MIYAZAKI Taiga

Last updated: Sep 9, 2019 at 18:38

Name	MIYAZAKI Taiga
Affiliation	Nagasaki University
Section	Graduate School of Biomedical Sciences
Research funding number	60448496

Research Areas

Basic medicine / Bacteriology (including mycology) /
Clinical internal medicine / Infectious disease medicine /

Published Papers

Plain Text

The Novel Arylamidine T-2307 Selectively Disrupts Yeast Mitochondrial Function by Inhibiting Respiratory Chain Complexes

Yamashita K, Miyazaki T, Fukuda Y, Mitsuyama J, Saijo T, Shimamura S, Yamamoto K, Imamura Y, Izumikawa K, Yanagihara K, Kohno S, Mukae H

Antimicrob Agents Chemother 63(8) Aug 2019 [Refereed]

Evaluation of Candida peritonitis with underlying peritoneal fibrosis and efficacy of micafungin in murine models of intra-abdominal candidiasis

Ashizawa N, Miyazaki T, Abe S, Takazono T, Saijo T, Obata Y, Shimamura S, Yamamoto K, Imamura Y, Koji T, Nishino T, Izumikawa K, Yanagihara K, Kohno S, Mukae H

Sci Rep 9(1) 9331 Jun 2019 [Refereed]

The efficacy and safety of sitafloxacin and garenoxacin for the treatment of pneumonia in elderly patients: A randomized, multicenter, open-label trial.

Miyazaki T, Nakamura S, Hashiguchi K, Kobayashi T, Fukushima K, Fukuda Y, Kondo A, Inoue Y, Koga H, Sasaki E, Nagayoshi Y, Higashiyama Y, Yoshida M, Takazono T, Saijo T, Morinaga Y, Yamamoto K, Imamura Y, Mikushi S, Izumikawa K, Yanagihara K, Kohno S, Mukae H

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy May 2019 [Refereed]

The incidence of endophthalmitis or macular involvement and the necessity of a routine ophthalmic examination in patients with candidemia.

Ueda T, Takesue Y, Tokimatsu I, Miyazaki T, Nakada-Motokawa N, Nagao M, Nakajima K, Mikamo H, Yamagishi Y, Kasahara K, Yoshihara S, Ukimura A, Yoshida K, Yoshinaga N, Izumi M, Kakeya H, Yamada K, Kawamura H, Endou K, Yamanaka K, Yoshioka M, Amino K, Ikeuchi H, Uchino M, Miyazaki Y

PloS one 14(5) e0216956 May 2019 [Refereed]

Efficacy and safety of cefditoren pivoxil for exacerbations of chronic obstructive pulmonary disease: A prospective multicenter interventional study.

Miyazaki T, Fukushima K, Hashiguchi K, Inoue Y, Mihara T, Sawai T, Suyama N, Kobayashi T, Kondo A, Fukuda Y, Harada Y, Sasaki E, Kaku N, Ide S, Takazono T, Saijo T, Kosai K, Morinaga Y, Nakamura S, Yamamoto K, Imamura Y, Izumikawa K, Yanagihara K, Kohno S, Mukae H

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy Apr 2019 [Refereed]

Selection of oral antifungals for initial maintenance therapy in chronic pulmonary aspergillosis: A longitudinal analysis.

Tashiro M, Takazono T, Saijo T, Yamamoto K, Imamura Y, Miyazaki T, Kakeya H, Ando T, Ogawa K, Kishi K, Tokimatsu I, Hayashi Y, Fujiuchi S, Yanagihara K, Miyazaki Y, Ichihara K, Mukae H, Kohno S, Izumikawa K

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America Apr 2019 [Refereed]

Clinical features and cause analysis of false positive results of Aspergillus galactomannan assay in pulmonary cryptococcosis patients.

Takazono T, Saijo T, Ashizawa N, Oshima K, Nishimura K, Tashiro M, Yamamoto K, Imamura Y, Miyazaki T, Yanagihara K, Mukae H, Izumikawa K, Sheppard DC

European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 38(4) 735-741 Apr 2019 [Refereed]

Molecular and epidemiological analysis of IMP-1 metallo-β-lactamase-producing Klebsiella pneumoniae in a tertiary care hospital in Japan.

Yamakawa H, Kosai K, Akamatsu N, Matsuda J, Kaku N, Uno N, Morinaga Y, Hasegawa H, Tsubouchi T, Kaneko Y, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 25(4) 240-246 Apr 2019 [Refereed]

A case of bilateral emphysematous pyelonephritis caused by Candida albicans.

Ideguchi S, Yamamoto K, Ikeda A, Hashimoto K, Takazono T, Saijo T, Imamura Y, Miyazaki T, Mukae H

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 25(4) 302-306 Apr 2019 [Refereed]

Evaluation of Aspergillus-specific Lateral-Flow Device Test using Serum and Bronchoalveolar Lavage Fluid for Diagnosis of Chronic Pulmonary Aspergillosis.

Takazono T, Ito Y, Tashiro M, Nishimura K, Saijo T, Yamamoto K, Imamura Y, Miyazaki T, Yanagihara K, Mukae H, Izumikawa K

Journal of clinical microbiology 57(5) Mar 2019 [Refereed]

Autophagy-Inducing Factor Atg1 Is Required for Virulence in the Pathogenic Fungus Candida glabrata.

Shimamura S, Miyazaki T, Tashiro M, Takazono T, Saijo T, Yamamoto K, Imamura Y, Izumikawa K, Yanagihara K, Kohno S, Mukae H

Frontiers in microbiology 10 27 2019 [Refereed]

Vacuolar proton-translocating ATPase is required for antifungal resistance and virulence of Candida glabrata.

Minematsu A, Miyazaki T, Shimamura S, Nishikawa H, Nakayama H, Takazono T, Saijo T, Yamamoto K, Imamura Y, Yanagihara K, Kohno S, Mukae H, Izumikawa K

PloS one 14(1) e0210883 2019 [Refereed]

Evaluation of FilmArray respiratory panel multiplex polymerase chain reaction assay for detection of pathogens in adult outpatients with acute respiratory tract infection.

Kaku N, Hashiguchi K, Iwanaga Y, Akamatsu N, Matsuda J, Kosai K, Uno N, Morinaga Y, Kitazaki T, Hasegawa H, Miyazaki T, Fukuda M, Izumikawa K, Mukae H, Yanagihara K

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 24(9) 734-738 Sep 2018 [Refereed]

Pulmonary Scedosporium apiospermum Infection with Pulmonary Tumorlet in an Immunocompetent Patient.

Motokawa N, Miyazaki T, Hara A, Fukuda Y, Morino S, Nakamura H, Iwasaki K, Soda H, Izumikawa K, Yanagihara K, Ohno H, Miyazaki Y, Kohno S, Mukae H

Internal medicine (Tokyo, Japan) 57(23) 3485-3490 Aug 2018 [Refereed]

Performance evaluation of the MALDI Biotyper Selective Testing of Antibiotic Resistance-β-Lactamase (MBT STAR-BL) assay for the detection of IMP metallo-β-lactamase activity in Enterobacteriaceae.

Kawamoto Y, Kosai K, Yamakawa H, Kaku N, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K

Diagnostic microbiology and infectious disease 92(4) 267-352 Jun 2018 [Refereed]

Clinical and Microbiological Characteristics of Candida guilliermondii and Candida fermentati.

Hirayama T, Miyazaki T, Yamagishi Y, Mikamo H, Ueda T, Nakajima K, Takesue Y, Higashi Y, Yamamoto Y, Kimura M, Araoka H, Taniguchi S, Fukuda Y, Matsuo Y, Furutani A, Yamashita K, Takazono T, Saijo T, Shimamura S, Yamamoto K, Imamura Y, Izumikawa K, Yanagihara K, Kohno S, Mukae H

Antimicrobial agents and chemotherapy 62(6) Jun 2018 [Refereed]

In Vitro Activity of Lascufloxacin against Streptococcus pneumoniae with Mutations in the Quinolone Resistance-Determining Regions.

Murata M, Kosai K, Yamauchi S, Sasaki D, Kaku N, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K

Antimicrobial agents and chemotherapy 62(4) Apr 2018 [Refereed]

Examination of cryptococcal glucuronoxylomannan antigen in bronchoalveolar lavage fluid for diagnosing pulmonary cryptococcosis in HIV-negative patients.

Oshima K, Takazono T, Saijo T, Tashiro M, Kurihara S, Yamamoto K, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Mukae H, Kohno S, Izumikawa K

Medical mycology 56(1) 88-94 Jan 2018 [Refereed]

Risk Factors for Acquisition of Fluoroquinolone or Aminoglycoside Resistance in Addition to Carbapenem Resistance in Pseudomonas aeruginosa.

Kosai K, Kaku N, Uno N, Saijo T, Morinaga Y, Imamura Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K

The open microbiology journal 12 321-322 2018 [Refereed]

Adjunctive corticosteroid therapy for inpatients with Mycoplasma pneumoniae pneumonia.

Tashiro M, Fushimi K, Kawano K, Takazono T, Saijo T, Yamamoto K, Kurihara S, Imamura Y, Miyazaki T, Yanagihara K, Mukae H, Izumikawa K

BMC pulmonary medicine 17(1) 219 Dec 2017 [Refereed]

Comparison of Efficacy of Antimicrobial Agents Among Hospitalized Patients With Mycoplasma pneumoniae Pneumonia in Japan During Large Epidemics of Macrolide-Resistant M. pneumoniae Infections: A Nationwide Observational Study.

Tashiro M, Fushimi K, Kawano K, Takazono T, Saijo T, Yamamoto K, Kurihara S, Imamura Y, Miyazaki T, Yanagihara K, Mukae H, Izumikawa K

Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 65(11) 1837-1842 Nov 2017 [Refereed]

Performance evaluation of the Verigene^®Clostridium difficile nucleic acid test, an automated multiplex molecular testing system for detection of C. difficile toxin.

Kosai K, Iwanaga Y, Akamatsu N, Okada Y, Kaku N, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 23(10) 674-677 Oct 2017 [Refereed]

A case series of histoplasmosis patients with elevated serum soluble interleukin-2 receptor levels.

Hirayama T, Takazono T, Iwata K, Senju H, Shimazaki T, Tashiro M, Saijo T, Tanaka T, Nakamura S, Imamura Y, Kojiro M, Miyazaki T, Tsukamoto M, Furumoto A, Morimoto K, Muraosa Y, Matsubara Y, Yanagihara K, Mukae H, Kamei K, Kohno S, Izumikawa K.

ournal of Infection and Chemotherapy 23(9) 642-647 Sep 2017 [Refereed]

Tedizolid inhibits MUC5AC production induced by methicillin-resistant Staphylococcus aureus in human airway epithelial cells.

Takeda K, Kaku N, Morinaga Y, Kosai K, Uno N, Imamura Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 23(9) 598-603 Sep 2017 [Refereed]

Efficacy and Pharmacokinetics of the Combination of OP0595 and Cefepime in a Mouse Model of Pneumonia Caused by Extended-Spectrum-Beta-Lactamase-Producing Klebsiella pneumoniae.

Kaku N, Kosai K, Takeda K, Uno N, Morinaga Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K

Antimicrobial agents and chemotherapy 61(7) Jul 2017 [Refereed]

Comparative efficacies of daptomycin, vancomycin, and linezolid in experimental enterococcal peritonitis.

Kajihara T, Nakamura S, Iwanaga N, Oshima K, Hirano K, Miyazaki T, Izumikawa K, Yanagihara K, Miyazaki Y, Hattori N, Kohno N, Kohno S, Mukae H

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 23(7) 498-501 Jul 2017 [Refereed]

In vitro and in vivo antifungal activities of T-2307, a novel arylamidine, against Cryptococcus gattii: an emerging fungal pathogen.

Nishikawa H, Fukuda Y, Mitsuyama J, Tashiro M, Tanaka A, Takazono T, Saijo T, Yamamoto K, Nakamura S, Imamura Y, Miyazaki T, Kakeya H, Yamamoto Y, Yanagihara K, Mukae H, Kohno S, Izumikawa K

The Journal of antimicrobial chemotherapy 72(6) 1709-1713 Jun 2017 [Refereed]

Efficacy and pharmacokinetics of ME1100, a novel optimized formulation of arbekacin for inhalation, compared with amikacin in a murine model of ventilator-associated pneumonia caused by Pseudomonas aeruginosa.

Kaku N, Morinaga Y, Takeda K, Kosai K, Uno N, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K

The Journal of antimicrobial chemotherapy 72(4) 1123-1128 Apr 2017 [Refereed]

Efficacy of High-Dose Meropenem (Six Grams per Day) in Treatment of Experimental Murine Pneumonia Induced by Meropenem-Resistant Pseudomonas aeruginosa.

Oshima K, Nakamura S, Iwanaga N, Takemoto K, Miyazaki T, Yanagihara K, Miyazaki Y, Mukae H, Kohno S, Izumikawa K

Antimicrobial agents and chemotherapy 61(1) Jan 2017 [Refereed]

Efficacy and Safety of Intravenous Peramivir Compared With Oseltamivir in High-Risk Patients Infected With Influenza A and B Viruses: A Multicenter Randomized Controlled Study.

Nakamura S, Miyazaki T, Izumikawa K, Kakeya H, Saisho Y, Yanagihara K, Miyazaki Y, Mukae H, Kohno S

Open forum infectious diseases 4(3) ofx129 2017 [Refereed]

Risk Factors for Acquisition of Fluoroquinolone or Aminoglycoside Resistance in Addition to Carbapenem Resistance in Pseudomonas Aeruginosa.

Kosai K, Kaku N, Uno N, Saijo T, Morinaga Y, Imamura Y, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K

The open microbiology journal 11 92-97 2017 [Refereed]

Pulmonary Actinomycosis Mimicking Pulmonary Aspergilloma and a Brief Review of the Literature.

Higashi Y, Nakamura S, Ashizawa N, Oshima K, Tanaka A, Miyazaki T, Izumikawa K, Yanagihara K, Yamamoto Y, Miyazaki Y, Mukae H, Kohno S

Internal medicine (Tokyo, Japan) 56(4) 449-453 2017 [Refereed]

Unexpected effects of azole transporter inhibitors on antifungal susceptibility in Candida glabrata and other pathogenic Candida species.

Nagayoshi Y, Miyazaki T, Shimamura S, Nakayama H, Minematsu A, Yamauchi S, Takazono T, Nakamura S, Yanagihara K, Kohno S, Mukae H, Izumikawa K

PloS one 12(7) e0180990 2017 [Refereed]

Antimicrobial and immunomodulatory effects of tedizolid against methicillin-resistant Staphylococcus aureus in a murine model of hematogenous pulmonary infection.

Kaku N, Morinaga Y, Takeda K, Kosai K, Uno N, Hasegawa H, Miyazaki T, Izumikawa K, Mukae H, Yanagihara K

International journal of medical microbiology : IJMM 306(6) 421-428 Sep 2016 [Refereed]

Roles of vacuolar H+-ATPase in the oxidative stress response of Candida glabrata.

Nishikawa H, Miyazaki T, Nakayama H, Minematsu A, Yamauchi S, Yamashita K, Takazono T, Shimamura S, Nakamura S, Izumikawa K, Yanagihara K, Kohno S, Mukae H

FEMS yeast research 16(5) Aug 2016 [Refereed]

The world first two cases of severe fever with thrombocytopenia syndrome: An epidemiological study in Nagasaki, Japan.

Kurihara S, Satoh A, Yu F, Hayasaka D, Shimojima M, Tashiro M, Saijo T, Takazono T, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Mukae H, Saijo M, Morita K, Kohno S, Izumikawa K

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 22(7) 461-465 Jul 2016 [Refereed]

Toll-Like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice.

Nakamura S, Iwanaga N, Seki M, Fukudome K, Oshima K, Miyazaki T, Izumikawa K, Yanagihara K, Miyazaki Y, Mukae H, Kohno S

Infection and immunity 84(7) 1986-1993 Jul 2016 [Refereed]

T-2307, a novel arylamidine, is transported into Candida albicans by a high-affinity spermine and spermidine carrier regulated by Agp2.

Nishikawa H, Sakagami T, Yamada E, Fukuda Y, Hayakawa H, Nomura N, Mitsuyama J, Miyazaki T, Mukae H, Kohno S

The Journal of antimicrobial chemotherapy 71(7) 1845-1855 Jul 2016 [Refereed]

A mortality prediction rule for non-elderly patients with community-acquired pneumonia.

Tashiro M, Fushimi K, Takazono T, Kurihara S, Miyazaki T, Tsukamoto M, Yanagihara K, Mukae H, Tashiro T, Kohno S, Izumikawa K

BMC pulmonary medicine 16 39 Mar 2016 [Refereed]

SERODIAGNOSIS OF THE MYCOBACTERIUM AVIUM COMPLEX BY USING IgA ANTIBODIES FOR THE GLYCOPEPTIDOLIPID CORE ANTIGEN.

Higashi Y, Nakamura S, Tomono H, Ide S, Takazono T, Miyazaki T, Izumikawa K, Yanagihara K, Yamamoto Y, Kohno S

Kekkaku : [Tuberculosis] 91(2) 27-32 Feb 2016 [Refereed]

The risk factors for developing of chronic pulmonary aspergillosis in nontuberculous mycobacteria patients and clinical characteristics and outcomes in chronic pulmonary aspergillosis patients coinfected with nontuberculous mycobacteria.

Takeda K, Imamura Y, Takazono T, Yoshida M, Ide S, Hirano K, Tashiro M, Saijo T, Kosai K, Morinaga Y, Nakamura S, Kurihara S, Tsukamoto M, Miyazaki T, Tashiro T, Kohno S, Yanagihara K, Izumikawa K

Medical mycology 54(2) 120-127 Feb 2016 [Refereed]

Recurrent Streptococcus agalactiae Toxic Shock Syndrome Triggered by a Tumor Necrosis Factor-α Inhibitor.

Yoshida M, Takazono T, Tashiro M, Saijo T, Morinaga Y, Yamamoto K, Nakamura S, Imamura Y, Miyazaki T, Sawai T, Nishino T, Izumikawa K, Yanagihara K, Mukae H, Kohno S

Internal medicine (Tokyo, Japan) 55(21) 3211-3214 2016 [Refereed]

Relapsed Pulmonary Cryptococcosis during Tumor Necrosis Factor α Inhibitor Treatment.

Takazono T, Sawai T, Tashiro M, Saijo T, Yamamoto K, Imamura Y, Miyazaki T, Suyama N, Izumikawa K, Kakeya H, Yanagihara K, Mukae H, Kohno S

Internal medicine (Tokyo, Japan) 55(19) 2877-2880 2016 [Refereed]

An Autopsy Case of Lepidic Pulmonary Metastasis from Cholangiocarcinoma.

Nagayoshi Y, Yamamoto K, Hashimoto S, Hisatomi K, Doi S, Nagashima S, Kurohama H, Ito M, Takazono T, Nakamura S, Miyazaki T, Kohno S

Internal medicine (Tokyo, Japan) 55(19) 2849-2853 2016 [Refereed]

Successful Treatment of Aspergillus Empyema Using Open Window Thoracostomy Salvage Treatment and the Local Administration of an Antifungal Agent.

Ashizawa N, Nakamura S, Ide S, Tashiro M, Takazono T, Imamura Y, Miyazaki T, Izumikawa K, Yamamoto Y, Yanagihara K, Miyazaki Y, Kohno S

Internal medicine (Tokyo, Japan) 55(15) 2093-2099 2016 [Refereed]

Pulmonary Nocardiosis Caused by Nocardia concava with a Literature Review.

Hirayama T, Takazono T, Horai Y, Tashiro M, Saijo T, Kosai K, Morinaga Y, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Izumikawa K, Yanagihara K, Kawakami A, Kohno S

Internal medicine (Tokyo, Japan) 55(9) 1213-1217 2016 [Refereed]

Clinical characteristics and risk factors of enterococcal infections in Nagasaki, Japan: a retrospective study.

Kajihara T, Nakamura S, Iwanaga N, Oshima K, Takazono T, Miyazaki T, Izumikawa K, Yanagihara K, Kohno N, Kohno S

BMC infectious diseases 15 426 Oct 2015 [Refereed]

Macrolides Promote CCL2-Mediated Macrophage Recruitment and Clearance of Nasopharyngeal Pneumococcal Colonization in Mice.

Iwanaga N, Nakamura S, Oshima K, Kajihara T, Takazono T, Miyazaki T, Izumikawa K, Yanagihara K, Sugawara A, Sunazuka T, Omura S, Kohno S

The Journal of infectious diseases 212(7) 1150-1159 Oct 2015 [Refereed]

Clinical features of pulmonary cryptococcosis in non-HIV patients in Japan.

Kohno S, Kakeya H, Izumikawa K, Miyazaki T, Yamamoto Y, Yanagihara K, Mitsutake K, Miyazaki Y, Maesaki S, Yasuoka A, Tashiro T, Mine M, Uetani M, Ashizawa K

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 21(1) 23-30 Jan 2015 [Refereed]

The effect of intravenous peramivir, compared with oral oseltamivir, on the outcome of post-influenza pneumococcal pneumonia in mice.

Tanaka A, Nakamura S, Seki M, Iwanaga N, Kajihara T, Kitano M, Homma T, Kurihara S, Imamura Y, Miyazaki T, Izumikawa K, Kakeya H, Yanagihara K, Kohno S

Antiviral therapy 20(1) 11-19 2015 [Refereed]

Two cases of emphysematous urinary tract infections successfully treated with conservative management.

Higashi Y, Nakamura S, Oshima K, Iwanaga N, Hirayama T, Kajihara T, Takazono T, Miyazaki T, Izumikawa K, Yanagihara K, Tashiro T, Kohno S

The Journal of the Japanese Association for Infectious Diseases 88(6) 861-865 Nov 2014 [Refereed]

Contribution of the Slt2-regulated transcription factors to echinocandin tolerance in Candida glabrata.

Nagayoshi Y, Miyazaki T, Minematsu A, Yamauchi S, Takazono T, Nakamura S, Imamura Y, Izumikawa K, Kakeya H, Yanagihara K, Kohno S

FEMS yeast research 14(7) 1128-1131 Nov 2014 [Refereed]

Azithromycin inhibits MUC5AC induction via multidrug-resistant Acinetobacter baumannii in human airway epithelial cells.

Yamada K, Morinaga Y, Yanagihara K, Kaku N, Harada Y, Uno N, Nakamura S, Imamura Y, Hasegawa H, Miyazaki T, Izumikawa K, Kakeya H, Mikamo H, Kohno S

Pulmonary pharmacology & therapeutics 28(2) 165-170 Aug 2014 [Refereed]

A retrospective comparative study of recombinant human thrombomodulin and gabexate mesilate in sepsis-induced disseminated intravascular coagulation patients.

Takazono T, Nakamura S, Imamura Y, Yoshioka S, Miyazaki T, Izumikawa K, Sawai T, Matsuo N, Yanagihara K, Suyama N, Kohno S

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20(8) 484-488 Aug 2014 [Refereed]

Influence of antimicrobial regimen on decreased in-hospital mortality of patients with MRSA bacteremia.

Kaku N, Yanagihara K, Morinaga Y, Yamada K, Harada Y, Migiyama Y, Nagaoka K, Matsuda J, Uno N, Hasegawa H, Miyazaki T, Izumikawa K, Kakeya H, Yamamoto Y, Kohno S

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20(6) 350-355 Jun 2014 [Refereed]

Paradoxical response to disseminated non-tuberculosis mycobacteriosis treatment in a patient receiving tumor necrosis factor-α inhibitor: a case report.

Takazono T, Nakamura S, Imamura Y, Miyazaki T, Izumikawa K, Kakeya H, Yanagihara K, Kohno S

BMC infectious diseases 14 114 Feb 2014 [Refereed]

Efficacy of aerosolized liposomal amphotericin B against murine invasive pulmonary mucormycosis.

Mihara T, Kakeya H, Izumikawa K, Obata Y, Nishino T, Takazono T, Kosai K, Morinaga Y, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Yamamoto Y, Yanagihara K, Tashiro T, Kohno S

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20(2) 104-108 Feb 2014 [Refereed]

Three cases of concurrent infection with Mycobacterium tuberculosis and Cryptococcus neoformans.

Kakeya H, Izumikawa K, Yamada K, Obata Y, Nishino T, Takazono T, Kosai K, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Tashiro T, Kohno S

Internal medicine (Tokyo, Japan) 53(15) 1685-1692 2014 [Refereed]

Importance of functional assessment in the management of community-acquired and healthcare-associated pneumonia.

Kosai K, Izumikawa K, Imamura Y, Tanaka H, Tsukamoto M, Kurihara S, Takazono T, Morinaga Y, Nakamura S, Miyazaki T, Yanagihara K, Tashiro T, Kohno S

Internal medicine (Tokyo, Japan) 53(15) 1613-1620 2014 [Refereed]

Concurrent subcutaneous candidal abscesses and pulmonary cryptococcosis in a patient with diabetes mellitus and a history of corticosteroid therapy.

Kakeya H, Izumikawa K, Yamada K, Narita Y, Nishino T, Obata Y, Takazono T, Kurihara S, Kosai K, Morinaga Y, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Takenaka M, Tashiro T, Kohno S

Internal medicine (Tokyo, Japan) 53(12) 1385-1390 2014 [Refereed]

Efficacy of combination therapy with oseltamivir phosphate and azithromycin for influenza: a multicenter, open-label, randomized study.

Kakeya H, Seki M, Izumikawa K, Kosai K, Morinaga Y, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Tashiro T, Kohno S

PloS one 9(3) e91293 2014 [Refereed]

In vivo efficacy of biapenem with ME1071, a novel metallo-β-lactamase (MBL) inhibitor, in a murine model mimicking ventilator-associated pneumonia caused by MBL-producing Pseudomonas aeruginosa.

Yamada K, Yanagihara K, Kaku N, Harada Y, Migiyama Y, Nagaoka K, Morinaga Y, Nakamura S, Imamura Y, Miyazaki T, Izumikawa K, Kakeya H, Hasegawa H, Yasuoka A, Kohno S

International journal of antimicrobial agents 42(3) 238-243 Sep 2013 [Refereed]

Azithromycin attenuates lung inflammation in a mouse model of ventilator-associated pneumonia by multidrug-resistant Acinetobacter baumannii.

Yamada K, Yanagihara K, Kaku N, Harada Y, Migiyama Y, Nagaoka K, Morinaga Y, Nakamura S, Imamura Y, Miyazaki T, Izumikawa K, Kakeya H, Hasegawa H, Mikamo H, Kohno S

Antimicrobial agents and chemotherapy 57(8) 3883-3888 Aug 2013 [Refereed]

Efficacy of AiiM, an N-acylhomoserine lactonase, against Pseudomonas aeruginosa in a mouse model of acute pneumonia.

Migiyama Y, Kaneko Y, Yanagihara K, Morohoshi T, Morinaga Y, Nakamura S, Miyazaki T, Hasegawa H, Izumikawa K, Kakeya H, Kohrogi H, Kohno S

Antimicrobial agents and chemotherapy 57(8) 3653-3658 Aug 2013 [Refereed]

A case of influenza pneumonia following pneumococcal infection in an adult patient with concurrent encephalopathy with a lesion in the splenium of the corpus callosum.

Inoue Y, Hirayama T, Kondo A, Tomari S, Miyazaki T, Izumikawa K, Kakeya H, Yamamoto Y, Yanagihara K, Tashiro T, Kohno S

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 87(4) 451-456 Jul 2013 [Refereed]

Toll-like receptor 4 agonistic antibody promotes innate immunity against severe pneumonia induced by coinfection with influenza virus and Streptococcus pneumoniae.

Tanaka A, Nakamura S, Seki M, Fukudome K, Iwanaga N, Imamura Y, Miyazaki T, Izumikawa K, Kakeya H, Yanagihara K, Kohno S

Clinical and vaccine immunology : CVI 20(7) 977-985 Jul 2013 [Refereed]

In vivo efficacy of daptomycin against methicillin-resistant Staphylococcus aureus in a mouse model of hematogenous pulmonary infection.

Harada Y, Yanagihara K, Yamada K, Migiyama Y, Nagaoka K, Morinaga Y, Nakamura S, Imamura Y, Hasegawa H, Miyazaki T, Izumikawa K, Kakeya H, Kohno S

Antimicrobial agents and chemotherapy 57(6) 2841-2844 Jun 2013 [Refereed]

The heme-binding protein Dap1 links iron homeostasis to azole resistance via the P450 protein Erg11 in Candida glabrata.

Hosogaya N, Miyazaki T, Nagi M, Tanabe K, Minematsu A, Nagayoshi Y, Yamauchi S, Nakamura S, Imamura Y, Izumikawa K, Kakeya H, Yanagihara K, Miyazaki Y, Kugiyama K, Kohno S

FEMS yeast research 13(4) 411-421 Jun 2013 [Refereed]

Prospective randomized comparison study of piperacillin/tazobactam and meropenem for healthcare-associated pneumonia in Japan.

Yamamoto Y, Izumikawa K, Morinaga Y, Nakamura S, Kurihara S, Imamura Y, Miyazaki T, Tsukamoto M, Kakeya H, Yanagihara K, Yasuoka A, Kohno S

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 19(2) 291-298 Apr 2013 [Refereed]

Multilocus sequence typing of Cryptococcus neoformans in non-HIV associated cryptococcosis in Nagasaki, Japan.

Mihara T, Izumikawa K, Kakeya H, Ngamskulrungroj P, Umeyama T, Takazono T, Tashiro M, Nakamura S, Imamura Y, Miyazaki T, Ohno H, Yamamoto Y, Yanagihara K, Miyzaki Y, Kohno S

Medical mycology 51(3) 252-260 Apr 2013 [Refereed]

Dissection of Ire1 functions reveals stress response mechanisms uniquely evolved in Candida glabrata.

Miyazaki T, Nakayama H, Nagayoshi Y, Kakeya H, Kohno S

PLoS pathogens 9(1) e1003160 Jan 2013 [Refereed]

A case series of chronic necrotizing pulmonary aspergillosis and a new proposal.

Tashiro T, Izumikawa K, Tashiro M, Morinaga Y, Nakamura S, Imamura Y, Miyazaki T, Kakeya H, Yamamoto Y, Yanagihara K, Hayashi T, Nagayasu T, Kohno S

Japanese journal of infectious diseases 66(4) 312-316 2013 [Refereed]

Necrotizing pneumonia due to femoral osteomyelitis caused by community-acquired methicillin-resistant Staphylococcus aureus.

Iwanaga N, Fukuda Y, Nakamura S, Imamura Y, Miyazaki T, Izumikawa K, Kakeya H, Yanagihara K, Soda H, Tashiro T, Kohno S

Internal medicine (Tokyo, Japan) 52(13) 1531-1536 2013 [Refereed]

Bronchoalveolar lavage galactomannan for the diagnosis of chronic pulmonary aspergillosis.

Izumikawa K, Yamamoto Y, Mihara T, Takazono T, Morinaga Y, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Nishino T, Tsukamoto M, Kakeya H, Yanagihara K, Mine M, Yasuoka A, Tashiro T, Kohno S

Medical mycology 50(8) 811-817 Nov 2012 [Refereed]

Correlation between triazole treatment history and susceptibility in clinically isolated Aspergillus fumigatus.

Tashiro M, Izumikawa K, Hirano K, Ide S, Mihara T, Hosogaya N, Takazono T, Morinaga Y, Nakamura S, Kurihara S, Imamura Y, Miyazaki T, Nishino T, Tsukamoto M, Kakeya H, Yamamoto Y, Yanagihara K, Yasuoka A, Tashiro T, Kohno S

Antimicrobial agents and chemotherapy 56(9) 4870-4875 Sep 2012 [Refereed]

A case of bronchial aspergillosis caused by Aspergillus udagawae and its mycological features.

Gyotoku H, Izumikawa K, Ikeda H, Takazono T, Morinaga Y, Nakamura S, Imamura Y, Nishino T, Miyazaki T, Kakeya H, Yamamoto Y, Yanagihara K, Yasuoka A, Yaguchi T, Ohno H, Miyzaki Y, Kamei K, Kanda T, Kohno S

Medical mycology 50(6) 631-636 Aug 2012 [Refereed]

An adult case of influenza-associated encephalitis successfully treated with high dose intravenous immunoglobulins.

Iwanaga N, Nakamura S, Tanaka A, Fukuda Y, Imamura Y, Miyazaki T, Izumikawa K, Kakeya H, Yamamoto Y, Yanagihara K, Soda H, Tashiro T, Kohno S

Kansenshogaku zasshi. The Journal of the Japanese Association for Infectious Diseases 86(3) 295-299 May 2012 [Refereed]

The efficacy and safety of high-dose arbekacin sulfate therapy (once-daily treatment) in patients with MRSA infection.

Yamamoto Y, Izumikawa K, Hashiguchi K, Fukuda Y, Kobayashi T, Kondo A, Inoue Y, Morinaga Y, Nakamura S, Imamura Y, Miyazaki T, Kakeya H, Yanagihara K, Kohno S

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 18(2) 241-246 Apr 2012 [Refereed]

Antifungal susceptibilities of Aspergillus fumigatus clinical isolates obtained in Nagasaki, Japan.

Tashiro M, Izumikawa K, Minematsu A, Hirano K, Iwanaga N, Ide S, Mihara T, Hosogaya N, Takazono T, Morinaga Y, Nakamura S, Kurihara S, Imamura Y, Miyazaki T, Nishino T, Tsukamoto M, Kakeya H, Yamamoto Y, Yanagihara K, Yasuoka A, Tashiro T, Kohno S

Antimicrobial agents and chemotherapy 56(1) 584-587 Jan 2012 [Refereed]

A case of refractory chronic respiratory tract infection due to Pseudomonas aeruginosa successfully controlled by combination of clarithromycin and azithromycin.

Yamamoto Y, Izumikawa K, Hosogaya N, Morinaga Y, Nakamura S, Imamura Y, Miyazaki T, Sakamoto N, Ishimatu Y, Kakeya H, Yanagihara K, Yasuoka A, Kohno S

Internal medicine (Tokyo, Japan) 51(11) 1383-1386 2012 [Refereed]

Active surveillance of methicillin-resistant Staphylococcus aureus with the BD GeneOhm MRSA™ assay in a respiratory ward in Nagasaki, Japan.

Izumikawa K, Yamamoto Y, Yanagihara K, Kiya T, Matsuda J, Morinaga Y, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Nishino T, Tsukamoto M, Kakeya H, Yasuoka A, Tashiro T, Kamihira S, Kohno S

Japanese journal of infectious diseases 65(1) 33-36 2012 [Refereed]

Functional characterization of the regulators of calcineurin in Candida glabrata.

Miyazaki T, Izumikawa K, Nagayoshi Y, Saijo T, Yamauchi S, Morinaga Y, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Kohno S

FEMS yeast research 11(8) 621-630 Dec 2011 [Refereed]

The glycosylphosphatidylinositol-linked aspartyl protease Yps1 is transcriptionally regulated by the calcineurin-Crz1 and Slt2 MAPK pathways in Candida glabrata.

Miyazaki T, Izumikawa K, Yamauchi S, Inamine T, Nagayoshi Y, Saijo T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Yasuoka A, Kohno S

FEMS yeast research 11(5) 449-456 Aug 2011 [Refereed]

Diagnostic significance of Aspergillus species isolated from respiratory samples in an adult pneumology ward.

Tashiro T, Izumikawa K, Tashiro M, Takazono T, Morinaga Y, Yamamoto K, Imamura Y, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Yasuoka A, Kohno S

Medical mycology 49(6) 581-587 Aug 2011 [Refereed]

Synergistic antifungal effect of lactoferrin with azole antifungals against Candida albicans and a proposal for a new treatment method for invasive candidiasis.

Kobayashi T, Kakeya H, Miyazaki T, Izumikawa K, Yanagihara K, Ohno H, Yamamoto Y, Tashiro T, Kohno S

Japanese journal of infectious diseases 64(4) 292-296 2011 [Refereed]

Evaluation of the Cica Fungi Test Candida, a novel serum Candida mannan antigen kit, and its comparison with Cand-Tec in candidemia patients.

Takazono T, Izumikawa K, Nagayoshi Y, Tanaka A, Mihara T, Kosai K, Saijo T, Imamura Y, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Kamihira S, Kohno S

Japanese journal of infectious diseases 64(2) 116-120 2011 [Refereed]

Role of the Slt2 mitogen-activated protein kinase pathway in cell wall integrity and virulence in Candida glabrata.

Miyazaki T, Inamine T, Yamauchi S, Nagayoshi Y, Saijo T, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Kohno S

FEMS yeast research 10(3) 343-352 May 2010 [Refereed]

Roles of calcineurin and Crz1 in antifungal susceptibility and virulence of Candida glabrata.

Miyazaki T, Yamauchi S, Inamine T, Nagayoshi Y, Saijo T, Izumikawa K, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Kohno S

Antimicrobial agents and chemotherapy 54(4) 1639-1643 Apr 2010 [Refereed]

Skn7p is involved in oxidative stress response and virulence of Candida glabrata.

Saijo T, Miyazaki T, Izumikawa K, Mihara T, Takazono T, Kosai K, Imamura Y, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Kohno S

Mycopathologia 169(2) 81-90 Feb 2010 [Refereed]

A case of intravascular large B-cell lymphoma (IVLBCL) with no abnormal findings on chest computed tomography diagnosed by random transbronchial lung biopsy.

Kaku N, Seki M, Doi S, Hayashi T, Imanishi D, Imamura Y, Kurihara S, Miyazaki T, Izumikawa K, Kakeya H, Yamamoto Y, Yanagihara K, Tashiro T, Kohno S

Internal medicine (Tokyo, Japan) 49(24) 2697-2701 2010 [Refereed]

Diffuse alveolar hemorrhage following itraconazole injection.

Izumikawa K, Nakano K, Kurihara S, Imamura Y, Yamamoto K, Miyazaki T, Sakamoto N, Seki M, Ishimatsu Y, Kakeya H, Yamamoto Y, Yanagihara K, Tsuchiya T, Yamasaki N, Tagawa T, Mukae H, Nagayasu T, Kohno S

Internal medicine (Tokyo, Japan) 49(5) 497-500 2010 [Refereed]

Efficacy of combination antifungal therapy with intraperitoneally administered micafungin and aerosolized liposomal amphotericin B against murine invasive pulmonary aspergillosis.

Takazono T, Izumikawa K, Mihara T, Kosai K, Saijo T, Imamura Y, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Kohno S

Antimicrobial agents and chemotherapy 53(8) 3508-3510 Aug 2009 [Refereed]

A case of pulmonary cryptococcosis followed by pleuritis in an apparently immunocompetent patient during fluconazole treatment.

Izumikawa K, Zhao Y, Motoshima K, Takazono T, Saijo T, Kurihara S, Nakamura S, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Hayashi T, Kohno S

Medical mycology 46(6) 595-599 Sep 2008 [Refereed]

A case of Legionella pneumophila pneumonia followed by invasive aspergillosis.

Saijo T, Izumikawa K, Takazono T, Kosai K, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Seki M, Kakeya H, Yamamoto Y, Yanagihara K, Miyazaki Y, Fukushima K, Kohno S

Japanese journal of infectious diseases 61(5) 379-381 Sep 2008 [Refereed]

The bZip transcription factor Cgap1p is involved in multidrug resistance and required for activation of multidrug transporter gene CgFLR1 in Candida glabrata.

Chen KH, Miyazaki T, Tsai HF, Bennett JE

Gene 386(1-2) 63-72 Jan 2007 [Refereed]

Kre29p is a novel nuclear protein involved in DNA repair and mitotic fidelity in Candida glabrata.

Miyazaki T, Tsai HF, Bennett JE

Current genetics 50(1) 11-22 Jul 2006 [Refereed]

Fluconazole treatment is effective against a Candida albicans erg3/erg3 mutant in vivo despite in vitro resistance.

Miyazaki T, Miyazaki Y, Izumikawa K, Kakeya H, Miyakoshi S, Bennett JE, Kohno S

Antimicrobial agents and chemotherapy 50(2) 580-586 Feb 2006 [Refereed]

Environmental isolation of Cryptococcus neoformans from an endemic region of HIV-associated cryptococcosis in Thailand.

Kuroki M, Phichaichumpon C, Yasuoka A, Chiranairadul P, Chosa T, Sirinirund P, Miyazaki T, Kakeya H, Higashiyama Y, Miyazaki Y, Ishida Y, Kohno S

Yeast (Chichester, England) 21(10) 809-812 Jul 2004 [Refereed]

Misc

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Current recommendations and importance of antifungal stewardship for the management of invasive candidiasis.

Miyazaki T, Kohno S

Expert review of anti-infective therapy 13(9) 1171-1183 2015 [Refereed][Invited]

Elucidation of multiantifungal resistance mechanisms in pathogenic fungi and their clinical impacts.

Miyazaki T

The Japanese journal of antibiotics 67(4) 263-271 Aug 2014 [Refereed][Invited]

Clinical features, risk factors and treatment of fulminant Mycoplasma pneumoniae pneumonia: a review of the Japanese literature.

Izumikawa K, Izumikawa K, Takazono T, Kosai K, Morinaga Y, Nakamura S, Kurihara S, Imamura Y, Miyazaki T, Tsukamoto M, Yanagihara K, Hara K, Kohno S

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20(3) 181-185 Mar 2014 [Refereed]

Pathogenesis and clinical features of chronic pulmonary aspergillosis - is it possible to distinguish CNPA and CCPA clinically?

Izumikawa K, Tashiro T, Tashiro M, Takazono T, Kosai K, Morinaga Y, Kurihara S, Nakamura S, Imamura Y, Miyazaki T, Tsukamoto M, Kakeya H, Hayashi T, Yanagihara K, Nagayasu T, Kohno S

Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy 20(3) 208-212 Mar 2014 [Refereed]

ER stress response mechanisms in the pathogenic yeast Candida glabrata and their roles in virulence.

Miyazaki T, Kohno S

Virulence 5(2) 365-370 Feb 2014 [Refereed][Invited]

Association Memberships

THE JAPANESE SOCIETY OF INTERNAL MEDICINE(1573) , THE JAPANESE RESPIRATORY SOCIETY(233) , THE JAPANESE ASSOCIATION FOR INFECTIOUS DISEASES(347) , JAPANESE SOCIETY OF CHEMOTHERAPY(180) , THE JAPANESE SOCIETY FOR MEDICAL MYCOLOGY(51) , THE JAPANESE SOCIETY FOR TUBERCULOSIS(64) , THE JAPANESE SOCIETY FOR CLINICAL MICROBIOLOGY(64) , THE JAPAN SOCIETY OF DRUG DELIVERY SYSTEM(123) , THE JAPANESE SOCIETY FOR AIDS RESEARCH(104) , THE JAPAN SOCIETY FOR RESPIRATORY ENDOSCOPY(111)