Hirotsugu Imaeda

Profile Information

Affiliation: Special Contract Assistant Professors, Undergraduate School of Medicine Faculty of Medicine, Shiga University of Medical Science

Degree: 医学博士(滋賀医科大学)

Researcher number: 20623317
J-GLOBAL ID: 201401066195545536
researchmap Member ID: 7000007890

炎症性腸疾患
腸内細菌
粘膜免疫
生物学的製剤
薬物動態力学
医療面接
医学教育学

Research Interests

Research Areas

Research History

Apr, 2016 - Present

Assistant Professor, Division of Gastroenterology, Department of Medicine, Shiga University of Medical Science
Oct, 2015 - Mar, 2016

Special Contract Assistant Professor, Department of Clinical Education, Shiga University of Medical Science
Apr, 2014 - Sep, 2015

Special Cntract Assistant Professor, Division of Gastroenterology, Shiga University of Medical Science
Feb, 2014 - Mar, 2014

Medical Doctor, Division of Gastroenterology, Department of Medicine, Shiga University of Medical Science
Apr, 2013 - Dec, 2013

Research Fellow, Pathological unit, Massachusetts General Hospital
Jul, 2011 - Mar, 2013

Special Contract Assistant Professor, Division of Gastroenterology, Department of Medicine, Shiga University of Medical Science

Education

Papers

Efficacy and safety of single fecal microbiota transplantation for Japanese patients with mild to moderately active ulcerative colitis

Atsushi Nishida, Hirotsugu Imaeda, Masashi Ohno, Osamu Inatomi, Shigeki Bamba, Mitsushige Sugimoto, Akira Andoh

JOURNAL OF GASTROENTEROLOGY, 52(4) 476-482, Apr, 2017 Peer-reviewed
The effect of CYP3A5 genetic polymorphisms on adverse events in patients with ulcerative colitis treated with tacrolimus.

Ayumi Asada, Shigeki Bamba, Yukihiro Morita, Kenichiro Takahashi, Hirotsugu Imaeda, Atsushi Nishida, Osamu Inatomi, Mitsushige Sugimoto, Masaya Sasaki, Akira Andoh

Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver, 49(1) 24-28, Jan, 2017 Peer-reviewed
Association between serum adalimumab concentrations and endoscopic disease activity in patients with Crohn's disease

Yukihiro Morita, Hirotsugu Imaeda, Atsushi Nishida, Osamu Inatomi, Shigeki Bamba, Masaya Sasaki, Tomoyuki Tsujikawa, Mitsushige Sugimoto, Akira Andoh

JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY, 31(11) 1831-1836, Nov, 2016 Peer-reviewed
Prognostic factors affecting early colectomy in patients with moderate to severe ulcerative colitis treated with calcineurin inhibitors

Hiromitsu Ban, Shigeki Bamba, Atsushi Nishida, Osamu Inatomi, Makoto Shioya, Ken-Ichiro Takahashi, Hirotsugu Imaeda, Masaki Murata, Masaya Sasaki, Tomoyuki Tsujikawa …

EXPERIMENTAL AND THERAPEUTIC MEDICINE, 12(2) 829-834, Aug, 2016 Peer-reviewed
Enterococcus durans TN-3 Induces Regulatory T Cells and Suppresses the Development of Dextran Sulfate Sodium (DSS)-Induced Experimental Colitis

Toshihiro Kanda, Atsushi Nishida, Masashi Ohno, Hirotsugu Imaeda, Takashi Shimada, Osamu Inatomi, Shigeki Bamba, Mitsushige Sugimoto, Akira Andoh

PLOS ONE, 11(7) e0159705, Jul, 2016 Peer-reviewed
Comparison of the gut microbial community between obese and lean peoples using 16S gene sequencing in a Japanese population

Akira Andoh, Atsushi Nishida, Kenichiro Takahashi, Osamu Inatomi, Hirotsugu Imaeda, Shigeki Bamba, Katsuyuki Kito, Mitsushige Sugimoto, Toshio Kobayashi

JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION, 59(1) 65-70, Jul, 2016 Peer-reviewed
Eotaxin-3 (CCL26) Expression in Human Pancreatic Myofibroblasts

Takehide Fujimoto, Hirotsugu Imaeda, Kenichiro Takahashi, Atsushi Nishida, Makoto Shioya, Osamu Inatomi, Shigeki Bamba, Hisanori Shiomi, Masaji Tani, Akira Andoh

PANCREAS, 45(3) 420-424, Mar, 2016 Peer-reviewed
Increased Expression of Interleukin-36, a Member of the Interleukin-1 Cytokine Family, in Inflammatory Bowel Disease

Atsushi Nishida, Kentaro Hidaka, Toshihiro Kanda, Hirotsugu Imaeda, Makoto Shioya, Osamu Inatomi, Shigeki Bamba, Katsuyuki Kitoh, Mitsushige Sugimoto, Akira Andoh

INFLAMMATORY BOWEL DISEASES, 22(2) 303-314, Feb, 2016 Peer-reviewed
Prediction of clinical and endoscopic responses to anti-tumor necrosis factor-α antibodies in ulcerative colitis.

Morita Y, Bamba S, Takahashi K, Imaeda H, Nishida A, Inatomi O, Sasaki M, Tsujikawa T, Sugimoto M, Andoh A

Scandinavian journal of gastroenterology, 51(8) 1-8, Feb, 2016 Peer-reviewed
NUDT15 R139C-related thiopurine leukocytopenia is mediated by 6-thioguanine nucleotide-independent mechanism in Japanese patients with inflammatory bowel disease

Ayumi Asada, Atsushi Nishida, Makoto Shioya, Hirotsugu Imaeda, Osamu Inatomi, Shigeki Bamba, Katsuyuki Kito, Mitsushige Sugimoto, Akira Andoh

JOURNAL OF GASTROENTEROLOGY, 51(1) 22-29, Jan, 2016 Peer-reviewed
Reduced Abundance of Butyrate-Producing Bacteria Species in the Fecal Microbial Community in Crohn's Disease

Kenichiro Takahashi, Atsushi Nishida, Takehide Fujimoto, Makoto Fujii, Makoto Shioya, Hirotsugu Innaeda, Osamu Lnatorni, Shigeki Bamba, Akira Andoh, Mitsushige Sugimoto

DIGESTION, 93(1) 59-65, 2016 Peer-reviewed
Interleukin (IL)-1 beta Is a Strong Inducer of IL-36. Expression in Human Colonic Myofibroblasts

Kenichiro Takahashi, Atsushi Nishida, Makoto Shioya, Hirotsugu Imaeda, Shigeki Bamba, Osamu Inatomi, Tomoharu Shimizu, Katsuyuki Kitoh, Akira Andoh

PLOS ONE, 10(11) e0138423, Nov, 2015 Peer-reviewed
Cases of three patients with gastric cancer and metastasis to the skeletal muscle

Yoshihiko Sugitani, Osamu Inatomi, Rie Tanabe, Toshihiro Kanda, Ayano Sonoda, Hiroshi Hasegawa, Rie Osaki, Hirotsugu Imaeda, Hiromitsu Ban, Atsushi Nishida …

Japanese Journal of Cancer and Chemotherapy, 42(11) 1419-1421, Nov 1, 2015 Peer-reviewed
Factors affecting pancreatic hyperamylasemia in patients undergoing peroral single-balloon enteroscopy

Tomoyuki Tsujikawa, Shigeki Bamba, Osamu Inatomi, Hiroshi Hasegawa, Hiromitsu Ban, Atsushi Nishida, Hirotsugu Imaeda, Akihiko Itoh, Takao Saotome, Masaya Sasaki …

DIGESTIVE ENDOSCOPY, 27(6) 674-678, Sep, 2015 Peer-reviewed
A case of Crohn's disease that developed anti-infliximab and anti-adalimumab antibodies.

Kenichiro Takahashi, Takehide Fujimoto, Makoto Shioya, Atsushi Nishida, Shigeki Bamba, Osamu Inatomi, Hirotsugu Imaeda, Katsuyuki Kitoh, Akira Andoh

Clinical journal of gastroenterology, 8(2) 88-91, Apr, 2015 Peer-reviewed
Familial and Multiple Gastrointestinal Stromal Tumors with Fair Response to a Half-dose of Imatinib

Shigeki Bamba, Seiichi Hirota, Osamu Inatomi, Hiromitsu Ban, Takashi Nishimura, Makoto Shioya, Hirotsugu Imaeda, Atsushi Nishida, Masaya Sasaki, Satoshi Murata …

INTERNAL MEDICINE, 54(7) 759-764, 2015 Peer-reviewed
Interleukin(IL)-36α and IL-36γ Induce Proinflammatory Mediators from Human Colonic Subepithelial Myofibroblasts.

Toshihiro Kanda, Atsushi Nishida, Kenichiro Takahashi, Kentaro Hidaka, Hirotsugu Imaeda, Osamu Inatomi, Shigeki Bamba, Mitsushige Sugimoto, Akira Andoh

Frontiers in medicine, 2 69-69, 2015 Peer-reviewed
Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease

Yusuke Honzawa, Hiroshi Nakase, Masahiro Shiokawa, Takuya Yoshino, Hirotsugu Imaeda, Minoru Matsuura, Yuzo Kodama, Hiroki Ikeuchi, Akira Andoh, Yoshiharu Sakai …

GUT, 63(12) 1902-1912, Dec, 2014 Peer-reviewed
Involvement of interleukin-17A-induced expression of heat shock protein 47 in intestinal fibrosis in Crohn's disease

Yusuke Honzawa, Hiroshi Nakase, Masahiro Shiokawa, Takuya Yoshino, Hirotsugu Imaeda, Minoru Matsuura, Yuzo Kodama, Hiroki Ikeuchi, Akira Andoh, Yoshiharu Sakai …

GUT, 63(12) 1902-1912, Dec, 2014 Peer-reviewed
Predicting Mucosal Healing in Crohn's Disease Using Practical Clinical Indices with Regard to the Location of Active Disease

Shigeki Bamba, Tomoyuki Tsujikawa, Hiromitsu Ban, Hirotsugu Imaeda, Osamu Inatomi, Atsushi Nishida, Masaya Sasaki, Akira Andoh, Yoshihide Fujiyama

HEPATO-GASTROENTEROLOGY, 61(131) 689-696, May, 2014 Peer-reviewed

Misc.

病態解析に基づく実現性の高い治療戦略─日本人特有のチオプリン高感受性遺伝子の同定とテーラーメイド医療の展開.

Intestine, 15(3) 2-9, 2011

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