Masahiko Tanaka

Profile Information

Affiliation: Associate Professor, Graduate School of Pharmaceutical Sciences Department of Cellular Biophysics, Nagoya City University

Degree: 博士（薬学）(東京大学)

Researcher number: 60267953
ORCID ID: https://orcid.org/0000-0002-1344-0895
J-GLOBAL ID: 200901049624843611
researchmap Member ID: 1000170833

External link: http://www.nagoya-cu.ac.jp/phar/grad/soyaku/seimei/chobunshi/

Research Interests

Research Areas

Research History

2007 - Present

Associate Professor, Department of Cellular Biophysics, Graduate School of Pharmaceutical Sciences, Nagoya City University
1998 - 2006

Lecturer, Division of Cell Biology, Institute for Comprehensive Medical Science, Fujita Health University
2006

Associate Professor, Graduate School of Pharmaceutical Sciences, Nagoya City University
1994 - 1998

Assistant Professor, Division of Cell Biology, Institute for Comprehensive Medical Science, Fujita Health University

Education

Committee Memberships

Oct, 2003 - Present

Councilor, The Japanese Society for Neurochemistry

Awards

Oct, 2001

Aword for Young Investigator of Japanese Society for Neurochemistry

Papers

Methiothepin downregulates SNAP‐23 and inhibits degranulation of rat basophilic leukemia cells and mouse bone marrow‐derived mast cells

Daisuke Kondo, Ruriko Suzuki, Ayako Matsumura, Hitomi Meguri, Masahiko Tanaka, Makoto Itakura, Naohide Hirashima

European Journal of Immunology, Sep 22, 2023 Peer-reviewed
Calcineurin B1 deficiency reduces proliferation, increases apoptosis, and alters secretion in enteric glial cells of mouse small intestine in culture

Hikaru Teramoto, Naohide Hirashima, Masahiko Tanaka

Cells, 12(14) 1867, Jul 17, 2023 Peer-reviewedLast authorCorresponding author
A simple method for purified primary culture of enteric glial cells from mouse small intestine

Hikaru Teramoto, Naohide Hirashima, Masahiko Tanaka

Biological and Pharmaceutical Bulletin, 45(4) 547-551, Apr 1, 2022
Promotion of dendritic differentiation of cerebellar Purkinje cells by Ca2+/calmodulin-dependent protein kinase IIα, IIβ and IV and possible involvement of CREB phosphorylation.

Yuki Horie, Toshiaki Arame, Naohide Hirashima, Masahiko Tanaka

Neuroscience, 458 87-98, Mar, 2021 Peer-reviewedLast authorCorresponding author
Calcineurin B1 deficiency in glial cells reduces gastrointestinal motility and results in maldigestion and/or malabsorption in mice

Umi Okura, Naohide Hirashima, Masahiko Tanaka

Biological and Pharmaceutical Bulletin, 42(7) 1230-1235, Jul, 2019 Peer-reviewedLast authorCorresponding author
Development of 3D imaging technique of reconstructed human epidermis with immortalized human epidermal cell line

Yu Inoue, Seiji Hasegawa, Katsuma Miyachi, Takaaki Yamada, Satoru Nakata, Sari Ipponjima, Terumasa Hibi, Tomomi Nemoto, Masahiko Tanaka, Ryo Suzuki …

Experimental Dermatology, 27(5) 563-570, May, 2018 Peer-reviewed
Calcineurin B1 deficiency in glial cells induces mucosal degeneration and inflammation in mouse small intestine

Maya Fujita, Takaki Yagi, Umi Okura, Jun'ichi Tanaka, Naohide Hirashima, Masahiko Tanaka

Biological and Pharmaceutical Bulletin, 41(5) 786-796, May, 2018 Peer-reviewedLast authorCorresponding author
Expression of the GluA2 subunit of glutamate receptors is required for the normal dendritic differentiation of cerebellar Purkinje cells

Masahiko Tanaka, Tomomi Senda, Naohide Hirashima

Neuroscience Letters, 657 22-26, Sep, 2017 Peer-reviewedLead authorCorresponding author
The dendritic differentiation of Purkinje neurons: unsolved mystery in formation of unique dendrites

Masahiko Tanaka

Cerebellum, 14(3) 227-230, Jun, 2015 Peer-reviewedLead authorLast authorCorresponding author
Optimization of single-cell electroporation protocol for forced gene expression in primary neuronal cultures

Shin Nishikawa, Naohide Hirashima, Masahiko Tanaka

Molecular Biotechnology, 56(9) 824-832, Sep, 2014 Peer-reviewedLast authorCorresponding author
Orai-2 is localized on secretory granules and regulates antigen-evoked Ca2+ mobilization and exocytosis in mast cells

Miho Ikeya, Kiyoshi Yamanoue, Yuji Mochizuki, Hirofumi Konishi, Satoshi Tadokoro, Masahiko Tanaka, Ryo Suzuki, Naohide Hirashima

Biochemical and Biophysical Research Communications, 451(1) 62-67, Aug, 2014 Peer-reviewed
ZIP2 protein, a zinc transporter, is associated with keratinocyte differentiation

Yu Inoue, Seiji Hasegawa, Sadanori Ban, Takaaki Yamada, Yasushi Date, Hiroshi Mizutani, Satoru Nakata, Masahiko Tanaka, Naohide Hirashima

Journal of Biological Chemistry, 289(31) 21451-21462, Aug, 2014 Peer-reviewed
Dendritic differentiation of cerebellar Purkinje cells is promoted by ryanodine receptors expressed by Purkinje and granule cells

Ryo Ohashi, Shin-ichi Sakata, Asami Naito, Naohide Hirashima, Masahiko Tanaka

Developmental Neurobiology, 74(4) 467-480, Apr, 2014 Peer-reviewedLast authorCorresponding author
Detection of asymmetric distribution of phospholipids by fluorescence resonance energy transfer

Yoko Nishimura, Satoshi Tadokoro, Masahiko Tanaka, Naohide Hirashima

Biochemical and Biophysical Research Communications, 420(4) 926-930, Apr, 2012 Peer-reviewed
Long-term gene-silencing effects of siRNA introduced by single-cell electroporation into postmitotic CNS neurons

Masahiko Tanaka, Minami Asaoka, Yuchio Yanagawa, Naohide Hirashima

Neurochemical Research, 36(8) 1482-1489, Aug, 2011 Peer-reviewedLead authorCorresponding author
A role for myosin Va in cerebellar plasticity and motor learning: a possible mechanism underlying neurological disorder in myosin Va disease

Mariko Miyata, Yasushi Kishimoto, Masahiko Tanaka, Kouichi Hashimoto, Naohide Hirashima, Yoshiharu Murata, Masanobu Kano, Yoshiko Takagishi

Journal of Neuroscience, 31(16) 6067-6078, Apr, 2011 Peer-reviewed
培養神経細胞におけるGFPイメージングを用いた単一細胞レベルでのRNA干渉効果の解析

田中正彦

バイオイメージング, 19 9-13, Jun, 2010 Lead authorLast authorCorresponding author
Dendrite formation of cerebellar Purkinje cells

Masahiko Tanaka

Neurochemical Research, 34(12) 2078-2088, Dec, 2009 Peer-reviewedLead authorLast authorCorresponding author
Effects of 1-naphthyl acetyl spermine on dendrite formation by cultured cerebellar Purkinje cells

Masahiko Tanaka, Shin-ichi Sakata, Naohide Hirashima

Neuroscience Letters, 462(1) 30-32, Sep, 2009 Peer-reviewedLead authorCorresponding author
Transfer of small interfering RNA by single-cell electroporation in cerebellar cell cultures

Masahiko Tanaka, Yuchio Yanagawa, Naohide Hirashima

Journal of Neuroscience Methods, 178(1) 80-86, Mar, 2009 Peer-reviewedLead authorCorresponding author

Misc.

マスト細胞の分泌におけるOrai-2の2つの役割

服部幸希, 望月雄司, 二宮里帆, 田中正彦, 鈴木亮, 平嶋尚英

生体膜と薬物の相互作用シンポジウム講演要旨集, 41st, 2019
マスト細胞の分泌顆粒に局在するCaチャネルOrai-2による細胞内Ca²⁺濃度制御

服部幸希, 鈴木亮, 鈴木亮, 望月雄司, 田中正彦, 平嶋尚英

日本薬学会年会要旨集(CD-ROM), 138th, 2018
The role of ryanodine receptors in dendrite formation of cerebellar Purkinje cells

Ryo Ohashi, Shin-ichi Sakata, Naohide Hirashima, Masahiko Tanaka

NEUROSCIENCE RESEARCH, 71 E234-E234, 2011
Effects of myosin Va knockdown by single-cell electroporation of siRNA in cerebellar Purkinje cells

Masahiko Tanaka, Yoshiko Takagishi, Naohide Hirashima

NEUROSCIENCE RESEARCH, 71 E117-E117, 2011
Single-cell electroporation technique applied to cultured cerebellar neurons

Masahiko Tanaka, Yuchio Yanagawa, Naohide Hirashima

NEUROSCIENCE RESEARCH, 68 E221-E221, 2010
Roles of calcium channels in dendrite formation of cerebellar Purkinje cells

Masahiko Tanaka, Shin-ichi Sakata, Naohide Hirashima

NEUROSCIENCE RESEARCH, 65 S200-S200, 2009
Regulation of dendrite development of cerebellar Purkinje cells by a diffusive factor

Masahiko Tanaka, Tohru Marunouchi

NEUROSCIENCE RESEARCH, 55 S85-S85, 2006
Expression and function of Notch2 in glial cells in mouse brain

TANAKA Masahiko, KADOKAWA Yuzo, HAMADA Yoshio, MARUNOUCHI Tohru

21 597-597, Dec 1, 1998

Books and Other Publications

Single-cell electroporation of siRNA in primary neuronal cultures

Springer, New York, 2012
Role of a chondroitin sulfate proteoglycan PTPz in dendrite development of cerebellar Purkinje cells

Research Signpost, Kerala, India, 2007

Professional Memberships

Research Projects

Roles of calcineurin and cell interactions in enteric glial cells and hepatic stellate cells

Kakenhi, JSPS, 2019 - 2021

TANAKA Masahiko
Roles of enteric glial cells and calcineurin in the function and homeostasis of the small intestine

Kakenhi, JSPS, 2016 - 2018

TANAKA Masahiko
Investigation of mechanisms of dendritic differentiation of cerebellar Purkinje cells mediated by ryanodine receptors

Kakehnhi, 基盤研究(C), JSPS, 2013 - 2015

TANAKA Masahiko
Analysis of molecular mechanisms of formation of complex and organized dendrites by cerebellar Purkinje cells

Kakenhi, 基盤研究(C), JSPS, 2010 - 2012

TANAKA Masahiko
神経幹細胞の最終細胞分裂に及ぼす細胞内外因子の効果

Kakenhi, 基盤研究(B), JSPS, 2003 - 2004

MARUNOUCHI Tohru
PTPz及びバーグマン・グリア細胞によるプルキンエ細胞樹状突起の形態形成制御機構

JSPS, 若手研究(B), JSPS, 2003 - 2004

TANAKA Masahiko
切片培養系を用いた小脳形成における生細胞動的観察系の開発と応用

Kakenhi, 奨励研究(A), JSPS, 1999 - 2000

TANAKA Masahiko
Analyses of Notch2 function in vertebrate neural development

Kakenhi, 基盤研究(C), JSPS, 1998 - 1999

KADOKAWA Yuzo
Involvement and activation of ICE family proteases in apoptosis of cerebellar granule neurons

Kakaenhi, 奨励研究(A), JSPS, 1997 - 1998

TANAKA Masahiko
Developmental stage-specific mechanisms of neuronal cell death in rat cerebellum

Kakenhi, JSPS, 1996 - 1996

TANAKA Masahiko

Profile Information

Research Interests

Research Areas

Research History

Education

Committee Memberships

Awards

Papers

Misc.

Books and Other Publications

Professional Memberships

Research Projects

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