論文

国際誌
2021年12月17日

Melanotic neuroectodermal tumor of infancy in the mandible: A case report.

Medicine
  • Ryoko Takeuchi
  • ,
  • Akinori Funayama
  • ,
  • Yohei Oda
  • ,
  • Tatsuya Abé
  • ,
  • Manabu Yamazaki
  • ,
  • Satoshi Maruyama
  • ,
  • Takafumi Hayashi
  • ,
  • Jun-Ichi Tanuma
  • ,
  • Tadaharu Kobayashi

100
50
開始ページ
e28001
終了ページ
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1097/MD.0000000000028001

RATIONALE: Melanocytic neuroectodermal tumor of infancy (MNTI) is a rare benign pigmented neoplasm that arises from the neural crest and has an aggressive growth pattern. It is predominantly seen in infants under 1 year of age, and the most common site of involvement is the maxilla. The currently accepted treatment is removal by surgical resection. Herein, we report a case of MNTI that involved the anterior alveolar ridge of the mandible in a 6-month-old infant. PATIENT CONCERNS: A case of a 6-month-old male child with a huge mass in the anterior alveolar ridge of the mandible. DIAGNOSIS: The tumor was diagnosed using histopathological and immunohistochemical techniques on the biopsy specimen obtained following incisional biopsy. Based on the findings, a final diagnosis of MNTI was established. INTERVENTIONS: Radical resection of the tumor was performed, after determining the extent of resection by referring to the mandibular 3D model created using the pre-operative CT data. OUTCOMES: The postoperative course was uneventful, and no recurrence has been observed to date for more than 4 years after surgery. LESSONS: This case emphasizes that early diagnosis and radical surgery are critical to the effective treatment, as MNTI exhibits rapid and destructive growth. It also requires careful and close follow-up because of high recurrence rates.

リンク情報
DOI
https://doi.org/10.1097/MD.0000000000028001
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/34918649
PubMed Central
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8678023
ID情報
  • DOI : 10.1097/MD.0000000000028001
  • PubMed ID : 34918649
  • PubMed Central 記事ID : PMC8678023

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