論文

査読有り
2008年

Algorithms and complexity analyses for control of singleton attractors in Boolean networks

Eurasip Journal on Bioinformatics and Systems Biology
  • Takeyuki Tamura
  • ,
  • Morihiro Hayashida
  • ,
  • Tatsuya Akutsu
  • ,
  • Shu-Qin Zhang
  • ,
  • Wai-Ki Ching

2008
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.1155/2008/521407

A Boolean network (BN) is a mathematical model of genetic networks. We propose several algorithms for control of singleton attractors in BN. We theoretically estimate the average-case time complexities of the proposed algorithms, and confirm them by computer experiments. The results suggest the importance of gene ordering. Especially, setting internal nodes ahead yields shorter computational time than setting external nodes ahead in various types of algorithms. We also present a heuristic algorithm which does not look for the optimal solution but for the solution whose computational time is shorter than that of the exact algorithms.

リンク情報
DOI
https://doi.org/10.1155/2008/521407
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/18795107
ID情報
  • DOI : 10.1155/2008/521407
  • ISSN : 1687-4145
  • ISSN : 1687-4153
  • PubMed ID : 18795107
  • SCOPUS ID : 52949100547

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