1997年7月
Effects of ketamine and pentobarbitone on acetylcholine release from the rat frontal cortex in vivo
BRITISH JOURNAL OF ANAESTHESIA
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- 巻
- 79
- 号
- 1
- 開始ページ
- 128
- 終了ページ
- 130
- 記述言語
- 英語
- 掲載種別
- 出版者・発行元
- PROF SCI PUBL
We have studied the effects of ketamine and pentobarbitone on acetylcholine (ACh) release from the rat frontal cortex using microdialysis. Ketamine 25, 50 and 100 mg kg(-1) increased ACh release from the frontal cortex to 286%, 253% and 381% of basal release, respectively. In contrast, pentobarbitone 10, 20 and 40 mg kg(-1) caused 73%, 78% and 96% inhibition of basal levels, respectively. The results suggest that ketamine and pentobarbitone have opposite effects on ACh release from the rat frontal cortex, as seen previously in the rat hippocampus.
- リンク情報
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- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/9301402
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:A1997XM54600024&DestApp=WOS_CPL
- URL
- http://www.scopus.com/inward/record.url?partnerID=HzOxMe3b&scp=0030748228&origin=inward
- ID情報
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- ISSN : 0007-0912
- PubMed ID : 9301402
- SCOPUS ID : 0030748228
- Web of Science ID : WOS:A1997XM54600024