2020年
G-quadruplex-proximity protein labeling based on peroxidase activity
Chemical Communications
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- 巻
- 56
- 号
- 78
- 開始ページ
- 11641
- 終了ページ
- 11644
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.1039/d0cc02571b
Peroxidase-proximity protein labeling was performed using a hemin-parallel G-quadruplex (G4) complex. A tyrosine labeling reaction using an N-methyl luminol derivative was accelerated in close proximity to the hemin with enhanced peroxidase activity by binding to parallel G4. The TERRA-hemin complex activated the labeling of many RNA-binding proteins, including heterogeneous nuclear ribonucleoproteins, in a HeLa cell lysate.
- リンク情報
- ID情報
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- DOI : 10.1039/d0cc02571b
- ORCIDのPut Code : 86875428
- PubMed ID : 33000777
- SCOPUS ID : 85092538681