論文

査読有り
2018年4月10日

Arteriovenous malformation in the sigmoid colon of a patient with Cowden disease treated with laparoscopy: A case report

BMC Surgery
  • Koichi Inukai
  • ,
  • Nobuhiro Takashima
  • ,
  • Shiro Fujihata
  • ,
  • Hirotaka Miyai
  • ,
  • Minoru Yamamoto
  • ,
  • Kenji Kobayashi
  • ,
  • Moritsugu Tanaka
  • ,
  • Tetsushi Hayakawa

18
1
開始ページ
21
終了ページ
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1186/s12893-018-0355-x
出版者・発行元
BioMed Central Ltd.

Background: Cowden disease is a genetic disorder associated with a mutation of the PTEN gene and is known to be easily complicated by generalized vascular malformations and malignant tumors. However, only a few reports have investigated the relationship between Cowden disease and vascular malformations. We present a case of Cowden disease along with a review of the literature. Case presentation: The patient was a 48-year-old man who visited our hospital complaining of fresh blood in his stools and shortness of breath. Hematological tests showed the patient had severe anemia. On physical examination, white papules - several millimeters in size - were observed between the patient's eyebrows. White papules were also observed on the left corner of his mouth and buccal mucosa. An upper gastrointestinal endoscopy showed densely-packed, white, flat protrusions in the esophagus. While lower gastrointestinal endoscopy revealed a mass accompanied by arterial pulsation in the sigmoid colon. A diagnosis of Cowden disease was confirmed and a laparoscopic sigmoidectomy was performed to address the arteriovenous malformations in the sigmoid colon. Post-surgery, the patient had an unremarkable recovery and was discharged 7 days later. Conclusions: We present a very rare case of Cowden disease with arteriovenous malformations occurring in the colon. Surgical resection is believed to be the first choice for treating congenital arteriovenous malformations of the intestines. However, the arteriovenous malformations in the colon in our patient were treated under laparoscopic guidance, making ours the first report describing laparoscopic treatment of colonic arteriovenous malformations occurring in the inferior mesenteric artery. Thus we demonstrate that laparoscopic treatment of arteriovenous malformations in the intestines is a minimally invasive and can be successfully applied in such cases.

リンク情報
DOI
https://doi.org/10.1186/s12893-018-0355-x
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/29636101
ID情報
  • DOI : 10.1186/s12893-018-0355-x
  • ISSN : 1471-2482
  • PubMed ID : 29636101
  • SCOPUS ID : 85045185670

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