三輪啓志 (Miwa Hiroshi) - マイポータル

基本情報

所属: 三重大学大学院医学系研究科特任准教授（研究担当）

学位: 医学博士(三重大学)

J-GLOBAL ID: 201801004495651553
researchmap会員ID: B000326089

研究分野

経歴

2018年4月 - 現在

三重大学, 大学院医学系研究科個別化がん免疫治療学, 特任准教授
2015年5月 - 2018年3月

三重大学医学部附属病院, 血液内科, 講師
2014年4月 - 2015年4月

遠山病院, 内科, 部長
1999年1月 - 2014年3月

愛知医科大学, 第二内科・血液内科, 助教授・准教授
1991年1月 - 1998年12月

三重大学医学部附属病院, 第二内科, 助手
1989年1月 - 1990年12月

MDアンダーソンがんセンター, 生化学・分子生物学, Project Investigator

学歴

1983年4月 - 1987年3月

三重大学, 大学院, 医学研究科
1977年4月 - 1983年3月

三重大学, 医学部, 医学科

論文

Establishment and characterization of a novel vincristine-resistant diffuse large B-cell lymphoma cell line containing the 8q24 homogeneously staining region.

Shohei Mizuno, Ichiro Hanamura, Akinobu Ota, Sivasundaram Karnan, Jo Kanasugi, Ayano Nakamura, Souichi Takasugi, Kaori Uchino, Tomohiro Horio, Mineaki Goto …

FEBS open bio 8(12) 1977-1991 2018年12月査読有り
Expression of CD25 fluctuates in the leukemia-initiating cell population of CD25-positive AML.

Kageyama Y, Miwa H, Arakawa R, Tawara I, Ohishi K, Masuya M, Nakase K, Katayama N

PLoS One 13(12) e0209295 2018年査読有り
CXCL12-CXCR4 Axis Is Required for Contact-Mediated Human B Lymphoid and Plasmacytoid Dendritic Cell Differentiation but Not T Lymphoid Generation

Hirohito Minami, Keiki Nagaharu, Yoshiki Nakamori, Kohshi Ohishi, Naoshi Shimojo, Yuki Kageyama, Takeshi Matsumoto, Yuka Sugimoto, Isao Tawara, Masahiro Masuya …

JOURNAL OF IMMUNOLOGY 199(7) 2343-2355 2017年10月査読有り
Overexpression of salivary-type amylase reduces the sensitivity to bortezomib in multiple myeloma cells.

Shohei Mizuno, Ichiro Hanamura, Akinobu Ota, Sivasundaram Karnan, Tomoko Narita, Masaki Ri, Motonori Mizutani, Mineaki Goto, Mayuko Gotou, Norikazu Tsunekawa …

Int J Hematol 102(5) 569-578 2015年査読有り
Comprehensive analysis of genetic alterations and their prognostic impacts in adult acute myeloid leukemia patients

R. Kihara, Y. Nagata, H. Kiyoi, T. Kato, E. Yamamoto, K. Suzuki, F. Chen, N. Asou, S. Ohtake, S. Miyawaki …

LEUKEMIA 28(8) 1586-1595 2014年8月査読有り
Importance of Glutamine Metabolism in Leukemia Cells by Energy Production Through TCA Cycle and by Redox Homeostasis

Mineaki Goto, Hiroshi Miwa, Masato Shikami, Norikazu Tsunekawa-Imai, Kazuto Suganuma, Shohei Mizuno, Miyuki Takahashi, Motonori Mizutani, Ichiro Hanamura, Masakazu Nitta

CANCER INVESTIGATION 32(6) 241-247 2014年7月査読有り
Adaptation of leukemia cells to hypoxic condition through switching the energy metabolism or avoiding the oxidative stress.

Mineaki Goto, Hiroshi Miwa, Kazuto Suganuma, Norikazu Tsunekawa-Imai, Masato Shikami, Motonori Mizutani, Shohei Mizuno, Ichiro Hanamura, Masakazu Nitta

BMC Cancer 14 76 2014年査読有り
Growth of xenotransplanted leukemia cells is influenced by diet nutrients and is attenuated with 2-deoxyglucose

Norikazu Tsunekawa-Imai, Hiroshi Miwa, Masato Shikami, Kazuto Suganuma, Mineaki Goto, Shohei Mizuno, Miyuki Takahashi, Motonori Mizutani, Tomohiro Horio, Hiroko Komatsubara …

LEUKEMIA RESEARCH 37(9) 1132-1136 2013年9月査読有り
Leukemia cells demonstrate a different metabolic perturbation provoked by 2-deoxyglucose

Hiroshi Miwa, Masato Shikami, Mineaki Goto, Shohei Mizuno, Miyuki Takahashi, Norikazu Tsunekawa-Imai, Takamasa Ishikawa, Motonori Mizutani, Tomohiro Horio, Mayuko Gotou …

ONCOLOGY REPORTS 29(5) 2053-2057 2013年5月査読有り
Establishment of a Novel Human Myeloid Leukemia Cell Line, AMU-AML1, Carrying t(12;22)(p13;q11) without Chimeric MN1-TEL and with High Expression of MN1

Mayuko Gotou, Ichiro Hanamura, Hisao Nagoshi, Motohiro Wakabayashi, Natsumi Sakamoto, Norikazu Tsunekawa, Tomohiro Horio, Mineaki Goto, Shohei Mizuno, Miyuki Takahashi …

GENES CHROMOSOMES & CANCER 51(1) 42-53 2012年1月査読有り
Energy metabolism of leukemia cells: glycolysis versus oxidative phosphorylation

Kazuto Suganuma, Hiroshi Miwa, Norikazu Imai, Masato Shikami, Mayuko Gotou, Mineaki Goto, Shohei Mizuno, Miyuki Takahashi, Hidesuke Yamamoto, Akihito Hiramatsu …

LEUKEMIA & LYMPHOMA 51(11) 2112-2119 2010年11月査読有り
Central nervous system involvement in intravascular large B-cell lymphoma: A retrospective analysis of 109 patients

Kazuyuki Shimada, Takuhei Murase, Kosei Matsue, Masataka Okamoto, Naoaki Ichikawa, Norifumi Tsukamoto, Nozomi Niitsu, Hiroshi Miwa, Hideki Asaoku, Hiroshi Kosugi …

CANCER SCIENCE 101(6) 1480-1486 2010年6月査読有り
Growth inhibition of AML cells with specific chromosome abnormalities by monoclonal antibodies to receptors for vascular endothelial growth factor

Norikazu Imai, Hiroshi Miwa, Masato Shikami, Kazuto Suganuma, Mayuko Gotoh, Akihito Hiramatsu, Motohiro Wakabayashi, Masaya Watarai, Ichiro Hanamura, Akira Imamura …

LEUKEMIA RESEARCH 33(12) 1650-1657 2009年12月査読有り
Retrospective analysis of intravascular large B-cell lymphoma treated with rituximab-containing chemotherapy as reported by the IVL study group in Japan

Kazuyuki Shimada, Kosei Matsue, Kazuhito Yamamoto, Takuhei Murase, Naoaki Ichikawa, Masataka Okamoto, Nozomi Niitsu, Hiroshi Kosugi, Norifumi Tsukamoto, Hiroshi Miwa …

JOURNAL OF CLINICAL ONCOLOGY 26(19) 3189-3195 2008年7月査読有り
Clinical and prognostic significance of cytokine receptor expression in adult acute lymphoblastic leukemia: interleukin-2 receptor α-chain predicts a poor prognosis.

K Nakase, K Kita, H Miwa, K Nishii, M Shikami, I Tanaka, H Tsutani, T Ueda, K Nasu, T Kyo …

Leukemia 21(2) 326-332 2007年2月査読有り
t(8;21) acute myeloid leukaemia cells are dependent on vascular endothelial growth factor (VEGF)/VEGF receptor type2 pathway and phosphorylation of Akt

Norikazu Imai, Masato Shikami, Hiroshi Miwa, Kazuto Suganuma, Akihito Hiramatsu, Masaya Watarai, Atsushi Satoh, Masato Itoh, Akira Imamura, Hidetsugu Mihara …

BRITISH JOURNAL OF HAEMATOLOGY 135(5) 673-682 2006年12月査読有り
Gene expression changes in a patient presenting nonleukaemic nasal granulocytic sarcoma to acute myelogenous leukaemia using 40 K cDNA microarray

H. Teramoto, H. Miwa, V. Patel, N. Letwin, M. D. Castellone, N. Imai, M. Shikami, A. Imamura, J. S. Gutkind, M. Nitta …

CLINICAL AND LABORATORY HAEMATOLOGY 28(4) 262-266 2006年8月査読有り
Low p53 expression of acute myelocytic leukemia cells with t(8;21) chromosome abnormality: Association with low p14(ARF) expression

M Shikami, H Miwa, K Nishii, T Kyo, Tanaka, I, H Shiku, K Kita, M Nitta

LEUKEMIA RESEARCH 30(4) 379-383 2006年4月査読有り
Disease-specific expression of VEGF and its receptors in AML cells: possible autocrine pathway of VEGF/type1 receptor of VEGF in t(15;17) AML and VEGF/type2 receptor of VEGF in t(8;21) AML

A Hiramatsu, H Miwa, M Shikami, T Ikai, E Tajima, H Yamamoto, N Imai, A Hattori, T Kyo, M Watarai …

LEUKEMIA & LYMPHOMA 47(1) 89-95 2006年1月査読有り
Placenta growth factor stimulates the growth of Philadelphia chromosome positive acute lymphoblastic leukemia cells by both autocrine and paracrine pathways

T Ikai, H Miwa, M Shikami, A Hiramatsu, E Tajima, H Yamamoto, N Imai, A Hattori, K Nishii, K Miura …

EUROPEAN JOURNAL OF HAEMATOLOGY 75(4) 273-279 2005年10月査読有り

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三輪啓志

基本情報

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経歴

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