2002年
Significance of the p53 status of the tumor cells in neutron captutre therapy
RESEARCH AND DEVELOPMENT IN NEUTRON CAPTURE THERAPY
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- 開始ページ
- 739
- 終了ページ
- 743
- 記述言語
- 英語
- 掲載種別
- 出版者・発行元
- MEDIMOND S R L
The p53 status of the tumor cells had the potential to influence the way, to, respond to radiation dose delivered by neutron capture reaction in vivo. In contrast with reactor neutron beam irradiation alone which reduces the difference in sensitivity to gamma-rays between total and quiescent (Q) cells, more radiation doses to Q cells are needed to achieve the equivalent endpoint obtain in total cells when combined with B-10-carrier administration irrespective of the p53 status. The apoptosis frequency, as well, as,the MN frequency, can be applied to our method for measuring the Q cell response to reactor neutron beam irradiation within solid tumors.
- リンク情報
- ID情報
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- Web of Science ID : WOS:000178661500127