HIROHARA Shiho

J-GLOBAL         Last updated: Jun 27, 2018 at 03:31
 
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Name
HIROHARA Shiho
Affiliation
Ube National College of Technology
Section
Department of Chemical and Biological Engineering

Research Areas

 
 

Published Papers

 
A. Fadlan, H. Tanimoto, T. Ito, Y. Aritomi, M. Ueno, M. Tokuda, S. Hirohara, M. Obata, T. Morimoto, K. Kakiuchi
Bioorg. Med. Chem.   26(8) 1848-1858   May 2018   [Refereed]
Photosensitized Protein-damaging Activity, Cytotoxicity, and Antitumor Effects of P(V)porphyrins Using Long-wavelength Visible-light through Electron Transfer
Hirakawa, Kazutaka; Ouyang, Dongyan; Ibuki, Yuko; Hirohara, Shiho; Okazaki, Shigetoshi; Kono, Eiji; Kanayama, Naohiro; Nakazaki, Jotaro; Segawa, Hiroshi
Chemical Research in Toxicology      2018   [Refereed]
M. Obata, R. Otobuchi, T. Kuroyanagi, M. Takahashi, S. Hirohara
J. Polym. Sci. Part A: Polym. Chem.   55 395-403   Oct 2017   [Refereed]
Y. Kusumastuti, Y. Shibasaki, S. Hirohara, M. Kobayashi, K. Terada,T. Ando, M. Tanihara
J Tissue Eng Regen Med   11(3) 869-876   Jan 2015   [Refereed]
M. Obata, S. Tanaka, H. Mizukoshi, E. Ishihara, M. Takahashi, S. Hirohara
J. Polym. Sci. Part A: Polym. Chem.   55 3395-3403   Feb 2017   [Refereed]
M. Obata, S. Hirohara
J. Photochem. Photobiol. B: Biol.   162 324-331   Sep 2016   [Refereed]
Effects of intermediate research presentation on the graduation study
N. Mitome, K. Shimabukuro, S. Hirohara, M. Negoro, H. Yamasaki
Proceeding of International Symposium on Advances in Technology Education (ISATE)   536-539   2016   [Refereed]
Effect of polymer matrix on the performance of pressure-sensitive paint comprising 5,10,15,20-tetrakis(pentafluorophenyl)porphinato platinum(II) and poly(1,1,1,3,3,3-hexafluoroisopropyl-co-tert-butyl methacrylates)
M. Obata, R. Asato, S. Hirohara, K. Mituso
J. Appl. Polym. Sci.   https://doi.org/10.1002/app.43    Oct 2015   [Refereed]
S. Hirohara, C. Oka, M. Totani, M. Obata, J. Yuasa, H. Ito, M. Tamura, H. Matsui, K. Kakiuchi, T. Kawai, M. Kawaichi, M. Tanihara
J. Med. Chem.   58 8658-8670   Nov 2015   [Refereed]
Development of sugar-linked porphyrin for photochemical cancer medicine
HIROHARA Shiho
The 37th Anual Meeting of The Japanese Society for Photomedicine and Photobiology   44-45   2015
M.Obata, R.Asato, K. Mitsuo, S. Hirohara
J. Polym. Sci. Part A: Polym. Chem.   52 963-972   Dec 2013   [Refereed]
Hybrid polyion complex gel of succinylated poly (prohypgly) and chitosan and its feasibility study as threedimensional scaffold
Y. Kusumastuti, Y. Shibasaki, S. Hirohara, M. Kobayashi, K. Terada, T. Ando, M. Tanihara
Jounal of Tissue Engineering and Regenerative medicine,   8 (SI) 355-356   2014   [Refereed]
M. Tamura, H. Matsui, S. Hirohara, K. Kakiuchi, M. Tanihara, N. Takahashi, K. Nakai, Y. Kanai, H. Watabe, J. Hatazawa
Bioorg. Med. Chem.   22 2563-2570   Apr 2014   [Refereed]
M. Tamura, H. Matsui, S. Hirohara, K. Kakiuchi, M. Tanihara, N. Takahashi, K. Nakai, Y. Kanai, H. Watabe, J. Hatazawa
Chem. Lett.   43(6) 778-780   Feb 2014   [Refereed]
Synthesis and PDT Effect of Polysaccharide-conjugated Porphyrins
S. Hirohara, K. Sharyo, M. Obata, H. Akahoshi, M. Shiraishi, K. Fujitsu, N. Akiyama, K. Sugimoto, Y. Nakano, M. Tamura, H. Matsui and M. Tanihara
ALA-Porphyrin Science   3(1) 11-21   Jul 2014   [Refereed]
Synthesis of Fluoroporphyrin comprising Glucose and Ethylene Glycol and Evaluation of Its Photodynamic Effect
S. Hirohara, M. Shiraishi, N. Akiyama, M. Obata, M. Tamura, H. Ito, H. Matui, K. Kakiuchi
ALA-Porphyrin Science   3(2) 61-69   Dec 2014   [Refereed]
Synthesis of Hydroxyethyloxy-conjugated Porphyrin Derivatives and Evaluation of Their Photodynamic Effect
K. Fujitake, T. Tomiyama, S. Fujiyama, M. Obata, M. Tamura, H. Matsui, S. Hirohara
ALA-Porphyrin Science   2(1) 47-56   Nov 2013   [Refereed]
S. Hirohara, K. Sharyo, Y. Kawasaki, M. Totani, A. Tomotsuka, R. Funasako, N. Yasui, Y. Hasegawa, J. Yuasa, T. Nakashima, T. Kawai, C. Oka, M. Kawaichi, M. Obata, M. Tanihara
Bull. Chem. Soc. Jpn.   86(11) 1295-1308   2013   [Refereed]
A. Kusumaatmaja, T. Ando, K. Terada, S. Hirohara, T. Nakashima, T. Kawai, T. Terashima, M. Tanihara
J. Polym. Sci. Part A: Polym. Chem.   51(12) 2527-2535   Mar 2013   [Refereed]
Angiogenesis and cell infiltration induced by enzymatically synthesized amylose hydrogels impregnated with bFGF
M. Tanihara, Y. Shibasaki, J. Takahara, M. Sunako, S. Hirohara, K. Terada, T. Ando
Jounal of Tissue Engineering and Regenerative medicine,   6 (SI) 295   2012   [Refereed]
S. Hirohara, Y. Kawasaki, R. Funasako, N. Yasui, M. Totani, H. Alitomo, J. Yuasa, T. Kawai, C. Oka, M. Kawaichi, M. Obata, M. Tanihara
Bioconjugate Chem.   23(9) 1881-1890   Sep 2012   [Refereed]
M. Obata, T. Kobari, S. Hirohara, M. Tanihara
J. Polym. Sci. Part A: Polym. Chem.   53(21) 4672-4677   2012   [Refereed]
M. Obata, E. Ohtake, S. Hirohara, M. Tanihara, S. Yano
J. Polym. Sci. Part A: Polym. Chem.   50(17) 3592-3597   Feb 2012   [Refereed]
M. Obata, M. Shimizu, T. Ohta, A. Matsushige, K. Iwai, S. Hirohara, M. Tanihara
Polym. Chem.   2(3) 651-658   Sep 2011   [Refereed]
S. Yano, S. Hirohara, M. Obata, Y. Hagiya , S. Ogura, A. Ikeda, H. Kataoka, M. Tanaka, T. Joh
J. Photochem. Photobiol. C: Photochem. Rev.   12(1) 46-67   2011   [Refereed]
Y. Shibasaki, S. Hirohara, K. Terada, T. Ando, M. Tanihara
Biopolymer (Peptide Scienece)   96(3) 302-315   Oct 2011   [Refereed]
J. Takahara, K. Hosoya, M. Sunako, S. Hirohara, K. Terada, T. Ando, M. Tanihara
Acta Biomaterialia   6(8) 3138-3145   Aug 2010   [Refereed]
S. Hirohara, M. Nishida, K. Sharyo, M. Obata, T. Ando, M. Tanihara
Bioorg. Med. Chem.   18(4) 1526-1535   2010   [Refereed]
M. Obata, N. Matsuura, K. Mitsuo, H. Nagai, K. Asai, M. Harada, S. Hirohara, M. Tanihara, S. Yano
J. Polym. Sci. Part A: Polym. Chem.   48(3) 663-670   2010   [Refereed]
S. Hirohara, M. Obata, H. Alitomo, K. Sharyo, T. Ando, M. Tanihara, S. Yano
J. Photochem. Photobiol. B: Biol.   97(1) 22-33   2009
M. Obata, M. Harada, H. Ohi, S. Hirohara, M. Gottchaldt, S. Yano
Chem. Pharm. Bull.   57(10) 1107-1109   Sep 2009   [Refereed]
M. Obata, S. Hirohara, R. Tanaka, I. Kinoshita, K. Ohkubo, S. Fukuzumi, M. Tanihara, S. Yano
J. Med. Chem.   52(9) 2747-2753   May 2009   [Refereed]
S. Hirohara, M. Obata, H. Alitomo, K. Sharyo, T. Ando, S. Yano, M. Tanihara
Bioconjugate Chem.   20(5) 944-952   2009   [Refereed]
Synthesis and photocytotoxicity of mono-, di-, tri- and tetra- substituted glucosyl-porphyrin platinum(II) complexes for PDT drugs
K. Sharyo, S. Hirohara, M. Obata, T. Ando, M. Tanihara
J. Biol. Inorg. Chem.   14 S161   2009
Synthesis and PDT effect of glucosylated porphyrin metal complexes”, J. Biol. Inorg. Chem.
S. Hirohara, M. Nishida, K. Sharyo, M. Obata, T. Ando, M. Tanihara
J. Biol. Inorg. Chem.   14 S162   2009
Cell Adhesion and Migration on Synthetic Polypeptide, Poly(Pro-Hyp-Gly), Grafting Fibronectin-derived GRGDS and PHSRN Peptides
Y. Shibasaki, K. Terada, S. Hirohara, T. Ando, M. Tanihara
Int. J. Artif. Organs.   32 456   2009   [Refereed]
S. Hirohara, M. Obata, H. Alitomo, K. Sharyo, T. Ando, S. Yano, M. Tanihara
Biol. Pharm. Bull.   3 2265-2272   2008   [Refereed]
Novel Peptides Having BFGF-like Activities and Their Application to Scaffolds for Tissue Regeneration
M. Tanihara, S. Hirohara, T. Ando, Y. Suzuki, Y. Suzuki
Int. J. Artif. Organs   31(7) 610   2008
M. Obata, S. Hirohara, K. Sharyo, H. Alitomo, S. Ogata, K. Kajiwara, M. Tanihara, C. Ohtsuki, S. Yano
Biochem. Biophys. Acta   1770(8) 1204-1211   Aug 2007   [Refereed]
M. Obata, M. Morita, K. Nakase, K. Mitsuo, K. Asai, S. Hirohara, S. Yano
J. Polym. Sci. Part A: Polym. Chem.   45(14) 2876-2885   Aug 2007
S. Hirohara, M. Obata, S. Ogata, K. Kajiwara, C. Ohtsuki, M. Tanihara, S. Yano
J. Photochem. Photobiol. B: Biol.   84 56-63   2006   [Refereed]
M. Obata, Y. Tanaka, N. Araki, S. Hirohara, S. Yano, K. Mituo, K. Asai, M. Harada, T. Kakuchi, C. Ohtsuki
J. Polym. Sci. Part A: Polym. Chem.   43(14) 2997-3006   Jun 2005   [Refereed]
S. Hirohara, M. Obata, A. Saito, S. Ogata, C. Ohtsuki, S. Higashida, S. Ogura, I. Okura, Y. Sugai, Y. Mikata, M. Tanihara, S. Yano
J. Photochem. Photobiol. B: Biol.   78(1) 7-15   Jan 2005   [Refereed]
Log P Values of Glycoconjugated Porphyrins for Photodynamic Therapy Evaluated by Reverse-Phase HPLC
S. Hirohara, M. Obata, S. Ogura, I. Okura, S. Higashida, C. Ohtsuki, S. Ogata, Y. Nishikawa, M. Takenaka, H. Ono, Y. Mikata, S. Yano
J. Porphyrins Phthalocyanines   8 1289-1292   Jun 2004   [Refereed]
S. Hirohara, M. Obata, A. Saito, S. Ogata, C. Ohtsuki, S. Higashida, S. Ogura, I. Okura, Y. Sugai, Y. Mikata, M. Tanihara, S. Yano
Photochem. Photobiol.   80(2) 301-308   Sep 2004   [Refereed]
A. Hamazawa, I. Kinoshita, B. Breedlove, K. Isobe, M. Shibata, T. Kakuchi, S. Hirohara, M. Obata, Y. Mikata, S. Yano
Chem. Lett.   (3) 388-389   2002   [Refereed]
Y. Arima, S. Akimoto, T. Yamazaki, M. Shibata, S. Hirohara, S. Yano, T. Kakuchi, I. Yamazaki
Chem. Phys. Lett.   361(1/2) 152-158   Jul 2002   [Refereed]
Development of sugar-linked bacteriochlorin derivatives for photodynamic therapy
S. Hirohara, Y. Onchi, Y. Sugai, Y. Mikata, I. Okura, S. Ogura, Isamu, T. Kakuchi, S. Yano
J. Inorg. Biochem.   86 263   2001
Y. Mikata, Y. Shinohara, K. Yoneda, Y. Nakamura, K. Esaki, M. Tanahashi, I. Brudzinska, S. Hirohara, M. Yokoyama, K. Mogami, T. Tanase, K. Takashiba, K. Nabeshima, R. Takagi, M. Takatani, T. Okamoto, I. Kinoshita, M. Doe, A. Hamazawa, M. Morita, F. Nishida, T. Sakakibara, C. Orvig, S. Yano
J. Org. Chem.   66(11) 3783-3789   Jun 2001   [Refereed]

Books etc

 
Spectroscopic Tools for the Diagnosis and Treatment of Cancer; Pacifichem Symposium, Chapter (10)
S. Hirohara, Y. Kubota, N. Akiyama, M. Obata, H. Matsui, K. Kakiuchi (Part:Joint Work, Synthesis and Photocytotoxicity of Fluorophenylporphyrin Derivatives having Two Different Functional Groups)
Sankeisha Co Ltd.   Aug 2017   
Spectroscopic Tools for the Diagnosis and Treatment of Cancer; Pacifichem Symposium, Chapter (8)
M. Obata, Y. Tsutsui, S. Hirohara (Part:Joint Work, Synthesis and Characterization of Water-soluble Polymers Bearing Porphyrin Moieties at Initiating End for Photodynamic Therapy)
Sankeisha Co Ltd.   Aug 2017   

Conference Activities & Talks

 
Synthesis and Photodynamic Activity of S-Glucosylated Porphyrins
Arif Fadlan, Hiroki Tanimoto, Shiho Hirohara, Kiyomi Kakiuchi
TEAC2017   12 Sep 2017   
Development of S-Glucose Conjugated Porphyrins for PDT Drug Photosensitizer
Arif Fadlan・Shiho Hirohara・Hiroki Tanimoto・Kiyomi Kakiuchi
16 Apr 2017   
My idea as a teacher of UNCT ~ Devices to balance education and research ~ [Invited]
HIROHARA Shiho
16 Mar 2017   
Creation of new cancer medical (theranostics) [Invited]
HIROHARA Shiho
25 Feb 2017   
Creation of aranostics drug using porphyrin [Invited]
HIROHARA Shiho
21 Jan 2017   
Photocytotoxicity of fluorochlorin with two substituents [Invited]
HIROHARA Shiho
25 Jun 2016   
Evaluation of physical properties of chlorin having two substituents
HIROHARA Shiho
23 Apr 2016   

Association Memberships