2005年
Analysis of arf interaction with GGAs in vitro and in vivo
GTPASES REGULATING MEMBRANE DYNAMICS
- ,
- 巻
- 404
- 号
- 開始ページ
- 367
- 終了ページ
- 377
- 記述言語
- 英語
- 掲載種別
- 論文集(書籍)内論文
- DOI
- 10.1016/S0076-6879(05)04032-2
- 出版者・発行元
- ELSEVIER ACADEMIC PRESS INC
Small GTPases of the ADP-ribosylation factor (Arf) family regulate membrane traffic and dynamics in eukaryotic cells. GGAs (Golgi-localizing, gamma-adaptin ear homology domain, Arf-binding proteins) are a family of monomeric clathrin adaptor proteins that were originally identified as proteins interacting with Arfs and found to associate mainly with membranes of the trans-Golgi network (TGN). Like other adaptor and coat proteins, membrane association of GGAs is regulated by Arfs in a GTP-dependent manner. Together with or independent of the adaptor protein complex AP-1, GGAs mediate sorting of transmembrane proteins, including mannose 6-phosphate receptors, between the TGN and endosomes by clathrin-coated vesicles. This chapter describes methods to examine the interaction between Arfs and GGAs and to analyze the cellular function of GGAs regulated by Arfs.
- リンク情報
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- DOI
- https://doi.org/10.1016/S0076-6879(05)04032-2
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/16413283
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000234565700032&DestApp=WOS_CPL
- URL
- http://www.scopus.com/inward/record.url?eid=2-s2.0-30544440892&partnerID=MN8TOARS
- URL
- http://orcid.org/0000-0001-7701-7183
- ID情報
-
- DOI : 10.1016/S0076-6879(05)04032-2
- ISSN : 0076-6879
- ORCIDのPut Code : 44277959
- PubMed ID : 16413283
- SCOPUS ID : 30544440892
- Web of Science ID : WOS:000234565700032