Taniguchi Satoshi

Profile Information

Affiliation: Graduate School of Medicine, The University of Tokyo

Researcher number: 60734465
ORCID iD: https://orcid.org/0000-0002-2066-1979
J-GLOBAL ID: 201801009450933363
researchmap Member ID: B000337699

Research Interests

Research Areas

Life sciences / Virology /

Research History

Jan, 2024 - Present

Graduate School of Medicine, The University of Tokyo
Apr, 2018 - Dec, 2023

Senior research officer, Department of Virology I, National Institute of Infectious Diseases
Jan, 2021 - Jan, 2023

International Visiting Scientist, Department of Pathology, University of Texas, Medical Branch
Jan, 2016 - Dec, 2017

Researcher, Laboratory of arboviruses, Department of Virology I, National Institute of Infectious Diseases
Apr, 2014 - Dec, 2015

Researcher, Special Pathogens Laboratory, Department of Virology I, National Institute of Infectious Diseases

Education

Apr, 2010 - Mar, 2014

Veterinary Medical Sciences, Graduate School of Agricultural and Life Sciences, The University of Tokyo
Apr, 2006 - Mar, 2010

The University of Tokyo

Committee Memberships

Jun, 2020 - Present

Committee on Laboratory Animal Infectious Disease Control, Japanese Association for Laboratory Animal Science

Papers

N-glycosylation of viral glycoprotein is a novel determinant for the tropism and virulence of highly pathogenic tick-borne bunyaviruses.

Masayuki Shimojima, Satoko Sugimoto, Satoshi Taniguchi, Takahiro Maeki, Tomoki Yoshikawa, Takeshi Kurosu, Shigeru Tajima, Chang-Kweng Lim, Hideki Ebihara

PLoS pathogens, 20(7) e1012348, Jul, 2024
Development of reverse genetics system for Guanarito virus: substitution of E1497K in the L protein of Guanarito virus S-26764 strain changes plaque phenotype and growth kinetics.

Satoshi Taniguchi, Junki Maruyama, Takeshi Saito, Kirsten Littlefield, Rachel A Reyna, John T Manning, Cheng Huang, Masayuki Saijo, Slobodan Paessler

Journal of virology, 98(2) e0196423, Feb 20, 2024
Pathological and virological findings of type I interferon receptor knockout mice upon experimental infection with Heartland virus.

Hikaru Fujii, Shuetsu Fukushi, Tomoki Yoshikawa, Noriyo Nagata, Satoshi Taniguchi, Masayuki Shimojima, Souichi Yamada, Hideki Tani, Akihiko Uda, Takahiro Maeki …

Virus research, 340 199301-199301, Dec 16, 2023
Inhibitors of cannabinoid receptor 1 suppress the cellular entry of Lujo virus.

Miyuki Kimura, Risa Matsuoka, Satoshi Taniguchi, Junki Maruyama, Slobodan Paessler, Saori Oka, Atsushi Yamashita, Takasuke Fukuhara, Yoshiharu Matsuura, Hideki Tani

Virology, 587 109867-109867, Aug 10, 2023
Vaccine Candidates against Arenavirus Infections

Takeshi SAITO, Rachel Reyna, Satoshi Taniguchi, Kirsten E Littlefield, Slobodan Paessler, Junki Maruyama

Vaccines, Mar, 2023
Analysis of cross-reactivity among flaviviruses using sera of patients with dengue showed the importance of neutralization tests with paired serum samples for the correct interpretations of serological test results for dengue.

Takahiro Maeki, Shigeru Tajima, Naokatsu Ando, Yuji Wakimoto, Kayoko Hayakawa, Satoshi Kutsuna, Fumihiro Kato, Satoshi Taniguchi, Eri Nakayama, Chang-Kweng Lim …

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, Jan 24, 2023
Isolation and characterization of an orthoreovirus from Indonesian fruit bats.

Kittiya Intaruck, Yukari Itakura, Mai Kishimoto, Herman M Chambaro, Agus Setiyono, Ekowati Handharyani, Kentaro Uemura, Hayato Harima, Satoshi Taniguchi, Masayuki Saijo …

Virology, 575 10-19, Aug 15, 2022
Susceptibility of Type I Interferon Receptor Knock-Out Mice to Heartland Bandavirus (HRTV) Infection and Efficacy of Favipiravir and Ribavirin in the Treatment of the Mice Infected with HRTV.

Hikaru Fujii, Hideki Tani, Kazutaka Egawa, Satoshi Taniguchi, Tomoki Yoshikawa, Shuetsu Fukushi, Souichi Yamada, Shizuko Harada, Takeshi Kurosu, Masayuki Shimojima …

Viruses, 14(8), Jul 28, 2022
Reverse Genetics System for Heartland Bandavirus: NSs Protein Contributes to Heartland Bandavirus Virulence.

Satoshi Taniguchi, Takuya Inagaki, Shigeru Tajima, Tadaki Suzuki, Tomoki Yoshikawa, Shuetsu Fukushi, Eun-Sil Park, Hikaru Fujii, Shigeru Morikawa, Hideki Tani …

Journal of virology, 96(7) e0004922, Apr 13, 2022
Genotype-Dependent Immunogenicity of Dengue Virus Type 2 Asian I and Asian/American Genotypes in Common Marmoset (Callithrix jacchus): Discrepancy in Neutralizing and Infection-Enhancing Antibody Levels between Genotypes.

Nor Azila Muhammad Azami, Meng Ling Moi, Yasushi Ami, Yuriko Suzaki, Satoshi Taniguchi, Shigeru Tajima, Masayuki Saijo, Tomohiko Takasaki, Ichiro Kurane, Chang-Kweng Lim

Microorganisms, 9(11), Oct 21, 2021
Leu-to-Phe substitution at prM146 decreases the growth ability of Zika virus and partially reduces its pathogenicity in mice.

Takuya Inagaki, Satoshi Taniguchi, Yasuhiro Kawai, Takahiro Maeki, Eri Nakayama, Shigeru Tajima, Haruko Takeyama, Chang Kweng Lim, Masayuki Saijo

Scientific reports, 11(1) 19635-19635, Oct 4, 2021
Immunogenicity and Protective Ability of Genotype I-Based Recombinant Japanese Encephalitis Virus (JEV) with Attenuation Mutations in E Protein against Genotype V JEV.

Shigeru Tajima, Satoshi Taniguchi, Eri Nakayama, Takahiro Maeki, Takuya Inagaki, Masayuki Saijo, Chang Kweng Lim

Vaccines, 9(10), Sep 25, 2021
Embryonic Stage of Congenital Zika Virus Infection Determines Fetal and Postnatal Outcomes in Mice.

Eri Nakayama, Yasuhiro Kawai, Satoshi Taniguchi, Jessamine E Hazlewood, Ken-Ichi Shibasaki, Kenta Takahashi, Yuko Sato, Bing Tang, Kexin Yan, Naoko Katsuta …

Viruses, 13(9), Sep 11, 2021
Attenuated infection by a Pteropine orthoreovirus isolated from an Egyptian fruit bat in Zambia.

Hayato Harima, Michihito Sasaki, Yasuko Orba, Kosuke Okuya, Yongjin Qiu, Christida E Wastika, Katendi Changula, Masahiro Kajihara, Edgar Simulundu, Tomoyuki Yamaguchi …

PLoS neglected tropical diseases, 15(9) e0009768, Sep, 2021
Neuroinvasiveness of the MR766 strain of Zika virus in IFNAR-/- mice maps to prM residues conserved amongst African genotype viruses.

Eri Nakayama, Fumihiro Kato, Shigeru Tajima, Shinya Ogawa, Kexin Yan, Kenta Takahashi, Yuko Sato, Tadaki Suzuki, Yasuhiro Kawai, Takuya Inagaki …

PLoS pathogens, 17(7) e1009788, Jul 26, 2021
M segment-based minigenome system of severe fever with thrombocytopenia syndrome virus as a tool for antiviral drug screening

Hiroshi Yamada, Satoshi Taniguchi, Masayuki Shimojima, Long Tan, Miyuki Kimura, Yoshitomo Morinaga, Takasuke Fukuhara, Yoshiharu Matsuura, Takashi Komeno, Yousuke Furuta …

Viruses, 13(6), Jun, 2021
Characterization of pseudotyped vesicular stomatitis virus bearing the heartland virus envelope glycoprotein.

Miyuki Kimura, Kazutaka Egawa, Tatsuhiko Ozawa, Hiroyuki Kishi, Masayuki Shimojima, Satoshi Taniguchi, Shuetsu Fukushi, Hikaru Fujii, Hiroshi Yamada, Long Tan …

Virology, 556 124-132, Apr, 2021
A highly attenuated vaccinia virus strain LC16m8-based vaccine for severe fever with thrombocytopenia syndrome.

Tomoki Yoshikawa, Satoshi Taniguchi, Hirofumi Kato, Naoko Iwata-Yoshikawa, Hideki Tani, Takeshi Kurosu, Hikaru Fujii, Natsumi Omura, Miho Shibamura, Shumpei Watanabe …

PLoS pathogens, 17(2) e1008859, Feb, 2021
Activation of platelet-derived growth factor receptor β in the severe fever with thrombocytopenia syndrome virus infection.

Hideki Tani, Miyuki Kimura, Hiroshi Yamada, Hikaru Fujii, Satoshi Taniguchi, Masayuki Shimojima, Shuetsu Fukushi, Shigeru Morikawa, Masayuki Saijo

Antiviral research, 182 104926-104926, Oct, 2020
Analysis of the Function of the Lymphocytic Choriomeningitis Virus S Segment Untranslated Region on Growth Capacity In Vitro and on Virulence In Vivo.

Satoshi Taniguchi, Tomoki Yoshikawa, Masayuki Shimojima, Shuetsu Fukushi, Takeshi Kurosu, Hideki Tani, Aiko Fukuma, Fumihiro Kato, Eri Nakayama, Takahiro Maeki …

Viruses, 12(8), Aug 16, 2020 Peer-reviewed

Misc.

Inhibition of Lujo virus infection by cannabinoid receptor 1 antagonists

木村美幸, 木村美幸, 谷口怜, 谷口怜, 丸山隼輝, PAESSLER Slobodan, 谷英樹, 谷英樹, 谷英樹

日本ウイルス学会学術集会プログラム・予稿集(Web), 70th, 2023
日本で2019年以降に報告された日本脳炎患者から検出された日本脳炎ウイルスの遺伝子型はI型であった

前木孝洋, 田島茂, 中山絵里, 勝田奈穂子, 柴崎謙一, 谷口怜, 林昌宏, 西條政幸, 海老原秀喜

Neuroinfection (Web), 27(2), 2022
Characterization of a Nelson Bay orthoreovirus isolated from an Egyptian fruit bat in Zambia

播磨勇人, 佐々木道仁, 大場靖子, 邱永晋, チャングラカテンディ, 梶原将大, シムルンドゥエドガー, 谷口怜, 高田礼人, 西條政幸 …

日本ウイルス学会学術集会プログラム・予稿集(Web), 68th, 2021
Investigation of an orthoreovirus isolated from a fruit bat in Zambia

播磨勇人, 佐々木道仁, 大場靖子, QIU Yongjin, 梶原将大, 谷口怜, 高田礼人, 西條政幸, 澤洋文

日本分子生物学会年会プログラム・要旨集(Web), 44th, 2021
特徴的な皮疹から診断に至ったデング熱の1例

吉田杏子, 伊崎聡志, 清水佳祐, 藤田英樹, 照井正, 田島茂, 前木孝洋, 谷口怜, 西條政幸, 林昌宏

日本皮膚科学会雑誌, 130(4) 639-639, Apr, 2020 Peer-reviewed
抗チクングニア抗体に先行して、抗核抗体が320倍に上昇したチクングニア熱の1例

池内和彦, 安達英輔, 林阿英, 古賀道子, 堤武也, 林昌宏, 西條政幸, 四柳宏, 前木孝洋, 田島茂 …

感染症学雑誌, 94(2) 254-254, Mar, 2020
抗チクングニア抗体に先行して、抗核抗体が320倍に上昇したチクングニア熱の1例

池内和彦, 安達英輔, 林阿英, 古賀道子, 堤武也, 林昌宏, 西條政幸, 四柳宏, 前木孝洋, 田島茂 …

感染症学雑誌, 94(2) 254-254, Mar, 2020 Peer-reviewed
5年ぶりに確認された日本国内で感染したデング熱の3例

西村光司, 金澤剛二, 森岡一朗, 林昌宏, 田島茂, 前木孝洋, 中山絵里, 谷口怜, 西條政幸

IASR (Web), 41(6), 2020
デング熱ワクチンの現状と展望

前木孝洋, 中山絵里, 谷口怜, 田島茂, 林昌宏, 西條政幸

IASR (Web), 41(6), 2020
デング熱の流行状況

中山絵里, 前木孝洋, 谷口怜, 田島茂, 林昌宏, 西條政幸

IASR (Web), 41(6), 2020
2014年に国内感染例として発表されている,兵庫県西宮市でのデングウイルス1型によるデング熱患者について

田島茂, 中山絵里, 前木孝洋, 谷口怜, 林昌宏, 西條政幸

IASR (Web), 41(6), 2020
in vitroおよびin vivoにおけるハートランドウイルス感染に対するリバビリンおよびファビピラビルの効果の検証

藤井ひかる, 谷英樹, 江川和孝, 谷口怜, 吉河智城, 林昌宏, 伊藤睦代[高山], 前木孝洋, 黒須剛, 福士秀悦 …

日本獣医学会学術集会講演要旨集, 162回 404-404, Aug, 2019
デング熱と診断された日本人渡航者の血清の,デングウイルス以外のフラビウイルスへの交差反応の解析

前木孝洋, 田島茂, 池田真紀子, 加藤文博, 谷口怜, 中山絵里, 高崎智彦, 林昌宏, 西條政幸

日本ウイルス学会学術集会プログラム・予稿集(Web), 67th, 2019
重症熱性血小板減少症候群ウイルスの細胞侵入因子を同定するためのcDNAライブラリーの新規スクリーニング法

下島昌幸, 杉元聡子, 杉元聡子, 谷口怜, 吉河智城, 黒須剛, 西條政幸

日本ウイルス学会学術集会プログラム・予稿集(Web), 67th, 2019
一回感染性重症熱性血小板減少症候群ウイルスの作製

譚龍, 山田博司, 木村美幸, 谷口怜, 下島昌幸, 福士秀悦, 森川茂, 西條政幸, 谷英樹

日本ウイルス学会学術集会プログラム・予稿集(Web), 67th, 2019
遺伝子型V型日本脳炎ウイルス(GV JEV)E蛋白質123位のヒスチジン残基は,GV JEVのマウス高病原性と関連する

田島茂, 柴崎謙一, 谷口怜, 前木孝洋, 中山絵里, 林昌宏, 西條政幸

日本ウイルス学会学術集会プログラム・予稿集(Web), 67th, 2019
ミニゲノムを用いた重症熱性血小板減少症候群ウイルスのゲノム複製・転写を抑制する低分子化合物のスクリーニング

山田博司, 木村美幸, 龍龍, 谷口怜, 下島昌幸, 福原崇介, 松浦善治, 米納孝, 中嶋希, 古田要介 …

日本ウイルス学会学術集会プログラム・予稿集(Web), 67th, 2019
日本脳炎,ダニ媒介脳炎,ウエストナイル熱/脳炎,ジカウイルス病におけるフラビウイルス脳炎の鑑別

林昌宏, 前木孝洋, 田島茂, 谷口怜, 西條政幸

IASR (Web), 40(6), 2019
日本脳炎患者血清の、ウエストナイルウイルスおよびダニ媒介脳炎ウイルスへの交差反応の解析

前木孝洋, 田島茂, 池田真紀子, 加藤文博, 谷口怜, 中山絵里, 林昌宏, 高崎智彦, 西條政幸

NEUROINFECTION, 23(2) 210-210, Oct, 2018
日本脳炎患者血清の、ウエストナイルウイルスおよびダニ媒介脳炎ウイルスへの交差反応の解析

前木孝洋, 田島茂, 池田真紀子, 加藤文博, 谷口怜, 中山絵里, 林昌宏, 高崎智彦, 西條政幸

NEUROINFECTION, 23(2) 210-210, Oct, 2018

Presentations

I型インターフェロン受容体欠損マウスにおけるハートランドウイルスの感受性解析

藤井ひかる, 吉河智城, 谷口怜, 福士秀悦, 下島昌幸, 山田壮一, 谷英樹, 宇田晶彦, 前木孝洋, 原田志津子, 林昌弘, 森川茂, 西條政幸

日本獣医学会学術集会講演要旨集, Sep, 2022, (公社)日本獣医学会

Professional Memberships

Research Projects

Determination of T-B cell epitope for the development of novel anti-flavivirus therapeutic antibodies and contribution to a better understanding of pathogenesis

Grants-in-Aid for Scientific Research, Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2024 - Mar, 2027
ハートランドウイルスの非構造蛋白質の解析とバンダウイルス感染症の制圧にむけた研究

科学研究費助成事業, 基盤研究(C), 日本学術振興会, Apr, 2023 - Mar, 2026

谷口怜
Development of animal model of Zika virus infection and identification of Zika virus receptors

Grants-in-Aid for Scientific Research Grant-in-Aid for Early-Career Scientists, Grant-in-Aid for Early-Career Scientists, Japan Society for the Promotion of Science, Apr, 2018 - Mar, 2021

Taniguchi Satoshi
Pathogenicity of a novel bunyavirus STB virus

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (C), Grant-in-Aid for Scientific Research (C), Japan Society for the Promotion of Science, Apr, 2016 - Mar, 2019

Shimojima Masayuki, Sugimoto Satoko
Establishment of reverse genetics system for SFTS virus and its application for high throughput drug screening system and functional analysis of the viral proteins of SFTS virus

Grants-in-Aid for Scientific Research Grant-in-Aid for Young Scientists (B), Grant-in-Aid for Young Scientists (B), Japan Society for the Promotion of Science, Apr, 2015 - Mar, 2018

Taniguchi Satoshi
General evaluation of bats as reservoir of zoonosis in the Philippines

Grants-in-Aid for Scientific Research Grant-in-Aid for Scientific Research (B), Grant-in-Aid for Scientific Research (B), Japan Society for the Promotion of Science, Apr, 2013 - Mar, 2017

Kyuwa Shigeru, YOSHIKAWA Yasuhiro, AKASHI Hiroomi, UNE Yumi, MAEDA Ken
出血熱ウイルスの疫学的研究及び病態生理学的研究

科学研究費助成事業特別研究員奨励費, 特別研究員奨励費, 日本学術振興会, 2011 - 2013

谷口怜

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