ICHINOSE Kunihiro

J-GLOBAL         Last updated: Jul 24, 2019 at 18:31
 
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Name
ICHINOSE Kunihiro
Affiliation
Nagasaki University
Research funding number
60437895
ORCID ID
0000-0001-8794-7106

Academic & Professional Experience

 
Sep 2008
 - 
Jun 2011
Beth Israel Deaconess Medical Center (BIDMC)
 

Published Papers

 
Toyama S, Takatani A, Koga T, Eguchi M, Okamoto M, Tsuji S, Endo Y, Shimizu T, Sumiyoshi R, Igawa T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Furuyama M, Tabuchi M, Kobayashi S, Kanetaka K, Hashisako M, Abe K, Niino D, Sato S, Miyazaki Y, Kawakami A
Internal medicine (Tokyo, Japan)      Jul 2019   [Refereed]
Koga T, Ichinose K, Kawakami A, Tsokos GC
Expert review of clinical immunology   15(6) 629-637   Jun 2019   [Refereed]
Iwamoto N, Okamoto M, Tsuji S, Endo Y, Takatani A, Shimizu T, Umeda M, Fukui S, Sumiyoshi R, Igawa T, Koga T, Kawashiri SY, Aramaki T, Ichinose K, Tamai M, Nakamura H, Origuchi T, Eguchi K, Ueki Y, Kawakami A
Journal of bone and mineral metabolism   37(3) 554-562   May 2019   [Refereed]
Fukui S, Iwamoto N, Takatani A, Igawa T, Shimizu T, Umeda M, Nishino A, Koga T, Kawashiri SY, Tamai M, Ichinose K, Nakamura H, Origuchi T, Sato S, Kawakami A
International journal of rheumatic diseases   22(5) 789-796   May 2019   [Refereed]
Koga T, Sato T, Furukawa K, Morimoto S, Endo Y, Umeda M, Sumiyoshi R, Fukui S, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Origuchi T, Nakamura H, Kawakami A
Arthritis & rheumatology (Hoboken, N.J.)   71(5) 766-772   May 2019   [Refereed]
Otsuka M, Koga T, Sumiyoshi R, Okamoto M, Endo Y, Tsuji S, Takatani A, Shimizu T, Igawa T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Daisuke N, Kawakami A
Medicine   98(18) e15237   May 2019   [Refereed]
Kawashiri SY, Fujikawa K, Nishino A, Takatani A, Shimizu T, Umeda M, Fukui S, Igawa T, Koga T, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Mizokami A, Maeda T, Kawakami A
International journal of rheumatic diseases   22(5) 842-851   May 2019   [Refereed]
Eguchi K, Iwanaga M, Terada K, Aramaki T, Tuji Y, Kurushima S, Kojima K, Arima K, Iwamoto N, Ichinose K, Kawakami A, Hirakata N, Ueki Y
Modern rheumatology      Apr 2019   [Refereed]
Otsuka M, Koga T, Sumiyoshi R, Koike Y, Furukawa K, Okamoto M, Endo Y, Tsuji S, Takatani A, Shimizu T, Igawa T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Daisuke N, Kawakami A
Immunological medicine   42(1) 45-49   Mar 2019   [Refereed]
Umetsu A, Shimizu T, Iwamoto N, Hashiguchi K, Eguchi M, Okamoto M, Endo Y, Tsuji S, Takatani A, Igawa T, Sumiyoshi R, Koga T, Kawashiri SY, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A
Internal medicine (Tokyo, Japan)   58(6) 861-864   Mar 2019   [Refereed]
Otsuka M, Koga T, Sumiyoshi R, Furukawa K, Okamoto M, Endo Y, Tsuji S, Takatani A, Shimizu T, Igawa T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A
Clinical immunology (Orlando, Fla.)   200 64-65   Mar 2019   [Refereed]
Kawashiri SY, Fujikawa K, Nishino A, Takatani A, Shimizu T, Umeda M, Fukui S, Igawa T, Koga T, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Kawakami A
International journal of rheumatic diseases      Mar 2019   [Refereed]
Shimizu T, Iwamoto N, Okamoto M, Endo Y, Tsuji S, Takatani A, Igawa T, Umeda M, Fukui S, Sumiyoshi R, Kitamura M, Koga T, Kawashiri SY, Ichinose K, Tamai M, Nakamura H, Origuchi T, Nishino T, Kawakami A
Internal medicine (Tokyo, Japan)   58(3) 441-445   Feb 2019   [Refereed]
Baba M, Ichinose K, Tamai M, Kawakami A, Ohyama K
Rheumatology international   39(2) 323-325   Feb 2019   [Refereed]
Aikawa E, Shimizu T, Koga T, Endo Y, Umeda M, Hori T, Irie J, Kuroda K, Eguchi M, Okamoto M, Tsuji S, Takatani A, Igawa T, Sumiyoshi R, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A
Internal medicine (Tokyo, Japan)      Feb 2019   [Refereed]
Ichinose K, Kitamura M, Sato S, Eguchi M, Okamoto M, Endo Y, Tsuji S, Takatani A, Shimizu T, Umeda M, Fukui S, Sumiyoshi R, Koga T, Kawashiri S, Kawakami A
Lupus      Feb 2019   [Refereed]
Fukui S, Kuwahara-Takaki A, Ono N, Sato S, Koga T, Kawashiri SY, Iwanaga N, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Migita K, Arinobu Y, Niiro H, Tada Y, Akashi K, Maeda T, Kawakami A
Scientific reports   9(1) 688   Jan 2019   [Refereed]
Ichinose K, Kitamura M, Sato S, Fujikawa K, Horai Y, Matsuoka N, Tsuboi M, Nonaka F, Shimizu T, Fukui S, Umeda M, Koga T, Kawashiri S, Iwamoto N, Kawakami A
Lupus      Jan 2019   [Refereed]
Ichinose K, Umeda M, Koga T, Kawakami A
Clinical immunology (Orlando, Fla.)   200 35-36   Jan 2019   [Refereed]
Fujita Y, Fukui S, Suzuki T, Ishida M, Endo Y, Tsuji S, Takatani A, Igawa T, Shimizu T, Umeda M, Sumiyoshi R, Nishino A, Koga T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Abe K, Kawakami A
Internal medicine (Tokyo, Japan)   57(23) 3473-3478   Dec 2018   [Refereed]
Koga T, Matoba M, Sato T, Koike Y, Endo Y, Sumiyoshi R, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A
Clinical immunology (Orlando, Fla.)   197 107-109   Dec 2018   [Refereed]
Kawashiri SY, Origuchi T, Umeda M, Nishino A, Shimizu T, Fukui S, Koga T, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Maeda T, Kawano M, Yamamoto M, Izumi Y, Kawakami A
Arthritis research & therapy   20(1) 277   Dec 2018   [Refereed]
Endo Y, Koga T, Eguchi M, Okamoto M, Tsuji S, Takatani A, Shimizu T, Sumiyoshi R, Igawa T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A
Medicine   97(51) e13295   Dec 2018   [Refereed]
Umeda M, Koga T, Ichinose K, Takatani A, Igawa T, Shimizu T, Fukui S, Nishino A, Horai Y, Hirai Y, Kawashiri SY, Iwamoto N, Tamai M, Nakamura H, Origuchi T, Aramaki T, Ueki Y, Okada A, Fujikawa K, Matsuoka N, Kawakami A
Immunological medicine   41(4) 181-186   Dec 2018   [Refereed]
Ichinose K, Kitamura M, Sato S, Fujikawa K, Horai Y, Matsuoka N, Tsuboi M, Nonaka F, Shimizu T, Fukui S, Umeda M, Koga T, Kawashiri SY, Iwamoto N, Igawa T, Tamai M, Nakamura H, Origuchi T, Nishino T, Kawakami A
Clinical immunology (Orlando, Fla.)   197 161-168   Dec 2018   [Refereed]
Aramaki T, Ueki Y, Kojima K, Kurushima S, Tsuji Y, Kawachi N, Iwamoto N, Ichinose K, Terada K, Eguchi K, Kawakami A
Modern rheumatology   1-18   Nov 2018   [Refereed]
Endo Y, Koga T, Ishida M, Fujita Y, Tsuji S, Takatani A, Shimizu T, Sumiyoshi R, Igawa T, Umeda M, Fukui S, Nishino A, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Agematsu K, Yachie A, Masumoto J, Migita K, Kawakami A
Arthritis research & therapy   20(1) 257   Nov 2018   [Refereed]
Fujita Y, Fukui S, Ishida M, Endo Y, Tsuji S, Takatani A, Igawa T, Shimizu T, Umeda M, Sumiyoshi R, Nishino A, Koga T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A
Internal medicine (Tokyo, Japan)   57(20) 3025-3028   Oct 2018   [Refereed]
Aibara N, Ichinose K, Baba M, Nakajima H, Satoh K, Atarashi R, Kishikawa N, Nishida N, Kawakami A, Kuroda N, Ohyama K
Clinica chimica acta; international journal of clinical chemistry   484 26-31   Sep 2018   [Refereed]
Hara K, Endo Y, Ishida M, Fujita Y, Tsuji S, Takatani A, Shimizu T, Sumiyoshi R, Igawa T, Umeda M, Fukui S, Nishino A, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Migita K, Kawakami A, Koga T
Medicine   97(38) e12305   Sep 2018   [Refereed]
Iwamoto N, Fukui S, Takatani A, Shimizu T, Umeda M, Nishino A, Igawa T, Koga T, Kawashiri SY, Ichinose K, Tmai M, Nakamura H, Origuchi T, Chiba K, Osaki M, Jüngel A, Gay S, Kawakami A
Arthritis research & therapy   20(1) 189   Aug 2018   [Refereed]
Maeda K, Otomo K, Yoshida N, Abu-Asab MS, Ichinose K, Nishino T, Kono M, Ferretti A, Bhargava R, Maruyama S, Bickerton S, Fahmy TM, Tsokos MG, Tsokos GC
The Journal of clinical investigation   128(8) 3445-3459   Aug 2018   [Refereed]
Koga T, Umeda M, Endo Y, Ishida M, Fujita Y, Tsuji S, Takatani A, Shimizu T, Sumiyoshi R, Igawa T, Fukui S, Nishino A, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Murakami N, Kitajima M, Kawakami A
International journal of rheumatic diseases   21(6) 1287-1292   Jun 2018   [Refereed]
Endo Y, Koga T, Ishida M, Fujita Y, Tsuji S, Takatani A, Shimizu T, Sumiyoshi R, Igawa T, Umeda M, Fukui S, Nishino A, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kuwana M, Hosono Y, Mimori T, Kawakami A
Medicine   97(26) e11024   Jun 2018   [Refereed]
Tomohiro Koga, Tomohiro Koga, Kiyoshi Migita, Tomohito Sato, Shuntaro Sato, Masataka Umeda, Fumiaki Nonaka, Fumiaki Nonaka, Shoichi Fukui, Shin Ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Yukitaka Ueki, Junya Masumoto, Kazunaga Agematsu, Akihiro Yachie, Koh Ichiro Yoshiura, Katsumi Eguchi, Atsushi Kawakami
Rheumatology (United Kingdom)   57 718-726   Apr 2018
© The Author(s) 2018. Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved. Objective. We sought to identify the microRNA (miRNA) profile and potential biomarkers in FMF and to clarify their g...
Yushiro Endo, Tomohiro Koga, Takahisa Suzuki, Kazusato Hara, Midori Ishida, Yuya Fujita, Sosuke Tsuji, Ayuko Takatani, Toshimasa Shimizu, Remi Sumiyoshi, Takashi Igawa, Masataka Umeda, Shoichi Fukui, Ayako Nishino, Shin Ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Masataka Kuwana, Atsushi Kawakami
Medicine (United States)   97    Apr 2018
Copyright © 2018 the Author(s). Published by Wolters Kluwer Health, Inc. Rationale: As the initial treatment of rapidly progressive interstitial lung disease (RPILD) with antimelanoma differentiationassociated gene 5 antibody (anti-MDA5 Ab)-positi...
Prediction of organ involvement in systemic sclerosis by serum biomarkers and peripheral endothelial function.
Kawashiri SY, Nishino A, Igawa T, Takatani A, Shimizu T, Umeda M, Fukui S, Okada A, Suzuki T, Koga T, Iwamoto N, Ichinose K, Tamai M, Nakashima M, Mizokami A, Matsuoka N, Migita K, Ogawa F, Ikeda S, Maemura K, Nakamura H, Origuchi T, Maeda T, Kawakami A
Clinical and experimental rheumatology      Apr 2018   [Refereed]
Endo Y, Koga T, Ishida M, Fujita Y, Tsuji S, Takatani A, Shimizu T, Sumiyoshi R, Igawa T, Umeda M, Fukui S, Nishino A, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Kawakami A
Internal medicine (Tokyo, Japan)      Mar 2018   [Refereed]
Tomonori Ishii, Yoshiya Tanaka, Atsushi Kawakami, Kazuyoshi Saito, Kunihiro Ichinose, Hiroshi Fujii, Yuko Shirota, Tsuyoshi Shirai, Yoko Fujita, Ryu Watanabe, Shih Wei Chiu, Takuhiro Yamaguchi, Hideo Harigae
Modern Rheumatology   1-7   Feb 2018
© 2018 Japan College of Rheumatology Objectives: The objective of this study is to evaluate the efficacy and safety of bortezomib for treating systemic lupus erythematosus (SLE), in patients whose disease activity could not be controlled. Methods:...
Masataka Umeda, Tomohiro Koga, Tomohiro Koga, Kunihiro Ichinose, Takashi Igawa, Tomohito Sato, Ayuko Takatani, Toshimasa Shimizu, Shoichi Fukui, Ayako Nishino, Yoshiro Horai, Yoshiro Horai, Yasuko Hirai, Shin ya Kawashiri, Naoki Iwamoto, Toshiyuki Aramaki, Mami Tamai, Hideki Nakamura, Kazuo Yamamoto, Norio Abiru, Tomoki Origuchi, Yukitaka Ueki, Atsushi Kawakami
Clinical Immunology   187 50-57   Feb 2018
© 2017 Elsevier Inc. The cell-surface glycoprotein CD52 is widely expressed in lymphocytes. CD4 + CD52 hi T cells are functioning suppressor CD4 + T cells. We investigated the role of the immune regulation of CD4 + CD52 T cells in systemic lupus e...
Suzuki T, Fukui S, Umekita K, Miyamoto J, Umeda M, Nishino A, Okada A, Koga T, Kawashiri SY, Iwamoto N, Ichinose K, Tamai M, Fujikawa K, Aramaki T, Mizokami A, Matsuoka N, Ueki Y, Eguchi K, Sato S, Hidaka T, Origuchi T, Okayama A, Kawakami A, Nakamura H
Arthritis & rheumatology (Hoboken, N.J.)      Feb 2018   [Refereed]
Nishino A, Kawashiri SY, Koga T, Iwamoto N, Ichinose K, Tamai M, Nakamura H, Origuchi T, Ueki Y, Yoshitama T, Eiraku N, Matsuoka N, Okada A, Fujikawa K, Hamada H, Tsuru T, Nagano S, Arinobu Y, Hidaka T, Kawakami A
Arthritis care & research      Feb 2018   [Refereed]
Shoichi Fukui, Shoichi Fukui, Naoki Iwamoto, Ayuko Takatani, Takashi Igawa, Toshimasa Shimizu, Masataka Umeda, Masataka Umeda, Ayako Nishino, Ayako Nishino, Yoshiro Horai, Yoshiro Horai, Yasuko Hirai, Tomohiro Koga, Tomohiro Koga, Shin Ya Kawashiri, Shin Ya Kawashiri, Mami Tamai, Kunihiro Ichinose, Hideki Nakamura, Tomoki Origuchi, Tomoki Origuchi, Ritsuko Masuyama, Kosuke Kosai, Katsunori Yanagihara, Atsushi Kawakami
Frontiers in Immunology   8    Jan 2018
© 2018 Fukui, Iwamoto, Takatani, Igawa, Shimizu, Umeda, Nishino, Horai, Hirai, Koga, Kawashiri, Tamai, Ichinose, Nakamura, Origuchi, Masuyama, Kosai, Yanagihara and Kawakami. Objectives: We investigated the relationships among M1 monocytes, M2 mon...
Chiaki Watanabe, Shoichi Fukui, Naoki Iwamoto, Toshimasa Shimizu, Masataka Umeda, Ayako Nishino, Tomohiro Koga, Shin Ya Kawashiri, Shin Ya Kawashiri, Kunihiro Ichinose, Yasuko Hirai, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Tomoki Origuchi, Kazuhiro Tabata, Atsushi Kawakami
Internal Medicine   57 417-421   Jan 2018
© 2018 The Japanese Society of Internal Medicine. A 65-year-old man was diagnosed with granulomatosis with polyangiitis (GPA) based on the detection of high myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA), vasculitis and granulomas...
Masataka Umeda, Kunihiro Ichinose, Ayako Nishino, Akitomo Okada, Shin Ya Kawashiri, Naoki Iwamoto, Mami Tamai, Hideki Nakamura, Tomoki Origuchi, Hitomi Minami, Naoe Kinoshita, Fuminao Takeshima, Atsushi Kawakami
International Journal of Rheumatic Diseases   21 566-570   Jan 2018
Tomohiro Koga, Kunihiro Ichinose, George C. Tsokos
Clinical Immunology   185 95-99   Dec 2017
© 2016 Elsevier Inc. Systemic lupus erythematosus (SLE) is a complicated autoimmune disorder characterized by autoantibodies production, immune complex formation, and immune dysregulation, resulting in damage of multiple organs including the kidne...
Kenji Oku, Tatsuya Atsumi, Yuji Akiyama, Hirofumi Amano, Naoto Azuma, Toshiyuki Bohgaki, Yu Funakubo Asanuma, Tetsuya Horita, Tadashi Hosoya, Kunihiro Ichinose, Masaru Kato, Yasuhiro Katsumata, Yasushi Kawaguchi, Atsushi Kawakami, Tomohiro Koga, Hitoshi Kohsaka, Yuya Kondo, Kanae Kubo, Masataka Kuwana, Akio Mimori, Tsuneyo Mimori, Toshihide Mimura, Kosaku Murakami, Kazuhisa Nakano, Shingo Nakayamada, Hiroshi Ogishima, Kazumasa Ohmura, Kazuyoshi Saito, Hajime Sano, Mihoko Shibuya, Yuko Takahashi, Yoshinari Takasaki, Tsutomu Takeuchi, Naoto Tamura, Yoshiya Tanaka, Hiroto Tsuboi, Shinichiro Tsunoda, Naoichiro Yukawa, Noriyuki Yamakawa, Noriyuki Yamakawa, Kazuhiko Yamamoto, Takayuki Sumida
Modern Rheumatology   1-7   Nov 2017
© 2017 Japan College of Rheumatology Objective: To evaluate the performance of the 2012 Systemic Lupus International Collaborating Clinics criteria (SLICC-12) on classifying systemic lupus erythematosus (SLE) in an uncontrolled multi-centered stud...
Mami Tamai, Kazuhiko Arima, Yoshikazu Nakashima, Junko Kita, Masataka Umeda, Shoichi Fukui, Ayako Nishino, Takahisa Suzuki, Takahisa Suzuki, Yoshiro Horai, Akitomo Okada, Akitomo Okada, Tomohiro Koga, Shin ya Kawashiri, Shin ya Kawashiri, Naoki Iwamoto, Kunihiro Ichinose, Satoshi Yamasaki, Hideki Nakamura, Tomoki Origuchi, Tomoki Origuchi, Kiyoshi Aoyagi, Masataka Uetani, Katsumi Eguchi, Katsumi Eguchi, Atsushi Kawakami
Modern Rheumatology   27 961-966   Nov 2017
© 2017 Japan College of Rheumatology. Objective: To examine whether magnetic resonance imaging (MRI) findings at baseline predict radiographic progression in early-stage rheumatoid arthritis (RA) patients who have achieved sustained good clinical ...
Masataka Umeda, Toshiyuki Aramaki, Keita Fujikawa, Naoki Iwamoto, Kunihiro Ichinose, Kaoru Terada, Gou Takeo, Nobuhisa Yonemitsu, Yukitaka Ueki, Kiyoshi Migita, Atsushi Kawakami
International Journal of Rheumatic Diseases   20 1868-1871   Nov 2017
T. Koga, T. Koga, S. Kawashiri, S. Kawashiri, K. Migita, S. Sato, M. Umeda, M. Umeda, S. Fukui, A. Nishino, A. Nishino, F. Nonaka, F. Nonaka, N. Iwamoto, K. Ichinose, M. Tamai, H. Nakamura, T. Origuchi, Y. Ueki, J. Masumoto, K. Agematsu, A. Yachie, K. Eguchi, A. Kawakami
Scandinavian Journal of Rheumatology   1-3   Sep 2017

Misc

 
【リウマチ性疾患の神経・筋病変-clinical update 2017】 SLEの中枢神経病変
一瀬 邦弘
リウマチ科   57(5) 455-465   May 2017
【全身性エリテマトーデス:病態解明の進歩】 神経精神SLE
一瀬 邦弘
炎症と免疫   25(2) 133-138   Feb 2017
神経精神SLE(NPSLE)は患者の健康、生活の質、SLEの生命予後にも影響を与えるSLEの重篤な臓器合併症の1つである。NPSLEは中枢神経だけではなく、末梢神経、自律神経障害を引き起こし、病態・症状も複雑であるため診断・治療を困難にしている。NPSLEはさまざまな臨床症状を呈するが、病態は大きく分けて2つあると考えられている。1つ目は抗リン脂質抗体症候群、免疫複合体や炎症細胞の集簇に起因する血管障害による虚血でいわゆる限局性症状を呈するもの、2つ目は補体の活性化、血液脳関門の透過性亢進...
【キナーゼ阻害によるリウマチ性疾患の治療-現在と未来-】 CaMKIV
一瀬 邦弘, 古賀 智裕, 川上 純
分子リウマチ治療   7(4) 211-215   Oct 2014
Ca2+/calmodulin-dependent protein kinase IV(CaMKIV)はリンパ球、血球系前駆細胞、神経細胞、胸腺細胞、骨芽細胞などに広く発現しており、シグナル伝達物質として細胞の核内に移行し、さまざまな転写因子活性を有する。CaMKIV阻害薬であるKN-93はT細胞におけるIL-2やIL-17発現をコントロールし、全身性エリテマトーデス(SLE)などの自己免疫疾患の病態を制御する可能性がある。またT細胞だけではなく、抗原提示細胞や単球・マクロファージに類似し...
【最新関節リウマチ学-寛解・治癒を目指した研究と最新治療-】 関節リウマチの発症要因と発症メカニズム 発症メカニズム Th17細胞
一瀬 邦弘, 川上 純
日本臨床   72(増刊3 最新関節リウマチ学) 53-58   Apr 2014
【もっと深くエビデンスを読む】 超早期のエビデンスは PREMIER vs.COMET
川上 純, 川尻 真也, 玉井 慎美, 岩本 直樹, 一瀬 邦弘, 中村 英樹, 折口 智樹
分子リウマチ治療   5(3) 111-117   Jul 2012
2012 ACR勧告では早期関節リウマチ(RA)は発症6ヵ月以内と述べられた。これには超早期RAも含有され、関節破壊が進行しやすいが治療反応性にもすぐれ、window of opportunityの大切な時期である。この勧告では早期RAでも高疾患活動性あり、予後不良因子ありの場合は、最初からメトトレキサートとTNF阻害剤のcombination therapyが推奨されている。本稿では罹病期間が短いRAに対するcombination therapyの代表的な治験であるPREMIER試験とC...
【糖尿病腎症発症と適正管理】 血管新生抑制因子による糖尿病腎症進展制御
前島 洋平, 一瀬 邦弘, 槇野 博史
内分泌・糖尿病科   24(6) 552-560   Jun 2007
【生物学的製剤の臨床効果 現況と展望】 早期症例への積極的導入の意義
一瀬 邦弘, 川上 純, 江口 勝美
Progress in Medicine   28(1) 41-47   Jan 2008
【関節リウマチにおける生物学的製剤の実際と問題点】 アダリムマブ Premier試験の示すもの
一瀬 邦弘, 川上 純, 江口 勝美
リウマチ科   37(1) 17-21   Jan 2007
糖尿病合併症に関する最近の知見 腎症進展における糸球体上皮細胞障害の意義
前島 洋平, 一瀬 邦弘, 山本 佳彦, 槇野 博史
分子糖尿病学の進歩: 基礎から臨床まで   2006 162-167   Mar 2006

Conference Activities & Talks

 
Evaluation of soluble a-klotho in neuropsychiatric systemic lupus erythematosus.
Ushigusa T, Ichinose K, Tshuji S, Umeda M, Fukui S, Nishino A, Nakashima Y, Suzuki T, Horai Y, Koga T, Kawashiri S-Y, Iwamoto N, Hirai Y, Tamai M, Nakamura H, Origuchi T, Kawakami A.
Annual European Conguress of Rheumatology 2015   10 Jun 2015