Yuya Haga

Silver nanoparticles suppress forskolin-induced syncytialization in BeWo cells

Yuji Sakahashi, Kazuma Higashisaka, Ryo Isaka, Rina Izutani, Jiwon Seo, Atsushi Furuta, Akemi Yamaki-Ushijima, Hirofumi Tsujino, Yuya Haga, Akitoshi Nakashima, Yasuo Tsutsumi

Nanotoxicology, 1-12, Jan 3, 2023

Silver Nanoparticles Suppress Retinoic Acid-Induced Neuronal Differentiation in Human-Derived Neuroblastoma SH-SY5Y Cells

Shintaro Yamaguchi, Ryo Isaka, Yuji Sakahashi, Hirofumi Tsujino, Yuya Haga, Kazuma Higashisaka, Yasuo Tsutsumi

ACS Applied Nano Materials, 5(12) 19025-19034, Dec 23, 2022

Osimertinib-tolerant lung cancer cells are susceptible to ferroptosis.

Hiroto Konishi, Yuya Haga, Ying Lin, Hirofumi Tsujino, Kazuma Higashisaka, Yasuo Tsutsumi

Biochemical and biophysical research communications, 641 116-122, Dec 10, 2022

Alpha-crystallin B chains enhance cell migration in basal-like 2 triple-negative breast cancer cells

L. Yang, K. Higashisaka, Y. Haga, H. Tsujino, K. Nagano, Y. Tsutsumi

PHARMAZIE, 77(2), Feb, 2022

Subvisible Particles Derived by Dropping Stress Enhance Anti-PEG Antibody Production and Clearance of PEGylated Proteins in Mice.

Takaki Nakajima, Kazuya Nagano, Yuka Fukuda, Yu Ishima, Hiroko Shibata, Ryo Isaka, Tian-Qi Zhang, Yuya Haga, Kazuma Higashisaka, Hirofumi Tsujino, Tatsuhiro Ishida, Akiko Ishii-Watabe, Yasuo Tsutsumi

Journal of pharmaceutical sciences, 111(5) 1363-1369, Jan 31, 2022 Peer-reviewed

Alpha-crystallin B chains in trastuzumab-resistant breast cancer cells promote endothelial cell tube formation through activating mTOR.

Lili Yang, Kazuma Higashisaka, Masafumi Shimoda, Yuya Haga, Naoki Sekine, Hirofumi Tsujino, Kazuya Nagano, Kenzo Shimazu, Yasuo Tsutsumi

Biochemical and biophysical research communications, 588 175-181, Jan 15, 2022 Peer-reviewed

Amorphas Silica Nanoparticles Decrease Human Chorionic Gonadotropin β Expression During Syncytialization of BeWo Cell

Yuji Sakahashi, Rena Yamamoto, Go Kitahara, Rina Izutani, Hirofumi Tsujino, Yuya Haga, Kazuma Higashisaka, Yasuo Tsutsumi

BPB Reports, 5(6) 154-158, 2022

Indoxyl Sulfate Induces an Inflammatory Response in the Proximal Tubule via Macrophages

Isaka R, Ishida N, Kitahara G, Sakahashi Y, Haga Y, Tsujino H, Nagano K, Higashisaka K, Tsutsumi Y

BPB Reports, 4(6) 198-201, Nov, 2021 Peer-reviewed

TSHZ2 is an EGF-regulated tumor suppressor that binds to the cytokinesis regulator PRC1 and inhibits metastasis

Mary L. Uribe, Maik Dahlhoff, Rajbir N. Batra, Nishanth B. Nataraj, Yuya Haga, Diana Drago-Garcia, Ilaria Marrocco, Arunachalam Sekar, Soma Ghosh, Itay Vaknin, Sacha Lebon, Lior Kramarski, Yasuo Tsutsumi, Inpyo Choi, Oscar M. Rueda, Carlos Caldas, Yosef Yarden

Science Signaling, 14(688) eabe6156-eabe6156, Jun 22, 2021 Peer-reviewed

Host-dependent Phenotypic Resistance to EGFR Tyrosine Kinase Inhibitors

Yuya Haga, Ilaria Marrocco, Ashish Noronha, Mary Luz Uribe, Nishanth Belugali Nataraj, Arunachalam Sekar, Diana Drago-Garcia, Simone Borgoni, Moshit Lindzen, Suvendu Giri, Stefan Wiemann, Yasuo Tsutsumi, Yosef Yarden

Cancer Research, 81(14) 3555.2020-3875, May 3, 2021 Peer-reviewedLead author

Inhibition of Akt/mTOR pathway overcomes intrinsic resistance to dasatinib in triple-negative breast cancer.

Yuya Haga, Kazuma Higashisaka, Lili Yang, Naoki Sekine, Ying Lin, Hirofumi Tsujino, Kazuya Nagano, Yasuo Tsutsumi

Biochemical and biophysical research communications, 533(4) 672-678, Dec 17, 2020 Peer-reviewed

Progesterone receptor membrane component 1 leads to erlotinib resistance, initiating crosstalk of Wnt/β-catenin and NF-κB pathways, in lung adenocarcinoma cells.

Ying Lin, Kazuma Higashisaka, Takuya Shintani, Ayaka Maki, Sachiyo Hanamuro, Yuya Haga, Shinichiro Maeda, Hirofumi Tsujino, Kazuya Nagano, Yasushi Fujio, Yasuo Tsutsumi

Scientific reports, 10(1) 4748-4748, Mar 16, 2020 Peer-reviewed

ETS Proteins Bind with Glucocorticoid Receptors: Relevance for Treatment of Ewing Sarcoma.

Swati Srivastava, Nishanth Belugali Nataraj, Arunachalam Sekar, Soma Ghosh, Chamutal Bornstein, Diana Drago-Garcia, Lee Roth, Donatella Romaniello, Ilaria Marrocco, Eyal David, Yuval Gilad, Mattia Lauriola, Ron Rotkopf, Adi Kimchi, Yuya Haga, Yasuo Tsutsumi, Olivier Mirabeau, Didier Surdez, Andrei Zinovyev, Olivier Delattre, Heinrich Kovar, Ido Amit, Yosef Yarden

Cell reports, 29(1) 104-117, Oct 1, 2019 Peer-reviewed

エルロチニブ耐性化機構におけるPGRMC1の機能解析

林穎, 東阪和馬, 新谷拓也, 花室紗知代, 泉沢航平, 芳賀優弥, 前田真一郎, 辻野博文, 長野一也, 藤尾慈, 堤康央

日本薬学会年会要旨集, 139年会(4) 51-51, Mar, 2019

Dasatinib shows different cytotoxicity in triple-negative breast cancer cell lines.

Haga Yuya, Higashisaka Kazuma, Yang Lili, Sekine Naoki, Nagano Kazuya, Tsutsumi Yasuo

MOLECULAR CANCER RESEARCH, 16(8) 27-28, Aug, 2018 Peer-reviewed

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