大西彰 (Akira ONISHI) - マイポータル

基本情報

研究者番号: 30414890
J-GLOBAL ID: 201401038748080568
researchmap会員ID: 7000007801

研究分野

ライフサイエンス / 動物生命科学 /

論文

Development of human hepatocellular carcinoma in X-linked severe combined immunodeficient pigs: An orthotopic xenograft model

Kohei Mishima 1, Osamu Itano 1 2, Sachiko Matsuda 1, Shunichi Suzuki 3, Akira Onishi 3 4, Masashi Tamura 5, Masanori Inoue 5, Yuta Abe 1, Hiroshi Yagi 1, Taizo Hibi 6 …

PLos One 16(3) e0248352 2021年3月22日査読有り責任著者
Pathological findings after third- and second-generation everolimus-eluting stent implantations in coronary arteries from autopsy cases and an atherosclerotic porcine model

Suguru Migita 1 2, Daisuke Kitano 2, Yuxin Li 3, Yutaka Koyama 1 2, Sayaka Shimodai-Yamada 1, Akira Onishi 4, Daiichiro Fuchimoto 5, Shunichi Suzuki 5, Yoshiyuki Nakamura 6, Taka-Aki Matsuyama 7 …

Sci.Rep 11(1) 6281 2021年3月18日査読有り責任著者
Organogenesis of Ileal Peyer's Patches Is Initiated Prenatally and Accelerated Postnatally With Comprehensive Proliferation of B Cells in Pigs

Mutsumi Furukawa 1, Shun Ito 1, Shunichi Suzuki 2, Daiichiro Fuchimoto 2, Akira Onishi 3, Kanae Niimi 1, Katsuki Usami 1, Guoyao Wu 4, Fuller W Bazer 4, Kouetsu Ogasawara 5 …

Front Immunol 11 604674 2020年12月4日査読有り責任著者
Effect of pemafibrate (K-877), a novel selective peroxisome proliferator-activated receptor α modular (SPPARMα), in atherosclerosis model using low density lipoprotein receptor knock-out swine with balloon injury

Hirokazu Konishi 1, Katsumi Miyauchi 1, Akira Onishi 2, Shunichi Suzuki 3, Daiichiro Fuchimoto 3, Jun Shitara 1, Hirohisa Endo 1, Hideki Wada 1, Shinichiro Doi 1, Ryo Naito 1 …

PLos One 15(11) e0241195 2020年11月17日査読有り責任著者
Elucidation of the Effects of a Current X-SCID Therapy on Intestinal Lymphoid Organogenesis Using an In Vivo Animal Model.

Nochi T, Suzuki S, Ito S, Morita S, Furukawa M, Fuchimoto D, Sasahara Y, Usami K, Niimi K, Itano O …

Cell Mol Gastroenterol Hepatol. 10(1) 83-100 2020年2月1日査読有り
Magnetically Promoted Rapid Immunofluorescence Staining for Frozen Tissue Sections.

Onishi T, Matsuda S, Nakamura Y, Kuramoto J, Tsuruma A, Sakamoto S, Suzuki S, Fuchimoto D, Onishi A, Chikaki S …

J Histochem Cytochem. 67(8) 575-587 2019年8月査読有り
Establishment of a model of sentinel lymph node metastasis using immunodeficient swine.

Kurihara T, Matsuda S, Nakamura Y, Suzuki S, Fuchimoto D, Onishi A, Saeki K, Nakagawa T, Fujiwara R, Kamata M …

Sci Rep. 28;9(1) 7923-7923 2019年5月査読有り
Establishment of a strain of haemophilia-A pigs by xenografting of foetal testicular tissue from neonatally moribund cloned pigs.

Kaneko H1, Kikuchi K2, 3, Nakai M2, 4, Fuchimoto D5, Suzuki S6, Sembon S2, 4, Noguchi J2 …

Sci Rep 7(1) 17026-17026 2017年12月5日査読有り
教育に向けたマウス体外受精

大西彰、三角浩司

日本大学生物資源科学部教職課程紀要 (1) 65-70 2017年9月30日査読有り筆頭著者
Lack of calcium oscillation causes failure of oocyte activation after intracytoplasmic sperm injection in pigs.

Nakai M, Ito J, Suzuki SI, Fuchimoto DI, Senbon S, Suzuki M, Noguchi J, Kaneko H, Onishi A, Kashiwazaki N …

J Reprod Dev. 62(6) 615-621 2016年12月査読有り
Generation and characterization of RAG2 knockout pigs as animal model for severe combined immunodeficiency.

Suzuki S, Iwamoto M, Hashimoto M, Suzuki M, Nakai M, Fuchimoto D, Sembon S, Eguchi-Ogawa T, Uenishi H, Onishi A.

Vet Immunol Immunopathol. 178 37-49 2016年10月査読有り
Somatic cell reprogramming-free generation of genetically modified pigs.

Tanihara F, Takemoto T, Kitagawa E, Rao S, Do LT, Onishi A, Yamashita Y, Kosugi C, Suzuki H, Sembon S …

Sci Adv. 2(9:e1600803) 2016年9月査読有り
Efficient pig ICSI using Percoll-selected spermatozoa; evidence for the essential role of phospholipase C-ζ in ICSI success.

Nakai M, Suzuki SI, Ito J, Fuchimoto DI, Sembon S, Noguchi J, Onishi A, Kashiwazaki N, Kikuchi K.

J Reprod Dev. 62(6) 639-643 2016年9月査読有り
Development of Accelerated Coronary Atherosclerosis Model Using Low Density Lipoprotein Receptor Knock-Out Swine with Balloon Injury.

Ogita M, Miyauchi K, Onishi A, Tsuboi S, Wada H, Konishi H, Naito R, Dohi T, Kasai T, Kojima Y …

PLoS One 11(9:e0163055.) 2016年9月査読有り
Production of Piglets Using Sperm Retrieved from Host Mice Harboring Fetal Testicular Tissue of F8 Gene- Targeted Hemophilia A Pigs

Hiroyuki Kaneko, Kazuhiro Kikuchi, Michiko Nakai, Daiichiro Fuchimoto, Shunichi Suzuki, Shoichiro Sembon, Junko Noguchi, Akira Onishi

49th Annual Meeting of the Society for the Study of Reproduction, 2016年9月査読有り
Development of Human-Like Advanced Coronary Plaques in Low-Density Lipoprotein Receptor Knockout Pigs and Justification for Statin Treatment Before Formation of Atherosclerotic Plaques.

Li Y, Fuchimoto D, Sudo M, Haruta H, Lin QF, Takayama T, Morita S, Nochi T, Suzuki S, Sembon S …

J Am Heart Assoc. 18(5(4):e002779) 2016年4月査読有り責任著者
Conserved and divergent expression patterns of markers of axial development in eutherian mammals

Yoshida M, Kajikawa E, Kurokawa D, Tokunaga T, Ohnishi A, Yonemura S, Kobayashi K, Kiyonari H, Aizawa S

Developmental Dynamics 245(1) 67-86 2016年査読有り
Treatment with protein kinase C activator is effective for improvement of male pronucleus formation and further embryonic development of sperm-injected oocytes in pigs

Nakai M, Ito J, Kashiwazaki N, Men N.T, Tanihara F, Noguchi J, Kaneko H, Onishi A, Kikuchi K

Theriogenology 85(4) 703-708 2016年査読有り
Functional difference between membrane-bound and soluble human thrombomodulin

Miwa Y, Yazaki S, Iwamoto M, Suzuki S, Iwasaki K, Haneda M, Yamamoto K, Maruyama S, Onishi A, Kobayashi T

Transplantation 99(4) 702-709 2015年査読有り
Is early statin treatment justified before formation of atherosclerotic plaques?

II.Li Y, Onishi A, Sudo M, Haruta H, Lin Q-F, Takayama T, Suzuki S, Fuchimoto D, Sembon S, Iwamoto M …

Circulation 132 A13244 2015年査読有り

もっとみる

MISC

免疫不全ブタ

大西彰

腎と透析 79(6) 923-928 2015年12月筆頭著者
遺伝子改変ブタの開発

大西彰

LABIO 21 58 27-30 2014年10月筆頭著者

主要な書籍等出版物

ゲノム編集食品農林水産分野への応用と持続的社会の実現

(担当:分担執筆, 範囲:ゲノム編集によるブタの遺伝子改変) (原著:大西彰)

株式会社エヌ・ティー・エス 2021年2月26日

もっとみる