Aug, 2013 - Mar, 2015
Association of heart rate variability with silent cerebral lesions in a Japanese general population: a cross-sectional cohort study
Japan Society for the Promotion of Science Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up Grant-in-Aid for Research Activity Start-up
- Grant number
- 25893097
- Japan Grant Number (JGN)
- JP25893097
- Grant amount
-
- (Total)
- 2,730,000 Japanese Yen
- (Direct funding)
- 2,100,000 Japanese Yen
- (Indirect funding)
- 630,000 Japanese Yen
Heart rate variability (HRV) reflects the autonomic nervous system. Little is known regarding the association of HRV with stroke risk in a general population. We conducted a cross-sectional study in a population-based sample of apparently healthy Japanese men to examine the association of nighttime (2 am to 2:15 am) and 24-hour HRV indices (SDNN, LF, HF, LF/HF ratio) quantified by 24-hour electrocardiogram with silent cerebral lesions (lacunar infarcts, microbleeds, white matter hyperintensities, brain artery stenoses) evaluated by brain magnetic resonance imaging. We found no significant associations between these HRV indices and silent cerebral lesions. In conclusion, in a community-based sample of Japanese men without clinical cardiovascular disease, HRV was not associated with silent cerebral lesions.
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- ID information
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- Grant number : 25893097
- Japan Grant Number (JGN) : JP25893097