MISC

2002年

Significance of the p53 status of the tumor cells in neutron captutre therapy

RESEARCH AND DEVELOPMENT IN NEUTRON CAPTURE THERAPY
  • S Masunaga
  • ,
  • K Ono
  • ,
  • A Takahashi
  • ,
  • Y Sakurai
  • ,
  • T Kobayashi
  • ,
  • Y Kinashi
  • ,
  • T Ohnishi

開始ページ
739
終了ページ
743
記述言語
英語
掲載種別
出版者・発行元
MEDIMOND S R L

The p53 status of the tumor cells had the potential to influence the way, to, respond to radiation dose delivered by neutron capture reaction in vivo. In contrast with reactor neutron beam irradiation alone which reduces the difference in sensitivity to gamma-rays between total and quiescent (Q) cells, more radiation doses to Q cells are needed to achieve the equivalent endpoint obtain in total cells when combined with B-10-carrier administration irrespective of the p53 status. The apoptosis frequency, as well, as,the MN frequency, can be applied to our method for measuring the Q cell response to reactor neutron beam irradiation within solid tumors.

リンク情報
Web of Science
https://gateway.webofknowledge.com/gateway/Gateway.cgi?GWVersion=2&SrcAuth=JSTA_CEL&SrcApp=J_Gate_JST&DestLinkType=FullRecord&KeyUT=WOS:000178661500127&DestApp=WOS_CPL
ID情報
  • Web of Science ID : WOS:000178661500127

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