2016年2月
Bioactive treatment promotes osteoblast differentiation on titanium materials fabricated by selective laser melting technology
DENTAL MATERIALS JOURNAL
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- 巻
- 35
- 号
- 1
- 開始ページ
- 118
- 終了ページ
- 125
- 記述言語
- 英語
- 掲載種別
- 研究論文(学術雑誌)
- DOI
- 10.4012/dmj.2015-127
- 出版者・発行元
- JAPANESE SOC DENTAL MATERIALS DEVICES
Selective laser melting (SLM) technology is useful for the fabrication of porous titanium implants with complex shapes and structures. The materials fabricated by SLM characteristically have a very rough surface (average surface roughness, Ra=24.58 mu m). In this study, we evaluated morphologically and biochemically the specific effects of this very rough surface and the additional effects of a bioactive treatment on osteoblast proliferation and differentiation. Flat-rolled titanium materials (Ra=1.02 mu m) were used as the controls. On the treated materials fabricated by SLM, we observed enhanced osteoblast differentiation compared with the flat-rolled materials and the untreated materials fabricated by SLM. No significant differences were observed between the flat-rolled materials and the untreated materials fabricated by SLM in their effects on osteoblast differentiation. We concluded that the very rough surface fabricated by SLM had to undergo a bioactive treatment to obtain a positive effect on osteoblast differentiation.
- リンク情報
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- DOI
- https://doi.org/10.4012/dmj.2015-127
- J-GLOBAL
- https://jglobal.jst.go.jp/detail?JGLOBAL_ID=201602209209877337
- PubMed
- https://www.ncbi.nlm.nih.gov/pubmed/26830832
- Web of Science
- https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000373243300016&DestApp=WOS_CPL
- ID情報
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- DOI : 10.4012/dmj.2015-127
- ISSN : 0287-4547
- J-Global ID : 201602209209877337
- PubMed ID : 26830832
- Web of Science ID : WOS:000373243300016