論文

査読有り
2016年2月

Bioactive treatment promotes osteoblast differentiation on titanium materials fabricated by selective laser melting technology

DENTAL MATERIALS JOURNAL
  • Masako Tsukanaka
  • ,
  • Shunsuke Fujibayashi
  • ,
  • Mitsuru Takemoto
  • ,
  • Tomiharu Matsushita
  • ,
  • Tadashi Kokubo
  • ,
  • Takashi Nakamura
  • ,
  • Kiyoyuki Sasaki
  • ,
  • Shuichi Matsuda

35
1
開始ページ
118
終了ページ
125
記述言語
英語
掲載種別
研究論文(学術雑誌)
DOI
10.4012/dmj.2015-127
出版者・発行元
JAPANESE SOC DENTAL MATERIALS DEVICES

Selective laser melting (SLM) technology is useful for the fabrication of porous titanium implants with complex shapes and structures. The materials fabricated by SLM characteristically have a very rough surface (average surface roughness, Ra=24.58 mu m). In this study, we evaluated morphologically and biochemically the specific effects of this very rough surface and the additional effects of a bioactive treatment on osteoblast proliferation and differentiation. Flat-rolled titanium materials (Ra=1.02 mu m) were used as the controls. On the treated materials fabricated by SLM, we observed enhanced osteoblast differentiation compared with the flat-rolled materials and the untreated materials fabricated by SLM. No significant differences were observed between the flat-rolled materials and the untreated materials fabricated by SLM in their effects on osteoblast differentiation. We concluded that the very rough surface fabricated by SLM had to undergo a bioactive treatment to obtain a positive effect on osteoblast differentiation.

リンク情報
DOI
https://doi.org/10.4012/dmj.2015-127
J-GLOBAL
https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201602209209877337
PubMed
https://www.ncbi.nlm.nih.gov/pubmed/26830832
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000373243300016&DestApp=WOS_CPL
ID情報
  • DOI : 10.4012/dmj.2015-127
  • ISSN : 0287-4547
  • J-Global ID : 201602209209877337
  • PubMed ID : 26830832
  • Web of Science ID : WOS:000373243300016

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