Akira Kakizuka

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Name
Akira Kakizuka
Affiliation
Kyoto University

Published Papers

 
Muraoka Y, Iida Y, Ikeda HO, Iwai S, Hata M, Iwata T, Nakayama M, Shimozawa N, Katakai Y, Kakizuka A, Yoshimura N, Tsujikawa A
Heliyon   4(5) e00624   May 2018   [Refereed]
Alfaqaan S, Yoshida T, Imamura H, Tsukano C, Takemoto Y, Kakizuka A
Scientific reports   9(1) 4538   Mar 2019   [Refereed]
Hasegawa T, Ikeda HO, Iwai S, Muraoka Y, Tsuruyama T, Okamoto-Furuta K, Kohda H, Kakizuka A, Yoshimura N
Heliyon   4(2) e00544   Feb 2018   [Refereed]
Sasaoka N, Imamura H, Kakizuka A
iScience   10 211-221   Dec 2018   [Refereed]
Matsubara M, Kanda H, Imamura H, Inoue M, Noguchi M, Hosoda K, Kakizuka A, Nakao K
Scientific reports   8(1) 949   Jan 2018   [Refereed]
Nie X, Kitaoka S, Tanaka K, Segi-Nishida E, Imoto Y, Ogawa A, Nakano F, Tomohiro A, Nakayama K, Taniguchi M, Mimori-Kiyosue Y, Kakizuka A, Narumiya S, Furuyashiki T
Neuron   99(3) 464-479.e7   Aug 2018   [Refereed]
Hasegawa T, Ikeda HO, Iwai S, Muraoka Y, Tsuruyama T, Okamoto-Furuta K, Kohda H, Kakizuka A, Yoshimura N
Heliyon   4(8) e00739   Aug 2018   [Refereed]
Tanaka S, Yoshioka S, Nishida K, Hosokawa H, Kakizuka A, Maegawa S
Scientific reports   8(1) 11423   Jul 2018   [Refereed]
Sugiyama Y, Shudo T, Hosokawa S, Watanabe A, Nakano M, Kakizuka A
Genes to cells : devoted to molecular & cellular mechanisms      Jun 2019   [Refereed]
Ohnuma Y, Takata T, Kawawaki J, Yasuda K, Tanaka K, Kimura Y, Kakizuka A
FEBS letters   589(5) 576-580   Feb 2015   [Refereed]
Suppression of Drusen-like Deposits by a Novel VCP modulator in CCR2 Deficient Mice
Muraoka Yuki, Ikeda Hanako Ohashi, Iida Yuto, Hata Masayuki, Hasegawa Tomoko, Yoshikawa Munemitsu, Kakizuka Akira, Yoshimura Nagahisa
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE   56(7)    Jun 2015   [Refereed]
Yaginuma H, Kawaie S, Kazuhito V. Tabata KV, Tomiyama K, Kakizuka A, Komatsuzaki T, Hiroyuki Noji H, & Imamura H
Scientific Reports   4 6522   Oct 2014   [Refereed]
Ikeda H, Sasaoka N, Koike M, Nakano N, Muraoka Y, Toda Y, Fuchigami T, Shudo T, Iwata A, Hori S, Yoshimura N, & Kakizuka A.
Scientific Reports   4 5970   Aug 2014   [Refereed]
T. Tanaka; K. Nagashima; N. Inagaki; H. Kioka; S. Takashima; H. Fukuoka; H. Noji; A. Kakizuka; H. Imamura
Journal of Biological Chemistry   289(4) 2205-2216   Jan 2014   [Refereed]
Neuroprotective effect of KUS121, a VCP modulator, on a rat model of ischemia and reperfusion-induced retinal degeneration.
Hata Masayuki, Ikeda Hanako Ohashi, Yoshikawa Munemitsu, Hasegawa Tomoko, Nakano Noriko, Muraoka Yuki, Kakizuka Akira, Yoshimura Nagahisa
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE   55(13)    Apr 2014   [Refereed]
Konagaya Y, Terai K, Hirao Y, Takakura K, Imajo M, Kamioka Y, Sasaoka N, Kakizuka A, Sumiyama K, Asano T, Matsuda M
Cell reports   21(9) 2628-2638   Nov 2017   [Refereed]
Sasaoka N, Sakamoto M, Kanemori S, Tsukano C, Takemoto Y, & Kakizuka A.
PLoS One   9(1) e87185   Jan 2014   [Refereed]
Suppression of Drusen-like Deposits by a Novel VCP modulator in CCR2 Deficient Mice
Muraoka Yuki, Ikeda Hanako Ohashi, Nakano Noriko, Hasegawa Tomoko, Hata Masayuki, Yoshikawa Munemitsu, Kakizuka Akira, Yoshimura Nagahisa
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE   55(13)    Apr 2014   [Refereed]
Nakano M, Imamura H, Sasaoka N, Yamamoto M, Uemura N, Shudo T, Fuchigami T, Takahashi R, Kakizuka A
EBioMedicine   22 225-241   Aug 2017   [Refereed]
K. Yasuda; K. Ohyama; K. Onga; A. Kakizuka; N. Mori
PLoS ONE   8(12) e82523   Dec 2013   [Refereed]
Hata M, Ikeda HO, Kikkawa C, Iwai S, Muraoka Y, Hasegawa T, Kakizuka A, Yoshimura N
Scientific reports   7 44873   Mar 2017   [Refereed]
Y. Kimura; J. Fukushi; S. Hori; N. Matsuda; K. Okatsu; Y. Kakiyama; J. Kawawaki; A. Kakizuka; K. Tanaka
Genes to Cells   18(12) 1131-1143   Dec 2013   [Refereed]
Yoshida T, Kakizuka A, Imamura H
Scientific reports   6 39618   Dec 2016   [Refereed]
Hasegawa T, Muraoka Y, Ikeda HO, Tsuruyama T, Kondo M, Terasaki H, Kakizuka A, Yoshimura N
Scientific reports   6 31184   Aug 2016   [Refereed]
Neuroprotective effect of VCP inhibitors on mice models of glaucoma
Ikeda Hanako, Nakano Noriko, Muraoka Yuki, Hangai Masanori, Kakizuka Akira, Yoshimura Nagahisa
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE   54(15)    Jun 2013   [Refereed]
Ikura M, Furuya K, Fukuto A, Matsuda R, Adachi J, Matsuda T, Kakizuka A, Ikura T
Molecular and cellular biology   36(10) 1595-1607   May 2016   [Refereed]
A Novel Valosin-Containing Protein Inhibitor Suppresses Photoreceptor Degeneration in a Rabbit Model of Retinitis Pigmentosa
Muraoka Yuki, Ikeda Hanako, Nakano Noriko, Hasegawa Tomoko, Kakizuka Akira, Yoshimura Nagahisa
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE   54(15)    Jun 2013   [Refereed]
Nakano N, Ikeda HO, Hasegawa T, Muraoka Y, Iwai S, Tsuruyama T, Nakano M, Fuchigami T, Shudo T, Kakizuka A, Yoshimura N
Heliyon   2(4) e00096   Apr 2016   [Refereed]
Matsuda S, Adachi J, Ihara M, Tanuma N, Shima H, Kakizuka A, Ikura M, Ikura T, Matsuda T
Nucleic acids research   44(2) 636-647   Jan 2016   [Refereed]
Ohtera A, Miyamae Y, Yoshida K, Maejima K, Akita T, Kakizuka A, Irie K, Masuda S, Kambe T, Nagao M
ACS chemical biology   10(12) 2794-2804   Dec 2015   [Refereed]
Kakizuka A, Nakao K, Minato N, Uemoto S
   2015   [Refereed]
T. Tsuyama; J.-I. Kishikawa; Y.-W. Han; Y. Harada; A. Tsubouchi; H. Noji; A. Kakizuka; K. Yokoyama; T. Uemura; H. Imamura
Analytical Chemistry   85(16) 7889-7896   Aug 2013   [Refereed]
A.T. Ehrlich; T. Furuyashiki; S. Kitaoka; A. Kakizuka; S. Narumiya
Molecular Pharmacology   84(3) 476-486   Sep 2013   [Refereed]
Murakami, Katsuhiro;Ichinohe, Yuzuru;Koike, Masaaki;Sasaoka, Norio;Iemura, Shun-ichiro;Natsume, Tohru;Kakizuka, Akira
PloS one   8(2) e56012   Feb 2013   [Refereed]
H. Sakurai; Y. Sakaguchi; E. Shoji; T. Nishino; I. Maki; H. Sakai; K. Hanaoka; A. Kakizuka; A. Sehara-Fujisawa
PLoS ONE   7(10) e47078   Oct 2012   [Refereed]
T. Takata; Y. Kimura; Y. Ohnuma; J. Kawawaki; Y. Kakiyama; K. Tanaka; A. Kakizuka
Journal of Structural Biology   179(2) 93-103   Aug 2012   [Refereed]
Y. Muraoka; H.O. Ikeda; N. Nakano; M. Hangai; Y. Toda; K. Okamoto-Furuta; H. Kohda; M. Kondo; H. Terasaki; A. Kakizuka; N. Yoshimura
PLoS ONE   7(4) e36135   Apr 2012   [Refereed]
K. Ohyama; K. Yasuda; K. Onga; A. Kakizuka; N. Mori
Gene Expression Patterns   12(1-2) 36-45   Jan 2012   [Refereed]
N. Nakano; H.O. Ikeda; M. Hangai; Y. Muraoka; Y. Toda; A. Kakizuka; N. Yoshimura
Investigative Ophthalmology and Visual Science   52(12) 8754-8762   Nov 2011   [Refereed]
Y. Takeshita; R. Fujinaga; K. Kokubu; M.N. Islam; M.R. Jahan; A. Yanai; A. Kakizuka; K. Shinoda
NeuroReport   22(5) 232-238   Mar 2011   [Refereed]
A. Manno; M. Noguchi; J. Fukushi; Y. Motohashi; A. Kakizuka
Genes to Cells   15(8) 911-922   Aug 2010   [Refereed]
K. Muguruma; A. Nishiyama; Y. Ono; H. Miyawaki; E. Mizuhara; S. Hori; A. Kakizuka; K. Obata; Y. Yanagawa; T. Hirano; Y. Sasai
Nature Neuroscience   13(10) 1171-1180   Oct 2010   [Refereed]
M. Koike; J. Fukushi; Y. Ichinohe; N. Higashimae; M. Fujishiro; C. Sasaki; M. Yamaguchi; T. Uchihara; S. Yagishita; H. Ohizumi; S. Hori; A. Kakizuka
Journal of Biological Chemistry   285(28) 21736-21749   Jul 2010   [Refereed]
A. Okamoto; M. Koike; K. Yasuda; A. Kakizuka
Biochemical and Biophysical Research Communications   394(1) 42-47   Mar 2010   [Refereed]
T. Shintani; F. Yamazaki; T. Katoh; M. Umekawa; Y. Matahira; S. Hori; A. Kakizuka; K. Totani; K. Yamamoto; H. Ashida
Biochemical and Biophysical Research Communications   391(4) 1775-1779   Jan 2010   [Refereed]
Y. Kimura; H. Yashiroda; T. Kudo; S. Koitabashi; S. Murata; A. Kakizuka; K. Tanaka
Cell   137(3) 549-559   May 2009   [Refereed]
C. Mori-Konya; N. Kato; R. Maeda; K. Yasuda; N. Higashimae; M. Noguchi; M. Koike; Y. Kimura; H. Ohizumi; S. Hori; A. Kakizuka
Genes to Cells   14(4) 483-497   Apr 2009   [Refereed]
Y. Yoshikawa; M. Ogawa; T. Hain; M. Yoshida; M. Fukumatsu; M. Kim; H. Mimuro; I. Nakagawa; T. Yanagawa; T. Ishii; A. Kakizuka; E. Sztul; T. Chakraborty; C. Sasakawa
Nature Cell Biology   11(10) 1233-1240   Oct 2009   [Refereed]
R. Nomura; Y. Suzuki; A. Kakizuka; H. Jingami
Journal of Biological Chemistry   283(8) 4665-4673   Feb 2008   [Refereed]
A. Kakizuka
Biochemical Society Transactions   36(Pt 1) 105-108   Feb 2008   [Refereed]
T. Kobayashi; A. Manno; A. Kakizuka
Genes to Cells   12(7) 889-901   Jul 2007   [Refereed]
H. Matsushita; P.P. Scaglioni; M. Bhaumik; E.M. Rego; F.C. Lu; S.M. Majid; H. Miyachi; A. Kakizuka; W.H. Miller Jr.; P.P. Pandolfi
Journal of Experimental Medicine   203(4) 821-828   Apr 2006   [Refereed]
[Protein modifications in neurodegenerative disorders].
Kakizuka A, Koike M
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   52(7) 768-773   Jun 2007   [Refereed]
A.-H. Chou; T.-H. Yeh; Y.-L. Kuo; Y.-C. Kao; M.-J. Jou; C.-Y. Hsu; S.-R. Tsai; A. Kakizuka; H.-L. Wang
Neurobiology of Disease   21(2) 333-345   Feb 2006   [Refereed]
[Neurodegenerative disorder and the nucleus].
Kakizuka A
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   51(14 Suppl) 2269-2273   Nov 2006   [Refereed]
M.-I. Kitami; T. Kitami; M. Nagahama; M. Tagaya; S. Hori; A. Kakizuka; Y. Mizuno; N. Hattori
FEBS Letters   580(2) 474-478   Jan 2006   [Refereed]
M. Noguchi; T. Takata; Y. Kimura; A. Manno; K. Murakami; M. Koike; H. Ohizumi; S. Hori; A. Kakizuka
Journal of Biological Chemistry   280(50) 41332-41341   Dec 2005   [Refereed]
Y.A. Wang; K. Shen; Y. Ishida; Y. Wang; A. Kakizuka; S.C. Brooks
Molecular Carcinogenesis   44(4) 252-261   Dec 2005   [Refereed]
T. Shiraki; N. Kamiya; S. Shiki; T.S. Kodama; A. Kakizuka; H. Jingami
Journal of Biological Chemistry   280(14) 14145-14153   Apr 2005   [Refereed]
W.-L. Liao; H.-F. Wang; H.-C. Tsai; P. Chambon; M. Wagner; A. Kakizuka; F.-C. Liu
Developmental Dynamics   232(4) 887-900   Apr 2005   [Refereed]
Y. Kimura; S. Koitabashi; A. kakizuka; T. Fujita
Genes to Cells   9(8) 685-696   Aug 2004   [Refereed]
[Neurodegenerative disorders as protein misfolding diseases and organelle diseases].
Kakizuka A, Mori M
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   49(7 Suppl) 1077-1085   May 2004   [Refereed]
[Therapeutic targets in polyglutamine diseases].
Hori S, Kakizuka A
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   49(7 Suppl) 1118-1121   May 2004   [Refereed]
H. Maeda; S. Hori; H. Ohizumi; T. Segawa; Y. Kakehi; O. Ogawa; A. Kakizuka
Cell Death and Differentiation   11(7) 737-746   2004   [Refereed]
D. Goti; S.M. Katzen; J. Mez; N. Kurtis; J. Kiluk; L. Ben-Haïem; N.A. Jenkins; N.G. Copeland; A. Kakizuka; A.H. Sharp; C.A. Ross; P.R. Mouton; V. Colomer
Journal of Neuroscience   24(45) 10266-10279   Nov 2004   [Refereed]
M. Matsumoto; M. Yada; S. Hatakeyama; H. Ishimoto; T. Tanimura; S. Tsuji; A. Kakizuka; M. Kitagawa; K.I. Nakayama
EMBO Journal   23(3) 659-669   Feb 2004   [Refereed]
A. Sato; M. Imaizumi; Y. Hoshi; T. Rikiishi; K. Fujii; M. Kizaki; H. Kagechika; A. Kakizuka; Y. Hayashi; K. Iinuma
Leukemia Research   28(9) 959-967   Sep 2004   [Refereed]
Y. Kimura; A. Kakizuka
IUBMB Life   55(6) 337-345   Jun 2003   [Refereed]
S. Ishigaki; N. Hishikawa; J.-I. Niwa; S.-I. Iemura; T. Natsume; S. Hori; A. Kakizuka; K. Tanaka; G. Sobue
Journal of Biological Chemistry   279(49) 51376-51385   Dec 2004   [Refereed]
T. Kobayashi; A. Kakizuka
Cytogenetic and Genome Research   100(1-4) 261-275   2003   [Refereed]
Y. Mizuno; S. Hori; A. Kakizuka; K. Okamoto
Neuroscience Letters   343(2) 77-80   Jun 2003   [Refereed]
A challenge for revealing common molecular mechanisms underlying neurodegenerative disorders
A. Kakizuka
Clinical Neurology   42(11) 1054-1063   Nov 2002   [Refereed]
T. Kobayashi; K. Tanaka; K. Inoue; A. Kakizuka
Journal of Biological Chemistry   277(49) 47358-47365   Dec 2002   [Refereed]
Y. Kimura; S. Koitabashi; A. Kakizuka; T. Fujita
Journal of Biological Chemistry   277(40) 37536-37541   Oct 2002   [Refereed]
H. Nishitoh; A. Matsuzawa; K. Tobiume; K. Saegusa; K. Takeda; K. Inoue; S. Hori; A. Kakizuka; H. Ichijo
Genes and Development   16(11) 1345-1355   Jun 2002   [Refereed]
M. Nakamoto; S. Nakano; S. Kawashima; M. Ihara; Y. Nishimura; A. Shinde; A. Kakizuka
Archives of Neurology   59(3) 474-477   Mar 2002   [Refereed]
H. Higashiyama; F. Hirose; M. Yamaguchi; Y.H. Inoue; N. Fujikake; A. Matsukage; A. Kakizuka
Cell Death and Differentiation   9(3) 264-273   2002   [Refereed]
Tumor growth inhibition by arsenic trioxide (As2O3) in the orthotopic metastasis model of androgen-independent prostate cancer
H. Maeda; S. Hori; H. Nishitoh; H. Ichijo; O. Ogawa; Y. Kakehi; A. Kakizuka
Cancer Research   61(14) 5432-5440   2001   [Refereed]
Y. Yamamoto; H. Hasegawa; K. Tanaka; A. Kakizuka
Cell Death and Differentiation   8(8) 871-873   2001   [Refereed]
M. Hirabayashi; K. Inoue; K. Tanaka; K. Nakadate; Y. Ohsawa; Y. Kamei; A.H. Popiel; A. Sinohara; A. Iwamatsu; Y. Kimura; Y. Uchiyama; S. Hori; A. Kakizuka
Cell Death and Differentiation   8(10) 977-984   2001   [Refereed]
Y. Kimura; S. Koitabashi; A. Kakizuka; T. Fujita
Genes to Cells   6(10) 887-897   2001   [Refereed]
Approaches from genetical analyses on human diseases: neurodegenerative diseases
A. Kakizuka
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme   45(6 Suppl) 792-797   2000   [Refereed]
H. Maeda; T. Segawa; T. Kamoto; H. Yoshida; A. Kakizuka; O. Ogawa; Y. Kakehi
Prostate   45(4) 335-340   2000   [Refereed]
S. Yasuda; K. Inoue; M. Hirabayashi; H. Higashiyama; Y. Yamamoto; H. Fuyuhiro; O. Komure; F. Tanaka; G. Sobue; K. Tsuchiya; K. Hamada; H. Sasaki; K. Takeda; H. Ichijo; A. Kakizuka
Genes to Cells   4(12) 743-756   Dec 1999   [Refereed]
Sanchez, I; Xu, CJ; Juo, P; Kakizaka, A; Blenis, J; Yuan, JY
NEURON   22(3) 623-633   Mar 1999   [Refereed]
A. Kakizuka
Trends in Genetics   14(10) 396-402   Oct 1998   [Refereed]
Mutations in the E-domain of RARα portion of the PML/RARα chimeric gene may confer clinical resistance to all-trans retinoic acid in acute promyelocytic leukemia
M. Imaizumi; H. Suzuki; M. Yoshinari; A. Sato; T. Saito; A. Sugawara; S. Tsuchiya; Y. Hatae; T. Fujimoto; A. Kakizuka; T. Konno; K. Linuma
Blood   92(2) 374-382   1998   [Refereed]
Recent progress in the research field on triplet repeat diseases
A. Kakizuka
Clinical Neurology   38(12) 988-992   1998   [Refereed]
Structure of the retinoic acid receptor and its functional analysis using a mutated receptor
A. Kakizuka
Nippon rinsho. Japanese journal of clinical medicine   56(7) 1711-1716   1998   [Refereed]
Prostate-specific amplification of expanded polyglutamine expression: A novel approach for cancer gene therapy
T. Segawa; H. Takebayashi; Y. Kakehi; O. Yoshida; S. Narumiya; A. Kakizuka
Cancer Research   58(11) 2282-2287   1998   [Refereed]
Fas and mutant estrogen receptor chimeric gene: A novel suicide vector for tamoxifen-inducible apoptosis
H. Kodaira; A. Kume; Y. Ogasawara; M. Urabe; K. Kitano; A. Kakizuka; K. Ozawa
Japanese Journal of Cancer Research   89(7) 741-747   1998   [Refereed]
C.L. Wellington; L.M. Ellerby; A.S. Hackam; R.L. Margolis; M.A. Trifiro; R. Singaraja; K. McCutcheon; G.S. Salvesen; S.S. Propp; M. Bromm; K.J. Rowland; T. Zhang; D. Rasper; S. Roy; N. Thornberry; L. Pinsky; A. Kakizuka; C.A. Ross; D.W. Nicholson; D.E. Bredesen; M.R. Hayden
Journal of Biological Chemistry   273(15) 9158-9167   1998   [Refereed]
M. Kokubun; A. Kume; M. Urabe; H. Mano; M. Okubo; R. Kasukawa; A. Kakizuka; K. Ozawa
Gene Therapy   5(7) 923-929   1998   [Refereed]
K.-Y. Hasumoto; Y. Sugimoto; M. Gotoh; E. Segi; A. Yamasaki; M. Yamaguchi; H. Honda; H. Hirai; M. Negishi; A. Kakizuka; A. Ichikawa; S. Nakanishi
Genes to Cells   2(9) 571-580   Sep 1997   [Refereed]
Y. Kawaguchi; H. Takebayashi; A. Kakizuka; S. Arii; M. Kato; M. Imamura
Cancer Letters   116(1) 53-59   Jun 1997   [Refereed]
N. Watanabe; P. Madaule; T. Reid; T. Ishizaki; G. Watanabe; A. Kakizuka; Y. Saito; K. Nakao; B.M. Jockusch; S. Narumiya
EMBO Journal   16(11) 3044-3056   Jun 1997   [Refereed]
F. Suzuki; S. Miyamoto; M. Takita; M. Oshita; Y. Watanabe; A. Kakizuka; S. Narumiya; T. Taniguchi; I. Muramatsu
Biochimica et Biophysica Acta - Biomembranes   1323(1) 6-11   Jan 1997   [Refereed]
Association of expression of mRNA encoding the PGF(2α) receptor with luteal cell apoptosis in ovaries of pseudopregnant mice
K. Hasumoto; Y. Sugimoto; A. Yamasaki; K. Morimoto; A. Kakizuka; M. Negishi; A. Ichikawa
Journal of Reproduction and Fertility   109(1) 45-51   Jan 1997   [Refereed]
Degenerative ataxias : pathogenesis, genetics, and disease models
垣塚 彰
Current opinion in neurology,10/,285-290      1997   [Refereed]
M. Nakamoto; H. Takebayashi; Y. Kawaguchi; S. Narumiya; M. Taniwaki; Y. Nakamura; Y. Ishikawa; I. Akiguchi; J. Kimura; A. Kakizuka
Nature genetics   17(4) 385-386   1997   [Refereed]

Misc

 
Protective effect of B101, a mixture of nutrients, in a retinal degeneration mouse model
Hasegawa T, Hanako O Ikeda- Ohhashi H, Hata M, Muraoka Y, Kakizuka A, & Yoshimura N.
Asia ARVO 2015      Feb 2015   [Refereed]
VCP, a major ATPase in the cells, as a novel drug target for currently incurable disorders.
Akira Kakizuka
7th Asian Aging Core for Longevity conference in Jeju      Sep 2014   [Refereed][Invited]
Neuroprotective effects of a VCP modulator on rat models of ischemia and reperfusion-induced retinal degeneration.
Hata M, Ikeda-Ohhashi H, Hasegawa T, Nakano N, Muraoka Y, Kakizuka A, & Yoshimura N.
ARVO2014      May 2014   [Refereed]
Neuroprotective effect of a valosin-containing-protein ATPase inhibitor on late-stage retinal degeneration in a mouse model.
Hasegawa T, Hanako O. Ikeda-Ohhashi H, Muraoka Y, KakizukaA, & Yoshimura N.
World Ophthalmology Congress      Apr 2014   [Refereed]
Novel VCP modulators for the treatment of incurable eye diseases
Akira Kakizuka
BioJapan 2013      Oct 2013   [Refereed][Invited]
Novel VCP modulators mitigate major pathologies in mouse models of glaucoma and retinitis pigmentosa by their neuroprotective effects.
Akira Kakizuka
EMBO workshop “AAA+ proteins      Sep 2013   [Refereed][Invited]
Imaging of intracellular ATP dynamics in single apoptotic cells.
Shu-ichiro Sakamoto, Akira Kakizuka, & Hiromi Imamura.
The 11th International Student Seminar      Mar 2013   [Refereed]
Regulation of autophagosome formation by Golgi dyanamics via CDC2-p37/p47/VCP axis
Yuko Ito, Masaaki Koike, & Akira Kakizuka.
The 11th International Student Seminar(ポスター発表)      Mar 2013   [Refereed]
Fluorescent ATP biosensor optimized for imaging of cells from non-vertebrate model organisms
Hiromi Imamura, Taiichi Tsuyama, Tadashi Uemura, & Akira Kakizuka.
International Symposia "New Frontiers of Metabolism Research in Biomedical Sciences"      Sep 2012   [Refereed]
Genetically-encoded ATP biosensor for low temperatures
Hiromi Imamura, Taiichi Tsuyama, Jun-ichi Kishikawa, Hiroyuki Noji, Akira Kakizuka, Ken Yokoyama, & Tadashi Uemura.
European Bioenergetic Conference 2012(ポスター発表)      Sep 2012   [Refereed]
Neuroprotective effects of VCP inhibitors on DBA/2J mice, a mouse model of glaucoma
Hanako Ikeda, Noriko Nakano, Yuki Muraoka, Masanori Hangai, Akira Kakizuka, & Nagahisa Yoshimura.
第23回日本緑内障学会      Sep 2012   [Refereed]
Simultaneous ATP and Ca2+ imaging of a single insulin-secreting islet cell.
Takashi Tanaka, Kazuaki Nagashima, Nobuya Inagaki, Hiroyuki Noji, Akira Kakizuka, & Hiromi Imamura
The 10th International Student Seminar      Mar 2012   [Refereed]
Roles of ADAM10/kuzbanian in vasculogenesis of \nzebrafish.
Tomosawa Anna, Atsuo Iida, Akira Kakizuka, Atsuko Sehara.
第34 回日本分子生物学会年会(2011.12.13 神奈川)      Dec 2011   [Refereed]
Development for novel drugs for Alzheimer disease and glaucoma.
Akira Kakizuka
第88回日本生理学会大会・第116回日本解剖学会総会・全国学術集会(ポスター発表)      Oct 2011   [Refereed]
Involvement of MAGl1 and c-fos in schizophrenia like behavioral abnormality.
Sachi Tsujikawa, Keizo Takao, Tsuyoshi Miyakawa, Haruaki Ninomiya, Tomoh Masaki, & Akira Kakizuka
第84回日本生化学会大会(22日口頭、23日ポスター発表)      Sep 2011   [Refereed]
Deficiency of sensory motor gating in MAGI-1 knockout mice
Sachi Tsujikawa, Keizo Takao, Kazuo Nakanishi, Tsuyoshi Miyakawa, Akira Kakizuka, Haruaki Ninomiya, Tomoh Masaki, & Hiroshi Hosokawa
第88回日本生理学会大会・第116回日本解剖学会総会・全国学術集会      Mar 2011   [Refereed]
MAGI-1 modulates anxiety-like behavior in mice
Sachi Tsujikawa, Yukio Taniguchi, Keizo Takao, Tsuyoshi Miyakawa, Shingo Maegawa, Shigeo Kobayashi, Haruaki Ninomiya, Tomoh Masaki, Akira Kakizuka, & Hiroshi Hosokawa.
BMB2010      Dec 2010   [Refereed]
A comprehensive study \non expression patterns of zebrafish ADAM genes(ゼブラフィッシュADAM 遺伝子の包括的発現解析),
Kazuya Sakaguchi, Tomomi Sato, Atsuo Iida, Naoki Irie, Akira Kakizuka, Atsuko Sehara.
),43 rd anual Meeting for the Japanese Society of Developmentai Biokigists Jointly Sponsored by the Asia-Pacific Developmental Biology Network(第43 回日本発生生物学会年会)(2010.6.21 京都)      2010   [Refereed]
Involvement of VCP/p97 and co-factors in the formation of abnormal protein aggregates.
Atsushi Manno Masakatsu Noguchi, Junpei Fukushi, Yasuhiro Motohashi, Katsuhiro Murakami, & Akira Kakizuka
The 6th international student Seminar      Mar 2008   [Refereed]
Analysis of the epitope of an ER-residing VCP.
Mariko Hamaguchi, Atsushi Manno & Akira Kkaizuka
The 6th international student Seminar      Mar 2008   [Refereed]
Modificaions of VCP via abnormal protein accumulation lead to neuronal cell atrophy and neurodegeneration.
Masaaki Koike, Naoki Higashimae, Masahiko Fujishiro, Junpei Fukushi, & Akira Kkaizuka
7th international conference on AAA proteins      Sep 2007   [Refereed]
Y. Kamei; H. Ohizumi; Y. Fujitani; T. Nemoto; T. Tanaka; N. Takahashi; T. Kawada; M. Miyoshi; O. Ezaki; A. Kakizuka
Proceedings of the National Academy of Sciences of the United States of America   100(21) 12378-12383   2003   [Refereed]
M. Yamaguchi; M. Nakamoto; H. Honda; T. Nakagawa; H. Fujita; T. Nakamura; H. Hirai; S. Narumiya; A. Kakizuka
Proceedings of the National Academy of Sciences of the United States of America   95(13) 7491-7496   1998   [Refereed]
E. Early; M.A.S. Moore; A. Kakizuka; K. Nason-Burchenal; P. Martin; R.M. Evans; E. Dmitrovsky
Proceedings of the National Academy of Sciences of the United States of America   93(15) 7900-7904   1996   [Refereed]
M. Hirata; A. Kakizuka; M. Aizawa; F. Ushikubi; S. Narumiya
Proceedings of the National Academy of Sciences of the United States of America   91(23) 11192-11196   Nov 1994   [Refereed]
B. Sebastian; A. Kakizuka; T. Hunter
Proceedings of the National Academy of Sciences of the United States of America   90(8) 3521-3524   Apr 1993   [Refereed]
W.H. Miller Jr.; A. Kakizuka; S.R. Frankel; R.P. Warrell Jr.; A. DeBlasio; K. Levine; R.M. Evans; E. Dmitrovsky
Proceedings of the National Academy of Sciences of the United States of America   89(7) 2694-2698   Apr 1992   [Refereed]

Conference Activities & Talks

 
Challenges for currently incurable disorders. [Invited]
Akira Kakizuka
The Liaison Laboratory regular seminar/ HIGO Program cutting-edge research seminar.   21 Jan 2015   
VCP, a Major ATPase in the Cells, as a Novel Drug Target for Currently Incurable Disorders [Invited]
Akira Kakizuka
Innovative Medicine: Basic Research and Drug Development. (The Uehara Memorial Foundation Symposium 2014   15 Jun 2014   
Roles of VCP in neurodegenerative disorders.
The 10th NTU-Japan International mini- symposium on Molecular and Cell biology & promotion of Academic Exchange and Collaborations for NTU-Japan.   8 Jan 2012   Kyoto University, Taiwan National University
Roles of VCP in human neurodegenerative disorders.
Kyoto University day in Nanjing.   2 Dec 2011   Kyoto University, Nanjing University
Roles of VCP in polyglutamine diseases.
Asian Aging Core for Longevity (AACL)-Nagasaki Symposium Asian Aging 2011: Japan-Korea Joint Conference on Brain Aging and Neurodegeneration (Molecular Perspectives and Regional Bridging).   21 Nov 2011   
Roles of VCP in abnormal phospholipid metabolisms in polyglutamine disease models.
9th International conference on AAA proteins   10 Nov 2011   AAA proteins
A novel feedback machinery between abnormal protein accumulation and transcriptional suppression
The 5th NTU-Kyoto-U mini-symposium on molecular and cellular biology   23 May 2009   
Roles of VCP in human neurodegenerative disorders
7th international conference on AAA proteins   11 Sep 2007   AAA proteins