論文

査読有り
2015年8月

Paradental cyst is an inclusion cyst of the junctional/sulcular epithelium of the gingiva: histopathologic and immunohistochemical confirmation for its pathogenesis

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY
  • Satoshi Maruyama
  • ,
  • Manabu Yamazaki
  • ,
  • Tatsuya Abe
  • ,
  • Hamzah Babkair
  • ,
  • Jun Cheng
  • ,
  • Takashi Saku

120
2
開始ページ
227
終了ページ
237
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.oooo.2015.04.001
出版者・発行元
ELSEVIER SCIENCE INC

Objective. The aim of this study was to characterize the histologic and immunohistochemical profiles of paradental cystlining epithelia to clarify its histopathogenesis.
Study Design. Ten surgical specimens of paradental cysts were examined for clinical profiles and to determine the histopathologic characteristics of the lining epithelia. Immunohistochemical profiles for keratin (K) subtypes, as well as for perlecan, UEA-I lectin binding, and proliferating cell nuclear antigen (PCNA), were determined and compared.
Results. The paradental cyst was clinically characterized by its occurrence in young adults (mean age, 36.8 years; male, 42.8, female 27.8). Eight of the 10 cases arose in the retromolar area. The cyst wall was basically granulation tissue that was attached to the periodontal ligament space. Thin irregular anastomosing epithelial cords lined the cyst walls of immature granulation tissue with vascular dilation and hemorrhage. The intercellular space of the lining epithelia was widened with inflammatory cell infiltrates. Immunohistochemically, the lining was positive for K13, K14, K17, K19, UEA-I binding, and perlecan, suggesting its junctional/sulcular epithelial character.
Conclusion. The results showed that the paradental cyst was lined by epithelial cells with characteristics of the junctional/sulcular epithelium. The cyst can thus be considered as a kind of inclusion cyst arising in the periodontal pocket, most frequently of the mandibular third molars of young adults.


リンク情報
DOI
https://doi.org/10.1016/j.oooo.2015.04.001
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/26116019
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000360302600018&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/j.oooo.2015.04.001
  • ISSN : 2212-4403
  • eISSN : 1528-395X
  • PubMed ID : 26116019
  • Web of Science ID : WOS:000360302600018

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