MISC

1997年7月

Effects of ketamine and pentobarbitone on acetylcholine release from the rat frontal cortex in vivo

BRITISH JOURNAL OF ANAESTHESIA
  • T Kikuchi
  • ,
  • Y Wang
  • ,
  • H Shinbori
  • ,
  • K Sato
  • ,
  • F Okumura

79
1
開始ページ
128
終了ページ
130
記述言語
英語
掲載種別
出版者・発行元
PROF SCI PUBL

We have studied the effects of ketamine and pentobarbitone on acetylcholine (ACh) release from the rat frontal cortex using microdialysis. Ketamine 25, 50 and 100 mg kg(-1) increased ACh release from the frontal cortex to 286%, 253% and 381% of basal release, respectively. In contrast, pentobarbitone 10, 20 and 40 mg kg(-1) caused 73%, 78% and 96% inhibition of basal levels, respectively. The results suggest that ketamine and pentobarbitone have opposite effects on ACh release from the rat frontal cortex, as seen previously in the rat hippocampus.

リンク情報
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/9301402
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:A1997XM54600024&DestApp=WOS_CPL
URL
http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030748228&origin=inward
ID情報
  • ISSN : 0007-0912
  • PubMed ID : 9301402
  • SCOPUS ID : 0030748228
  • Web of Science ID : WOS:A1997XM54600024

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