KITATANI Kazuyuki

J-GLOBAL         Last updated: Mar 25, 2019 at 16:47
 
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Name
KITATANI Kazuyuki
URL
http://db.tohoku.ac.jp/whois/e_detail/5156cd9fe2d5f274358122fb0a6a8c81.html
Affiliation
Setsunan University
Section
Tohoku Medical Megabank OrganizationDepartment of Community Medical Supports
Job title
Assistant Professor

Research Areas

 
 

Academic & Professional Experience

 
Apr 2018
 - 
Today
Associate Professor, Faculty of Pharmaceutical Sciences, Setsunan University
 
Apr 2017
 - 
Mar 2018
Senior Assistant Professor, Graduate School of Medicine, Tohoku University
 
Apr 2012
 - 
Mar 2017
Assistant Professor, Tohoku Medical Megabank Organization, Tohoku University
 
Dec 2008
 - 
Mar 2012
Assistant Professor, Department of Clinical Laboratory/Hematology, Tottori University Hospital
 
Jul 2007
 - 
Nov 2008
Instructor (Faculty Appointment), Department of Biochemistry and Molecular Biology, Medical University of South Carolina
 
Oct 2002
 - 
Jun 2007
Post doctral fellow, Dr. Yusuf A. Hannun Laboratory, Department of Biochemistry and Molecular Biology, Medical University of South Carolina
 
2007
 - 
2007
Visiting Scientis, Cincinnati Children’s Hospital, Division of Human Genetics
 

Awards & Honors

 
2016
Outstanding Contribution in Reviewing, European Journal of Surgical Oncology
 
Apr 2012
Young Investigator Award, Gaucher Generation Program
 
Nov 2006
Travel Award, 41th Annual Southeaster Regional Lipid Conference
 
Nov 2004
Postdoctral Award, 39th Annual Southeaster Regional Lipid Conference
 

Published Papers

 
La-Related Protein 4 as a Suppressor for Motility of Ovarian Cancer Cells.
Egiz M., Usui T., Ishibashi M, Zhang X, Toyoshima M, Shigeta S, Usui T, Kitatani K, Yaegashi N.
247 59-67   Jan 2019   [Refereed]
Zhang X, Kitatani K, Toyoshima M, Ishibashi M, Usui T, Minato J, Egiz M, Shigeta S, Fox T, Deering T, Kester M, Yaegashi N.
Molecular Cancer Therapeutics   17(1) 50-59   2018   [Refereed]
Hasegawa-Minato J, Toyoshima M, Ishibashi M, Zhang X, Shigeta S, Grandori C, Kitatani K, Yaegashi N.
Oncotarget   9(3) 3483-3496   2018   [Refereed]
M Wada, D Canals, M Adada, N Coant, M F Salama, K L Helke, J S Arthur, K R Shroyer, K Kitatani, L M Obeid, Y A Hannun
Oncogene      Nov 2017   [Refereed]
Kitatani K, Usui T, Sriraman S.K, Toyoshima M, Ishibashi M, Shigeta S, Nagase S, Sakamoto M, Ogiso H, Okazaki T, Hannun Y.A, Torchilin V.P, Yaegashi N.
Oncogene   35(21) 2801-2812   2016   [Refereed]
Mizuno S, Ogishima S, Kitatani K, Kikuchi M, Tanaka H, Yaegashi N, Nakaya J.
PLoS ONE   11(2)    2016   [Refereed]
Shigeta S, Toyoshima M, Kitatani K, Ishibashi M, Usui T, Yaegashi N.
Oncogene   35(27) 3577-3586   2016   [Refereed]
Kitatani K, Wada M, Perry D, Usui T, Sun Y, Obeid L.M, Yaegashi N, Grabowski G.A, Hannun Y.A.
PLoS ONE   10(8)    2015   [Refereed]
Yazama H, Kitatani K, Fujiwara K, Kato M, Hashimoto-Nishimura M, Kawamoto K, Hasegawa K, Kitano H, Bielawska A, Bielawski J, Okazaki T.
International Journal of Clinical Oncology   20(3) 438-446   2015   [Refereed]
Mashiko S, Kitatani K, Toyoshima M, Ichimura A, Dan T, Usui T, Ishibashi M, Shigeta S, Nagase S, Miyata T, Yaegashi N.
Cancer Biology and Therapy   16(2) 253-260   2015   [Refereed]
Kitatani K, Taniguchi M, Okazaki T.
Molecules and Cells   38(6) 482-495   2015   [Refereed]
Perry D.M, Newcomb B, Adada M, Wu B.X, Roddy P, Kitatani K, Siskind L, Obeid L.M, Hannun Y.A.
Journal of Biological Chemistry   289(32) 22401-22412   2014   [Refereed]
Tsounapi P, Saito M, Kitatani K, Dimitriadis F, Ohmasa F, Shimizu S, Kinoshita Y, Takenaka A, Satoh K.
European Journal of Pharmacology   691(1-3) 182-189   2012   [Refereed]
Perry D.M, Kitatani K, Roddy P, El-Osta M, Hannun Y.A.
Journal of Lipid Research   53(8) 1513-1521   2012   [Refereed]
Ohmasa F, Saito M, Oiwa H, Tsounapi P, Shomori K, Kitatani K, Dimitriadis F, Kinoshita Y, Satoh K.
BJU International   110(6B)    2012   [Refereed]
Taniguchi M, Kitatani K, Kondo T, Hashimoto-Nishimura M, Asano S, Hayashi A, Mitsutake S, Igarashi Y, Umehara H, Takeya H, Kigawa J, Okazaki T.
Journal of Biological Chemistry   287(47) 39898-39910   2012   [Refereed]
Asano S, Kitatani K, Taniguchi M, Hashimoto M, Zama K, Mitsutake S, Igarashi Y, Takeya H, Kigawa J, Hayashi A, Umehara H, Okazaki T.
Molecular and Cellular Biology   32(16) 3242-3252   2012   [Refereed]
Tsounapi P, Saito M, Dimitriadis F, Kitatani K, Kinoshita Y, Shomori K, Takenaka A, Satoh K.
Life Sciences   90(17-18) 649-656   2012   [Refereed]
Fujiwara K, Kitatani K, Fukushima K, Yazama H, Umehara H, Kikuchi M, Igarashi Y, Kitano H, Okazaki T.
International Journal of Clinical Oncology   16(2) 133-140   2011   [Refereed]
Sun Y, Ran H, Liou B, Quinn B, Zamzow M, Zhang W, Bielawski J, Kitatani K, Setchell K.D.R, Hannun Y.A, Grabowski G.A.
PLoS ONE   6(4)    2011   [Refereed]
El-Shewy H.M, Abdel-Samie S.A, al Qalam A.M, Lee M.-H, Kitatani K, Anelli V, Jaffa A.A, Obeid L.M, Luttrell L.M.
Molecular Endocrinology   25(12) 2144-2156   2011   [Refereed]
Jenkins R.W, Clarke C.J, Canals D, Snider A.J, Gault C.R, Heffernan-Stroud L, Wu B.X, Simbari F, Roddy P, Kitatani K, Obeid L.M, Hannun Y.A.
Journal of Biological Chemistry   286(15) 13292-13303   2011   [Refereed]
Lafont E, Kitatani K, Okazaki T, S{é}gui B.
Recent Patents on Anti-Cancer Drug Discovery   6(3) 324-333   2011   [Refereed]
Mullen T.D, Spassieva S, Jenkins R.W, Kitatani K, Bielawski J, Hannun Y.A, Obeid L.M.
Journal of Lipid Research   52(1) 68-77   2011   [Refereed]
Shakor A.B.A, Taniguchi M, Kitatani K, Hashimoto M, Asano S, Hayashi A, Nomura K, Bielawski J, Bielawska A, Watanabe K, Kobayashi T, Igarashi Y, Umehara H, Takeya H, Okazaki T.
Journal of Biological Chemistry   286(41) 36053-36062   2011   [Refereed]
Kitatani K, Asano S, Hashimoto M, Taniguchi M, Okazaki T.
Seikagaku   83(6) 495-505   2011   [Refereed]
Sun Y, Liou B, Ran H, Skelton M.R, Williams M.T, Vorhees C.V, Kitatani K, Hannun Y.A, Witte D.P, Xu Y.-H, Grabowski G.A.
Human Molecular Genetics   19(6) 1088-1097   2010   [Refereed]
Jenkins R.W, Canals D, Idkowiak-Baldys J, Simbari F, Roddy P, Perry D.M, Kitatani K, Luberto C, Hannun Y.A.
Journal of Biological Chemistry   285(46) 35706-35718   2010   [Refereed]
Kitatani K, Luberto C.
Advances in experimental medicine and biology   688 276-285   2010   [Refereed]
Kitatani K, Sheldon K, Anelli V, Jenkins R.W, Sun Y, Grabowski G.A, Obeid L.M, Hannun Y.A.
Journal of Biological Chemistry   284(19) 12979-12988   2009   [Refereed]
Kitatani K, Sheldon K, Rajagopalan V, Anelli V, Jenkins R.W, Sun Y, Grabowski G.A, Obeid L.M, Hannun Y.A.
Journal of Biological Chemistry   284(19) 12972-12978   2009   [Refereed]
Sun Y, Ran H, Zamzow M, Kitatani K, Skelton M.R, Williams M.T, Vorhees C.V, Witte D.P, Hannun Y.A, Grabowski G.A.
Human Molecular Genetics   19(4) 634-647   2009   [Refereed]
Sundaram K, Mani S.K, Kitatani K, Wu K, Pestell R.G, Reddy S.V.
Journal of Cellular Biochemistry   103(6) 1747-1759   2008   [Refereed]
The sphingolipid salvage pathway in ceramide metabolism and signaling.
Kitatani K., Idkowiak-Baldys J., Hannun Y.A.
Cell. Signal.   20 1010-1018   2008   [Invited]
Idkowiak-Baldys J, Becker K.P, Kitatani K, Hannun Y.A.
Journal of Biological Chemistry   281(31) 22321-22331   2006   [Refereed]
Taha T.A, Kitatani K, El-Alwani M, Bielawski J, Hannun Y.A, Obeid L.M.
FASEB Journal   20(3) 482-484   2006   [Refereed]
Kitatani K, Idkowiak-Baldys J, Bielawski J, Taha T.A, Jenkins R.W, Senkal C.E, Ogretmen B, Obeid L.M, Hannun Y.A.
Journal of Biological Chemistry   281(48) 36793-36802   2006   [Refereed]
Becker K.P, Kitatani K, Idkowiak-Baldys J, Bielawski J, Hannun Y.A.
Journal of Biological Chemistry   280(4) 2606-2612   2005   [Refereed]
Pettus B.J, Kitatani K, Chalfant C.E, Taha T.A, Kawamori T, Bielawski J, Obeid L.M, Hannun Y.A.
Molecular Pharmacology   68(2) 330-335   2005   [Refereed]
Taha T.A, Kitatani K, Bielawski J, Cho W, Hannun Y.A, Obeid L.M.
Journal of Biological Chemistry   280(17) 17196-17202   2005   [Refereed]
Kitatani K, Akiba S, Hayama M, Sato T.
Archives of Biochemistry and Biophysics   395(2) 208-214   2001   [Refereed]
Kitatani K, Oka T, Murata T, Hayama M, Akiba S, Sato T.
Archives of Biochemistry and Biophysics   382(2) 296-302   2000   [Refereed]
Akiba S, Murata T, Kitatani K, Sato T.
Biological and Pharmaceutical Bulletin   23(11) 1293-1297   2000   [Refereed]
Kitatani K, Akiba S, Sato T.
Biological and Pharmaceutical Bulletin   23(12) 1430-1433   2000   [Refereed]

Misc

 
Kitatani K, Iwabuchi K, Snider A, Riboni L.
Mediators of Inflammation   2016    2016   [Invited]
酒粕に含まれるスフィンゴ脂質の検出・半定量的評価とその由来の解析
平田みよ,浦野義崇,稲葉繁樹,北谷和之,岡崎俊朗,北垣浩志
J. Brew. Soc. Japan   106 848-853   2012   [Refereed]
C型慢性肝炎の治療薬開発を通してみた国内外の臨床試験検索サイトの活用方法の模索
牧江俊雄,黒田祥平,中村剛,今井優樹,森永紀,北谷和之
医薬品医療機器レギュラトリーサイエンス   43 446-451   2012   [Refereed]
スフィンゴ脂質を利用した機能性リポソーム
北谷和之
生物工学会誌   88 678-678   2010   [Invited]
Regulation of ceramide by sphingomyelin synthase
北谷和之,橋本真由美,杉本優子,谷口真,岡崎俊朗
Cells   41 8-11   2009   [Invited]
セラミドと悪性腫瘍
北谷和之,岡崎俊朗
The Lipids   20 289-290   2009   [Invited]
セラミドを中心としたスフィンゴ脂質代謝
北谷和之,浅野智志,橋本真由美,谷口真、岡崎俊朗
生化学   83 495-505   2011   [Invited]
Kitatani K, Cowart L.A, Hannun Y.A.
Sphingolipid Biology   153-165   2006   [Refereed][Invited]

Books etc

 
Generation of signaling molecules by de novo sphingolipid synthesis
Kitatani K., Cowart L. A., and Hannun Y. A. (Part:Joint Work, Sphingolipid Biology)
Springer   2006   
セラミドの細胞内機能概論:スフィンゴミエリン合成酵素ファミリー
北谷和之,岡崎俊朗 (Part:Joint Work, セラミド-基礎と応用)
2011   

Conference Activities & Talks

 
Ceramide synthase 2-ceramide axis limits metastatic potential of ovarian cancer
KITATANI Kazuyuki
2 May 2017   
Ceramide limits phosphatidylinositol-3-kinase-controlled cell motility in ovarian cancer: potential of ceramide as a tumor metastasis suppressor
Kitatani K, Usui T, Sriraman SK, Ogiso H, Toyoshima M, Ishibashi M, Shigeta S, Nagase S, Okazaki T, Hannun YA, Torchilin, VP, Yaegashi N
iCC/SLC   6 May 2015   
Ceramide limits phosphatidylinositol­3-kinase C2β-controlled cell motility in ovarian cancer: potential of ceramide liposomes as antimetastatic reagents.
KITATANI Kazuyuki
29 Mar 2015   
Identification of Ceramide as an Inhibitory Lipid for Phosphatidylinositol-3-Kinase-Controlled Cell Motility in Ovarian Cancer: Potential of Ceramide as an Antimetastatic Reagent
MasafumiToyoshima、ShravanK.Sriraman、MasumiIshibashi、ShogoShigeta、SatsukiMashiko、SatoruNagase、MasahiroSakamoto、VladimirP.Torchilin、YusufA.Hannun、NobuoYaegashi
7th International Ceramide Conference   20 Oct 2013   
セラミドによる細胞移動性の調節:卵巣がん転移をおさえる創薬に向けて
豊島将文、増子さつき、重田昌吾、石橋ますみ、八重樫伸生
第8回スフィンゴテラピィ研究会   12 Jul 2013   
卵巣がん転移を標的にした創薬:スフィンゴ脂質の利用
豊島将文、増子さつき、重田昌吾、石橋ますみ、八重樫伸生
第12回日本婦人科分子標的研究会   5 Jul 2013   
セラミドによる細胞移動運動の調節
豊島将文、増子さつき、重田昌吾、石橋ますみ、八重樫伸生
第55回日本脂質生化学会   6 Jun 2013   

Research Grants & Projects

 
Roles for ceramide in ovarian cancer
JSPS: kakenhi
Project Year: Apr 2016 - Mar 2019    Investigator(s): KITATANI Kazuyuki
Identification of acid β-glucosidase as a tumor suppressor gene
Mizutani Foundation for Glycoscience: 
Project Year: Apr 2017 - Sep 2018    Investigator(s): KITATANI Kazuyuki
Cancer biology of ceramide synthases and establishment of cancer therapeutics
Takeda Science Foundation: 
Project Year: Apr 2017 - Mar 2018    Investigator(s): KITATANI Kazuyuki
Ceramide-based therapy for ovarian cancer metastasis
JSPS: kakenhi
Project Year: Apr 2014 - Mar 2015    Investigator(s): KITATANI Kazuyuki
p38δ is a novel target for anti-inflammation therapy of Gaucher's disease.
Gaucher Generation Grant: New Investigator Award
Project Year: Apr 2012 - Mar 2015    Investigator(s): Kazuyuki Kitatani
Regulation of inflammation by sphingolipid salvage
Grant-in-Aid for Scientific Research
Project Year: Apr 2011 - Mar 2012    Investigator(s): Kazuyuki Kitatani
Role of ceramide in molecular cell biology
The Sumitomo Foundation: 
Project Year: Apr 2010 - Mar 2011    Investigator(s): KITATANI Kazuyuki
Regulation of sphingolipid signal by acid-beta-glucosidase
JSPS: kakenhi
Project Year: Apr 2009 - Mar 2010    Investigator(s): KITATANI Kazuyuki

Social Contribution

 
Multidisciplinary Approach Forum MAF 2014
[Presenter, Planner]  20 Sep 2014 - 21 Sep 2014