岡田真理子 (Mariko Okada) - マイポータル

基本情報

The Mediator subunit MED12 promotes formation of HSF1 condensates on heat shock response element arrays in heat-shocked cells.

Mariko Okada, Mitsuaki Fujimoto, Pratibha Srivastava, Akanksha Pandey, Ryosuke Takii, Akira Nakai

FEBS letters 597(13) 1702-1717 2023年7月
HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

Mitsuaki Fujimoto, Ryosuke Takii, Masaki Matsumoto, Mariko Okada, Keiich I Nakayama, Ryuichiro Nakato, Katsunori Fujiki, Katsuhiko Shirahige, Akira Nakai

Nature communications 13(1) 4355-4355 2022年7月29日
MED12 interacts with the heat-shock transcription factor HSF1 and recruits CDK8 to promote the heat-shock response in mammalian cells.

Pratibha Srivastava, Ryosuke Takii, Mariko Okada, Mitsuaki Fujimoto, Akira Nakai

FEBS letters 595(14) 1933-1948 2021年7月
HSF1 is required for induction of mitochondrial chaperones during the mitochondrial unfolded protein response.

Arpit Katiyar, Mitsuaki Fujimoto, Ke Tan, Ai Kurashima, Pratibha Srivastava, Mariko Okada, Ryosuke Takii, Akira Nakai

FEBS open bio 10(6) 1135-1148 2020年6月