論文

査読有り
2020年1月24日

Comparison of Clinical Characteristics of Stent Thrombosis Between the Right Coronary Artery and the Left Coronary Artery - A Subanalysis of the REAL-ST Registry.

Circulation journal : official journal of the Japanese Circulation Society
  • Yusuke Watanabe
  • ,
  • Kenichi Sakakura
  • ,
  • Hideo Fujita
  • ,
  • Masanobu Ohya
  • ,
  • Kazunori Horie
  • ,
  • Futoshi Yamanaka
  • ,
  • Gaku Nakazawa
  • ,
  • Hiromasa Otake
  • ,
  • Hiroki Shiomi
  • ,
  • Masahiro Natsuaki
  • ,
  • Kenji Ando
  • ,
  • Kazushige Kadota
  • ,
  • Shigeru Saito
  • ,
  • Takeshi Kimura
  • ,
  • Shoichi Kuramitsu

84
2
開始ページ
169
終了ページ
177
記述言語
英語
掲載種別
DOI
10.1253/circj.CJ-19-0885

BACKGROUND: Stent thrombosis (ST) remains a severe complication following stent implantation. We previously reported the risk factors for ST after 2nd-generation drug-eluting stent (DES) in the REAL-ST (Retrospective Multicenter Registry of ST After First- and Second-Generation DES Implantation) registry.Methods and Results:In this subanalysis, we aimed to reveal the difference in ST between right coronary (RCA) and left (LCA) coronary arteries. A total of 307 patients with ST were divided into the RCA-ST group (n=93) and the LCA-ST group (n=214). Multivariate analysis revealed younger age (odds ratio [OR] 0.96, 95% confidence interval [CI] 0.93-0.99, P=0.01), ostial lesion at the time of index percutaneous coronary intervention (OR 4.37, 95% CI 1.43-13.33, P=0.01), bifurcation lesion at the time of index PCI (OR 0.05, 95% CI 0.02-0.12, P<0.01), chronic total occlusion (CTO) lesion at the time of index PCI indication (OR 4.19, 95% CI 1.05-16.71, P=0.04), and use of prasugrel at the time of ST (OR 7.30, 95% CI 1.44-36.97, P=0.02) were significantly associated with RCA-ST. CONCLUSIONS: Younger age, ostial or CTO lesion, and use of prasugrel at the time of ST were prominent factors in RCA-ST, whereas bifurcation lesion was associated with LCA-ST. We should pay attention to the differences between RCA-ST and LCA-ST to prevent ST.

リンク情報
DOI
https://doi.org/10.1253/circj.CJ-19-0885
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/31902802

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