2015年1月1日
Assessing tumor angiogenesis in histological samples
Handbook of Vascular Biology Techniques
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- 開始ページ
- 231
- 終了ページ
- 243
- 記述言語
- 英語
- 掲載種別
- 論文集(書籍)内論文
- DOI
- 10.1007/978-94-017-9716-0_20
- 出版者・発行元
- Springer Netherlands
Angiogenesis is a hallmark of cancer [1] and occurs in most human tumors. It has been shown that angiogenic tumors are more likely to develop metastasis and exhibit resistance to standard cancer therapies [2], making tumor angiogenesis a prognostic and sometimes predictive biomarker [3, 4]. Although new imaging technologies, such as dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) or positron emission tomography-computed tomography (PET-CT) scans, are clinically available to visualize tumor angiogenesis in vivo [5, 6], histological assessment of tumor angiogenesis remains a technique of interest, as it can provide information on the capillary level of newly developed microvessels in different parts of the tumor [7]. Via histological examination, the relationship between tumor microvessels and other clinicopathological tumor characteristics can be evaluated as well [8].
- ID情報
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- DOI : 10.1007/978-94-017-9716-0_20
- SCOPUS ID : 84943178439