Maeshima Kazuhiro

J-GLOBAL         Last updated: Jan 6, 2020 at 12:12
Maeshima Kazuhiro
Alternative names
Research Organization of Information and Systems
National Institute of Genetics
Job title
Ph.D.(Osaka University)
Other affiliation

Research Areas


Academic & Professional Experience

Apr 2009
Professor, Department of Genetics, School of Life Science, SOKENDAI
Apr 2009
Professor, Department of Chromosome Science, National Institute of Genetics
Apr 1996
Mar 1999
JSPS Fellow DC1, Osaka University

Awards & Honors

May 2016
2015 Kihara Memorial Foundation Academic Award, Kihara Memorial Foundation

Published Papers

Babokhov M, Hibino K, Itoh Y, Maeshima K
Journal of molecular biology      Nov 2019   [Refereed]
Ashwin SS, Nozaki T, Maeshima K, Sasai M
Proceedings of the National Academy of Sciences of the United States of America      Sep 2019   [Refereed]
Prieto EI, Maeshima K
Essays in biochemistry   63(1) 133-145   Apr 2019   [Refereed]
Maeshima K, Ide S, Babokhov M
Current opinion in cell biology   58 95-104   Mar 2019   [Refereed]
Nagashima R, Hibino K, Ashwin SS, Babokhov M, Fujishiro S, Imai R, Nozaki T, Tamura S, Tani T, Kimura H, Shribak M, Kanemaki MT, Sasai M, Maeshima K
The Journal of cell biology      Mar 2019   [Refereed]
Maeshima K, Hibino K, Hudson DF
The Journal of cell biology      Apr 2018   [Refereed]
Maeshima K, Matsuda T, Shindo Y, Imamura H, Tamura S, Imai R, Kawakami S, Nagashima R, Soga T, Noji H, Oka K, Nagai T
Current biology : CB   28(3) 444-451.e6   Jan 2018   [Refereed]
Maeshima K, Tamura S, Shimamoto Y
Biophysics and physicobiology   15 189-195   2018   [Refereed]
Hansen JC, Connolly M, McDonald CJ, Pan A, Pryamkova A, Ray K, Seidel E, Tamura S, Rogge R, Maeshima K
Biochemical Society transactions   46(1) 67-76   Dec 2017   [Refereed]
Imai R, Nozaki T, Tani T, Kaizu K, Hibino K, Ide S, Tamura S, Takahashi K, Shribak M, Maeshima K
Molecular biology of the cell   28(23) 3349-3359   Aug 2017   [Refereed]
Nozaki T, Imai R, Tanbo M, Nagashima R, Tamura S, Tani T, Joti Y, Tomita M, Hibino K, Kanemaki MT, Wendt KS, Okada Y, Nagai T, Maeshima K
Molecular cell   67(2) 282-293.e7   Jul 2017   [Refereed]
Shimamoto Y, Tamura S, Masumoto H, Maeshima K
Molecular biology of the cell   28(11) 1580-1589   Apr 2017   [Refereed]
Shinkai S, Nozaki T, Maeshima K, Togashi Y
Nucleus (Austin, Tex.)   8(4) 353-359   Apr 2017   [Refereed]
Shinkai S, Nozaki T, Maeshima K, Togashi Y
PLoS computational biology   12(10) e1005136   Oct 2016   [Refereed]
Kawamoto Y, Sasaki A, Chandran A, Hashiya K, Ide S, Bando T, Maeshima K, Sugiyama H
Journal of the American Chemical Society      Oct 2016   [Refereed]
Chen C, Lim HH, Shi J, Tamura S, Maeshima K, Surana U, Gan L
Molecular biology of the cell   27(21) 3357-3368   Sep 2016   [Refereed]
Sasaki A, Ide S, Kawamoto Y, Bando T, Murata Y, Shimura M, Yamada K, Hirata A, Nokihara K, Hirata T, Sugiyama H, Maeshima K
Scientific reports   6 29261   Jul 2016   [Refereed]
Imai R, Komeda S, Shimura M, Tamura S, Matsuyama S, Nishimura K, Rogge R, Matsunaga A, Hiratani I, Takata H, Uemura M, Iida Y, Yoshikawa Y, Hansen JC, Yamauchi K, Kanemaki MT, Maeshima K
Scientific reports   6 24712   Apr 2016   [Refereed]
Maeshima K, Rogge R, Tamura S, Joti Y, Hikima T, Szerlong H, Krause C, Herman J, Seidel E, DeLuca J, Ishikawa T, Hansen JC
The EMBO journal      Apr 2016   [Refereed]
Maeshima K, Ide S, Hibino K, Sasai M
Current Opinion in Genetics and Development.   37 36-45   Jan 2016   [Refereed][Invited]
Eukaryotic chromatin is a negatively charged long polymer composed of genomic DNA, histones, and various proteins. The charged property causes the chromatin structure to be dynamically changed. These dynamic changes are critical for genome functio...


Nuclear integrity maintenance by lamin and chromatin
Yuta Shimamoto, Kazuhiro Maeshima
Igakunoayumi   272 20541-20545   Jan 2020   [Invited]
Sato Kana Hibino Kayo Maeshima Kazuhiro
academist Journal.      May 2019   [Invited]
Maeshima Kazuhiro Matuda Tomoki Nagai Takeharu
Journal of Japanese society for Magnesium Research   37 13-18   2019   [Invited]
Shimamoto Yuta, Tamura Sachiko, Maeshima Kazuhiro
58(1) 24-26   Jan 2018   [Refereed][Invited]
日比野佳代, 前島一博
実験医学   35(19) 3211‐3217   Dec 2017
日比野佳代, 前島一博
JSI Newsl   24(2) 24   Apr 2016
永島 峻甫, 野崎 慎, 今井 亮輔, 田村 佐知子, 堀江 恭二, 前島 一博
日本細胞生物学会大会講演要旨集   67回 173-173   Jun 2015
Isotope News   (719) 2-6   Mar 2014

Books etc

How small numbers of long genomic DNA are stored in cells
Maeshima Kazuhiro (Part:Contributor, Chapter 8)
Springer, Singapore   2018   
Combination approach of live-cell imaging and computational modeling toward further comprehensive understanding genome, chromatin and epigenetics
Hibino, K., Kaizu, K., Takahashi, K., Maeshima, K. (Part:Contributor, Chapter 11)
Academic   2017   
Dynamic chromatin folding in the cell
Nozaki, T., Hudson, F. D., Tamura, S., Maeshima, K. (Part:Contributor, Chapter 4)
Academic Press   2017   ISBN:ISBN-10: 0128034807

Conference Activities & Talks

Chromosome organization in living cells revealed by single nucleosome imaging [Invited]
Kazuhiro Maeshima
42th Molecular Biology Society of Japan Annual Meeting   3 Dec 2019   
Chromatin dynamics and transcription [Invited]
Kazuhiro Maeshima
57th Biophysical Society of Japan Annual Meeting,   24 Sep 2019   Biophysical Society of Japan
Mitotic chromosome condensation process revealed by single nucleosome imaging in living human cells.
Kazuhiro Maeshima
EMBO Workshop on Organization of bacterial and eukaryotic genomes by SMC complexes   10 Sep 2019   
Chromosome organization in living human cells revealed by single nucleosome imaging. [Invited]
Kazuhiro Maeshima
oint 12th EBSA-10th ICBP-IUPAP Biophysics Congress   21 Jul 2019   
Chromosome organization in living human cells revealed by single nucleosome imaging. [Invited]
Kazuhiro Maeshima
Francois Jacob Conference   7 Jun 2019   

Research Grants & Projects

Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(挑戦的萌芽研究)
Project Year: 2010 - 2012    Investigator(s): Kazuhiro MAESHIMA
To label a certain genomic region in the cell, a harsh condition to denature DNA is required. In this proposal, we tried to target a fluorescently tagged DNA sequence to the genomic DNA using some homologous recombination proteins. However, with h...
Ministry of Education, Culture, Sports, Science and Technology: Grants-in-Aid for Scientific Research(若手研究(B))
Project Year: 2007 - 2008    Investigator(s): Kazuhiro MAESHIMA