論文

査読有り
2003年9月

Bone augmentation osteogenesis using hydroacyapatite and beta-tricalcium phosphate blocks

JOURNAL OF ORAL AND MAXILLOFACIAL SURGERY
  • R Fujita
  • ,
  • A Yokoyama
  • ,
  • T Kawasaki
  • ,
  • T Kohgo

61
9
開始ページ
1045
終了ページ
1053
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/S0278-2391(03)00317-3
出版者・発行元
W B SAUNDERS CO

Purpose: In this study, we investigated the differences in osteogenesis and resorption between hydroxyapatite (HA) and beta-tricalcium phosphate (beta-TCP) implanted on the parietal bone of rats.
Materials and Methods: HA and beta-TCP were used in blocks with macropores and micropores. They were implanted between the parietal bone and the cranial periosteum in rats. Osteogenesis around the implanted materials was investigated histopathologically and histomorphometrically at 1, 2, 4, 8, and 24 weeks after surgery.
Results: At 2 weeks, osteogenesis from the parietal bone was observed around both materials, and new bone had attached directly to the surfaces of both materials. New bone grew into the pores of the upper regions of both materials with time. The beta-TCP block had a characteristic basophilic reticular structure in which the dissolution of the materials was observed close to the new bone. The HA blocks were stable for 24 weeks, whereas parts of the beta-TCP blocks were fractured and resorbed at 24 weeks. Histomorphometrically, the volume of new bone around HA was larger than that around beta-TCP. There was no remarkable change in the amount of remaining HA, but that of beta-TCP was decreased.
Conclusion: HA blocks in this model are suitable for onlay grafts because of its stability and osteogenesis,beta-TCP is not stable. Therefore, when beta-TCP blocks are used for onlay grafts, the mechanical stress on the recipient site should be taken into consideration because of resorption and fracture. (C) 2003 American Association of Oral and Maxillofacial Surgeons.

Web of Science ® 被引用回数 : 65

リンク情報
DOI
https://doi.org/10.1016/S0278-2391(03)00317-3
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/12966480
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000185046500011&DestApp=WOS_CPL
ID情報
  • DOI : 10.1016/S0278-2391(03)00317-3
  • ISSN : 0278-2391
  • PubMed ID : 12966480
  • Web of Science ID : WOS:000185046500011

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