Papers

Peer-reviewed International journal
Sep 6, 2020

Continuous glucose monitoring in patients with remission of type 2 diabetes after laparoscopic sleeve gastrectomy without or with duodenojejunal bypass.

Clinical obesity
  • Shojiro Sawada
  • Shinjiro Kodama
  • Satoko Tsuchiya
  • Satoko Kurosawa
  • Akira Endo
  • Hiroto Sugawara
  • Shinichiro Hosaka
  • Yohei Kawana
  • Yoichiro Asai
  • Junpei Yamamoto
  • Yuichiro Munakata
  • Tomohito Izumi
  • Kei Takahashi
  • Keizo Kaneko
  • Junta Imai
  • Hirofumi Imoto
  • Naoki Tanaka
  • Takeshi Naitoh
  • Yasushi Ishigaki
  • Hideki Katagiri
  • Display all

Volume
10
Number
6
First page
e12409
Last page
Language
English
Publishing type
Research paper (scientific journal)
DOI
10.1111/cob.12409

Bariatric surgery is associated with a high remission rate of type 2 diabetes mellitus. However, it is unclear whether patients showing remission of diabetes actually have normal blood glucose levels throughout the day. We therefore performed continuous glucose monitoring (CGM) in 15 ambulatory patients showing remission of diabetes after laparoscopic sleeve gastrectomy (LSG) without or with duodenojejunal bypass (DJB) at the time of diabetic remission (12.9 ± 1.8 months after bariatric surgery). The definition of remission of diabetes was based on the American Diabetes Association criteria. The mean, SD, and coefficient of variation (CV) of glucose calculated from CGM were 6.2 ± 0.6 mmol/L, 1.5 ± 0.4 mmol/L, and 23.7 ± 6.2%, respectively. These values were higher than those of healthy participants without diabetes previously reported. The percentages of time spent above 10.0 mmol/L and below 3.9 mmol/L were 2.6 (IQR 0-5.0)% and 0 (IQR 0-8.0)%, respectively. Thus, patients with remission of diabetes after LSG or LSG/DJB still had substantial periods of hyperglycemia and hypoglycemia throughout the day. Therefore, we must manage patients with diabetes carefully, even after apparent remission of type 2 diabetes in response to bariatric surgery.

Link information
DOI
https://doi.org/10.1111/cob.12409
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32892484
ID information
  • DOI : 10.1111/cob.12409
  • Pubmed ID : 32892484

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