論文

国際誌
2021年

SARC-F Predicts Mortality Risk of Older Adults during Hospitalization.

The journal of nutrition, health & aging
  • J Ueshima
  • ,
  • K Maeda
  • ,
  • Y Ishida
  • ,
  • A Shimizu
  • ,
  • T Inoue
  • ,
  • T Nonogaki
  • ,
  • R Matsuyama
  • ,
  • Y Yamanaka
  • ,
  • N Mori

25
7
開始ページ
914
終了ページ
920
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s12603-021-1647-x

OBJECTIVES: To determine the association between SARC-F scores and the in-hospital mortality risk among older patients admitted to acute care hospitals. DESIGN: Single-center retrospective study. SETTING: A university hospital. PARTICIPANTS: All consecutive patients aged older than 65 were admitted and discharged from the study hospital between July 2019 and September 2019. MEASUREMENTS: Relevant patient data included age, sex, body mass index, nutritional status, fat-free mass, disease, activities of daily living (ADL), duration of hospital stay, SARC-F, and occurrence of death within 30 days of hospitalization. The diseases that caused hospitalization and comorbidities (Charlson Comorbidity Index; CCI) were obtained from medical records. The Eastern Cooperative Oncology Group-performance status (PS) was used to determine ADL, and the in-hospital mortality rate within 30 days of hospitalization as the outcome. RESULTS: We analyzed 2,424 patients. The mean age was 75.9±6.9 and 55.5% were male. Fifty-three in-hospital mortalities occurred among the participants within the first 30 days of hospitalization. Patients who died in-hospital were older, had poorer nutritional status and severer PS scores, and more comorbidities than those who did not. A SARC-F score of ≥4 predicted a higher mortality risk within those 30 days with the following precision: sensitivity 0.792 and specificity 0.805. There were significantly more deaths in Kaplan-Meier curves regarding a score of SARC-F≥4 than a score of SARC-F<4 (p<0.001). Cox proportional hazard analysis was used to identify the clinical indicators most associated with in-hospital mortality. SARC-F≥4 (Hazard Ratio: HR 5.65, p<0.001), CCI scores (HR1.11, p=0.004), and infectious and parasitic diseases (HR3.13, p=0.031) were associated with in-hospital mortality. The SARC-F items with significant in-hospital mortality effects were assistance with walking (HR 2.55, p<0.001) and climbing stairs (HR 2.46, p=0.002). CONCLUSION: The SARC-F questionnaire is a useful prognostic indicator for older adults because a SARC-F ≥4 score during admission to an acute care hospital predicts in-hospital mortality within 30 days of hospitalization.

リンク情報
DOI
https://doi.org/10.1007/s12603-021-1647-x
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/34409971
ID情報
  • DOI : 10.1007/s12603-021-1647-x
  • PubMed ID : 34409971

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