論文

査読有り
2013年10月

Identification of the actinomycete 16S ribosomal RNA gene by polymerase chain reaction in oral inflammatory lesions

Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
  • Kayo Kuyama
  • ,
  • Kenji Fukui
  • ,
  • Eriko Ochiai
  • ,
  • Satoshi Maruyama
  • ,
  • Kimiharu Iwadate
  • ,
  • Takashi Saku
  • ,
  • Hirotsugu Yamamoto

116
4
開始ページ
485
終了ページ
491
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.oooo.2013.06.027

Objectives To examine the histopathological characteristics of inflammatory lesions containing Actinomyces based on DNA sequencing. Furthermore, case reports of actinomycosis in the maxillofacial region are summarized by a review of the literature. Study design The study comprised 12 cases of inflammatory lesions containing Actinomyces as diagnosed by DNA analysis. The average age of the subjects was 59 ± 15 years (6 males
6 females). Results The distribution of causative bacteria was: Actinomyces israelii in 9 cases, Actinomyces gerencseriae in 2 cases, and Actinomyces naeslundii in 1 case. Four cases diagnosed by DNA sequencing were positive for "Druse," a known morphological diagnostic characteristic of actinomycosis, and 8 cases lacked typical colony formation. Conclusions DNA analysis using paraffin-embedded samples is effective for both early and accurate diagnosis of oral lesions containing Actinomyces. © 2013 Elsevier Inc. All rights reserved.

リンク情報
DOI
https://doi.org/10.1016/j.oooo.2013.06.027
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/24035115
ID情報
  • DOI : 10.1016/j.oooo.2013.06.027
  • ISSN : 2212-4403
  • PubMed ID : 24035115
  • SCOPUS ID : 84883863552

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