論文

査読有り 国際誌
2020年9月

OPtical frequency domain imaging vs. INtravascular ultrasound in percutaneous coronary InterventiON in patients with Acute Coronary Syndrome: Study protocol for a randomized controlled trial.

Journal of cardiology
  • Hiromasa Otake
  • ,
  • Takashi Kubo
  • ,
  • Toshiro Shinke
  • ,
  • Kiyoshi Hibi
  • ,
  • Shigemitsu Tanaka
  • ,
  • Masaru Ishida
  • ,
  • Toru Kataoka
  • ,
  • Tomofumi Takaya
  • ,
  • Masamichi Iwasaki
  • ,
  • Shinjo Sonoda
  • ,
  • Tetsuya Ioji
  • ,
  • Takashi Akasaka

76
3
開始ページ
317
終了ページ
321
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.jjcc.2020.03.010

BACKGROUND: A recent clinical trial demonstrated that optical frequency domain imaging (OFDI) guidance in percutaneous coronary intervention (PCI) is noninferior to intravascular ultrasound (IVUS) guidance in patients with coronary artery disease with regard to target vessel failure (composed of cardiac death, myocardial infarction attributed to the target vessel, and clinically-driven target vessel revascularization) at 12 months. The impact of OFDI guidance in PCI for patients with acute coronary syndrome (ACS) remains uncertain. METHODS: OPINION ACS is a multicenter, prospective, randomized, controlled, open-label, parallel group, non-inferiority trial in Japan. Eligible patients will be randomly assigned to receive either OFDI- or IVUS-guided PCI. PCI is performed using the sirolimus-eluting stent in accordance with certain OFDI and IVUS criteria for optimal stent deployment. All patients will undergo follow-up angiography and OFDI imaging at 8 months. The primary endpoint is the minimum lumen area, as measured by OFDI at 8 months. CONCLUSION: The OPINION ACS trial outcomes will provide insights regarding the impact of OFDI-guided PCI on in-stent restenosis at 8 months in patients with ACS.

リンク情報
DOI
https://doi.org/10.1016/j.jjcc.2020.03.010
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/32340781

エクスポート
BibTeX RIS