahashi-Ando N, Osada H

Scientific reports 6 38385 Dec 2016 [Refereed]

Association Memberships

JAPANESE SOCIETY FOR CHEMICAL BIOLOGY(172) , JAPAN SOCIETY FOR BIOSCIENCE, BIOTECHNOLOGY, AND AGROCHEMISTRY(734) , THE JAPANESE ASSOCIATION FOR MOLECULAR TARGET THERAPY OF CANCER(152) , THE JAPANESE CANCER ASSOCIATION(1398)