J-GLOBAL         Last updated: Mar 1, 2019 at 10:58
Yokohama City University
School of Medicine Medical Course , Medical Science and Cardiorenal Medicine Graduate School of Medicine Degree Program

Research Areas


Academic & Professional Experience

Associate Professor, Yokohama City University 

Awards & Honors

Nov 2018
President of 5th JSVMR, Japan Society of Vascular Medicine and Rheology
Sep 2017
Umehara Award, Yokohama Foundation of Advancement of Medical Science
May 2017
Grant-in-Aid for Scientific Research, JST
Apr 2016
YCU GP, Yokohama City University
Apr 2016
Best Teacher Award, Yokohama City University

Published Papers

Taguchi Y, Matsushita K, Ishikawa T, Matsumoto K, Hosoda J, Iguchi K, Matsushita H, Kubota K, Sumita S, Ishigami T, Tamura K
Journal of cardiology      Jan 2019   [Refereed]
Nakamori H, Yoshida SI, Ishiguro H, Suzuki S, Yasuzaki H, Hashimoto T, Ishigami T, Hirawa N, Toya Y, Umemura S, Tamura K
Clinical and experimental nephrology   22(4) 773-781   Aug 2018   [Refereed]
Tanaka R, Umemura M, Narikawa M, Fujita T, Yokoyama U, Ishigami T, Kimura K, Tamura K, Ishikawa Y
Physiological reports   6(9) e13687   May 2018   [Refereed]
Doi H, Ishigami T, Nakashima-Sasaki R, Kino T, Chen L, Arakawa K, Teranaka S, Minegishi S, Abe K, Ishikawa T, Sugano T, Tamura K
Clinical and experimental hypertension (New York, N.Y. : 1993)   1-7   May 2018   [Refereed]
Narikawa M, Umemura M, Tanaka R, Fujita T, Yokoyama U, Ishigami T, Kimura K, Tamura K, Ishikawa Y
Scientific reports   8(1) 6277   Apr 2018   [Refereed]


Naoaki Ichihara, Tomoaki Ishigami, Satoshi Umemura
Journal of Cardiology   65 178-184   Jan 2015
© 2014. Background: Chronic kidney disease (CKD) alters dose-effect relationship not only of drugs eliminated by the kidney but also of some drugs metabolized by the liver and not renally excreted. It is not known whether impaired renal function a...
Junya Hosoda, Junya Hosoda, Toshiyuki Ishikawa, Toshiyuki Ishikawa, Shinichi Sumita, Shinichi Sumita, Kohei Matsushita, Kohei Matsushita, Katsumi Matsumoto, Katsumi Matsumoto, Yuichiro Kimura, Yuichiro Kimura, Yutaka Ogino, Yutaka Ogino, Yuka Taguchi, Yuka Taguchi, Hirooki Matsushita, Hirooki Matsushita, Takeshi Nakagawa, Takeshi Nakagawa, Teruyasu Sugano, Teruyasu Sugano, Tomoaki Ishigami, Tomoaki Ishigami, Kazuo Kimura, Kazuo Kimura, Satoshi Umemura, Satoshi Umemura
Circulation Journal   79 1263-1268   Jan 2015
© 2015, Japanese Circulation Society. All rights reserved. Background: The incidence of atrioventricular block (AVB) in pacemaker patients with sick sinus syndrome (SSS) is not yet known. The aim of this study was to analyze AVB episodes in SafeR ...
Masayoshi Kiyokuni, Masaaki Konishi, Kentaro Sakamaki, Chika Kawashima, Masatoshi Narikawa, Hiroshi Doi, Kiwamu Iwata, Sakie Tomari, Naoki Nakayama, Naohiro Komura, Takayuki Mitsuhashi, Hideto Yano, Teruyasu Sugano, Tomoaki Ishigami, Tsutomu Endo, Toshiyuki Ishikawa, Takeharu Yamanaka, Kazuo Kimura
International Journal of Cardiology   221 321-326   Oct 2016
© 2016Background An early IV beta blocker during primary percutaneous coronary intervention (PCI) has been shown to reduce infarct size in ST-segment elevation acute myocardial infarction (STEMI), although the underlying mechanism is unknown. The ...
Tomoaki Ishigami
Japanese Journal of Clinical Pharmacology and Therapeutics   46 35-38   Jan 2015
Junya Hosoda, Toshiyuki Ishikawa, Kohei Matsushita, Katsumi Matsumoto, Teruyasu Sugano, Tomoaki Ishigami, Kazuo Kimura, Satoshi Umemura
Circulation Journal   78 1846-1850   Jan 2014
Background: Obstruction of the access vein is a well-known complication after cardiovascular implantable electronic device (CIED) implantation. In that case, well-developed collateral superficial veins are frequently observed on the skin surface a...

Research Grants & Projects

Tubular Mechanism for Development of Salt Sensitivity and Hypertension
Ministry of Education, Culture, Sports, Science and Technology: Grant-in-Aid for Scientific Research
Project Year: Apr 2017 - Mar 2020    Investigator(s): ISHIGAMI Tomoaki
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2011 - 2013    Investigator(s): Tomoaki ISHIGAMI
Our research revealed the genetic and biological significance of molecules involved in "Molecular pathogenesis of tubular mechanisms leading to salt-sensitive hypertension." Renal tubular epithelial cells, joined by tight junction with each other,...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2008 - 2010    Investigator(s): Tomoaki ISHIGAMI
Nedd4L has been paid attention for its unique ubiquitinating properties that does an important working to cuticle sodium channel (ENaC) in the tubular epithelial cell and the post-transcriptional modification so far. Clarification and study result...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(C))
Project Year: 2006 - 2007    Investigator(s): Tomoaki ISHIGAMI
Net sodium balances in humans are maintained through various ion transporters expressed along the entire nephron. Among these ion transporters, epithelial sodium channels (ENaC) located along the aldosterone-sensitive distal nephron(ASDN)play a pi...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(基盤研究(A))
Project Year: 1996 - 1998    Investigator(s): 石井 當男, Satoshi UMEMURA
To clarify the role of renin angiotensin system (RAS) in the regulation of circulating system, in vivo and in vitro studies were performed using angiotensinogen gene knockout mice (Atg ィイD1-ィエD1/ィイD2-ィエD2 ) and it's control mice (Atg ィイD1+ィエD1/ィイD...


特願2016-204783 : Anti Atherosclerotic Agents and Diagnostic Procedures for Atherosclerosis