論文

査読有り
2016年3月

Prognostic value of 2-[(18) F]fluoro-2-deoxy-D-glucose positron emission tomography for patients with oral squamous cell carcinoma treated with retrograde superselective intra-arterial chemotherapy and daily concurrent radiotherapy

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY
  • Mai Shimizu
  • ,
  • Kenji Mitsudo
  • ,
  • Izumi Koike
  • ,
  • Masataka Taguri
  • ,
  • Toshinori Iwai
  • ,
  • Toshiyuki Koizumi
  • ,
  • Senri Oguri
  • ,
  • Mitomu Kioi
  • ,
  • Makoto Hirota
  • ,
  • Tomio Inoue
  • ,
  • Iwai Tohnai

121
3
開始ページ
239
終了ページ
247
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1016/j.oooo.2015.10.018
出版者・発行元
ELSEVIER SCIENCE INC

Objective. To investigate whether 2-[(18) F] fluoro-2-deoxy-D-glucose (FDG) uptake of primary tumor in oral squamous cell carcinoma (OSCC) could predict prognosis.
Study Design. Sixty-nine patients with OSCC who underwent retrograde superselective intra-arterial chemoradiotherapy were recruited and underwent dual-time-point FDG positron emission tomography twice, before treatment and 4 weeks after treatment. FDG uptake was defined as the standardized uptake value (SUVmax). The retention index (RI) and the percent change in SUV (% change SUV), derived from the dual-time-point scan, were calculated.
Results. On univariate analysis, patients with high pre-SUV, RI, and percent change SUV values had significantly worse overall survival and disease-free survival compared with patients with low values. On multivariate analysis, high pre-RI (>= 20.6%) and high percent change SUV (>= 60.0%) (delayed-image) were associated with significantly worse overall survival. High pre-SUV (>= 9.6) (delayed-image) and high pre-RI (>= 20.6%) were associated with significantly shorter disease-free survival.
Conclusions. Dual-time-point FDG positron emission tomography in OSCC provided prognostic information and predicted patient outcome.

Web of Science ® 被引用回数 : 6

リンク情報
DOI
https://doi.org/10.1016/j.oooo.2015.10.018
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000369710800011&DestApp=WOS_CPL

エクスポート
BibTeX RIS