論文

国際誌
2021年4月

Feasibility of morphological assessment of coronary artery calcification with electrocardiography-gated non-contrast computed tomography: a comparative study with optical coherence tomography.

The international journal of cardiovascular imaging
  • Yu Takahashi
  • ,
  • Takayoshi Toba
  • ,
  • Hiromasa Otake
  • ,
  • Yusuke Fukuyama
  • ,
  • Shinsuke Nakano
  • ,
  • Yoichiro Matsuoka
  • ,
  • Kosuke Tanimura
  • ,
  • Yu Izawa
  • ,
  • Hiroyuki Kawamori
  • ,
  • Atsushi K Kono
  • ,
  • Sei Fujiwara
  • ,
  • Ken-Ichi Hirata

37
4
開始ページ
1445
終了ページ
1453
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1007/s10554-020-02093-z

To investigate the feasibility of pre-procedural morphological assessment of coronary artery calcification in severely calcified lesions with electrocardiography (ECG)-gated non-contrast computed tomography (CT). Severely calcified coronary arteries in patients who underwent ECG-gated non-contrast CT prior to optical coherence tomography (OCT)-guided percutaneous coronary intervention (PCI) were studied retrospectively. CT and OCT data were co-registered by marking landmark structures such as side branches and reviewed side by side with cross-sectional images. The maximum calcium angle (MCA) and presence of nodular calcification (NC) were evaluated. A total of 496 cross-sections in 16 lesions were included in this analysis. The Pearson correlation coefficient between CT- and OCT-derived MCA was 0.92 (p < 0.001). Bland-Altman plots of OCT-derived MCA in relation to CT-derived MCA showed a mean bias of 4.8 degrees with 95% limits of agreement of - 69.7 to 79.4 degrees. Sensitivity, specificity, and positive and negative predictive values of CT in identifying MCA > 270 degrees were 90.3%, 79.7%, 92.1%, and 97.4%, respectively. Sensitivity, specificity, and positive and negative predictive values of CT in identifying NC were 73.3%, 97.5%, 47.8%, and 99.2%, respectively. ECG-gated non-contrast coronary CT might be helpful to obtain detailed information of severe coronary artery calcification before PCI.

リンク情報
DOI
https://doi.org/10.1007/s10554-020-02093-z
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/33151511
ID情報
  • DOI : 10.1007/s10554-020-02093-z
  • PubMed ID : 33151511

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